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Items: 1 to 50 of 134

1.

PluS Nanoparticles Loaded with Sorafenib: Synthetic Approach and Their Effects on Endothelial Cells.

Palomba F, Genovese D, Rampazzo E, Zaccheroni N, Prodi L, Morbidelli L.

ACS Omega. 2019 Aug 14;4(9):13962-13971. doi: 10.1021/acsomega.9b01699. eCollection 2019 Aug 27.

2.

Effect of NIR laser therapy by MLS-MiS source against neuropathic pain in rats: in vivo and ex vivo analysis.

Micheli L, Cialdai F, Pacini A, Branca JJV, Morbidelli L, Ciccone V, Lucarini E, Ghelardini C, Monici M, Di Cesare Mannelli L.

Sci Rep. 2019 Jun 26;9(1):9297. doi: 10.1038/s41598-019-45469-5.

3.

mPGES-1 as a new target to overcome acquired resistance to gefitinib in non-small cell lung cancer cell lines.

Terzuoli E, Costanza F, Ciccone V, Ziche M, Morbidelli L, Donnini S.

Prostaglandins Other Lipid Mediat. 2019 Aug;143:106344. doi: 10.1016/j.prostaglandins.2019.106344. Epub 2019 Jun 15.

PMID:
31207300
4.

Pharmacological Tools for the Study of H2S Contribution to Angiogenesis.

Morbidelli L, Monti M, Terzuoli E.

Methods Mol Biol. 2019;2007:151-166. doi: 10.1007/978-1-4939-9528-8_11.

PMID:
31148112
5.

Targeting endothelial-to-mesenchymal transition: the protective role of hydroxytyrosol sulfate metabolite.

Terzuoli E, Nannelli G, Giachetti A, Morbidelli L, Ziche M, Donnini S.

Eur J Nutr. 2019 Feb 6. doi: 10.1007/s00394-019-01920-x. [Epub ahead of print]

PMID:
30725211
6.

Correction to: Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells.

Ciccone V, Terzuoli E, Donnini S, Giachetti A, Morbidelli L, Ziche M.

J Exp Clin Cancer Res. 2019 Feb 1;38(1):45. doi: 10.1186/s13046-019-1045-y.

7.

Stemness marker ALDH1A1 promotes tumor angiogenesis via retinoic acid/HIF-1α/VEGF signalling in MCF-7 breast cancer cells.

Ciccone V, Terzuoli E, Donnini S, Giachetti A, Morbidelli L, Ziche M.

J Exp Clin Cancer Res. 2018 Dec 12;37(1):311. doi: 10.1186/s13046-018-0975-0. Erratum in: J Exp Clin Cancer Res. 2019 Feb 1;38(1):45.

8.

Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents.

Brindisi M, Ulivieri C, Alfano G, Gemma S, de Asís Balaguer F, Khan T, Grillo A, Chemi G, Menchon G, Prota AE, Olieric N, Lucena-Agell D, Barasoain I, Diaz JF, Nebbioso A, Conte M, Lopresti L, Magnano S, Amet R, Kinsella P, Zisterer DM, Ibrahim O, O'Sullivan J, Morbidelli L, Spaccapelo R, Baldari C, Butini S, Novellino E, Campiani G, Altucci L, Steinmetz MO, Brogi S.

Eur J Med Chem. 2019 Jan 15;162:290-320. doi: 10.1016/j.ejmech.2018.11.004. Epub 2018 Nov 3.

PMID:
30448418
9.

Use of Nutraceuticals in Angiogenesis-Dependent Disorders.

Morbidelli L, Terzuoli E, Donnini S.

Molecules. 2018 Oct 18;23(10). pii: E2676. doi: 10.3390/molecules23102676. Review.

10.

Peptides derived from the histidine-proline rich glycoprotein bind copper ions and exhibit anti-angiogenic properties.

