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Items: 1 to 50 of 63

1.

Timing of Introduction, Sensitization and Allergy to Highly-Allergenic Foods at Age 3 Years in a General-Population Canadian Cohort.

Simons E, Balshaw R, Lefebvre DL, Dai D, Turvey SE, Moraes TJ, Mandhane PJ, Azad MB, Sears MR, Subbarao P, Becker AB.

J Allergy Clin Immunol Pract. 2019 Oct 30. pii: S2213-2198(19)30903-1. doi: 10.1016/j.jaip.2019.09.039. [Epub ahead of print]

PMID:
31678300
2.

Early life exposure to phthalates in the Canadian Healthy Infant Longitudinal Development (CHILD) study: a multi-city birth cohort.

Navaranjan G, Takaro TK, Wheeler AJ, Diamond ML, Shu H, Azad MB, Becker AB, Dai R, Harris SA, Lefebvre DL, Lu Z, Mandhane PJ, McLean K, Moraes TJ, Scott JA, Turvey SE, Sears MR, Subbarao P, Brook JR.

J Expo Sci Environ Epidemiol. 2019 Oct 22. doi: 10.1038/s41370-019-0182-x. [Epub ahead of print]

PMID:
31641275
3.

Human milk fatty acid composition is associated with dietary, genetic, sociodemographic, and environmental factors in the CHILD Cohort Study.

Miliku K, Duan QL, Moraes TJ, Becker AB, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR, Subbarao P, Field CJ, Azad MB.

Am J Clin Nutr. 2019 Oct 7. pii: nqz229. doi: 10.1093/ajcn/nqz229. [Epub ahead of print]

PMID:
31589250
4.

Exercise-induced laryngeal obstruction: Quality initiative to improve assessment and management.

Campisi ES, Schneiderman JE, Owen B, Moraes TJ, Campisi P.

Int J Pediatr Otorhinolaryngol. 2019 Sep 11;127:109677. doi: 10.1016/j.ijporl.2019.109677. [Epub ahead of print]

PMID:
31526937
5.

Prenatal exposure to traffic-related air pollution, the gestational epigenetic clock, and risk of early-life allergic sensitization.

Sbihi H, Jones MJ, MacIsaac JL, Brauer M, Allen RW, Sears MR, Subbarao P, Mandhane PJ, Moraes TJ, Azad MB, Becker AB, Brook JR, Kobor MS, Turvey SE.

J Allergy Clin Immunol. 2019 Aug 27. pii: S0091-6749(19)31101-7. doi: 10.1016/j.jaci.2019.07.047. [Epub ahead of print] No abstract available.

PMID:
31470034
6.

ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel.

Wu YS, Jiang J, Ahmadi S, Lew A, Laselva O, Xia S, Bartlett C, Ip W, Wellhauser L, Ouyang H, Gonska T, Moraes TJ, Bear CE.

Mol Pharmacol. 2019 Oct;96(4):515-525. doi: 10.1124/mol.119.117143. Epub 2019 Aug 19.

PMID:
31427400
7.

Reduced genetic potential for butyrate fermentation in the gut microbiome of infants who develop allergic sensitization.

Cait A, Cardenas E, Dimitriu PA, Amenyogbe N, Dai D, Cait J, Sbihi H, Stiemsma L, Subbarao P, Mandhane PJ, Becker AB, Moraes TJ, Sears MR, Lefebvre DL, Azad MB, Kollmann T, Turvey SE, Mohn WW.

J Allergy Clin Immunol. 2019 Jul 3. pii: S0091-6749(19)30891-7. doi: 10.1016/j.jaci.2019.06.029. [Epub ahead of print]

PMID:
31279007
8.

Patterns of health care use related to respiratory conditions in early life: A birth cohort study with linked administrative data.

Chen W, Subbarao P, McGihon RE, Feldman LY, Zhu J, Lou W, Gershon AS, Abdullah K, Moraes TJ, Dubeau A, Sears MR, Lefebvre DL, Turvey SE, Mandhane PJ, Azad MB, To T.

