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Items: 35

1.

An Evolutionary Insight into Zika Virus Strains Isolated in the Latin American Region.

Simón D, Fajardo A, Moreno P, Moratorio G, Cristina J.

Viruses. 2018 Dec 8;10(12). pii: E698. doi: 10.3390/v10120698.

2.

Monitoring and redirecting virus evolution.

Moratorio G, Vignuzzi M.

PLoS Pathog. 2018 Jun 7;14(6):e1006979. doi: 10.1371/journal.ppat.1006979. eCollection 2018 Jun. No abstract available.

3.

Complete Genome Sequence of a Novel Recombinant Citrus Tristeza Virus, a Resistance-Breaking Isolate from Uruguay.

Benítez-Galeano MJ, Vallet T, Carrau L, Hernández-Rodríguez L, Bertalmío A, Rivas F, Rubio L, Maeso D, Vignuzzi M, Moratorio G, Colina R.

Genome Announc. 2018 May 31;6(22). pii: e00442-18. doi: 10.1128/genomeA.00442-18.

4.

Attenuation of RNA viruses by redirecting their evolution in sequence space.

Moratorio G, Henningsson R, Barbezange C, Carrau L, Bordería AV, Blanc H, Beaucourt S, Poirier EZ, Vallet T, Boussier J, Mounce BC, Fontes M, Vignuzzi M.

Nat Microbiol. 2017 Jun 5;2:17088. doi: 10.1038/nmicrobiol.2017.88.

PMID:
28581455
5.

Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses.

Mounce BC, Cesaro T, Moratorio G, Hooikaas PJ, Yakovleva A, Werneke SW, Smith EC, Poirier EZ, Simon-Loriere E, Prot M, Tamietti C, Vitry S, Volle R, Khou C, Frenkiel MP, Sakuntabhai A, Delpeyroux F, Pardigon N, Flamand M, Barba-Spaeth G, Lafon M, Denison MR, Albert ML, Vignuzzi M.

J Virol. 2016 Oct 14;90(21):9683-9692. Print 2016 Nov 1.

6.

A detailed comparative analysis of codon usage bias in Zika virus.

Cristina J, Fajardo A, Soñora M, Moratorio G, Musto H.

Virus Res. 2016 Sep 2;223:147-52. doi: 10.1016/j.virusres.2016.06.022. Epub 2016 Jul 19.

PMID:
27449601
7.

Naturally occurring NS3 resistance-associated variants in hepatitis C virus genotype 1: Their relevance for developing countries.

Echeverría N, Betancour G, Gámbaro F, Hernández N, López P, Chiodi D, Sánchez A, Boschi S, Fajardo A, Sóñora M, Moratorio G, Cristina J, Moreno P.

Virus Res. 2016 Sep 2;223:140-6. doi: 10.1016/j.virusres.2016.07.008. Epub 2016 Jul 19.

PMID:
27449600
8.

Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.

Mounce BC, Poirier EZ, Passoni G, Simon-Loriere E, Cesaro T, Prot M, Stapleford KA, Moratorio G, Sakuntabhai A, Levraud JP, Vignuzzi M.

Cell Host Microbe. 2016 Aug 10;20(2):167-77. doi: 10.1016/j.chom.2016.06.011. Epub 2016 Jul 14.

9.

Bayesian coalescent inference reveals high evolutionary rates and diversification of Zika virus populations.

Fajardo A, Soñora M, Moreno P, Moratorio G, Cristina J.

J Med Virol. 2016 Oct;88(10):1672-6. doi: 10.1002/jmv.24596. Epub 2016 Jun 20.

PMID:
27278855
10.

Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.

McDonald S, Block A, Beaucourt S, Moratorio G, Vignuzzi M, Peersen OB.

J Biol Chem. 2016 Jul 1;291(27):13999-4011. doi: 10.1074/jbc.M116.726596. Epub 2016 May 2.

11.

Whole-Genome Sequencing Analysis from the Chikungunya Virus Caribbean Outbreak Reveals Novel Evolutionary Genomic Elements.

Stapleford KA, Moratorio G, Henningsson R, Chen R, Matheus S, Enfissi A, Weissglas-Volkov D, Isakov O, Blanc H, Mounce BC, Dupont-Rouzeyrol M, Shomron N, Weaver S, Fontes M, Rousset D, Vignuzzi M.

PLoS Negl Trop Dis. 2016 Jan 25;10(1):e0004402. doi: 10.1371/journal.pntd.0004402. eCollection 2016 Jan.

