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Items: 1 to 50 of 107

1.

Pathological Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma.

Xu Y, Taylor P, Andrade J, Ueberheide B, Shuch B, Glazer PM, Bindra RS, Moran MF, Linehan WM, Neel BG.

Cancer Res. 2018 Oct 8. pii: canres.0901.2018. doi: 10.1158/0008-5472.CAN-18-0901. [Epub ahead of print]

PMID:
30297534
2.

Refined RIP-seq protocol for epitranscriptome analysis with low input materials.

Zeng Y, Wang S, Gao S, Soares F, Ahmed M, Guo H, Wang M, Hua JT, Guan J, Moran MF, Tsao MS, He HH.

PLoS Biol. 2018 Sep 13;16(9):e2006092. doi: 10.1371/journal.pbio.2006092. eCollection 2018 Sep.

3.

A feed forward loop enforces YAP/TAZ signaling during tumorigenesis.

Gill MK, Christova T, Zhang YY, Gregorieff A, Zhang L, Narimatsu M, Song S, Xiong S, Couzens AL, Tong J, Krieger JR, Moran MF, Zlotta AR, van der Kwast TH, Gingras AC, Sicheri F, Wrana JL, Attisano L.

Nat Commun. 2018 Aug 29;9(1):3510. doi: 10.1038/s41467-018-05939-2.

4.

Reliability of Smartphone Inclinometry to Measure Upper Cervical Range of Motion.

Ullucci PA Jr, Tudini F, Moran MF.

J Sport Rehabil. 2018 Jul 24:1-12. doi: 10.1123/jsr.2018-0048. [Epub ahead of print]

PMID:
30040023
5.

Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis.

Wang S, Juan J, Zhang Z, Du Y, Xu Y, Tong J, Cao B, Moran MF, Zeng Y, Mao X.

Cell Death Dis. 2017 Sep 21;8(9):e3058. doi: 10.1038/cddis.2017.450.

6.

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation.

Xie JL, Qin L, Miao Z, Grys BT, Diaz JC, Ting K, Krieger JR, Tong J, Tan K, Leach MD, Ketela T, Moran MF, Krysan DJ, Boone C, Andrews BJ, Selmecki A, Ho Wong K, Robbins N, Cowen LE.

Nat Commun. 2017 Sep 11;8(1):499. doi: 10.1038/s41467-017-00547-y.

7.

A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.

Feinberg K, Kolaj A, Wu C, Grinshtein N, Krieger JR, Moran MF, Rubin LL, Miller FD, Kaplan DR.

J Cell Biol. 2017 Nov 6;216(11):3655-3675. doi: 10.1083/jcb.201705085. Epub 2017 Sep 6.

8.

The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis.

Xu Y, Zhang Z, Li J, Tong J, Cao B, Taylor P, Tang X, Wu D, Moran MF, Zeng Y, Mao X.

J Hematol Oncol. 2017 Jul 3;10(1):132. doi: 10.1186/s13045-017-0499-7.

9.

Impact of Direction of Unloading Influence on Template Rate of Perceived Exertion.

Greer BK, Young PR, Thompson B, Rickert BJ, Moran MF.

J Strength Cond Res. 2017 Mar 23. doi: 10.1519/JSC.0000000000001846. [Epub ahead of print]

PMID:
28346316
10.

CCM-3 Promotes C. elegans Germline Development by Regulating Vesicle Trafficking Cytokinesis and Polarity.

Pal S, Lant B, Yu B, Tian R, Tong J, Krieger JR, Moran MF, Gingras AC, Derry WB.

Curr Biol. 2017 Mar 20;27(6):868-876. doi: 10.1016/j.cub.2017.02.028. Epub 2017 Mar 9.

11.

Does positive pressure body weight-support alter spatiotemporal gait parameters in healthy and parkinsonian individuals?

Lander JJ, Moran MF.