Pediatr Pulmonol. 2019 Aug;54(8):1267-1276. doi: 10.1002/ppul.24381. Epub 2019 Jun 6.

PMID:
31172683
9.

Integrated Analysis of Human Milk Microbiota With Oligosaccharides and Fatty Acids in the CHILD Cohort.

Moossavi S, Atakora F, Miliku K, Sepehri S, Robertson B, Duan QL, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Lefebvre DL, Sears MR, Subbarao P, Field CJ, Bode L, Khafipour E, Azad MB.

Front Nutr. 2019 May 16;6:58. doi: 10.3389/fnut.2019.00058. eCollection 2019.

10.

Prenatal depression and birth mode sequentially mediate maternal education's influence on infant sleep duration.

Matenchuk BA, Tamana SK, Lou WYW, Lefebvre DL, Sears MR, Becker AB, Azad MB, Moraes TJ, Turvey SE, Subbarao P, Kozyrskyj AL, Mandhane PJ; CHILD Study Investigators.

Sleep Med. 2019 Jul;59:24-32. doi: 10.1016/j.sleep.2019.01.015. Epub 2019 Jan 29.

PMID:
31153013
11.

Extract and component-specific sensitization patterns in Canadian moderate-to-severe preschool asthmatics.

Hoang JA, Mashouri P, Dai R, Brydges MG, Dubeau A, Lépine C, Yin X, Kowalik K, DeLorenzo S, Upton JEM, Moraes TJ, Amin R, Narang I, Boutis K, Schuh S, Maksym GN, Brudno M, Ramani A, Subbarao P, Eiwegger T.

Allergy. 2019 May 24. doi: 10.1111/all.13927. [Epub ahead of print] No abstract available.

PMID:
31125434
12.

Screen-time is associated with inattention problems in preschoolers: Results from the CHILD birth cohort study.

Tamana SK, Ezeugwu V, Chikuma J, Lefebvre DL, Azad MB, Moraes TJ, Subbarao P, Becker AB, Turvey SE, Sears MR, Dick BD, Carson V, Rasmussen C; CHILD study Investigators, Pei J, Mandhane PJ.

PLoS One. 2019 Apr 17;14(4):e0213995. doi: 10.1371/journal.pone.0213995. eCollection 2019.

13.

Associations between concentrations of perfluoroalkyl substances in human plasma and maternal, infant, and home characteristics in Winnipeg, Canada.

Workman CE, Becker AB, Azad MB, Moraes TJ, Mandhane PJ, Turvey SE, Subbarao P, Brook JR, Sears MR, Wong CS.

Environ Pollut. 2019 Jun;249:758-766. doi: 10.1016/j.envpol.2019.03.054. Epub 2019 Mar 21.

PMID:
30933773
14.

Requirement and Duration of Tube Feed Supplementation among Congenital Diaphragmatic Hernia Patients.

Wong MKW, Haliburton B, Graham A, Lapidus-Krol E, Moraes TJ, Marcon MA, Chiu PPL.

J Pediatr Surg. 2019 May;54(5):895-898. doi: 10.1016/j.jpedsurg.2019.01.017. Epub 2019 Jan 31.

PMID:
30773392
15.

Composition and Variation of the Human Milk Microbiota Are Influenced by Maternal and Early-Life Factors.

Moossavi S, Sepehri S, Robertson B, Bode L, Goruk S, Field CJ, Lix LM, de Souza RJ, Becker AB, Mandhane PJ, Turvey SE, Subbarao P, Moraes TJ, Lefebvre DL, Sears MR, Khafipour E, Azad MB.

Cell Host Microbe. 2019 Feb 13;25(2):324-335.e4. doi: 10.1016/j.chom.2019.01.011.

PMID:
30763539
16.

