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Items: 1 to 50 of 85

1.

Cerium oxide nanoparticles improve liver regeneration after acetaminophen-induced liver injury and partial hepatectomy in rats.

Córdoba-Jover B, Arce-Cerezo A, Ribera J, Pauta M, Oró D, Casals G, Fernández-Varo G, Casals E, Puntes V, Jiménez W, Morales-Ruiz M.

J Nanobiotechnology. 2019 Oct 31;17(1):112. doi: 10.1186/s12951-019-0544-5.

2.

Cerium oxide nanoparticles display antilipogenic effect in rats with non-alcoholic fatty liver disease.

Carvajal S, Perramón M, Oró D, Casals E, Fernández-Varo G, Casals G, Parra M, González de la Presa B, Ribera J, Pastor Ó, Morales-Ruíz M, Puntes V, Jiménez W.

Sci Rep. 2019 Sep 6;9(1):12848. doi: 10.1038/s41598-019-49262-2.

3.

Beyond the Scavenging of Reactive Oxygen Species (ROS): Direct Effect of Cerium Oxide Nanoparticles in Reducing Fatty Acids Content in an In Vitro Model of Hepatocellular Steatosis.

Parra-Robert M, Casals E, Massana N, Zeng M, Perramón M, Fernández-Varo G, Morales-Ruiz M, Puntes V, Jiménez W, Casals G.

Biomolecules. 2019 Aug 29;9(9). pii: E425. doi: 10.3390/biom9090425.

4.

Functionalized cerium oxide nanoparticles mitigate the oxidative stress and pro-inflammatory activity associated to the portal vein endothelium of cirrhotic rats.

Ribera J, Rodríguez-Vita J, Cordoba B, Portolés I, Casals G, Casals E, Jiménez W, Puntes V, Morales-Ruiz M.

PLoS One. 2019 Jun 24;14(6):e0218716. doi: 10.1371/journal.pone.0218716. eCollection 2019.

5.

An integrative method to predict signalling perturbations for cellular transitions.

Zaffaroni G, Okawa S, Morales-Ruiz M, Del Sol A.

Nucleic Acids Res. 2019 Jul 9;47(12):e72. doi: 10.1093/nar/gkz232.

6.

Effects of Albumin Treatment on Systemic and Portal Hemodynamics and Systemic Inflammation in Patients With Decompensated Cirrhosis.

Fernández J, Clària J, Amorós A, Aguilar F, Castro M, Casulleras M, Acevedo J, Duran-Güell M, Nuñez L, Costa M, Torres M, Horrillo R, Ruiz-Del-Árbol L, Villanueva C, Prado V, Arteaga M, Trebicka J, Angeli P, Merli M, Alessandria C, Aagaard NK, Soriano G, Durand F, Gerbes A, Gustot T, Welzel TM, Salerno F, Bañares R, Vargas V, Albillos A, Silva A, Morales-Ruiz M, Carlos García-Pagán J, Pavesi M, Jalan R, Bernardi M, Moreau R, Páez A, Arroyo V.

Gastroenterology. 2019 Jul;157(1):149-162. doi: 10.1053/j.gastro.2019.03.021. Epub 2019 Mar 22.

7.

Neutrophil Gelatinase-Associated Lipocalin for Assessment of Acute Kidney Injury in Cirrhosis: A Prospective Study.

Huelin P, Solà E, Elia C, Solé C, Risso A, Moreira R, Carol M, Fabrellas N, Bassegoda O, Juanola A, de Prada G, Albertos S, Piano S, Graupera I, Ariza X, Napoleone L, Pose E, Filella X, Morales-Ruiz M, Rios J, Fernández J, Jiménez W, Poch E, Torres F, Ginès P.

Hepatology. 2019 Jul;70(1):319-333. doi: 10.1002/hep.30592. Epub 2019 Apr 25.

PMID:
30810244
8.

Characterization of inflammatory response in hepatorenal syndrome: Relationship with kidney outcome and survival.

