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Items: 1 to 50 of 66

1.

Retraction: Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition.

Amara K, Steen J, Murray F, Morbach H, Fernandez-Rodriguez BM, Joshua V, Engström M, Snir O, Israelsson L, Catrina AI, Wardemann H, Corti D, Meffre E, Klareskog L, Malmström V.

J Exp Med. 2019 Jan 7;216(1):245. doi: 10.1084/jem.2012148612112018r. Epub 2018 Dec 19. No abstract available.

2.

CD14+ monocytes contribute to inflammation in chronic nonbacterial osteomyelitis (CNO) through increased NLRP3 inflammasome expression.

Brandt D, Sohr E, Pablik J, Schnabel A, Kapplusch F, Mäbert K, Girschick JH, Morbach H, Thielemann F, Hofmann SR, Hedrich CM.

Clin Immunol. 2018 Nov;196:77-84. doi: 10.1016/j.clim.2018.04.011. Epub 2018 Apr 30.

PMID:
29723617
3.

Serum Interleukin-6 and CCL11/Eotaxin May Be Suitable Biomarkers for the Diagnosis of Chronic Nonbacterial Osteomyelitis.

Hofmann SR, Böttger F, Range U, Lück C, Morbach H, Girschick HJ, Suttorp M, Hedrich CM.

Front Pediatr. 2017 Dec 1;5:256. doi: 10.3389/fped.2017.00256. eCollection 2017.

4.

Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment.

Hofmann SR, Kapplusch F, Girschick HJ, Morbach H, Pablik J, Ferguson PJ, Hedrich CM.

Curr Osteoporos Rep. 2017 Dec;15(6):542-554. doi: 10.1007/s11914-017-0405-9. Review.

5.

Chronic Nonbacterial Osteomyelitis: Pathophysiological Concepts and Current Treatment Strategies.

Hofmann SR, Schnabel A, Rösen-Wolff A, Morbach H, Girschick HJ, Hedrich CM.

J Rheumatol. 2016 Nov;43(11):1956-1964. Epub 2016 Sep 1. Review.

PMID:
27585682
6.

Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.

Massaad MJ, Zhou J, Tsuchimoto D, Chou J, Jabara H, Janssen E, Glauzy S, Olson BG, Morbach H, Ohsumi TK, Schmitz K, Kyriacos M, Kane J, Torisu K, Nakabeppu Y, Notarangelo LD, Chouery E, Megarbane A, Kang PB, Al-Idrissi E, Aldhekri H, Meffre E, Mizui M, Tsokos GC, Manis JP, Al-Herz W, Wallace SS, Geha RS.

J Clin Invest. 2016 Nov 1;126(11):4219-4236. doi: 10.1172/JCI85647. Epub 2016 Oct 17.

7.

Compromised fidelity of B-cell tolerance checkpoints in AChR and MuSK myasthenia gravis.

Lee JY, Stathopoulos P, Gupta S, Bannock JM, Barohn RJ, Cotzomi E, Dimachkie MM, Jacobson L, Lee CS, Morbach H, Querol L, Shan JL, Vander Heiden JA, Waters P, Vincent A, Nowak RJ, O'Connor KC.

Ann Clin Transl Neurol. 2016 Apr 27;3(6):443-54. doi: 10.1002/acn3.311. eCollection 2016 Jun.

8.

Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO).

Hofmann SR, Kubasch AS, Range U, Laass MW, Morbach H, Girschick HJ, Hedrich CM.

Rheumatol Int. 2016 Jun;36(6):769-79. doi: 10.1007/s00296-016-3466-7. Epub 2016 Mar 21.

PMID:
27000045
9.

No association of IL-12p40 pro1.1 polymorphism with juvenile idiopathic arthritis.

Eberhardt CS, Haas JP, Girschick H, Schwarz T, Morbach H, Rösen-Wolff A, Foell D, Dannecker G, Schepp C, Ganser G, Honke N, Eggermann T, Müller-Berghaus J, Wagner N, Ohl K, Tenbrock K.

Pediatr Rheumatol Online J. 2015 Dec 15;13:61. doi: 10.1186/s12969-015-0059-z.

10.

CD19 controls Toll-like receptor 9 responses in human B cells.

Morbach H, Schickel JN, Cunningham-Rundles C, Conley ME, Reisli I, Franco JL, Meffre E.

J Allergy Clin Immunol. 2016 Mar;137(3):889-98.e6. doi: 10.1016/j.jaci.2015.08.040. Epub 2015 Oct 21.

11.

Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1β expression and release.

Hofmann SR, Kubasch AS, Ioannidis C, Rösen-Wolff A, Girschick HJ, Morbach H, Hedrich CM.

Clin Immunol. 2015 Dec;161(2):300-7. doi: 10.1016/j.clim.2015.09.013. Epub 2015 Sep 25.