Associations between meeting the Canadian 24-Hour Movement Guidelines for the Early Years and behavioral and emotional problems among 3-year-olds.

Carson V, Ezeugwu VE, Tamana SK, Chikuma J, Lefebvre DL, Azad MB, Moraes TJ, Subbarao P, Becker AB, Turvey SE, Sears MR, Mandhane PJ.

J Sci Med Sport. 2019 Jul;22(7):797-802. doi: 10.1016/j.jsams.2019.01.003. Epub 2019 Jan 10.

PMID:
30655179
17.

Predictors of Long-Term Pulmonary Morbidity in Children with Congenital Diaphragmatic Hernia.

Wigen RB, Duan W, Moraes TJ, Chiu PPL.

Eur J Pediatr Surg. 2019 Feb;29(1):120-124. doi: 10.1055/s-0038-1676586. Epub 2018 Dec 24.

PMID:
30583297
18.

Diagnosing atopic dermatitis in infancy: Questionnaire reports vs criteria-based assessment.

Dharma C, Lefebvre DL, Tran MM, Lu Z, Lou WYW, Subbarao P, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Azad MB, Sears MR; CHILD Study Investigators.

Paediatr Perinat Epidemiol. 2018 Nov;32(6):556-567. doi: 10.1111/ppe.12525. Epub 2018 Nov 21.

PMID:
30461044
19.

Infant Feeding and Weight Gain: Separating Breast Milk From Breastfeeding and Formula From Food.

Azad MB, Vehling L, Chan D, Klopp A, Nickel NC, McGavock JM, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Taylor MS, Lefebvre DL, Sears MR, Subbarao P; CHILD Study Investigators.

Pediatrics. 2018 Oct;142(4). pii: e20181092. doi: 10.1542/peds.2018-1092.

20.

Human Milk Oligosaccharide Concentrations Are Associated with Multiple Fixed and Modifiable Maternal Characteristics, Environmental Factors, and Feeding Practices.

Azad MB, Robertson B, Atakora F, Becker AB, Subbarao P, Moraes TJ, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR, Bode L.

J Nutr. 2018 Nov 1;148(11):1733-1742. doi: 10.1093/jn/nxy175.

PMID:
30247646
21.

Targeting Intracellular Ion Homeostasis for the Control of Respiratory Syncytial Virus.

Norris MJ, Malhi M, Duan W, Ouyang H, Granados A, Cen Y, Tseng YC, Gubbay J, Maynes J, Moraes TJ.

Am J Respir Cell Mol Biol. 2018 Dec;59(6):733-744. doi: 10.1165/rcmb.2017-0345OC.

PMID:
30095982
22.

Risk for Maternal Depressive Symptoms and Perceived Stress by Ethnicities in Canada: From Pregnancy Through the Preschool Years.

Dharma C, Lefebvre DL, Lu Z, Lou WYW, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Azad MB, Chen E, Elliott SJ, Kozyrskyj AL, Sears MR, Subbarao P.

Can J Psychiatry. 2019 Mar;64(3):190-198. doi: 10.1177/0706743718792190. Epub 2018 Aug 1.

23.

Ventilation inhomogeneity in infants with recurrent wheezing.

Lu Z, Foong RE, Kowalik K, Moraes TJ, Boyce A, Dubeau A, Balkovec S, Gustafsson PM, Becker AB, Mandhane PJ, Turvey SE, Lou W, Ratjen F, Sears M, Subbarao P.

Thorax. 2018 Oct;73(10):936-941. doi: 10.1136/thoraxjnl-2017-211351. Epub 2018 Jun 15.

PMID:
29907664
24.

Association of Exposure to Formula in the Hospital and Subsequent Infant Feeding Practices With Gut Microbiota and Risk of Overweight in the First Year of Life.

Forbes JD, Azad MB, Vehling L, Tun HM, Konya TB, Guttman DS, Field CJ, Lefebvre D, Sears MR, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Subbarao P, Scott JA, Kozyrskyj AL; Canadian Healthy Infant Longitudinal Development (CHILD) Study Investigators.

