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Items: 1 to 50 of 96

1.

Functional screening for anti-CMV biologics identifies a broadly neutralizing epitope of an essential envelope protein.

Gardner TJ, Stein KR, Duty JA, Schwarz TM, Noriega VM, Kraus T, Moran TM, Tortorella D.

Nat Commun. 2016 Dec 14;7:13627. doi: 10.1038/ncomms13627.

2.

CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN.

Legarda D, Justus SJ, Ang RL, Rikhi N, Li W, Moran TM, Zhang J, Mizoguchi E, Zelic M, Kelliher MA, Blander JM, Ting AT.

Cell Rep. 2016 Jun 14;15(11):2449-61. doi: 10.1016/j.celrep.2016.05.032. Epub 2016 Jun 2.

3.

Perfluoroalkyl substance serum concentrations and immune response to FluMist vaccination among healthy adults.

Stein CR, Ge Y, Wolff MS, Ye X, Calafat AM, Kraus T, Moran TM.

Environ Res. 2016 Aug;149:171-178. doi: 10.1016/j.envres.2016.05.020. Epub 2016 May 18.

4.

Broadly neutralizing anti-influenza virus antibodies: enhancement of neutralizing potency in polyclonal mixtures and IgA backbones.

He W, Mullarkey CE, Duty JA, Moran TM, Palese P, Miller MS.

J Virol. 2015 Apr;89(7):3610-8. doi: 10.1128/JVI.03099-14. Epub 2015 Jan 14.

5.

Hit-and-run transcriptional control by bZIP1 mediates rapid nutrient signaling in Arabidopsis.

Para A, Li Y, Marshall-Colón A, Varala K, Francoeur NJ, Moran TM, Edwards MB, Hackley C, Bargmann BO, Birnbaum KD, McCombie WR, Krouk G, Coruzzi GM.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10371-6. doi: 10.1073/pnas.1404657111. Epub 2014 Jun 23.

6.

Human cytomegalovirus modulates monocyte-mediated innate immune responses during short-term experimental latency in vitro.

Noriega VM, Haye KK, Kraus TA, Kowalsky SR, Ge Y, Moran TM, Tortorella D.

J Virol. 2014 Aug;88(16):9391-405. doi: 10.1128/JVI.00934-14. Epub 2014 Jun 11.

7.

Polymorphisms in inflammatory genes are associated with term small for gestational age and preeclampsia.

Harmon QE, Engel SM, Wu MC, Moran TM, Luo J, Stuebe AM, Avery CL, Olshan AF.

Am J Reprod Immunol. 2014 May;71(5):472-84. doi: 10.1111/aji.12241. Epub 2014 Apr 4.

8.

Combinatorial cytokine code generates anti-viral state in dendritic cells.

Hartmann BM, Marjanovic N, Nudelman G, Moran TM, Sealfon SC.

Front Immunol. 2014 Feb 26;5:73. doi: 10.3389/fimmu.2014.00073. eCollection 2014.

9.

Plasma level of interferon γ induced protein 10 is a marker of sarcoidosis disease activity.

Geyer AI, Kraus T, Roberts M, Wisnivesky J, Eber CD, Hiensch R, Moran TM.

Cytokine. 2013 Oct;64(1):152-7. doi: 10.1016/j.cyto.2013.07.010. Epub 2013 Jul 27.

PMID:
23899720
10.

Mouse dendritic cell (DC) influenza virus infectivity is much lower than that for human DCs and is hemagglutinin subtype dependent.

Hartmann BM, Li W, Jia J, Patil S, Marjanovic N, Martínez-Romero C, Albrecht RA, Hayot F, García-Sastre A, Wetmur JG, Moran TM, Sealfon SC.

J Virol. 2013 Feb;87(3):1916-8. doi: 10.1128/JVI.02980-12. Epub 2012 Nov 28.

11.

Localized mucosal response to intranasal live attenuated influenza vaccine in adults.