Magrì A, Grasso G, Corti F, Finetti F, Greco V, Santoro AM, Sciuto S, La Mendola D, Morbidelli L, Rizzarelli E.

Dalton Trans. 2018 Jul 17;47(28):9492-9503. doi: 10.1039/c8dt01560k.

PMID:
29963662
11.

Impaired Cerebral Perfusion in Multiple Sclerosis: Relevance of Endothelial Factors.

Monti L, Morbidelli L, Rossi A.

Biomark Insights. 2018 May 18;13:1177271918774800. doi: 10.1177/1177271918774800. eCollection 2018. Review.

12.

Cross-talk between endogenous H2S and NO accounts for vascular protective activity of the metal-nonoate Zn(PipNONO)Cl.

Monti M, Hyseni I, Pacini A, Monzani E, Casella L, Morbidelli L.

Biochem Pharmacol. 2018 Jun;152:143-152. doi: 10.1016/j.bcp.2018.03.025. Epub 2018 Mar 26.

PMID:
29588193
13.

The metal-nonoate Ni(SalPipNONO) inhibits in vitro tumor growth, invasiveness and angiogenesis.

Ciccone V, Monti M, Monzani E, Casella L, Morbidelli L.

Oncotarget. 2018 Jan 30;9(17):13353-13365. doi: 10.18632/oncotarget.24350. eCollection 2018 Mar 2.

14.

Involvement of Bradykinin B2 Receptor in Pathological Vascularization in Oxygen-Induced Retinopathy in Mice and Rabbit Cornea.

Terzuoli E, Morbidelli L, Nannelli G, Giachetti A, Donnini S, Ziche M.

Int J Mol Sci. 2018 Jan 23;19(2). pii: E330. doi: 10.3390/ijms19020330.

15.

Influence of Circulating Endothelin-1 and Asymmetric Dimethylarginine on Whole Brain Circulation Time in Multiple Sclerosis.

Monti L, Morbidelli L, Bazzani L, Rossi A.

Biomark Insights. 2017 Jun 6;12:1177271917712514. doi: 10.1177/1177271917712514. eCollection 2017.

16.

Pharmacological inhibition of MAGL attenuates experimental colon carcinogenesis.

Pagano E, Borrelli F, Orlando P, Romano B, Monti M, Morbidelli L, Aviello G, Imperatore R, Capasso R, Piscitelli F, Buono L, Di Marzo V, Izzo AA.

Pharmacol Res. 2017 May;119:227-236. doi: 10.1016/j.phrs.2017.02.002. Epub 2017 Feb 11.

PMID:
28193521
17.

Monitoring Endothelial and Tissue Responses to Cobalt Ferrite Nanoparticles and Hybrid Hydrogels.

Finetti F, Terzuoli E, Donnini S, Uva M, Ziche M, Morbidelli L.

PLoS One. 2016 Dec 30;11(12):e0168727. doi: 10.1371/journal.pone.0168727. eCollection 2016.

18.

Efficacy of AdipoDren® in Reducing Interleukin-1-Induced Lymphatic Endothelial Hyperpermeability.

Ciccone V, Monti M, Antonini G, Mattoli L, Burico M, Marini F, Maidecchi A, Morbidelli L.

J Vasc Res. 2016;53(5-6):255-268. doi: 10.1159/000452798. Epub 2016 Dec 7.

19.

Influence of bioactive particles on the chemical-mechanical properties of experimental enamel resin infiltrants.

Sfalcin RA, Correr AB, Morbidelli LR, Araújo TGF, Feitosa VP, Correr-Sobrinho L, Watson TF, Sauro S.

Clin Oral Investig. 2017 Jul;21(6):2143-2151. doi: 10.1007/s00784-016-2005-y. Epub 2016 Nov 12.

PMID:
27838844
20.

VEGF induces signalling and angiogenesis by directing VEGFR2 internalisation through macropinocytosis.

