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Items: 36

1.

Leptin Induces Proadipogenic and Proinflammatory Signaling in Adipocytes.

Palhinha L, Liechocki S, Hottz ED, Pereira JADS, de Almeida CJ, Moraes-Vieira PMM, Bozza PT, Maya-Monteiro CM.

Front Endocrinol (Lausanne). 2019 Dec 13;10:841. doi: 10.3389/fendo.2019.00841. eCollection 2019.

2.

Ghrelin effects on mitochondrial fitness modulates macrophage function.

Corrêa da Silva F, Aguiar C, Pereira JAS, de Brito Monteiro L, Davanzo GG, Codo AC, Pimentel de Freitas L, Berti AS, Lopes Ferrucci D, Castelucci BG, Consonni SR, Carvalho HF, Moraes-Vieira PMM.

Free Radic Biol Med. 2019 Dec;145:61-66. doi: 10.1016/j.freeradbiomed.2019.09.012. Epub 2019 Sep 14.

PMID:
31525456
3.

PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice.

Syed I, Rubin de Celis MF, Mohan JF, Moraes-Vieira PM, Vijayakumar A, Nelson AT, Siegel D, Saghatelian A, Mathis D, Kahn BB.

J Clin Invest. 2019 Aug 5;129:3717-3731. doi: 10.1172/JCI122445. eCollection 2019 Aug 5.

4.

Mitochondria as central hub of the immune system.

Breda CNS, Davanzo GG, Basso PJ, Saraiva Câmara NO, Moraes-Vieira PMM.

Redox Biol. 2019 Sep;26:101255. doi: 10.1016/j.redox.2019.101255. Epub 2019 Jun 15. Review.

5.

Leptin in the regulation of the immunometabolism of adipose tissue-macrophages.

Monteiro L, Pereira JADS, Palhinha L, Moraes-Vieira PMM.

J Leukoc Biol. 2019 Sep;106(3):703-716. doi: 10.1002/JLB.MR1218-478R. Epub 2019 May 14. Review.

PMID:
31087711
6.

Castration-induced prostate epithelial cell apoptosis results from targeted oxidative stress attack of M1142 -macrophages.

Barbosa GO, Silva JAF, Siqueira-Berti A, Nishan U, Rosa-Ribeiro R, Oliveira SBP, Baratti MO, Ferrucci D, Santana JCO, Damas-Souza DM, Bruni-Cardoso A, Augusto TM, Corrêa-da-Silva F, Moraes-Vieira PM, Stach-Machado DR, Felisbino SL, Menezes GB, Cesar CL, Carvalho HF.

J Cell Physiol. 2019 Aug;234(10):19048-19058. doi: 10.1002/jcp.28544. Epub 2019 Mar 28.

PMID:
30924162
7.

Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects.

Syed I, Lee J, Peroni OD, Yore MM, Moraes-Vieira PM, Santoro A, Wellenstein K, Smith U, McGraw TE, Saghatelian A, Kahn BB.

Cell Metab. 2018 Oct 2;28(4):543-546. doi: 10.1016/j.cmet.2018.09.007. Epub 2018 Sep 20.

8.

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.

Syed I, Lee J, Moraes-Vieira PM, Donaldson CJ, Sontheimer A, Aryal P, Wellenstein K, Kolar MJ, Nelson AT, Siegel D, Mokrosinski J, Farooqi IS, Zhao JJ, Yore MM, Peroni OD, Saghatelian A, Kahn BB.

Cell Metab. 2018 Feb 6;27(2):419-427.e4. doi: 10.1016/j.cmet.2018.01.001.

9.

Mitoimmunity-when mitochondria dictates macrophage function.

Corrêa-da-Silva F, Pereira JAS, de Aguiar CF, de Moraes-Vieira PMM.

Cell Biol Int. 2018 Jun;42(6):651-655. doi: 10.1002/cbin.10921. Epub 2018 Jan 22. Review.

PMID:
29271525
10.

The Impact of Ghrelin in Metabolic Diseases: An Immune Perspective.

Pereira JADS, da Silva FC, de Moraes-Vieira PMM.

J Diabetes Res. 2017;2017:4527980. doi: 10.1155/2017/4527980. Epub 2017 Sep 7. Review.

11.

Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport.

Vijayakumar A, Aryal P, Wen J, Syed I, Vazirani RP, Moraes-Vieira PM, Camporez JP, Gallop MR, Perry RJ, Peroni OD, Shulman GI, Saghatelian A, McGraw TE, Kahn BB.

Cell Rep. 2017 Oct 24;21(4):1021-1035. doi: 10.1016/j.celrep.2017.09.091.

12.

Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88.

Castoldi A, Andrade-Oliveira V, Aguiar CF, Amano MT, Lee J, Miyagi MT, Latância MT, Braga TT, da Silva MB, Ignácio A, Carola Correia Lima JD, Loures FV, Albuquerque JAT, Macêdo MB, Almeida RR, Gaiarsa JW, Luévano-Martínez LA, Belchior T, Hiyane MI, Brown GD, Mori MA, Hoffmann C, Seelaender M, Festuccia WT, Moraes-Vieira PM, Câmara NOS.