Barría MI, Garrido JL, Stein C, Scher E, Ge Y, Engel SM, Kraus TA, Banach D, Moran TM.

J Infect Dis. 2013 Jan 1;207(1):115-24. doi: 10.1093/infdis/jis641. Epub 2012 Oct 19.

12.
13.

Estrogen mediates innate and adaptive immune alterations to influenza infection in pregnant mice.

Pazos MA, Kraus TA, Muñoz-Fontela C, Moran TM.

PLoS One. 2012;7(7):e40502. doi: 10.1371/journal.pone.0040502. Epub 2012 Jul 5.

14.

Granulocyte colony-stimulating factor protects mice during respiratory virus infections.

Hermesh T, Moran TM, Jain D, López CB.

PLoS One. 2012;7(5):e37334. doi: 10.1371/journal.pone.0037334. Epub 2012 May 16.

15.

A pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivo.

Tan GS, Krammer F, Eggink D, Kongchanagul A, Moran TM, Palese P.

J Virol. 2012 Jun;86(11):6179-88. doi: 10.1128/JVI.00469-12. Epub 2012 Apr 4.

16.

The influence of pregnancy on systemic immunity.

Pazos M, Sperling RS, Moran TM, Kraus TA.

Immunol Res. 2012 Dec;54(1-3):254-61. doi: 10.1007/s12026-012-8303-9. Review.

PMID:
22447351
17.

Immunogenicity of trivalent inactivated influenza vaccination received during pregnancy or postpartum.

Sperling RS, Engel SM, Wallenstein S, Kraus TA, Garrido J, Singh T, Kellerman L, Moran TM.

Obstet Gynecol. 2012 Mar;119(3):631-9. doi: 10.1097/AOG.0b013e318244ed20.

18.

High-throughput detection method for influenza virus.

Kumar P, Bartoszek AE, Moran TM, Gorski J, Bhattacharyya S, Navidad JF, Thakar MS, Malarkannan S.

J Vis Exp. 2012 Feb 4;(60). pii: 3623. doi: 10.3791/3623.

19.

Characterizing the pregnancy immune phenotype: results of the viral immunity and pregnancy (VIP) study.

Kraus TA, Engel SM, Sperling RS, Kellerman L, Lo Y, Wallenstein S, Escribese MM, Garrido JL, Singh T, Loubeau M, Moran TM.

J Clin Immunol. 2012 Apr;32(2):300-11. doi: 10.1007/s10875-011-9627-2. Epub 2011 Dec 24.

PMID:
22198680
20.

p53 serves as a host antiviral factor that enhances innate and adaptive immune responses to influenza A virus.

Muñoz-Fontela C, Pazos M, Delgado I, Murk W, Mungamuri SK, Lee SW, García-Sastre A, Moran TM, Aaronson SA.

J Immunol. 2011 Dec 15;187(12):6428-36. doi: 10.4049/jimmunol.1101459. Epub 2011 Nov 21.

21.

Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection.

Moltedo B, Li W, Yount JS, Moran TM.

PLoS Pathog. 2011 Nov;7(11):e1002345. doi: 10.1371/journal.ppat.1002345. Epub 2011 Nov 3.

22.

Buying time-the immune system determinants of the incubation period to respiratory viruses.

Hermesh T, Moltedo B, López CB, Moran TM.

Viruses. 2010 Nov;2(11):2541-58. doi: 10.3390/v2112541. Epub 2010 Nov 18.

23.

The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.

Cotter CR, Kim WK, Nguyen ML, Yount JS, López CB, Blaho JA, Moran TM.

J Virol. 2011 Dec;85(23):12662-72. doi: 10.1128/JVI.05557-11. Epub 2011 Sep 21.

24.

Alpha-defensins 1-3 release by dendritic cells is reduced by estrogen.

Escribese MM, Rodríguez-García M, Sperling R, Engel SM, Gallart T, Moran TM.

Reprod Biol Endocrinol. 2011 Aug 23;9:118. doi: 10.1186/1477-7827-9-118.

25.

Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes.