PMID:
26404542
12.

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.

Pala F, Morbach H, Castiello MC, Schickel JN, Scaramuzza S, Chamberlain N, Cassani B, Glauzy S, Romberg N, Candotti F, Aiuti A, Bosticardo M, Villa A, Meffre E.

J Clin Invest. 2015 Oct 1;125(10):3941-51. doi: 10.1172/JCI82249. Epub 2015 Sep 14.

13.

Severe immune dysregulation with neurological impairment and minor bone changes in a child with spondyloenchondrodysplasia due to two novel mutations in the ACP5 gene.

Girschick H, Wolf C, Morbach H, Hertzberg C, Lee-Kirsch MA.

Pediatr Rheumatol Online J. 2015 Sep 7;13(1):37. doi: 10.1186/s12969-015-0035-7.

14.

Corrigendum: Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect.

Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B.

Nat Commun. 2015 Mar 6;6:6507. doi: 10.1038/ncomms7507. No abstract available.

15.

Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells.

Janssen E, Morbach H, Ullas S, Bannock JM, Massad C, Menard L, Barlan I, Lefranc G, Su H, Dasouki M, Al-Herz W, Keles S, Chatila T, Geha RS, Meffre E.

J Allergy Clin Immunol. 2014 Dec;134(6):1365-1374. doi: 10.1016/j.jaci.2014.07.042. Epub 2014 Sep 11.

16.

Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect.

Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B.

Nat Commun. 2014 Sep 4;5:4746. doi: 10.1038/ncomms5746. Erratum in: Nat Commun. 2015;6:6507. Heinze, Katrin [corrected to Heinze, Katrin G].

PMID:
25187265
17.

A standardized clinical and radiological follow-up of patients with chronic non-bacterial osteomyelitis treated with pamidronate.

Hofmann C, Wurm M, Schwarz T, Neubauer H, Beer M, Girschick H, Morbach H.

Clin Exp Rheumatol. 2014 Jul-Aug;32(4):604-9. Epub 2014 Jul 23.

PMID:
25065777
18.

A 58-year-old man with respiratory insufficiency after a 50-year history of hypersensitivity pneumonitis and pulmonary Aspergillus infections.

Segerer F, Morbach H, Hassold N, Kleinert S, Tony HP, Roesler J, Liese J.

J Allergy Clin Immunol Pract. 2013 Nov-Dec;1(6):677-80. doi: 10.1016/j.jaip.2013.09.001. Epub 2013 Oct 31. No abstract available.

PMID:
24565717
19.

Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO).

Hedrich CM, Hofmann SR, Pablik J, Morbach H, Girschick HJ.

Pediatr Rheumatol Online J. 2013 Dec 23;11(1):47. doi: 10.1186/1546-0096-11-47.

20.

A clinical and pathomechanistic profile of chronic nonbacterial osteomyelitis/chronic recurrent multifocal osteomyelitis and challenges facing the field.

Hedrich CM, Hahn G, Girschick HJ, Morbach H.

Expert Rev Clin Immunol. 2013 Sep;9(9):845-54. doi: 10.1586/1744666X.2013.824670. Review.

PMID:
24070048
21.

CVID-associated TACI mutations affect autoreactive B cell selection and activation.

Romberg N, Chamberlain N, Saadoun D, Gentile M, Kinnunen T, Ng YS, Virdee M, Menard L, Cantaert T, Morbach H, Rachid R, Martinez-Pomar N, Matamoros N, Geha R, Grimbacher B, Cerutti A, Cunningham-Rundles C, Meffre E.

J Clin Invest. 2013 Oct;123(10):4283-93. doi: 10.1172/JCI69854. Epub 2013 Sep 24.

22.

Impaired B-cell reconstitution in children after chemotherapy for standard or medium risk acute precursor B-lymphoblastic leukemia.

Wiegering V, Frank J, Freudenberg S, Morbach H, Schlegel PG, Eyrich M, Winkler B.

Leuk Lymphoma. 2014 Apr;55(4):870-5. doi: 10.3109/10428194.2013.816423. Epub 2013 Jul 25.

PMID:
23786458
23.

Specific peripheral B cell tolerance defects in patients with multiple sclerosis.

Kinnunen T, Chamberlain N, Morbach H, Cantaert T, Lynch M, Preston-Hurlburt P, Herold KC, Hafler DA, O'Connor KC, Meffre E.

J Clin Invest. 2013 Jun;123(6):2737-41. doi: 10.1172/JCI68775. Epub 2013 May 15.

24.

[B-cell targeted therapy for children and adolescents with rheumatic diseases].

Morbach H, Girschick HJ.

Z Rheumatol. 2013 May;72(4):347-53. doi: 10.1007/s00393-012-1064-y. German.

PMID:
23609932
25.