Solé C, Solà E, Huelin P, Carol M, Moreira R, Cereijo U, Mas JM, Graupera I, Pose E, Napoleone L, dePrada G, Juanola A, Fabrellas N, Torres F, Morales-Ruiz M, Farrés J, Jiménez W, Ginès P.

Liver Int. 2019 Jul;39(7):1246-1255. doi: 10.1111/liv.14037. Epub 2019 Feb 17.

9.

A small population of liver endothelial cells undergoes endothelial-to-mesenchymal transition in response to chronic liver injury.

Ribera J, Pauta M, Melgar-Lesmes P, Córdoba B, Bosch A, Calvo M, Rodrigo-Torres D, Sancho-Bru P, Mira A, Jiménez W, Morales-Ruiz M.

Am J Physiol Gastrointest Liver Physiol. 2017 Nov 1;313(5):G492-G504. doi: 10.1152/ajpgi.00428.2016. Epub 2017 Aug 10.

10.

Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes.

Graupera I, Coll M, Pose E, Elia C, Piano S, Solà E, Blaya D, Huelin P, Solé C, Moreira R, de Prada G, Fabrellas N, Juanola A, Morales-Ruiz M, Sancho-Bru P, Villanueva C, Ginès P.

Sci Rep. 2017 May 12;7(1):1829. doi: 10.1038/s41598-017-01709-0.

11.

Effects of alfapump™ system on kidney and circulatory function in patients with cirrhosis and refractory ascites.

Solà E, Sanchez-Cabús S, Rodriguez E, Elia C, Cela R, Moreira R, Pose E, Sánchez-Delgado J, Cañete N, Morales-Ruiz M, Campos F, Balust J, Guevara M, García-Valdecasas JC, Ginès P.

Liver Transpl. 2017 May;23(5):583-593. doi: 10.1002/lt.24763.

12.

The Role of Akt in Chronic Liver Disease and Liver Regeneration.

Morales-Ruiz M, Santel A, Ribera J, Jiménez W.

Semin Liver Dis. 2017 Feb;37(1):11-16. doi: 10.1055/s-0036-1597819. Epub 2017 Feb 15. Review.

PMID:
28201844
13.

Identification of the potentially arrhythmogenic substrate in the acute phase of ST-segment elevation myocardial infarction.

Penela D, Acosta J, Andreu D, Ortiz-Perez JT, Bosch X, Perea RJ, de Caralt TM, Fernández-Armenta J, Soto-Iglesias D, Prat-Gonzalez S, Borràs R, Mont L, Hervas V, Morales-Ruiz M, Jiménez W, Mira A, Donnelly J, Ekinci O, Lasalvia L, Berruezo A.

Heart Rhythm. 2017 Apr;14(4):592-598. doi: 10.1016/j.hrthm.2017.01.019. Epub 2017 Jan 17.

PMID:
28104481
14.

Prognostic value of plasma apelin concentrations at admission in patients with ST-segment elevation acute myocardial infarction.

Sans-Roselló J, Casals G, Rossello X, González de la Presa B, Vila M, Duran-Cambra A, Morales-Ruiz M, Ferrero-Gregori A, Jiménez W, Sionis A.

Clin Biochem. 2017 Apr;50(6):279-284. doi: 10.1016/j.clinbiochem.2016.11.018. Epub 2016 Nov 24.

PMID:
27889567
15.

Plasma copeptin as biomarker of disease progression and prognosis in cirrhosis.

Solà E, Kerbert AJ, Verspaget HW, Moreira R, Pose E, Ruiz P, Cela R, Morales-Ruiz M, López E, Graupera I, Solé C, Huelin P, Navarro AA, Ariza X, Jalan R, Fabrellas N, Benten D, de Prada G, Durand F, Jimenez W, van der Reijden JJ, Fernandez J, van Hoek B, Coenraad MJ, Ginès P.

J Hepatol. 2016 Nov;65(5):914-920. doi: 10.1016/j.jhep.2016.07.003. Epub 2016 Jul 12.

16.

Characterization of Inflammatory Response in Acute-on-Chronic Liver Failure and Relationship with Prognosis.