Wang TT, Tan GS, Hai R, Pica N, Ngai L, Ekiert DC, Wilson IA, García-Sastre A, Moran TM, Palese P.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18979-84. doi: 10.1073/pnas.1013387107. Epub 2010 Oct 18.

26.

Peripheral blood cytokine profiling during pregnancy and post-partum periods.

Kraus TA, Sperling RS, Engel SM, Lo Y, Kellerman L, Singh T, Loubeau M, Ge Y, Garrido JL, Rodríguez-García M, Moran TM.

Am J Reprod Immunol. 2010 Dec;64(6):411-26. doi: 10.1111/j.1600-0897.2010.00889.x. Epub 2010 Aug 16.

PMID:
20712812
27.

Palmitoylome profiling reveals S-palmitoylation-dependent antiviral activity of IFITM3.

Yount JS, Moltedo B, Yang YY, Charron G, Moran TM, López CB, Hang HC.

Nat Chem Biol. 2010 Aug;6(8):610-4. doi: 10.1038/nchembio.405. Epub 2010 Jul 4.

28.

Antiviral instruction of bone marrow leukocytes during respiratory viral infections.

Hermesh T, Moltedo B, Moran TM, López CB.

Cell Host Microbe. 2010 May 20;7(5):343-53. doi: 10.1016/j.chom.2010.04.006.

29.

Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins.

Wang TT, Tan GS, Hai R, Pica N, Petersen E, Moran TM, Palese P.

PLoS Pathog. 2010 Feb 26;6(2):e1000796. doi: 10.1371/journal.ppat.1000796.

30.

The virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells.

Cotter CR, Nguyen ML, Yount JS, López CB, Blaho JA, Moran TM.

PLoS One. 2010 Feb 18;5(2):e8684. doi: 10.1371/journal.pone.0008684.

31.

Immune response modeling of interferon beta-pretreated influenza virus-infected human dendritic cells.

Qiao L, Phipps-Yonas H, Hartmann B, Moran TM, Sealfon SC, Hayot F.

Biophys J. 2010 Feb 17;98(4):505-14. doi: 10.1016/j.bpj.2009.10.049.

32.

Hemagglutinin-pseudotyped green fluorescent protein-expressing influenza viruses for the detection of influenza virus neutralizing antibodies.

Martínez-Sobrido L, Cadagan R, Steel J, Basler CF, Palese P, Moran TM, García-Sastre A.

J Virol. 2010 Feb;84(4):2157-63. doi: 10.1128/JVI.01433-09. Epub 2009 Nov 25.

33.

IL-11 regulates autoimmune demyelination.

Gurfein BT, Zhang Y, López CB, Argaw AT, Zameer A, Moran TM, John GR.

J Immunol. 2009 Oct 1;183(7):4229-40. doi: 10.4049/jimmunol.0900622. Epub 2009 Sep 4.

34.

The functional impairment of natural killer cells during influenza virus infection.

Guo H, Kumar P, Moran TM, Garcia-Sastre A, Zhou Y, Malarkannan S.

Immunol Cell Biol. 2009 Nov-Dec;87(8):579-89. doi: 10.1038/icb.2009.60. Epub 2009 Sep 1.

35.

Cutting edge: stealth influenza virus replication precedes the initiation of adaptive immunity.

Moltedo B, López CB, Pazos M, Becker MI, Hermesh T, Moran TM.

J Immunol. 2009 Sep 15;183(6):3569-73. doi: 10.4049/jimmunol.0900091. Epub 2009 Aug 28.

36.

Alpha-C-galactosylceramide as an adjuvant for a live attenuated influenza virus vaccine.

Kopecky-Bromberg SA, Fraser KA, Pica N, Carnero E, Moran TM, Franck RW, Tsuji M, Palese P.

Vaccine. 2009 Jun 8;27(28):3766-74. doi: 10.1016/j.vaccine.2009.03.090. Epub 2009 Apr 23.

37.

