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Items: 21

1.

Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics.

Storck EM, Morales-Sanfrutos J, Serwa RA, Panyain N, Lanyon-Hogg T, Tolmachova T, Ventimiglia LN, Martin-Serrano J, Seabra MC, Wojciak-Stothard B, Tate EW.

Nat Chem. 2019 Jun;11(6):552-561. doi: 10.1038/s41557-019-0237-6. Epub 2019 Apr 1.

2.

Whole Proteome Profiling of N-Myristoyltransferase Activity and Inhibition Using Sortase A.

Goya Grocin A, Serwa RA, Morales Sanfrutos J, Ritzefeld M, Tate EW.

Mol Cell Proteomics. 2019 Jan;18(1):115-126. doi: 10.1074/mcp.RA118.001043. Epub 2018 Oct 19.

3.

Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus.

Mousnier A, Bell AS, Swieboda DP, Morales-Sanfrutos J, Pérez-Dorado I, Brannigan JA, Newman J, Ritzefeld M, Hutton JA, Guedán A, Asfor AS, Robinson SW, Hopkins-Navratilova I, Wilkinson AJ, Johnston SL, Leatherbarrow RJ, Tuthill TJ, Solari R, Tate EW.

Nat Chem. 2018 Jun;10(6):599-606. doi: 10.1038/s41557-018-0039-2. Epub 2018 May 14.

4.

Development of a Photo-Cross-Linkable Diaminoquinazoline Inhibitor for Target Identification in Plasmodium falciparum.

Lubin AS, Rueda-Zubiaurre A, Matthews H, Baumann H, Fisher FR, Morales-Sanfrutos J, Hadavizadeh KS, Nardella F, Tate EW, Baum J, Scherf A, Fuchter MJ.

ACS Infect Dis. 2018 Apr 13;4(4):523-530. doi: 10.1021/acsinfecdis.7b00228. Epub 2018 Feb 5.

5.

Mouse Stbd1 is N-myristoylated and affects ER-mitochondria association and mitochondrial morphology.

Demetriadou A, Morales-Sanfrutos J, Nearchou M, Baba O, Kyriacou K, Tate EW, Drousiotou A, Petrou PP.

J Cell Sci. 2017 Mar 1;130(5):903-915. doi: 10.1242/jcs.195263. Epub 2017 Jan 30.

6.

N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells.

Thinon E, Morales-Sanfrutos J, Mann DJ, Tate EW.

ACS Chem Biol. 2016 Aug 19;11(8):2165-76. doi: 10.1021/acschembio.6b00371. Epub 2016 Jun 7.

7.

Divinyl sulfone cross-linked cyclodextrin-based polymeric materials: synthesis and applications as sorbents and encapsulating agents.

Morales-Sanfrutos J, Lopez-Jaramillo FJ, Elremaily MA, Hernández-Mateo F, Santoyo-Gonzalez F.

Molecules. 2015 Feb 19;20(3):3565-81. doi: 10.3390/molecules20033565.

8.

Bicyclic peptides conjugated to an albumin-binding tag diffuse efficiently into solid tumors.

Pollaro L, Raghunathan S, Morales-Sanfrutos J, Angelini A, Kontos S, Heinis C.

Mol Cancer Ther. 2015 Jan;14(1):151-61. doi: 10.1158/1535-7163.MCT-14-0534. Epub 2014 Nov 7.

9.

Bicyclic peptide ligands pulled out of cysteine-rich peptide libraries.

Chen S, Rentero Rebollo I, Buth SA, Morales-Sanfrutos J, Touati J, Leiman PG, Heinis C.

J Am Chem Soc. 2013 May 1;135(17):6562-9. doi: 10.1021/ja400461h. Epub 2013 Apr 17.

PMID:
23560397
10.

Functionalization of immunostimulating complexes (ISCOMs) with lipid vinyl sulfones and their application in immunological techniques and therapy.

Cruz-Bustos T, González-González G, Morales-Sanfrutos J, Megía-Fernández A, Santoyo-González F, Osuna A.

Int J Nanomedicine. 2012;7:5941-56. doi: 10.2147/IJN.S35556. Epub 2012 Dec 3.

11.

Electrochemiluminescent disposable cholesterol biosensor based on avidin-biotin assembling with the electroformed luminescent conducting polymer poly(luminol-biotinylated pyrrole).