NeuroRehabilitation. 2017;40(2):271-276. doi: 10.3233/NRE-161412.

PMID:
28222548
12.

Integrated analysis of proteome, phosphotyrosine-proteome, tyrosine-kinome, and tyrosine-phosphatome in acute myeloid leukemia.

Tong J, Helmy M, Cavalli FM, Jin L, St-Germain J, Karisch R, Taylor P, Minden MD, Taylor MD, Neel BG, Bader GD, Moran MF.

Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600361.

13.

Protein-phosphotyrosine proteome profiling by superbinder-SH2 domain affinity purification mass spectrometry, sSH2-AP-MS.

Tong J, Cao B, Martyn GD, Krieger JR, Taylor P, Yates B, Sidhu SS, Li SS, Mao X, Moran MF.

Proteomics. 2017 Mar;17(6). doi: 10.1002/pmic.201600360. Epub 2017 Jan 17.

PMID:
27880036
14.

Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.

Matsumoto Y, La Rose J, Kent OA, Wagner MJ, Narimatsu M, Levy AD, Omar MH, Tong J, Krieger JR, Riggs E, Storozhuk Y, Pasquale J, Ventura M, Yeganeh B, Post M, Moran MF, Grynpas MD, Wrana JL, Superti-Furga G, Koleske AJ, Pendergast AM, Rottapel R.

J Clin Invest. 2016 Dec 1;126(12):4482-4496. doi: 10.1172/JCI87802. Epub 2016 Oct 31.

15.

Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.

Wang D, Pham NA, Tong J, Sakashita S, Allo G, Kim L, Yanagawa N, Raghavan V, Wei Y, To C, Trinh QM, Starmans MH, Chan-Seng-Yue MA, Chadwick D, Li L, Zhu CQ, Liu N, Li M, Lee S, Ignatchenko V, Strumpf D, Taylor P, Moghal N, Liu G, Boutros PC, Kislinger T, Pintilie M, Jurisica I, Shepherd FA, McPherson JD, Muthuswamy L, Moran MF, Tsao MS.

Int J Cancer. 2017 Feb 1;140(3):662-673. doi: 10.1002/ijc.30472. Epub 2016 Nov 7.

16.

Tibial Acceleration and Spatiotemporal Mechanics in Distance Runners During Reduced-Body-Weight Conditions.

Moran MF, Rickert BJ, Greer BK.

J Sport Rehabil. 2017 May;26(3):221-226. doi: 10.1123/jsr.2015-0141. Epub 2016 Aug 24.

PMID:
27632877
17.

Cellular stress induces TRB3/USP9x-dependent Notch activation in cancer.

Izrailit J, Jaiswal A, Zheng W, Moran MF, Reedijk M.

Oncogene. 2017 Feb 23;36(8):1048-1057. doi: 10.1038/onc.2016.276. Epub 2016 Sep 5.

PMID:
27593927
18.

Identification of human plasma cells with a lamprey monoclonal antibody.

Yu C, Liu Y, Chan JT, Tong J, Li Z, Shi M, Davani D, Parsons M, Khan S, Zhan W, Kyu S, Grunebaum E, Campisi P, Propst EJ, Jaye DL, Trudel S, Moran MF, Ostrowski M, Herrin BR, Lee FE, Sanz I, Cooper MD, Ehrhardt GR.

JCI Insight. 2016;1(3). pii: e84738. Epub 2016 Mar 17.

19.

The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice.

Zhang Z, Tong J, Tang X, Juan J, Cao B, Hurren R, Chen G, Taylor P, Xu X, Shi CX, Du J, Hou J, Wang G, Wu D, Stewart AK, Schimmer AD, Moran MF, Mao X.

Blood. 2016 Mar 31;127(13):1676-86. doi: 10.1182/blood-2015-07-658203. Epub 2016 Jan 29.

20.

Distinct Regulation of Transmitter Release at the Drosophila NMJ by Different Isoforms of nemy.