Solé C, Solà E, Morales-Ruiz M, Fernàndez G, Huelin P, Graupera I, Moreira R, de Prada G, Ariza X, Pose E, Fabrellas N, Kalko SG, Jiménez W, Ginès P.

Sci Rep. 2016 Aug 31;6:32341. doi: 10.1038/srep32341.

17.

Utility of galectin-3 in predicting post-infarct remodeling after acute myocardial infarction based on extracellular volume fraction mapping.

Perea RJ, Morales-Ruiz M, Ortiz-Perez JT, Bosch X, Andreu D, Borras R, Acosta J, Penela D, Prat-González S, de Caralt TM, Martínez M, Morales-Romero B, Lasalvia L, Donnelly J, Jiménez W, Mira A, Mont L, Berruezo A.

Int J Cardiol. 2016 Nov 15;223:458-464. doi: 10.1016/j.ijcard.2016.08.070. Epub 2016 Aug 8.

PMID:
27544605
18.

Systemic inflammation in decompensated cirrhosis: Characterization and role in acute-on-chronic liver failure.

Clària J, Stauber RE, Coenraad MJ, Moreau R, Jalan R, Pavesi M, Amorós À, Titos E, Alcaraz-Quiles J, Oettl K, Morales-Ruiz M, Angeli P, Domenicali M, Alessandria C, Gerbes A, Wendon J, Nevens F, Trebicka J, Laleman W, Saliba F, Welzel TM, Albillos A, Gustot T, Benten D, Durand F, Ginès P, Bernardi M, Arroyo V; CANONIC Study Investigators of the EASL-CLIF Consortium and the European Foundation for the Study of Chronic Liver Failure (EF-CLIF).

Hepatology. 2016 Oct;64(4):1249-64. doi: 10.1002/hep.28740. Epub 2016 Aug 25.

19.

Urine Monocyte Chemoattractant Protein-1 Is an Independent Predictive Factor of Hospital Readmission and Survival in Cirrhosis.

Graupera I, Solà E, Fabrellas N, Moreira R, Solé C, Huelin P, de la Prada G, Pose E, Ariza X, Risso A, Albertos S, Morales-Ruiz M, Jiménez W, Ginès P.

PLoS One. 2016 Jun 30;11(6):e0157371. doi: 10.1371/journal.pone.0157371. eCollection 2016.

20.

Sipa1l1 is an early biomarker of liver fibrosis in CCl4-treated rats.

Marfà S, Morales-Ruiz M, Oró D, Ribera J, Fernández-Varo G, Jiménez W.

Biol Open. 2016 Jun 15;5(6):858-65. doi: 10.1242/bio.018887.

21.

Neutrophil gelatinase-associated lipocalin is a biomarker of acute-on-chronic liver failure and prognosis in cirrhosis.

Ariza X, Graupera I, Coll M, Solà E, Barreto R, García E, Moreira R, Elia C, Morales-Ruiz M, Llopis M, Huelin P, Solé C, Fabrellas N, Weiss E, Nevens F, Gerbes A, Trebicka J, Saliba F, Fondevila C, Hernández-Gea V, Fernández J, Bernardi M, Arroyo V, Jiménez W, Deulofeu C, Pavesi M, Angeli P, Jalan R, Moreau R, Sancho-Bru P, Ginès P; CANONIC Investigators, EASL CLIF Consortium.

J Hepatol. 2016 Jul;65(1):57-65. doi: 10.1016/j.jhep.2016.03.002. Epub 2016 Mar 14.

22.

Akt-mediated foxo1 inhibition is required for liver regeneration.

Pauta M, Rotllan N, Fernández-Hernando A, Langhi C, Ribera J, Lu M, Boix L, Bruix J, Jimenez W, Suárez Y, Ford DA, Baldán A, Birnbaum MJ, Morales-Ruiz M, Fernández-Hernando C.

Hepatology. 2016 May;63(5):1660-74. doi: 10.1002/hep.28286. Epub 2015 Dec 18.

23.

Prognosis of new-onset heart failure outpatients and collagen biomarkers.

Sanchis L, Andrea R, Falces C, Llopis J, Morales-Ruiz M, López-Sobrino T, Pérez-Villa F, Sitges M, Sabate M, Brugada J.