Cell Rep. 2017 Jun 13;19(11):2272-2288. doi: 10.1016/j.celrep.2017.05.059.

13.

Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses.

Lee J, Moraes-Vieira PM, Castoldi A, Aryal P, Yee EU, Vickers C, Parnas O, Donaldson CJ, Saghatelian A, Kahn BB.

J Biol Chem. 2016 Oct 14;291(42):22207-22217. Epub 2016 Aug 29.

14.

GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects.

Moraes-Vieira PM, Saghatelian A, Kahn BB.

Diabetes. 2016 Jul;65(7):1808-15. doi: 10.2337/db16-0221. Epub 2016 Jun 10. Review.

15.

Antigen Presentation and T-Cell Activation Are Critical for RBP4-Induced Insulin Resistance.

Moraes-Vieira PM, Castoldi A, Aryal P, Wellenstein K, Peroni OD, Kahn BB.

Diabetes. 2016 May;65(5):1317-27. doi: 10.2337/db15-1696. Epub 2016 Mar 2.

16.

The Macrophage Switch in Obesity Development.

Castoldi A, Naffah de Souza C, Câmara NO, Moraes-Vieira PM.

Front Immunol. 2016 Jan 5;6:637. doi: 10.3389/fimmu.2015.00637. eCollection 2015. Review.

17.

They Must Hold Tight: Junction Proteins, Microbiota And Immunity In Intestinal Mucosa.

Castoldi A, Favero de Aguiar C, Moraes-Vieira PM, Olsen Saraiva Câmara N.

Curr Protein Pept Sci. 2015;16(7):655-71. Review.

PMID:
26122786
18.

Adipokines as drug targets in diabetes and underlying disturbances.

Andrade-Oliveira V, Câmara NO, Moraes-Vieira PM.

J Diabetes Res. 2015;2015:681612. doi: 10.1155/2015/681612. Epub 2015 Apr 8. Review.

19.

Leptin receptor signaling in T cells is required for Th17 differentiation.

Reis BS, Lee K, Fanok MH, Mascaraque C, Amoury M, Cohn LB, Rogoz A, Dallner OS, Moraes-Vieira PM, Domingos AI, Mucida D.

J Immunol. 2015 Jun 1;194(11):5253-60. doi: 10.4049/jimmunol.1402996. Epub 2015 Apr 27.

20.

Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation.

Toniolo PA, Liu S, Yeh JE, Moraes-Vieira PM, Walker SR, Vafaizadeh V, Barbuto JA, Frank DA.

J Immunol. 2015 Apr 1;194(7):3180-90. doi: 10.4049/jimmunol.1401635. Epub 2015 Feb 27.

21.

Gut Bacteria Products Prevent AKI Induced by Ischemia-Reperfusion.

Andrade-Oliveira V, Amano MT, Correa-Costa M, Castoldi A, Felizardo RJ, de Almeida DC, Bassi EJ, Moraes-Vieira PM, Hiyane MI, Rodas AC, Peron JP, Aguiar CF, Reis MA, Ribeiro WR, Valduga CJ, Curi R, Vinolo MA, Ferreira CM, Câmara NO.

J Am Soc Nephrol. 2015 Aug;26(8):1877-88. doi: 10.1681/ASN.2014030288. Epub 2015 Jan 14.

22.

Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice.

Zemany L, Bhanot S, Peroni OD, Murray SF, Moraes-Vieira PM, Castoldi A, Manchem P, Guo S, Monia BP, Kahn BB.

Diabetes. 2015 May;64(5):1603-14. doi: 10.2337/db14-0970. Epub 2014 Dec 18.

23.

Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.

Yore MM, Syed I, Moraes-Vieira PM, Zhang T, Herman MA, Homan EA, Patel RT, Lee J, Chen S, Peroni OD, Dhaneshwar AS, Hammarstedt A, Smith U, McGraw TE, Saghatelian A, Kahn BB.

Cell. 2014 Oct 9;159(2):318-32. doi: 10.1016/j.cell.2014.09.035.

24.

RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance.

Moraes-Vieira PM, Yore MM, Dwyer PM, Syed I, Aryal P, Kahn BB.

Cell Metab. 2014 Mar 4;19(3):512-26. doi: 10.1016/j.cmet.2014.01.018.

25.

Leptin deficiency impairs maturation of dendritic cells and enhances induction of regulatory T and Th17 cells.

Moraes-Vieira PM, Larocca RA, Bassi EJ, Peron JP, Andrade-Oliveira V, Wasinski F, Araujo R, Thornley T, Quintana FJ, Basso AS, Strom TB, Câmara NO.

Eur J Immunol. 2014 Mar;44(3):794-806. doi: 10.1002/eji.201343592. Epub 2014 Jan 13.

