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Items: 1 to 50 of 70

1.

GlcNAc De-N-Acetylase from the Hyperthermophilic Archaeon Sulfolobus solfataricus.

Iacono R, Strazzulli A, Maurelli L, Curci N, Casillo A, Corsaro MM, Moracci M, Cobucci-Ponzano B.

Appl Environ Microbiol. 2019 Jan 9;85(2). pii: e01879-18. doi: 10.1128/AEM.01879-18. Print 2019 Jan 15.

PMID:
30446550
2.

Structural and functional insights into RHA-P, a bacterial GH106 α-L-rhamnosidase from Novosphingobium sp. PP1Y.

Mensitieri F, De Lise F, Strazzulli A, Moracci M, Notomista E, Cafaro V, Bedini E, Sazinsky MH, Trifuoggi M, Di Donato A, Izzo V.

Arch Biochem Biophys. 2018 Jun 15;648:1-11. doi: 10.1016/j.abb.2018.04.013. Epub 2018 Apr 18.

PMID:
29678627
3.

Conversion of xylan by recyclable spores of Bacillus subtilis displaying thermophilic enzymes.

Mattossovich R, Iacono R, Cangiano G, Cobucci-Ponzano B, Isticato R, Moracci M, Ricca E.

Microb Cell Fact. 2017 Nov 28;16(1):218. doi: 10.1186/s12934-017-0833-3.

4.

N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer of α-Glucosidase Activity for the Treatment of Pompe Disease.

D'Alonzo D, De Fenza M, Porto C, Iacono R, Huebecker M, Cobucci-Ponzano B, Priestman DA, Platt F, Parenti G, Moracci M, Palumbo G, Guaragna A.

J Med Chem. 2017 Dec 14;60(23):9462-9469. doi: 10.1021/acs.jmedchem.7b00646. Epub 2017 Nov 22.

PMID:
29112434
5.

Structure of human lysosomal acid α-glucosidase-a guide for the treatment of Pompe disease.

Roig-Zamboni V, Cobucci-Ponzano B, Iacono R, Ferrara MC, Germany S, Bourne Y, Parenti G, Moracci M, Sulzenbacher G.

Nat Commun. 2017 Oct 24;8(1):1111. doi: 10.1038/s41467-017-01263-3.

6.

Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island.

Antranikian G, Suleiman M, Schäfers C, Adams MWW, Bartolucci S, Blamey JM, Birkeland NK, Bonch-Osmolovskaya E, da Costa MS, Cowan D, Danson M, Forterre P, Kelly R, Ishino Y, Littlechild J, Moracci M, Noll K, Oshima T, Robb F, Rossi M, Santos H, Schönheit P, Sterner R, Thauer R, Thomm M, Wiegel J, Stetter KO.

Extremophiles. 2017 Jul;21(4):733-742. doi: 10.1007/s00792-017-0938-y. Epub 2017 May 10.

PMID:
28493148
7.

Human a-L-fucosidase-1 attenuates the invasive properties of thyroid cancer.

Vecchio G, Parascandolo A, Allocca C, Ugolini C, Basolo F, Moracci M, Strazzulli A, Cobucci-Ponzano B, Laukkanen MO, Castellone MD, Tsuchida N.

Oncotarget. 2017 Apr 18;8(16):27075-27092. doi: 10.18632/oncotarget.15635.

8.

Introducing transgalactosylation activity into a family 42 β-galactosidase.

Strazzulli A, Cobucci-Ponzano B, Carillo S, Bedini E, Corsaro MM, Pocsfalvi G, Withers SG, Rossi M, Moracci M.

Glycobiology. 2017 May 1;27(5):425-437. doi: 10.1093/glycob/cwx013.

PMID:
28158578
9.

Structural basis of laminin binding to the LARGE glycans on dystroglycan.

Briggs DC, Yoshida-Moriguchi T, Zheng T, Venzke D, Anderson ME, Strazzulli A, Moracci M, Yu L, Hohenester E, Campbell KP.