Basagiannis D, Zografou S, Murphy C, Fotsis T, Morbidelli L, Ziche M, Bleck C, Mercer J, Christoforidis S.

J Cell Sci. 2016 Nov 1;129(21):4091-4104. Epub 2016 Sep 21.

21.

H2S dependent and independent anti-inflammatory activity of zofenoprilat in cells of the vascular wall.

Monti M, Terzuoli E, Ziche M, Morbidelli L.

Pharmacol Res. 2016 Nov;113(Pt A):426-437. doi: 10.1016/j.phrs.2016.09.017. Epub 2016 Sep 17.

PMID:
27650753
22.

Miniaturizing VEGF: Peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic response.

De Rosa L, Finetti F, Diana D, Di Stasi R, Auriemma S, Romanelli A, Fattorusso R, Ziche M, Morbidelli L, D'Andrea LD.

Sci Rep. 2016 Aug 8;6:31295. doi: 10.1038/srep31295.

23.

Polyphenol-based nutraceuticals for the control of angiogenesis: Analysis of the critical issues for human use.

Morbidelli L.

Pharmacol Res. 2016 Sep;111:384-393. doi: 10.1016/j.phrs.2016.07.011. Epub 2016 Jul 8. Review.

PMID:
27402192
24.

The Rabbit Corneal Pocket Assay.

Morbidelli L, Ziche M.

Methods Mol Biol. 2016;1430:299-310. doi: 10.1007/978-1-4939-3628-1_20.

PMID:
27172962
25.

Development of novel cyclic peptides as pro-apoptotic agents.

Brindisi M, Maramai S, Brogi S, Fanigliulo E, Butini S, Guarino E, Casagni A, Lamponi S, Bonechi C, Nathwani SM, Finetti F, Ragonese F, Arcidiacono P, Campiglia P, Valenti S, Novellino E, Spaccapelo R, Morbidelli L, Zisterer DM, Williams CD, Donati A, Baldari C, Campiani G, Ulivieri C, Gemma S.

Eur J Med Chem. 2016 Jul 19;117:301-20. doi: 10.1016/j.ejmech.2016.04.001. Epub 2016 Apr 5.

PMID:
27150036
26.

Anti-hypertensive property of a nickel-piperazine/NO donor in spontaneously hypertensive rats.

Monti M, Ciccone V, Pacini A, Roggeri R, Monzani E, Casella L, Morbidelli L.

Pharmacol Res. 2016 May;107:352-359. doi: 10.1016/j.phrs.2016.03.033. Epub 2016 Apr 7.

PMID:
27063892
27.

Therapeutic Potential of Nitric Oxide Donors in Cancer: Focus on Angiogenesis.

Morbidelli L.

Crit Rev Oncog. 2016;21(5-6):447-458. doi: 10.1615/CritRevOncog.2017021114.

PMID:
29431088
28.

Neuronal effects of a nickel-piperazine/NO donor complex in rodents.

Sanna MD, Monti M, Casella L, Roggeri R, Galeotti N, Morbidelli L.

Pharmacol Res. 2015 Sep;99:162-73. doi: 10.1016/j.phrs.2015.06.004. Epub 2015 Jun 18.

PMID:
26094781
29.

Antiangiogenic Effectiveness of the Urokinase Receptor-Derived Peptide UPARANT in a Model of Oxygen-Induced Retinopathy.

Dal Monte M, Rezzola S, Cammalleri M, Belleri M, Locri F, Morbidelli L, Corsini M, Paganini G, Semeraro F, Cancarini A, Rusciano D, Presta M, Bagnoli P.

Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2392-407. doi: 10.1167/iovs.14-16323.

PMID:
25766585
30.

Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy.

Rezzola S, Dal Monte M, Belleri M, Bugatti A, Chiodelli P, Corsini M, Cammalleri M, Cancarini A, Morbidelli L, Oreste P, Bagnoli P, Semeraro F, Presta M.