Even in pneumococcal sepsis CD62L shedding on granulocytes proves to be a reliable functional test for the diagnosis of interleukin-1 receptor-associated kinase-4 deficiency.

Andres O, Strehl K, Kölsch U, Kunzmann S, Lebrun AH, Stroh T, Schwarz K, Morbach H, von Bernuth H, Liese J.

Pediatr Infect Dis J. 2013 Sep;32(9):1017-9. doi: 10.1097/INF.0b013e318292bf8c. Erratum in: Pediatr Infect Dis J. 2013 Nov;32(11):1302. Liefse, Johannes [corrected to Liese, Johannes].

PMID:
23538514
26.

Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition.

Amara K, Steen J, Murray F, Morbach H, Fernandez-Rodriguez BM, Joshua V, Engström M, Snir O, Israelsson L, Catrina AI, Wardemann H, Corti D, Meffre E, Klareskog L, Malmström V.

J Exp Med. 2013 Mar 11;210(3):445-55. doi: 10.1084/jem.20121486. Epub 2013 Feb 25. Retraction in: J Exp Med. 2019 Jan 7;216(1):245.

27.

Gain-of-function STAT1 mutations are associated with PD-L1 overexpression and a defect in B-cell survival.

Romberg N, Morbach H, Lawrence MG, Kim S, Kang I, Holland SM, Milner JD, Meffre E.

J Allergy Clin Immunol. 2013 Jun;131(6):1691-3. doi: 10.1016/j.jaci.2013.01.004. Epub 2013 Feb 10. No abstract available. Erratum in: J Allergy Clin Immunol. 2013 Dec;132(6):1460.

28.

Autoinflammatory bone disorders.

Morbach H, Hedrich CM, Beer M, Girschick HJ.

Clin Immunol. 2013 Jun;147(3):185-96. doi: 10.1016/j.clim.2012.12.012. Epub 2013 Jan 5. Review.

PMID:
23369460
29.

Chronic non-bacterial osteomyelitis in childhood - a comprehensive review.

Morbach H, Girschick HJ.

Curr Rheumatol Rev. 2013;9(1):17-21.

PMID:
25198363
30.

Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells.

Kinnunen T, Chamberlain N, Morbach H, Choi J, Kim S, Craft J, Mayer L, Cancrini C, Passerini L, Bacchetta R, Ochs HD, Torgerson TR, Meffre E.

Blood. 2013 Feb 28;121(9):1595-603. doi: 10.1182/blood-2012-09-457465. Epub 2012 Dec 5.

31.

Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression.

Hofmann SR, Morbach H, Schwarz T, Rösen-Wolff A, Girschick HJ, Hedrich CM.

Clin Immunol. 2012 Oct;145(1):69-76. doi: 10.1016/j.clim.2012.07.012. Epub 2012 Aug 4.

PMID:
22940633
32.

Diffusion-weighted MRI of bone marrow oedema, soft tissue oedema and synovitis in paediatric patients: feasibility and initial experience.

Neubauer H, Evangelista L, Morbach H, Girschick H, Prelog M, Köstler H, Hahn D, Beer M.

Pediatr Rheumatol Online J. 2012 Jul 31;10(1):20. doi: 10.1186/1546-0096-10-20.

33.

Comparison of magnetic resonance imaging and 99mTechnetium-labelled methylene diphosphonate bone scintigraphy in the initial assessment of chronic non-bacterial osteomyelitis of childhood and adolescents.

Morbach H, Schneider P, Schwarz T, Hofmann C, Raab P, Neubauer H, Düren C, Beer M, Girschick HJ.

Clin Exp Rheumatol. 2012 Jul-Aug;30(4):578-82. Epub 2012 Aug 29.

PMID:
22765947
34.

Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy.

Sauer AV, Morbach H, Brigida I, Ng YS, Aiuti A, Meffre E.

J Clin Invest. 2012 Jun;122(6):2141-52. doi: 10.1172/JCI61788. Epub 2012 May 24.

35.

P67-phox (NCF2) lacking exons 11 and 12 is functionally active and leads to an extremely late diagnosis of chronic granulomatous disease (CGD).

Roesler J, Segerer F, Morbach H, Kleinert S, Thieme S, Rösen-Wolff A, Liese JG.

PLoS One. 2012;7(4):e34296. doi: 10.1371/journal.pone.0034296. Epub 2012 Apr 13.

36.

Popliteal cysts in paediatric patients: clinical characteristics and imaging features on ultrasound and MRI.

Neubauer H, Morbach H, Schwarz T, Wirth C, Girschick H, Beer M.

Arthritis. 2011;2011:751593. doi: 10.1155/2011/751593. Epub 2011 May 5.

37.

Mutation screening of the IL-1 receptor antagonist gene in chronic non-bacterial osteomyelitis of childhood and adolescence.

Beck C, Girschick HJ, Morbach H, Schwarz T, Yimam T, Frenkel J, van Gijn ME.