JAMA Pediatr. 2018 Jul 2;172(7):e181161. doi: 10.1001/jamapediatrics.2018.1161. Epub 2018 Jul 2. Erratum in: JAMA Pediatr. 2018 Jul 1;172(7):704.

25.

Reference equations for the interpretation of forced expiratory and plethysmographic measurements in infants.

Lu Z, Foong RE, Kowalik K, Moraes TJ, Dubeau A, Lefebvre D, Davis SD, Balkovec S, Becker A, Mandhane P, Turvey SE, Lou W, Sears MR, Ratjen F, Subbarao P.

Pediatr Pulmonol. 2018 Jul;53(7):907-916. doi: 10.1002/ppul.24063. Epub 2018 May 23.

PMID:
29790670
26.

The CF Canada-Sick Kids Program in individual CF therapy: A resource for the advancement of personalized medicine in CF.

Eckford PDW, McCormack J, Munsie L, He G, Stanojevic S, Pereira SL, Ho K, Avolio J, Bartlett C, Yang JY, Wong AP, Wellhauser L, Huan LJ, Jiang JX, Ouyang H, Du K, Klingel M, Kyriakopoulou L, Gonska T, Moraes TJ, Strug LJ, Rossant J, Ratjen F, Bear CE.

J Cyst Fibros. 2019 Jan;18(1):35-43. doi: 10.1016/j.jcf.2018.03.013. Epub 2018 Oct 10.

27.

Exclusive breastfeeding in hospital predicts longer breastfeeding duration in Canada: Implications for health equity.

Vehling L, Chan D, McGavock J, Becker AB, Subbarao P, Moraes TJ, Mandhane PJ, Turvey SE, Lefebvre DL, Sears MR, Azad MB.

Birth. 2018 Dec;45(4):440-449. doi: 10.1111/birt.12345. Epub 2018 Mar 2.

PMID:
29498088
28.

Long-term follow-up of cardiorespiratory outcomes in children born extremely preterm: Recommendations from a Canadian consensus workshop.

Katz SL, Luu TM, Nuyt AM, Lacaze T, Adamo KB, Adatia I, Humpl T, Jankov RP, Moraes TJ, Staub K, Stickland MK, Thebaud B; Long-term Cardio-Respiratory Outcomes of Extremely Preterm Infants Working Group.

Paediatr Child Health. 2017 May;22(2):75-79. doi: 10.1093/pch/pxx028. Epub 2017 Apr 17. Review.

29.

Epidemiology of Asthma and Influence of Ethnicity.

Moraes TJ, Sears MR, Subbarao P.

Semin Respir Crit Care Med. 2018 Feb;39(1):3-11. doi: 10.1055/s-0037-1618568. Epub 2018 Feb 10. Review.

PMID:
29427980
30.

Transducing Airway Basal Cells with a Helper-Dependent Adenoviral Vector for Lung Gene Therapy.

Cao H, Ouyang H, Grasemann H, Bartlett C, Du K, Duan R, Shi F, Estrada M, Seigel KE, Coates AL, Yeger H, Bear CE, Gonska T, Moraes TJ, Hu J.

Hum Gene Ther. 2018 Jun;29(6):643-652. doi: 10.1089/hum.2017.201. Epub 2018 Mar 16.

PMID:
29320887
31.

Lower respiratory infections in early life are linked to later asthma.

Moraes TJ, Sears MR.

Thorax. 2018 Feb;73(2):105-106. doi: 10.1136/thoraxjnl-2017-211104. Epub 2017 Nov 23. No abstract available.

PMID:
29170249
32.

Targeting Host Cell Surface Nucleolin for RSV Therapy: Challenges and Opportunities.

Mastrangelo P, Norris MJ, Duan W, Barrett EG, Moraes TJ, Hegele RG.