12.

Low-Fidelity Polymerases of Alphaviruses Recombine at Higher Rates To Overproduce Defective Interfering Particles.

Poirier EZ, Mounce BC, Rozen-Gagnon K, Hooikaas PJ, Stapleford KA, Moratorio G, Vignuzzi M.

J Virol. 2015 Dec 16;90(5):2446-54. doi: 10.1128/JVI.02921-15.

13.

Group Selection and Contribution of Minority Variants during Virus Adaptation Determines Virus Fitness and Phenotype.

Bordería AV, Isakov O, Moratorio G, Henningsson R, Agüera-González S, Organtini L, Gnädig NF, Blanc H, Alcover A, Hafenstein S, Fontes M, Shomron N, Vignuzzi M.

PLoS Pathog. 2015 May 5;11(5):e1004838. doi: 10.1371/journal.ppat.1004838. eCollection 2015 May.

14.

Hepatitis C virus genetic variability and evolution.

Echeverría N, Moratorio G, Cristina J, Moreno P.

World J Hepatol. 2015 Apr 28;7(6):831-45. doi: 10.4254/wjh.v7.i6.831. Review.

15.

Phylogenetic analysis of the neuraminidase gene of pandemic H1N1 influenza A virus circulating in the South American region.

Comas V, Moratorio G, Soñora M, Goñi N, Pereyra S, Ifran S, Moreno P, Cristina J.

Virus Res. 2015 Feb 2;197:1-7. doi: 10.1016/j.virusres.2014.11.008. Epub 2014 Dec 3.

PMID:
25479596
16.

Genome-wide analysis of codon usage bias in Ebolavirus.

Cristina J, Moreno P, Moratorio G, Musto H.

Virus Res. 2015 Jan 22;196:87-93. doi: 10.1016/j.virusres.2014.11.005. Epub 2014 Nov 14.

PMID:
25445348
17.

Human endogenous retrovirus np9 gene is over expressed in chronic lymphocytic leukemia patients.

Fischer S, Echeverría N, Moratorio G, Landoni AI, Dighiero G, Cristina J, Oppezzo P, Moreno P.

Leuk Res Rep. 2014 Jul 25;3(2):70-2. doi: 10.1016/j.lrr.2014.06.005. eCollection 2014.

18.

A detailed molecular analysis of complete bovine leukemia virus genomes isolated from B-cell lymphosarcomas.

Moratorio G, Fischer S, Bianchi S, Tomé L, Rama G, Obal G, Carrión F, Pritsch O, Cristina J.

Vet Res. 2013 Mar 18;44:19. doi: 10.1186/1297-9716-44-19.

19.

A detailed comparative analysis on the overall codon usage patterns in West Nile virus.

Moratorio G, Iriarte A, Moreno P, Musto H, Cristina J.

Infect Genet Evol. 2013 Mar;14:396-400. doi: 10.1016/j.meegid.2013.01.001. Epub 2013 Jan 16.

PMID:
23333335
20.

Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development.

Goñi N, Iriarte A, Comas V, Soñora M, Moreno P, Moratorio G, Musto H, Cristina J.

Virol J. 2012 Nov 8;9:263. doi: 10.1186/1743-422X-9-263.

21.

Bayesian coalescent analysis of pandemic H1N1 influenza A virus circulating in the South American region.

Goñi N, Moratorio G, Coppola L, Ramas V, Comas V, Soñora M, Chiparelli H, Cristina J.

Virus Res. 2012 Dec;170(1-2):91-101. doi: 10.1016/j.virusres.2012.09.002. Epub 2012 Sep 13.

PMID:
22983300
22.

Analysis of human P[4]G2 rotavirus strains isolated in Brazil reveals codon usage bias and strong compositional constraints.

Gómez MM, Tort LF, Volotao Ede M, Recarey R, Moratorio G, Musto H, Leite JP, Cristina J.

Infect Genet Evol. 2011 Apr;11(3):580-6. doi: 10.1016/j.meegid.2011.01.006. Epub 2011 Jan 19.

23.

Genetic history of hepatitis C virus in Venezuela: high diversity and long time of evolution of HCV genotype 2.

Sulbarán MZ, Di Lello FA, Sulbarán Y, Cosson C, Loureiro CL, Rangel HR, Cantaloube JF, Campos RH, Moratorio G, Cristina J, Pujol FH.

PLoS One. 2010 Dec 13;5(12):e14315. doi: 10.1371/journal.pone.0014315.