Clin Exp Rheumatol. 2011 Nov-Dec;29(6):1040-3. Epub 2011 Dec 22.

PMID:
22032624
38.

Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced IL10 promoter phosphorylation, and reduced myeloid IL-10 expression.

Hofmann SR, Schwarz T, Möller JC, Morbach H, Schnabel A, Rösen-Wolff A, Girschick HJ, Hedrich CM.

Clin Immunol. 2011 Dec;141(3):317-27. doi: 10.1016/j.clim.2011.08.012. Epub 2011 Aug 30.

PMID:
21925952
39.

Activated memory B cells may function as antigen-presenting cells in the joints of children with juvenile idiopathic arthritis.

Morbach H, Wiegering V, Richl P, Schwarz T, Suffa N, Eichhorn EM, Eyrich M, Girschick HJ.

Arthritis Rheum. 2011 Nov;63(11):3458-66. doi: 10.1002/art.30569.

40.

Gastroenteritis in childhood: a retrospective study of 650 hospitalized pediatric patients.

Wiegering V, Kaiser J, Tappe D, Weissbrich B, Morbach H, Girschick HJ.

Int J Infect Dis. 2011 Jun;15(6):e401-7. doi: 10.1016/j.ijid.2011.02.006. Epub 2011 Apr 12.

41.

Primary hypertrophic osteoarthropathy with digital clubbing and palmoplantar hyperhidrosis caused by 15-PGHD/HPGD loss-of-function mutations.

Bergmann C, Wobser M, Morbach H, Falkenbach A, Wittenhagen D, Lassay L, Ott H, Zerres K, Girschick HJ, Hamm H.

Exp Dermatol. 2011 Jun;20(6):531-3. doi: 10.1111/j.1600-0625.2011.01248.x. Epub 2011 Mar 23.

PMID:
21426412
42.

Primed tumor-reactive multifunctional CD62L+ human CD8+ T cells for immunotherapy.

Wölfl M, Merker K, Morbach H, Van Gool SW, Eyrich M, Greenberg PD, Schlegel PG.

Cancer Immunol Immunother. 2011 Feb;60(2):173-86. doi: 10.1007/s00262-010-0928-8. Epub 2010 Oct 24.

43.

Reference values for B cell subpopulations from infancy to adulthood.

Morbach H, Eichhorn EM, Liese JG, Girschick HJ.

Clin Exp Immunol. 2010 Nov;162(2):271-9. doi: 10.1111/j.1365-2249.2010.04206.x. Epub 2010 Sep 20.

44.

Prevalence of antibodies against mutated citrullinated vimentin and cyclic citrullinated peptide in children with juvenile idiopathic arthritis.

Morbach H, Dannecker H, Kerkau T, Girschick HJ.

Clin Exp Rheumatol. 2010 Sep-Oct;28(5):800. Epub 2010 Oct 22. No abstract available.

PMID:
20822716
45.

Chronic nonbacterial osteomyelitis in childhood: prospective follow-up during the first year of anti-inflammatory treatment.

Beck C, Morbach H, Beer M, Stenzel M, Tappe D, Gattenlöhner S, Hofmann U, Raab P, Girschick HJ.

Arthritis Res Ther. 2010;12(2):R74. doi: 10.1186/ar2992.

46.

Whole-body MRI in the childhood form of hypophosphatasia.

Beck C, Morbach H, Wirth C, Beer M, Girschick HJ.

Rheumatol Int. 2011 Oct;31(10):1315-20. doi: 10.1007/s00296-010-1493-3. Epub 2010 Apr 10.

PMID:
20383509
47.

Sporadic Blau syndrome with onset of widespread granulomatous dermatitis in the newborn period.

Stoevesandt J, Morbach H, Martin TM, Zierhut M, Girschick H, Hamm H.

Pediatr Dermatol. 2010 Jan-Feb;27(1):69-73. doi: 10.1111/j.1525-1470.2009.01060.x.

PMID:
20199415
48.

Treatment of Lyme borreliosis.

Girschick HJ, Morbach H, Tappe D.

Arthritis Res Ther. 2009;11(6):258. doi: 10.1186/ar2853. Epub 2009 Dec 17. Review.

49.

B-cell pathology in juvenile idiopathic arthritis.

Wiegering V, Girschick HJ, Morbach H.

Arthritis. 2010;2010:759868. doi: 10.1155/2010/759868. Epub 2010 Dec 2.

50.

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.

Humrich JY, Morbach H, Undeutsch R, Enghard P, Rosenberger S, Weigert O, Kloke L, Heimann J, Gaber T, Brandenburg S, Scheffold A, Huehn J, Radbruch A, Burmester GR, Riemekasten G.

Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):204-9. doi: 10.1073/pnas.0903158107. Epub 2009 Dec 14.

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