Eur J Clin Invest. 2015 Aug;45(8):842-9. doi: 10.1111/eci.12479. Epub 2015 Jul 14.

PMID:
26077878
24.

Analysis of a urinary biomarker panel for clinical outcomes assessment in cirrhosis.

Ariza X, Solà E, Elia C, Barreto R, Moreira R, Morales-Ruiz M, Graupera I, Rodríguez E, Huelin P, Solé C, Fernández J, Jiménez W, Arroyo V, Ginès P.

PLoS One. 2015 Jun 4;10(6):e0128145. doi: 10.1371/journal.pone.0128145. eCollection 2015.

25.

Lack of a 5.9 kDa peptide C-terminal fragment of fibrinogen α chain precedes fibrosis progression in patients with liver disease.

Marfà S, Crespo G, Reichenbach V, Forns X, Casals G, Morales-Ruiz M, Navasa M, Jiménez W.

PLoS One. 2014 Oct 2;9(10):e109254. doi: 10.1371/journal.pone.0109254. eCollection 2014.

26.

Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.

Lee MY, Luciano AK, Ackah E, Rodriguez-Vita J, Bancroft TA, Eichmann A, Simons M, Kyriakides TR, Morales-Ruiz M, Sessa WC.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12865-70. doi: 10.1073/pnas.1408472111. Epub 2014 Aug 18.

27.

Urinary neutrophil gelatinase-associated lipocalin predicts kidney outcome and death in patients with cirrhosis and bacterial infections.

Barreto R, Elia C, Solà E, Moreira R, Ariza X, Rodríguez E, Graupera I, Alfaro I, Morales-Ruiz M, Poch E, Guevara M, Fernández J, Jiménez W, Arroyo V, Ginès P.

J Hepatol. 2014 Jul;61(1):35-42. doi: 10.1016/j.jhep.2014.02.023. Epub 2014 Mar 5.

PMID:
24613364
28.

Overexpression of angiopoietin-2 in rats and patients with liver fibrosis. Therapeutic consequences of its inhibition.

Pauta M, Ribera J, Melgar-Lesmes P, Casals G, Rodríguez-Vita J, Reichenbach V, Fernandez-Varo G, Morales-Romero B, Bataller R, Michelena J, Altamirano J, Jiménez W, Morales-Ruiz M.

Liver Int. 2015 Apr;35(4):1383-92. doi: 10.1111/liv.12505. Epub 2014 Mar 11.

PMID:
24612347
29.

Factors involved in extracellular matrix turnover in human derived cardiomyocytes.

Casals G, Fernández-Varo G, Melgar-Lesmes P, Marfà S, Reichenbach V, Morales-Ruiz M, Jiménez W.

Cell Physiol Biochem. 2013;32(5):1125-36. doi: 10.1159/000354513. Epub 2013 Nov 11.

30.

Impaired liver regeneration in Ldlr-/- mice is associated with an altered hepatic profile of cytokines, growth factors, and lipids.

Pauta M, Rotllan N, Vales F, Fernandez-Hernando A, Allen RM, Ford DA, Marí M, Jiménez W, Baldán A, Morales-Ruiz M, Fernández-Hernando C.

J Hepatol. 2013 Oct;59(4):731-7. doi: 10.1016/j.jhep.2013.05.026. Epub 2013 May 24.

31.
32.

Down the liver sinusoidal endothelial cell (LSEC) hole. Is there a role for lipid rafts in LSEC fenestration?

Rodriguez-Vita J, Morales-Ruiz M.

Hepatology. 2013 Mar;57(3):1272-4. doi: 10.1002/hep.26249. Epub 2013 Feb 21. No abstract available.

PMID:
23426851
33.

Bacterial lipopolyshaccaride inhibits CB2 receptor expression in human monocytic cells.

Reichenbach V, Muñoz-Luque J, Ros J, Casals G, Navasa M, Fernández-Varo G, Morales-Ruiz M, Jiménez W.

Gut. 2013 Jul;62(7):1089-91. doi: 10.1136/gutjnl-2012-303662. Epub 2013 Jan 24. No abstract available.