Nat Chem Biol. 2016 Oct;12(10):810-4. doi: 10.1038/nchembio.2146. Epub 2016 Aug 15.

10.

High-level expression of thermostable cellulolytic enzymes in tobacco transplastomic plants and their use in hydrolysis of an industrially pretreated Arundo donax L. biomass.

Castiglia D, Sannino L, Marcolongo L, Ionata E, Tamburino R, De Stradis A, Cobucci-Ponzano B, Moracci M, La Cara F, Scotti N.

Biotechnol Biofuels. 2016 Jul 22;9:154. doi: 10.1186/s13068-016-0569-z. eCollection 2016.

11.

Novel thermophilic hemicellulases for the conversion of lignocellulose for second generation biorefineries.

Cobucci-Ponzano B, Strazzulli A, Iacono R, Masturzo G, Giglio R, Rossi M, Moracci M.

Enzyme Microb Technol. 2015 Oct;78:63-73. doi: 10.1016/j.enzmictec.2015.06.014. Epub 2015 Jun 25.

PMID:
26215346
12.

Comparative Metagenomics of Eight Geographically Remote Terrestrial Hot Springs.

Menzel P, Gudbergsdóttir SR, Rike AG, Lin L, Zhang Q, Contursi P, Moracci M, Kristjansson JK, Bolduc B, Gavrilov S, Ravin N, Mardanov A, Bonch-Osmolovskaya E, Young M, Krogh A, Peng X.

Microb Ecol. 2015 Aug;70(2):411-24. doi: 10.1007/s00248-015-0576-9. Epub 2015 Feb 25.

PMID:
25712554
13.

Pharmacological chaperone therapy for lysosomal storage diseases.

Parenti G, Moracci M, Fecarotta S, Andria G.

Future Med Chem. 2014 Jun;6(9):1031-45. doi: 10.4155/fmc.14.40. Review.

PMID:
25068986
14.

RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code.

Di Giulio M, Moracci M, Cobucci-Ponzano B.

J Theor Biol. 2014 Oct 21;359:1-5. doi: 10.1016/j.jtbi.2014.05.037. Epub 2014 Jun 6.

PMID:
24911781
15.

The identification and molecular characterization of the first archaeal bifunctional exo-β-glucosidase/N-acetyl-β-glucosaminidase demonstrate that family GH116 is made of three functionally distinct subfamilies.

Ferrara MC, Cobucci-Ponzano B, Carpentieri A, Henrissat B, Rossi M, Amoresano A, Moracci M.

Biochim Biophys Acta. 2014 Jan;1840(1):367-77. doi: 10.1016/j.bbagen.2013.09.022. Epub 2013 Sep 21.

PMID:
24060745
16.

Translational recoding in archaea.

Cobucci-Ponzano B, Rossi M, Moracci M.

Extremophiles. 2012 Nov;16(6):793-803. doi: 10.1007/s00792-012-0482-8. Epub 2012 Sep 27. Review.

PMID:
23015064
17.

Pharmacological enhancement of α-glucosidase by the allosteric chaperone N-acetylcysteine.

Porto C, Ferrara MC, Meli M, Acampora E, Avolio V, Rosa M, Cobucci-Ponzano B, Colombo G, Moracci M, Andria G, Parenti G.

Mol Ther. 2012 Dec;20(12):2201-11. doi: 10.1038/mt.2012.152. Epub 2012 Sep 18.

18.

Adsorption of β-galactosidase of Alicyclobacillus acidocaldarius on wild type and mutants spores of Bacillus subtilis.

Sirec T, Strazzulli A, Isticato R, De Felice M, Moracci M, Ricca E.

Microb Cell Fact. 2012 Aug 3;11:100. doi: 10.1186/1475-2859-11-100.

19.

Thermophilic glycosynthases for oligosaccharides synthesis.

Cobucci-Ponzano B, Perugino G, Strazzulli A, Rossi M, Moracci M.