Vaccines (Basel). 2017 Sep 19;5(3). pii: E27. doi: 10.3390/vaccines5030027.

33.

Orkambi® and amplifier co-therapy improves function from a rare CFTR mutation in gene-edited cells and patient tissue.

Molinski SV, Ahmadi S, Ip W, Ouyang H, Villella A, Miller JP, Lee PS, Kulleperuma K, Du K, Di Paola M, Eckford PD, Laselva O, Huan LJ, Wellhauser L, Li E, Ray PN, Pomès R, Moraes TJ, Gonska T, Ratjen F, Bear CE.

EMBO Mol Med. 2017 Sep;9(9):1224-1243. doi: 10.15252/emmm.201607137.

34.

Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia.

Ahmadi S, Bozoky Z, Di Paola M, Xia S, Li C, Wong AP, Wellhauser L, Molinski SV, Ip W, Ouyang H, Avolio J, Forman-Kay JD, Ratjen F, Hirota JA, Rommens J, Rossant J, Gonska T, Moraes TJ, Bear CE.

NPJ Genom Med. 2017 Apr 14;2:12. doi: 10.1038/s41525-017-0015-6.

35.

Cost-effectiveness of palivizumab compared to no prophylaxis in term infants residing in the Canadian Arctic.

Banerji A, Ng K, Moraes TJ, Panzov V, Robinson J, Lee BE.

CMAJ Open. 2016 Oct 18;4(4):E623-E633. doi: 10.9778/cmajo.20150052. eCollection 2016 Oct-Dec.

36.

Intelligent volume-assured pressured support (iVAPS) for the treatment of congenital central hypoventilation syndrome.

Khayat A, Medin D, Syed F, Moraes TJ, Bin-Hasan S, Narang I, Al-Saleh S, Amin R.

Sleep Breath. 2017 May;21(2):513-519. doi: 10.1007/s11325-017-1478-5. Epub 2017 Feb 11.

PMID:
28190166
37.

Pulmonary function and nutritional morbidity in children and adolescents with congenital diaphragmatic hernia.

Haliburton B, Mouzaki M, Chiang M, Scaini V, Marcon M, Duan W, Wilson D, Chiu PP, Moraes TJ.

J Pediatr Surg. 2017 Feb;52(2):252-256. doi: 10.1016/j.jpedsurg.2016.11.020. Epub 2016 Nov 14.

PMID:
27912974
38.

Testing gene therapy vectors in human primary nasal epithelial cultures.

Cao H, Ouyang H, Ip W, Du K, Duan W, Avolio J, Wu J, Duan C, Yeger H, Bear CE, Gonska T, Hu J, Moraes TJ.

Mol Ther Methods Clin Dev. 2015 Sep 9;2:15034. doi: 10.1038/mtm.2015.34. eCollection 2015.

39.

Agonistic 4-1BB antibody fails to reduce disease burden during acute respiratory syncytial virus (RSV) infection.

Norris MJ, Duan W, Cen Y, Moraes TJ.

Antiviral Res. 2016 Jan;125:46-50. doi: 10.1016/j.antiviral.2015.10.007. Epub 2015 Nov 17.

PMID:
26597692
40.

Nutritional Intake, Energy Expenditure, and Growth of Infants Following Congenital Diaphragmatic Hernia Repair.

Haliburton B, Chiang M, Marcon M, Moraes TJ, Chiu PP, Mouzaki M.

J Pediatr Gastroenterol Nutr. 2016 Mar;62(3):474-8. doi: 10.1097/MPG.0000000000001000.

PMID:
26465794
41.

The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma.

Subbarao P, Anand SS, Becker AB, Befus AD, Brauer M, Brook JR, Denburg JA, HayGlass KT, Kobor MS, Kollmann TR, Kozyrskyj AL, Lou WY, Mandhane PJ, Miller GE, Moraes TJ, Pare PD, Scott JA, Takaro TK, Turvey SE, Duncan JM, Lefebvre DL, Sears MR; CHILD Study investigators.