PMID:
23348962
34.

Engineered zinc-finger proteins can compensate genetic haploinsufficiency by transcriptional activation of the wild-type allele: application to Willams-Beuren syndrome and supravalvular aortic stenosis.

Zhang P, Huang A, Morales-Ruiz M, Starcher BC, Huang Y, Sessa WC, Niklason LE, Giordano FJ.

Hum Gene Ther. 2012 Nov;23(11):1186-99. doi: 10.1089/hum.2011.201.

35.

Adenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats.

Reichenbach V, Fernández-Varo G, Casals G, Oró D, Ros J, Melgar-Lesmes P, Weiskirchen R, Morales-Ruiz M, Jiménez W.

J Hepatol. 2012 Nov;57(5):967-73. doi: 10.1016/j.jhep.2012.07.012. Epub 2012 Jul 20.

PMID:
22820479
36.

Admission B-type natriuretic peptide retains prognostic value in patients with acute coronary syndrome and preserved left ventricular ejection fraction.

Casals G, Azzalini L, Tomas C, Marfa S, Morales-Ruiz M, Heras M, Jimenez W, Sionis A.

Int J Cardiol. 2012 Jul 26;158(3):459-60. doi: 10.1016/j.ijcard.2012.05.020. Epub 2012 May 26. No abstract available.

PMID:
22633662
37.

Mir-33 regulates cell proliferation and cell cycle progression.

Cirera-Salinas D, Pauta M, Allen RM, Salerno AG, Ramírez CM, Chamorro-Jorganes A, Wanschel AC, Lasuncion MA, Morales-Ruiz M, Suarez Y, Baldan Á, Esplugues E, Fernández-Hernando C.

Cell Cycle. 2012 Mar 1;11(5):922-33. doi: 10.4161/cc.11.5.19421. Epub 2012 Mar 1.

38.

Increased nitric oxide production in lymphatic endothelial cells causes impairment of lymphatic drainage in cirrhotic rats.

Ribera J, Pauta M, Melgar-Lesmes P, Tugues S, Fernández-Varo G, Held KF, Soria G, Tudela R, Planas AM, Fernández-Hernando C, Arroyo V, Jiménez W, Morales-Ruiz M.

Gut. 2013 Jan;62(1):138-45. doi: 10.1136/gutjnl-2011-300703. Epub 2012 Jan 20.

PMID:
22267600
39.

Prevention of fibrosis progression in CCl4-treated rats: role of the hepatic endocannabinoid and apelin systems.

Reichenbach V, Ros J, Fernández-Varo G, Casals G, Melgar-Lesmes P, Campos T, Makriyannis A, Morales-Ruiz M, Jiménez W.

J Pharmacol Exp Ther. 2012 Mar;340(3):629-37. doi: 10.1124/jpet.111.188078. Epub 2011 Dec 7.

PMID:
22160265
40.

Circulating CO3-610, a degradation product of collagen III, closely reflects liver collagen and portal pressure in rats with fibrosis.

Segovia-Silvestre T, Reichenbach V, Fernández-Varo G, Vassiliadis E, Barascuk N, Morales-Ruiz M, Karsdal MA, Jiménez W.

Fibrogenesis Tissue Repair. 2011 Aug 3;4:19. doi: 10.1186/1755-1536-4-19.

41.

Prevention of chemotherapy-induced left ventricular dysfunction with enalapril and carvedilol: rationale and design of the OVERCOME trial.

Bosch X, Esteve J, Sitges M, de Caralt TM, Domènech A, Ortiz JT, Monzó M, Morales-Ruiz M, Perea RJ, Rovira M.

J Card Fail. 2011 Aug;17(8):643-8. doi: 10.1016/j.cardfail.2011.03.008. Epub 2011 May 6.

PMID:
21807325
42.

Glucocorticoid alternative effects on proliferating and differentiated mammary epithelium are associated to opposite regulation of cell-cycle inhibitor expression.

Hoijman E, Rocha-Viegas L, Kalko SG, Rubinstein N, Morales-Ruiz M, Joffé EB, Kordon EC, Pecci A.