Knight D, Iliadi KG, Iliadi N, Wilk R, Hu J, Krause HM, Taylor P, Moran MF, Boulianne GL.

PLoS One. 2015 Aug 3;10(8):e0132548. doi: 10.1371/journal.pone.0132548. eCollection 2015.

21.

CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration.

Wei Y, Vellanki RN, Coyaud É, Ignatchenko V, Li L, Krieger JR, Taylor P, Tong J, Pham NA, Liu G, Raught B, Wouters BG, Kislinger T, Tsao MS, Moran MF.

Mol Cancer Res. 2015 Jul;13(7):1119-29. doi: 10.1158/1541-7786.MCR-14-0165-T. Epub 2015 Mar 17.

22.

Comprehensive proteome analysis of fresh frozen and optimal cutting temperature (OCT) embedded primary non-small cell lung carcinoma by LC-MS/MS.

Zhang W, Sakashita S, Taylor P, Tsao MS, Moran MF.

Methods. 2015 Jun 15;81:50-5. doi: 10.1016/j.ymeth.2015.02.008. Epub 2015 Feb 23.

PMID:
25721092
23.

Signal transduction.

Pandey A, Moran MF.

Proteomics. 2015 Jan;15(2-3):179-82. doi: 10.1002/pmic.201570023. No abstract available.

PMID:
25588725
24.

Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity.

Jin LL, Wybenga-Groot LE, Tong J, Taylor P, Minden MD, Trudel S, McGlade CJ, Moran MF.

Mol Cell Proteomics. 2015 Mar;14(3):695-706. doi: 10.1074/mcp.M114.044404. Epub 2015 Jan 13.

25.

Ubiquitination of the transcription factor c-MAF is mediated by multiple lysine residues.

Chen G, Xu X, Tong J, Han K, Zhang Z, Tang J, Li S, Yang C, Li J, Cao B, Zhou H, Wu D, Moran MF, Mao X.

Int J Biochem Cell Biol. 2014 Dec;57:157-66. doi: 10.1016/j.biocel.2014.10.024. Epub 2014 Oct 30.

PMID:
25448412
26.

Integrated omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact.

Li L, Wei Y, To C, Zhu CQ, Tong J, Pham NA, Taylor P, Ignatchenko V, Ignatchenko A, Zhang W, Wang D, Yanagawa N, Li M, Pintilie M, Liu G, Muthuswamy L, Shepherd FA, Tsao MS, Kislinger T, Moran MF.

Nat Commun. 2014 Nov 28;5:5469. doi: 10.1038/ncomms6469.

PMID:
25429762
27.

Comprehensive identification of phosphorylation sites on the Numb endocytic adaptor protein.

Krieger JR, Taylor P, Moran MF, McGlade CJ.

Proteomics. 2015 Jan;15(2-3):434-46. doi: 10.1002/pmic.201400232.

PMID:
25403733
28.

The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation.

Pasyk S, Molinski S, Ahmadi S, Ramjeesingh M, Huan LJ, Chin S, Du K, Yeger H, Taylor P, Moran MF, Bear CE.

Proteomics. 2015 Jan;15(2-3):447-61. doi: 10.1002/pmic.201400218. Epub 2014 Dec 17.

PMID:
25330774
29.

Differential regulation of FGFR3 by PTPN1 and PTPN2.

St-Germain JR, Taylor P, Zhang W, Li Z, Ketela T, Moffat J, Neel BG, Trudel S, Moran MF.

Proteomics. 2015 Jan;15(2-3):419-33. doi: 10.1002/pmic.201400259. Epub 2014 Dec 17.

30.

Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity.

Persaud A, Alberts P, Mari S, Tong J, Murchie R, Maspero E, Safi F, Moran MF, Polo S, Rotin D.

Sci Signal. 2014 Oct 7;7(346):ra95. doi: 10.1126/scisignal.2005290.