26.

Adipose tissue-derived mesenchymal stem cells increase skin allograft survival and inhibit Th-17 immune response.

Larocca RA, Moraes-Vieira PM, Bassi EJ, Semedo P, de Almeida DC, da Silva MB, Thornley T, Pacheco-Silva A, Câmara NO.

PLoS One. 2013 Oct 4;8(10):e76396. doi: 10.1371/journal.pone.0076396. eCollection 2013.

27.

A mouse variable gene fragment binds to DNA independently of the BCR context: a possible role for immature B-cell repertoire establishment.

Maranhão AQ, Costa MB, Guedes L, Moraes-Vieira PM, Raiol T, Brigido MM.

PLoS One. 2013 Sep 2;8(9):e72625. doi: 10.1371/journal.pone.0072625. eCollection 2013.

28.

Exercise and caloric restriction alter the immune system of mice submitted to a high-fat diet.

Wasinski F, Bacurau RF, Moraes MR, Haro AS, Moraes-Vieira PM, Estrela GR, Paredes-Gamero EJ, Barros CC, Almeida SS, Câmara NO, Araujo RC.

Mediators Inflamm. 2013;2013:395672. doi: 10.1155/2013/395672. Epub 2013 Mar 13.

29.

Leptin deficiency modulates allograft survival by favoring a Th2 and a regulatory immune profile. [corrected].

Moraes-Vieira PM, Bassi EJ, Larocca RA, Castoldi A, Burghos M, Lepique AP, Quintana FJ, Araujo RC, Basso AS, Strom TB, Câmara NO.

Am J Transplant. 2013 Jan;13(1):36-44. doi: 10.1111/j.1600-6143.2012.04283.x. Epub 2012 Sep 27. Erratum in: Am J Transplant. 2013 Aug;13(8):2231.

30.

Immune regulatory properties of allogeneic adipose-derived mesenchymal stem cells in the treatment of experimental autoimmune diabetes.

Bassi ÊJ, Moraes-Vieira PM, Moreira-Sá CS, Almeida DC, Vieira LM, Cunha CS, Hiyane MI, Basso AS, Pacheco-Silva A, Câmara NO.

Diabetes. 2012 Oct;61(10):2534-45. Epub 2012 Jun 11.

31.

TLR2, TLR4 and the MYD88 signaling pathway are crucial for neutrophil migration in acute kidney injury induced by sepsis.

Castoldi A, Braga TT, Correa-Costa M, Aguiar CF, Bassi ÊJ, Correa-Silva R, Elias RM, Salvador F, Moraes-Vieira PM, Cenedeze MA, Reis MA, Hiyane MI, Pacheco-Silva Á, Gonçalves GM, Saraiva Câmara NO.

PLoS One. 2012;7(5):e37584. doi: 10.1371/journal.pone.0037584. Epub 2012 May 24.

32.

Leptin as a link between the immune system and kidney-related diseases: leading actor or just a coadjuvant?

Moraes-Vieira PM, Bassi EJ, Araujo RC, Câmara NO.

Obes Rev. 2012 Aug;13(8):733-43. doi: 10.1111/j.1467-789X.2012.00997.x. Epub 2012 Apr 12. Review.

PMID:
22498577
33.

Preserving the B-cell compartment favors operational tolerance in human renal transplantation.

Silva HM, Takenaka MC, Moraes-Vieira PM, Monteiro SM, Hernandez MO, Chaara W, Six A, Agena F, Sesterheim P, Barbé-Tuana FM, Saitovitch D, Lemos F, Kalil J, Coelho V.

Mol Med. 2012 Jul 18;18:733-43. doi: 10.2119/molmed.2011.00281.

34.

GATA3 and a dominant regulatory gene expression profile discriminate operational tolerance in human transplantation.

Moraes-Vieira PM, Takenaka MC, Silva HM, Monteiro SM, Agena F, Lemos F, Saitovitch D, Kalil J, Coelho V.

Clin Immunol. 2012 Feb;142(2):117-26. doi: 10.1016/j.clim.2011.08.015. Epub 2011 Sep 16.

PMID:
22019771
35.

Exploring the role of soluble factors associated with immune regulatory properties of mesenchymal stem cells.

Bassi ÊJ, de Almeida DC, Moraes-Vieira PM, Câmara NO.

Stem Cell Rev Rep. 2012 Jun;8(2):329-42. doi: 10.1007/s12015-011-9311-1. Review.

PMID:
21881832
36.

Differential monocyte STAT6 activation and CD4(+)CD25(+)Foxp3(+) T cells in kidney operational tolerance transplanted individuals.

Moraes-Vieira PM, Silva HM, Takenaka MC, Monteiro SM, Lemos F, Saitovitch D, Kalil J, Coelho V.

Hum Immunol. 2010 May;71(5):442-50. doi: 10.1016/j.humimm.2010.01.022. Epub 2010 Feb 13.

PMID:
20122976

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