J Cell Physiol. 2012 Apr;227(4):1721-30. doi: 10.1002/jcp.22896.

PMID:
21688264
43.

Inhibition of placental growth factor activity reduces the severity of fibrosis, inflammation, and portal hypertension in cirrhotic mice.

Van Steenkiste C, Ribera J, Geerts A, Pauta M, Tugues S, Casteleyn C, Libbrecht L, Olievier K, Schroyen B, Reynaert H, van Grunsven LA, Blomme B, Coulon S, Heindryckx F, De Vos M, Stassen JM, Vinckier S, Altamirano J, Bataller R, Carmeliet P, Van Vlierberghe H, Colle I, Morales-Ruiz M.

Hepatology. 2011 May;53(5):1629-40. doi: 10.1002/hep.24238.

PMID:
21520176
44.

Hypoxia and proinflammatory factors upregulate apelin receptor expression in human stellate cells and hepatocytes.

Melgar-Lesmes P, Pauta M, Reichenbach V, Casals G, Ros J, Bataller R, Morales-Ruiz M, Jiménez W.

Gut. 2011 Oct;60(10):1404-11. doi: 10.1136/gut.2010.234690. Epub 2011 Mar 29.

PMID:
21450694
45.

Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells.

Melgar-Lesmes P, Casals G, Pauta M, Ros J, Reichenbach V, Bataller R, Morales-Ruiz M, Jimenez W.

Endocrinology. 2010 Nov;151(11):5306-14. doi: 10.1210/en.2010-0754. Epub 2010 Sep 15.

PMID:
20843995
46.

Inactivation of extrahepatic vascular Akt improves systemic hemodynamics and sodium excretion in cirrhotic rats.

Fernández-Varo G, Melgar-Lesmes P, Casals G, Pauta M, Arroyo V, Morales-Ruiz M, Ros J, Jiménez W.

J Hepatol. 2010 Dec;53(6):1041-8. doi: 10.1016/j.jhep.2010.05.031. Epub 2010 Aug 3.

PMID:
20800923
47.

Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease.

Van de Veire S, Stalmans I, Heindryckx F, Oura H, Tijeras-Raballand A, Schmidt T, Loges S, Albrecht I, Jonckx B, Vinckier S, Van Steenkiste C, Tugues S, Rolny C, De Mol M, Dettori D, Hainaud P, Coenegrachts L, Contreres JO, Van Bergen T, Cuervo H, Xiao WH, Le Henaff C, Buysschaert I, Kharabi Masouleh B, Geerts A, Schomber T, Bonnin P, Lambert V, Haustraete J, Zacchigna S, Rakic JM, Jiménez W, Noël A, Giacca M, Colle I, Foidart JM, Tobelem G, Morales-Ruiz M, Vilar J, Maxwell P, Vinores SA, Carmeliet G, Dewerchin M, Claesson-Welsh L, Dupuy E, Van Vlierberghe H, Christofori G, Mazzone M, Detmar M, Collen D, Carmeliet P.

Cell. 2010 Apr 2;141(1):178-90. doi: 10.1016/j.cell.2010.02.039.

48.

Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells.

Sancho-Bru P, Juez E, Moreno M, Khurdayan V, Morales-Ruiz M, Colmenero J, Arroyo V, Brenner DA, Ginès P, Bataller R.

Liver Int. 2010 Jan;30(1):31-41. doi: 10.1111/j.1478-3231.2009.02161.x. Epub 2009 Nov 19.

PMID:
19929904
49.

Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes.

Casals G, Ros J, Sionis A, Davidson MM, Morales-Ruiz M, Jiménez W.

Am J Physiol Heart Circ Physiol. 2009 Aug;297(2):H550-5. doi: 10.1152/ajpheart.00250.2009. Epub 2009 Jun 19.

50.

LH/HCG stimulation of VEGF and adrenomedullin production by follicular fluid macrophages and luteinized granulosa cells.

Guimerà M, Morales-Ruiz M, Jiménez W, Balasch J.

Reprod Biomed Online. 2009 Jun;18(6):743-9.

PMID:
19490776

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