24.

Evolution of dengue virus type 3 genotype III in Venezuela: diversification, rates and population dynamics.

Ramírez A, Fajardo A, Moros Z, Gerder M, Caraballo G, Camacho D, Comach G, Alarcón V, Zambrano J, Hernández R, Moratorio G, Cristina J, Liprandi F.

Virol J. 2010 Nov 18;7:329. doi: 10.1186/1743-422X-7-329.

25.

Phylogenetic analysis of pandemic 2009 influenza A virus circulating in the South American region: genetic relationships and vaccine strain match.

Goñi N, Moratorio G, Ramas V, Coppola L, Chiparelli H, Cristina J.

Arch Virol. 2011 Jan;156(1):87-94. doi: 10.1007/s00705-010-0825-7. Epub 2010 Oct 8.

PMID:
20931251
26.

Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes.

Moratorio G, Obal G, Dubra A, Correa A, Bianchi S, Buschiazzo A, Cristina J, Pritsch O.

Arch Virol. 2010 Apr;155(4):481-9. doi: 10.1007/s00705-010-0606-3. Epub 2010 Feb 19.

PMID:
20169372
27.

Phylogenetic analysis of human P[8]G9 rotavirus strains circulating in Brazil reveals the presence of a novel genetic variant.

Tort LF, Volotão Ede M, de Mendonça MC, da Silva MF, Siqueira AA, Assis RM, Moratorio G, Cristina J, Leite JP.

J Clin Virol. 2010 Apr;47(4):345-55. doi: 10.1016/j.jcv.2009.12.018. Epub 2010 Feb 4.

PMID:
20133185
28.

Modeling gene sequences over time in 2009 H1N1 influenza A virus populations.

Goñi N, Fajardo A, Moratorio G, Colina R, Cristina J.

Virol J. 2009 Dec 4;6:215. doi: 10.1186/1743-422X-6-215.

29.

Evidence of recombination in Hepatitis C Virus populations infecting a hemophiliac patient.

Moreno P, Alvarez M, López L, Moratorio G, Casane D, Castells M, Castro S, Cristina J, Colina R.

Virol J. 2009 Nov 18;6:203. doi: 10.1186/1743-422X-6-203.

30.

Phylogenetic analysis of the NS5 gene of dengue viruses isolated in Ecuador.

Regato M, Recarey R, Moratorio G, de Mora D, Garcia-Aguirre L, Gónzalez M, Mosquera C, Alava A, Fajardo A, Alvarez M, D' Andrea L, Dubra A, Martínez M, Khan B, Cristina J.

Virus Res. 2008 Mar;132(1-2):197-200. Epub 2007 Dec 11.

PMID:
18063164
31.

Bayesian coalescent inference of hepatitis A virus populations: evolutionary rates and patterns.

Moratorio G, Costa-Mattioli M, Piovani R, Romero H, Musto H, Cristina J.

J Gen Virol. 2007 Nov;88(Pt 11):3039-42.

PMID:
17947528
32.

Evolution of naturally occurring 5'non-coding region variants of Hepatitis C virus in human populations of the South American region.

Moratorio G, Martínez M, Gutiérrez MF, González K, Colina R, López-Tort F, López L, Recarey R, Schijman AG, Moreno MP, García-Aguirre L, Manascero AR, Cristina J.

Virol J. 2007 Aug 2;4:79.

33.

Hepatitis C virus genetic variability in patients undergoing antiviral therapy.

Cristina J, del Pilar Moreno M, Moratorio G.

Virus Res. 2007 Aug;127(2):185-94. Epub 2007 Apr 20. Review.

PMID:
17449128
34.

C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta-adrenergic pathway loci.

Wessel J, Moratorio G, Rao F, Mahata M, Zhang L, Greene W, Rana BK, Kennedy BP, Khandrika S, Huang P, Lillie EO, Shih PA, Smith DW, Wen G, Hamilton BA, Ziegler MG, Witztum JL, Schork NJ, Schmid-Schönbein GW, O'Connor DT.

J Hypertens. 2007 Feb;25(2):329-43.

PMID:
17211240
35.

Hepatitis C virus F protein sequence reveals a lack of functional constraints and a variable pattern of amino acid substitution.

Cristina J, Lopez F, Moratorio G, López L, Vasquez S, García-Aguirre L, Chunga A.

J Gen Virol. 2005 Jan;86(Pt 1):115-20.

PMID:
15604437

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