PMID:
25292214
31.
32.

Proteomic profiles of human lung adeno and squamous cell carcinoma using super-SILAC and label-free quantification approaches.

Zhang W, Wei Y, Ignatchenko V, Li L, Sakashita S, Pham NA, Taylor P, Tsao MS, Kislinger T, Moran MF.

Proteomics. 2014 Mar;14(6):795-803. doi: 10.1002/pmic.201300382.

PMID:
24453208
33.

The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor.

Wills MK, Tong J, Tremblay SL, Moran MF, Jones N.

Mol Biol Cell. 2014 Mar;25(6):739-52. doi: 10.1091/mbc.E13-08-0434. Epub 2014 Jan 15.

34.

Odin (ANKS1A) modulates EGF receptor recycling and stability.

Tong J, Sydorskyy Y, St-Germain JR, Taylor P, Tsao MS, Moran MF.

PLoS One. 2013 Jun 25;8(6):e64817. doi: 10.1371/journal.pone.0064817. Print 2013.

35.

Gait analysis of teenagers and young adults diagnosed with autism and severe verbal communication disorders.

Weiss MJ, Moran MF, Parker ME, Foley JT.

Front Integr Neurosci. 2013 May 20;7:33. doi: 10.3389/fnint.2013.00033. eCollection 2013.

36.

A phosphoproteomics approach to identify candidate kinase inhibitor pathway targets in lymphoma-like primary cell lines.

Vojvodic M, Hansford LM, Morozova O, Blakely KM, Taylor P, Fathers KE, Moffat J, Marra M, Smith KM, Moran MF, Kaplan DR.

Curr Drug Discov Technol. 2013 Dec;10(4):283-304.

PMID:
23701117
37.

Two-legged hopping in autism spectrum disorders.

Moran MF, Foley JT, Parker ME, Weiss MJ.

Front Integr Neurosci. 2013 Mar 26;7:14. doi: 10.3389/fnint.2013.00014. eCollection 2013.

38.

A strategy for modulation of enzymes in the ubiquitin system.

Ernst A, Avvakumov G, Tong J, Fan Y, Zhao Y, Alberts P, Persaud A, Walker JR, Neculai AM, Neculai D, Vorobyov A, Garg P, Beatty L, Chan PK, Juang YC, Landry MC, Yeh C, Zeqiraj E, Karamboulas K, Allali-Hassani A, Vedadi M, Tyers M, Moffat J, Sicheri F, Pelletier L, Durocher D, Raught B, Rotin D, Yang J, Moran MF, Dhe-Paganon S, Sidhu SS.

Science. 2013 Feb 1;339(6119):590-5. doi: 10.1126/science.1230161. Epub 2013 Jan 3.

39.

Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb.

Krieger JR, Taylor P, Gajadhar AS, Guha A, Moran MF, McGlade CJ.

Mol Cell Proteomics. 2013 Feb;12(2):499-514. doi: 10.1074/mcp.M112.020768. Epub 2012 Dec 4.

40.

Purification and identification of cell surface antigens using lamprey monoclonal antibodies.

Yu C, Ali S, St-Germain J, Liu Y, Yu X, Jaye DL, Moran MF, Cooper MD, Ehrhardt GR.

J Immunol Methods. 2012 Dec 14;386(1-2):43-9. doi: 10.1016/j.jim.2012.08.016. Epub 2012 Sep 4.

41.

Proteomic profiling of the planarian Schmidtea mediterranea and its mucous reveals similarities with human secretions and those predicted for parasitic flatworms.

Bocchinfuso DG, Taylor P, Ross E, Ignatchenko A, Ignatchenko V, Kislinger T, Pearson BJ, Moran MF.

Mol Cell Proteomics. 2012 Sep;11(9):681-91. doi: 10.1074/mcp.M112.019026. Epub 2012 May 31.

42.