Ballesta-Claver J, Ametis-Cabello J, Morales-Sanfrutos J, Megía-Fernández A, Valencia-Mirón MC, Santoyo-González F, Capitán-Vallvey LF.

Anal Chim Acta. 2012 Nov 19;754:91-8. doi: 10.1016/j.aca.2012.10.006. Epub 2012 Oct 11.

PMID:
23140959
12.

Bicyclization and tethering to albumin yields long-acting peptide antagonists.

Angelini A, Morales-Sanfrutos J, Diderich P, Chen S, Heinis C.

J Med Chem. 2012 Nov 26;55(22):10187-97. doi: 10.1021/jm301276e. Epub 2012 Nov 5.

PMID:
23088498
13.

Chemical macrocyclization of peptides fused to antibody Fc fragments.

Angelini A, Diderich P, Morales-Sanfrutos J, Thurnheer S, Hacker D, Menin L, Heinis C.

Bioconjug Chem. 2012 Sep 19;23(9):1856-63. Epub 2012 Aug 10.

PMID:
22812498
14.

Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides.

Chen S, Morales-Sanfrutos J, Angelini A, Cutting B, Heinis C.

Chembiochem. 2012 May 7;13(7):1032-8. doi: 10.1002/cbic.201200049. Epub 2012 Apr 11.

PMID:
22492661
15.

Alkyl sulfonyl derivatized PAMAM-G2 dendrimers as nonviral gene delivery vectors with improved transfection efficiencies.

Morales-Sanfrutos J, Megia-Fernandez A, Hernandez-Mateo F, Giron-Gonzalez MD, Salto-Gonzalez R, Santoyo-Gonzalez F.

Org Biomol Chem. 2011 Feb 7;9(3):851-64. doi: 10.1039/c0ob00355g. Epub 2010 Nov 30.

PMID:
21120228
16.

Vinyl sulfone bifunctional tag reagents for single-point modification of proteins.

Morales-Sanfrutos J, Lopez-Jaramillo FJ, Hernandez-Mateo F, Santoyo-Gonzalez F.

J Org Chem. 2010 Jun 18;75(12):4039-47. doi: 10.1021/jo100324p.

PMID:
20496947
17.

Vinyl sulfone: a versatile function for simple bioconjugation and immobilization.

Morales-Sanfrutos J, Lopez-Jaramillo J, Ortega-Muñoz M, Megia-Fernandez A, Perez-Balderas F, Hernandez-Mateo F, Santoyo-Gonzalez F.

Org Biomol Chem. 2010 Feb 7;8(3):667-75. doi: 10.1039/b920576d. Epub 2009 Dec 11.

PMID:
20090986
18.

Synthesis of molecular nanocages by click chemistry.

Morales-Sanfrutos J, Ortega-Muñoz M, Lopez-Jaramillo J, Hernandez-Mateo F, Santoyo-Gonzalez F.

J Org Chem. 2008 Oct 3;73(19):7772-4. doi: 10.1021/jo801324x. Epub 2008 Sep 4.

PMID:
18767810
19.

Synthesis of calixarene-based cavitands and nanotubes by click chemistry.

Morales-Sanfrutos J, Ortega-Muñoz M, Lopez-Jaramillo J, Hernandez-Mateo F, Santoyo-Gonzalez F.

J Org Chem. 2008 Oct 3;73(19):7768-71. doi: 10.1021/jo801325c. Epub 2008 Aug 22.

PMID:
18722401
20.

Click multivalent neoglycoconjugates as synthetic activators in cell adhesion and stimulation of monocyte/machrophage cell lines.

Ortega-Muñoz M, Morales-Sanfrutos J, Perez-Balderas F, Hernandez-Mateo F, Giron-Gonzalez MD, Sevillano-Tripero N, Salto-Gonzalez R, Santoyo-Gonzalez F.

Org Biomol Chem. 2007 Jul 21;5(14):2291-301. Epub 2007 Jun 13.

PMID:
17609761
21.

Multivalent neoglycoconjugates by regiospecific cycloaddition of alkynes and azides using organic-soluble copper catalysts.

Pérez-Balderas F, Ortega-Muñoz M, Morales-Sanfrutos J, Hernández-Mateo F, Calvo-Flores FG, Calvo-Asín JA, Isac-García J, Santoyo-González F.

Org Lett. 2003 May 29;5(11):1951-4.

PMID:
12762694

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