Thorax. 2015 Oct;70(10):998-1000. doi: 10.1136/thoraxjnl-2015-207246. Epub 2015 Jun 11.

PMID:
26069286
42.

How long does it take to initiate a child on long-term invasive ventilation? Results from a Canadian pediatric home ventilation program.

Amin R, Sayal A, Syed F, Daniels C, Hoffman A, Moraes TJ, Cox P.

Can Respir J. 2015 Mar-Apr;22(2):103-8.

43.

Long-term nutritional morbidity for congenital diaphragmatic hernia survivors: Failure to thrive extends well into childhood and adolescence.

Haliburton B, Mouzaki M, Chiang M, Scaini V, Marcon M, Moraes TJ, Chiu PP.

J Pediatr Surg. 2015 May;50(5):734-8. doi: 10.1016/j.jpedsurg.2015.02.026. Epub 2015 Feb 20.

PMID:
25783378
44.

The Canadian healthy infant longitudinal development birth cohort study: biological samples and biobanking.

Moraes TJ, Lefebvre DL, Chooniedass R, Becker AB, Brook JR, Denburg J, HayGlass KT, Hegele RG, Kollmann TR, Macri J, Mandhane PJ, Scott JA, Subbarao P, Takaro TK, Turvey SE, Duncan JD, Sears MR, Befus AD; CHILD Study Investigators.

Paediatr Perinat Epidemiol. 2015 Jan;29(1):84-92. doi: 10.1111/ppe.12161. Epub 2014 Nov 18.

PMID:
25405552
45.

Respiratory syncytial virus receptor expression in the mouse and viral tropism.

Shakeri A, Mastrangelo P, Griffin JK, Moraes TJ, Hegele RG.

Histol Histopathol. 2015 Apr;30(4):401-11. doi: 10.14670/HH-30.401. Epub 2014 Nov 6. Review.

PMID:
25374027
46.

A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity.

Marchant DJ, Bellac CL, Moraes TJ, Wadsworth SJ, Dufour A, Butler GS, Bilawchuk LM, Hendry RG, Robertson AG, Cheung CT, Ng J, Ang L, Luo Z, Heilbron K, Norris MJ, Duan W, Bucyk T, Karpov A, Devel L, Georgiadis D, Hegele RG, Luo H, Granville DJ, Dive V, McManus BM, Overall CM.

Nat Med. 2014 May;20(5):493-502. doi: 10.1038/nm.3508. Epub 2014 Apr 28.

PMID:
24784232
47.

Pediatric long-term home mechanical ventilation: twenty years of follow-up from one Canadian center.

Amin R, Sayal P, Syed F, Chaves A, Moraes TJ, MacLusky I.

Pediatr Pulmonol. 2014 Aug;49(8):816-24. doi: 10.1002/ppul.22868. Epub 2013 Sep 2.

PMID:
24000198
48.

Diagnostic practices and disease surveillance in Canadian children with congenital central hypoventilation syndrome.

Amin R, Moraes TJ, Skitch A, Irwin MS, Meyn S, Witmans M.

Can Respir J. 2013 May-Jun;20(3):165-70.

49.

Influenza infects lung microvascular endothelium leading to microvascular leak: role of apoptosis and claudin-5.

Armstrong SM, Wang C, Tigdi J, Si X, Dumpit C, Charles S, Gamage A, Moraes TJ, Lee WL.

PLoS One. 2012;7(10):e47323. doi: 10.1371/journal.pone.0047323. Epub 2012 Oct 24.

50.

T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy.

Snell LM, Lin GH, McPherson AJ, Moraes TJ, Watts TH.

Immunol Rev. 2011 Nov;244(1):197-217. doi: 10.1111/j.1600-065X.2011.01063.x. Review. Erratum in: Immunol Rev. 2012 Jan;245(1):265.

PMID:
22017440

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