Selected Reaction Monitoring (SRM) Analysis of Epidermal Growth Factor Receptor (EGFR) in Formalin Fixed Tumor Tissue.

Hembrough T, Thyparambil S, Liao WL, Darfler MM, Abdo J, Bengali KM, Taylor P, Tong J, Lara-Guerra H, Waddell TK, Moran MF, Tsao MS, Krizman DB, Burrows J.

Clin Proteomics. 2012 May 3;9(1):5. doi: 10.1186/1559-0275-9-5.

43.

The human phosphotyrosine signaling network: evolution and hotspots of hijacking in cancer.

Li L, Tibiche C, Fu C, Kaneko T, Moran MF, Schiller MR, Li SS, Wang E.

Genome Res. 2012 Jul;22(7):1222-30. doi: 10.1101/gr.128819.111. Epub 2011 Dec 22.

44.

Global proteomic assessment of the classical protein-tyrosine phosphatome and "Redoxome".

Karisch R, Fernandez M, Taylor P, Virtanen C, St-Germain JR, Jin LL, Harris IS, Mori J, Mak TW, Senis YA, Östman A, Moran MF, Neel BG.

Cell. 2011 Sep 2;146(5):826-40. doi: 10.1016/j.cell.2011.07.020.

45.

Quantitative phospho-proteomic profiling of hepatocyte growth factor (HGF)-MET signaling in colorectal cancer.

Organ SL, Tong J, Taylor P, St-Germain JR, Navab R, Moran MF, Tsao MS.

J Proteome Res. 2011 Jul 1;10(7):3200-11. doi: 10.1021/pr200238t. Epub 2011 Jun 9.

PMID:
21609022
46.

A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway.

Mao X, Cao B, Wood TE, Hurren R, Tong J, Wang X, Wang W, Li J, Jin Y, Sun W, Spagnuolo PA, MacLean N, Moran MF, Datti A, Wrana J, Batey RA, Schimmer AD.

Blood. 2011 Feb 10;117(6):1986-97. doi: 10.1182/blood-2010-05-284810. Epub 2010 Dec 6.

47.

Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures.

Wei Y, Tong J, Taylor P, Strumpf D, Ignatchenko V, Pham NA, Yanagawa N, Liu G, Jurisica I, Shepherd FA, Tsao MS, Kislinger T, Moran MF.

J Proteome Res. 2011 Jan 7;10(1):161-74. doi: 10.1021/pr100491e. Epub 2010 Sep 24.

PMID:
20815376
48.

System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma.

Morozova O, Vojvodic M, Grinshtein N, Hansford LM, Blakely KM, Maslova A, Hirst M, Cezard T, Morin RD, Moore R, Smith KM, Miller F, Taylor P, Thiessen N, Varhol R, Zhao Y, Jones S, Moffat J, Kislinger T, Moran MF, Kaplan DR, Marra MA.

Clin Cancer Res. 2010 Sep 15;16(18):4572-82. doi: 10.1158/1078-0432.CCR-10-0627. Epub 2010 Jul 22. Erratum in: Clin Cancer Res. 2010 Dec 1;16(23):5914.

49.

Measurement of protein phosphorylation stoichiometry by selected reaction monitoring mass spectrometry.

Jin LL, Tong J, Prakash A, Peterman SM, St-Germain JR, Taylor P, Trudel S, Moran MF.

J Proteome Res. 2010 May 7;9(5):2752-61. doi: 10.1021/pr100024a.

PMID:
20205385
50.

Multiple myeloma phosphotyrosine proteomic profile associated with FGFR3 expression, ligand activation, and drug inhibition.

St-Germain JR, Taylor P, Tong J, Jin LL, Nikolic A, Stewart II, Ewing RM, Dharsee M, Li Z, Trudel S, Moran MF.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):20127-32. doi: 10.1073/pnas.0910957106. Epub 2009 Nov 9.

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