Diabetes. 2015 Jul;64(7):2581-92. doi: 10.2337/db14-1378. Epub 2015 Feb 18.

31.

Cerebral circulation time is prolonged and not correlated with EDSS in multiple sclerosis patients: a study using digital subtracted angiography.

Monti L, Donati D, Menci E, Cioni S, Bellini M, Grazzini I, Leonini S, Galluzzi P, Bracco S, Severi S, Burroni L, Casasco A, Morbidelli L, Santarnecchi E, Piu P.

PLoS One. 2015 Feb 13;10(2):e0116681. doi: 10.1371/journal.pone.0116681. eCollection 2015. Erratum in: PLoS One. 2015;10(3):e0123731. Bracco, Sandra [added].

32.

The impact of microgravity and hypergravity on endothelial cells.

Maier JA, Cialdai F, Monici M, Morbidelli L.

Biomed Res Int. 2015;2015:434803. doi: 10.1155/2015/434803. Epub 2015 Jan 13. Review.

33.

Characterization of zofenoprilat as an inducer of functional angiogenesis through increased H2 S availability.

Terzuoli E, Monti M, Vellecco V, Bucci M, Cirino G, Ziche M, Morbidelli L.

Br J Pharmacol. 2015 Jun;172(12):2961-73. doi: 10.1111/bph.13101. Epub 2015 Mar 27.

34.

The corneal pocket assay.

Ziche M, Morbidelli L.

Methods Mol Biol. 2015;1214:15-28. doi: 10.1007/978-1-4939-1462-3_2.

PMID:
25468596
35.

Protective effects of novel metal-nonoates on the cellular components of the vascular system.

Monti M, Solito R, Puccetti L, Pasotti L, Roggeri R, Monzani E, Casella L, Morbidelli L.

J Pharmacol Exp Ther. 2014 Dec;351(3):500-9. doi: 10.1124/jpet.114.218404. Epub 2014 Sep 19.

PMID:
25238748
36.

The sulphydryl containing ACE inhibitor Zofenoprilat protects coronary endothelium from Doxorubicin-induced apoptosis.

Monti M, Terzuoli E, Ziche M, Morbidelli L.

Pharmacol Res. 2013 Oct;76:171-81. doi: 10.1016/j.phrs.2013.08.003. Epub 2013 Aug 18.

PMID:
23965518
37.

PKCε activation promotes FGF-2 exocytosis and induces endothelial cell proliferation and sprouting.

Monti M, Donnini S, Morbidelli L, Giachetti A, Mochly-Rosen D, Mignatti P, Ziche M.

J Mol Cell Cardiol. 2013 Oct;63:107-17. doi: 10.1016/j.yjmcc.2013.07.006. Epub 2013 Jul 20.

38.

The isoflavone metabolite 6-methoxyequol inhibits angiogenesis and suppresses tumor growth.

Bellou S, Karali E, Bagli E, Al-Maharik N, Morbidelli L, Ziche M, Adlercreutz H, Murphy C, Fotsis T.

Mol Cancer. 2012 May 14;11:35. doi: 10.1186/1476-4598-11-35.

39.

Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis.

Finetti F, Basile A, Capasso D, Di Gaetano S, Di Stasi R, Pascale M, Turco CM, Ziche M, Morbidelli L, D'Andrea LD.

Biochem Pharmacol. 2012 Aug 1;84(3):303-11. doi: 10.1016/j.bcp.2012.04.011. Epub 2012 Apr 21.

PMID:
22554565
40.

Genetic and pharmacologic inactivation of cannabinoid CB1 receptor inhibits angiogenesis.

Pisanti S, Picardi P, Prota L, Proto MC, Laezza C, McGuire PG, Morbidelli L, Gazzerro P, Ziche M, Das A, Bifulco M.

Blood. 2011 May 19;117(20):5541-50. doi: 10.1182/blood-2010-09-307355. Epub 2011 Apr 1.

PMID:
21460248
41.