Impact of alpha-defensins1-3 on the maturation and differentiation of human monocyte-derived DCs. Concentration-dependent opposite dual effects.

Rodríguez-García M, Oliva H, Climent N, Escribese MM, García F, Moran TM, Gatell JM, Gallart T.

Clin Immunol. 2009 Jun;131(3):374-84. doi: 10.1016/j.clim.2009.01.012. Epub 2009 Feb 23.

PMID:
19237318
38.

Antiviral-activated dendritic cells: a paracrine-induced response state.

Bordería AV, Hartmann BM, Fernandez-Sesma A, Moran TM, Sealfon SC.

J Immunol. 2008 Nov 15;181(10):6872-6881.

39.

Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus.

Phipps-Yonas H, Seto J, Sealfon SC, Moran TM, Fernandez-Sesma A.

PLoS Pathog. 2008 Oct;4(10):e1000193. doi: 10.1371/journal.ppat.1000193. Epub 2008 Oct 31.

40.

Estrogen inhibits dendritic cell maturation to RNA viruses.

Escribese MM, Kraus T, Rhee E, Fernandez-Sesma A, López CB, Moran TM.

Blood. 2008 Dec 1;112(12):4574-84. doi: 10.1182/blood-2008-04-148692. Epub 2008 Sep 18.

41.

A comprehensive evaluation of human plasmacytoid dendritic cells using small volumes of human blood.

Phipps-Yonas H, Jiang K, Hartmann BM, Ge Y, Sealfon SC, Moran TM.

J Interferon Cytokine Res. 2008 Aug;28(8):501-7. doi: 10.1089/jir.2008.0014.

PMID:
18729740
42.

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.

Friedman CS, O'Donnell MA, Legarda-Addison D, Ng A, Cárdenas WB, Yount JS, Moran TM, Basler CF, Komuro A, Horvath CM, Xavier R, Ting AT.

EMBO Rep. 2008 Sep;9(9):930-6. doi: 10.1038/embor.2008.136. Epub 2008 Jul 18.

44.

A prospective, comparative study of the immune response to inactivated influenza vaccine in pediatric liver transplant recipients and their healthy siblings.

Madan RP, Tan M, Fernandez-Sesma A, Moran TM, Emre S, Campbell A, Herold BC.

Clin Infect Dis. 2008 Mar 1;46(5):712-8. doi: 10.1086/527391.

45.

Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells.

Hu J, Sealfon SC, Hayot F, Jayaprakash C, Kumar M, Pendleton AC, Ganee A, Fernandez-Sesma A, Moran TM, Wetmur JG.

Nucleic Acids Res. 2007;35(15):5232-41. Epub 2007 Aug 2.

46.

Cytokine-independent upregulation of MDA5 in viral infection.

Yount JS, Moran TM, López CB.

J Virol. 2007 Jul;81(13):7316-9. Epub 2007 May 2. Erratum in: J Virol. 2007 Sep;81(17):9609.

47.

A novel model of demyelinating encephalomyelitis induced by monocytes and dendritic cells.

Furtado GC, Piña B, Tacke F, Gaupp S, van Rooijen N, Moran TM, Randolph GJ, Ransohoff RM, Chensue SW, Raine CS, Lira SA.

J Immunol. 2006 Nov 15;177(10):6871-9.

48.

A novel role for viral-defective interfering particles in enhancing dendritic cell maturation.

Yount JS, Kraus TA, Horvath CM, Moran TM, López CB.

J Immunol. 2006 Oct 1;177(7):4503-13.

49.

Influenza virus evades innate and adaptive immunity via the NS1 protein.

Fernandez-Sesma A, Marukian S, Ebersole BJ, Kaminski D, Park MS, Yuen T, Sealfon SC, García-Sastre A, Moran TM.

J Virol. 2006 Jul;80(13):6295-304.

50.

Sendai virus infection induces efficient adaptive immunity independently of type I interferons.

López CB, Yount JS, Hermesh T, Moran TM.

J Virol. 2006 May;80(9):4538-45.

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