Non-peptide NK1 receptor ligands based on the 4-phenylpyridine moiety.

Giuliani G, Cappelli A, Matarrese M, Masiello V, Turolla EA, Monterisi C, Fazio F, Anzini M, Pericot Mohr G, Riitano D, Finetti F, Morbidelli L, Ziche M, Giorgi G, Vomero S.

Bioorg Med Chem. 2011 Apr 1;19(7):2242-51. doi: 10.1016/j.bmc.2011.02.031. Epub 2011 Feb 24.

PMID:
21421318
42.

The natural compound n-butylidenephthalide derived from the volatile oil of Radix Angelica sinensis inhibits angiogenesis in vitro and in vivo.

Yeh JC, Cindrova-Davies T, Belleri M, Morbidelli L, Miller N, Cho CW, Chan K, Wang YT, Luo GA, Ziche M, Presta M, Charnock-Jones DS, Fan TP.

Angiogenesis. 2011 May;14(2):187-97. doi: 10.1007/s10456-011-9202-8. Epub 2011 Feb 15.

PMID:
21327473
43.

PKG-I inhibition attenuates vascular endothelial growth factor-stimulated angiogenesis.

Koika V, Zhou Z, Vasileiadis I, Roussos C, Finetti F, Monti M, Morbidelli L, Papapetropoulos A.

Vascul Pharmacol. 2010 Nov-Dec;53(5-6):215-22. doi: 10.1016/j.vph.2010.08.004. Epub 2010 Sep 8.

PMID:
20813203
44.

Molecular regulation of tumour angiogenesis by nitric oxide.

Ziche M, Morbidelli L.

Eur Cytokine Netw. 2009 Dec;20(4):164-70. doi: 10.1684/ecn.2009.0169. Review.

45.

The soluble guanylyl cyclase inhibitor NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability.

Morbidelli L, Pyriochou A, Filippi S, Vasileiadis I, Roussos C, Zhou Z, Loutrari H, Waltenberger J, Stössel A, Giannis A, Ziche M, Papapetropoulos A.

Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R824-32. doi: 10.1152/ajpregu.00222.2009. Epub 2009 Dec 23.

46.

Sulfhydryl angiotensin-converting enzyme inhibitor promotes endothelial cell survival through nitric-oxide synthase, fibroblast growth factor-2, and telomerase cross-talk.

Donnini S, Terzuoli E, Ziche M, Morbidelli L.

J Pharmacol Exp Ther. 2010 Mar;332(3):776-84. doi: 10.1124/jpet.109.159178. Epub 2009 Dec 3.

PMID:
19959747
47.

Prostaglandin E(2) primes the angiogenic switch via a synergic interaction with the fibroblast growth factor-2 pathway.

Finetti F, Donnini S, Giachetti A, Morbidelli L, Ziche M.

Circ Res. 2009 Sep 25;105(7):657-66. doi: 10.1161/CIRCRESAHA.109.203760. Epub 2009 Aug 27.

PMID:
19713533
48.

The corneal pocket assay.

Ziche M, Morbidelli L.

Methods Mol Biol. 2009;467:319-29. doi: 10.1007/978-1-59745-241-0_20.

PMID:
19301681
49.

Hydrocaffeic and p-coumaric acids, natural phenolic compounds, inhibit UV-B damage in WKD human conjunctival cells in vitro and rabbit eye in vivo.

Larrosa M, Lodovici M, Morbidelli L, Dolara P.

Free Radic Res. 2008 Oct;42(10):903-10. doi: 10.1080/10715760802510077.

PMID:
18985489
50.

Protective effect of 4-coumaric acid from UVB ray damage in the rabbit eye.

Lodovici M, Caldini S, Morbidelli L, Akpan V, Ziche M, Dolara P.

Toxicology. 2009 Jan 8;255(1-2):1-5. doi: 10.1016/j.tox.2008.09.011. Epub 2008 Sep 25.

PMID:
18852014

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