Methods Enzymol. 2012;510:273-300. doi: 10.1016/B978-0-12-415931-0.00015-X.

PMID:
22608732
20.

Glycosynthases as tools for the production of glycan analogs of natural products.

Cobucci-Ponzano B, Moracci M.

Nat Prod Rep. 2012 Jun;29(6):697-709. doi: 10.1039/c2np20032e. Epub 2012 Apr 16. Review.

PMID:
22504390
21.

A novel alpha-D-galactosynthase from Thermotoga maritima converts beta-D-galactopyranosyl azide to alpha-galacto-oligosaccharides.

Cobucci-Ponzano B, Zorzetti C, Strazzulli A, Carillo S, Bedini E, Corsaro MM, Comfort DA, Kelly RM, Rossi M, Moracci M.

Glycobiology. 2011 Apr;21(4):448-56. doi: 10.1093/glycob/cwq177. Epub 2010 Nov 17.

PMID:
21084405
22.

Engineering the stability and the activity of a glycoside hydrolase.

Cobucci-Ponzano B, Perugino G, Rossi M, Moracci M.

Protein Eng Des Sel. 2011 Jan;24(1-2):21-6. doi: 10.1093/protein/gzq085. Epub 2010 Oct 27. Review.

PMID:
20980336
23.

The molecular characterization of a novel GH38 α-mannosidase from the crenarchaeon Sulfolobus solfataricus revealed its ability in de-mannosylating glycoproteins.

Cobucci-Ponzano B, Conte F, Strazzulli A, Capasso C, Fiume I, Pocsfalvi G, Rossi M, Moracci M.

Biochimie. 2010 Dec;92(12):1895-907. doi: 10.1016/j.biochi.2010.07.016. Epub 2010 Aug 7.

PMID:
20696204
24.

A new archaeal beta-glycosidase from Sulfolobus solfataricus: seeding a novel retaining beta-glycan-specific glycoside hydrolase family along with the human non-lysosomal glucosylceramidase GBA2.

Cobucci-Ponzano B, Aurilia V, Riccio G, Henrissat B, Coutinho PM, Strazzulli A, Padula A, Corsaro MM, Pieretti G, Pocsfalvi G, Fiume I, Cannio R, Rossi M, Moracci M.

J Biol Chem. 2010 Jul 2;285(27):20691-703. doi: 10.1074/jbc.M109.086470. Epub 2010 Apr 28.

25.

Functional characterization and high-throughput proteomic analysis of interrupted genes in the archaeon Sulfolobus solfataricus.

Cobucci-Ponzano B, Guzzini L, Benelli D, Londei P, Perrodou E, Lecompte O, Tran D, Sun J, Wei J, Mathur EJ, Rossi M, Moracci M.

J Proteome Res. 2010 May 7;9(5):2496-507. doi: 10.1021/pr901166q.

PMID:
20192274
26.

beta-Glycosyl azides as substrates for alpha-glycosynthases: preparation of efficient alpha-L-fucosynthases.

Cobucci-Ponzano B, Conte F, Bedini E, Corsaro MM, Parrilli M, Sulzenbacher G, Lipski A, Dal Piaz F, Lepore L, Rossi M, Moracci M.

Chem Biol. 2009 Oct 30;16(10):1097-108. doi: 10.1016/j.chembiol.2009.09.013.

27.

Evidence that the xylanase activity from Sulfolobus solfataricus Oalpha is encoded by the endoglucanase precursor gene (sso1354) and characterization of the associated cellulase activity.

Maurelli L, Giovane A, Esposito A, Moracci M, Fiume I, Rossi M, Morana A.

Extremophiles. 2008 Sep;12(5):689-700. doi: 10.1007/s00792-008-0175-5. Epub 2008 Jun 21.

PMID:
18568289
28.

Isolation and characterization of a new family 42 beta-galactosidase from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius: identification of the active site residues.

Di Lauro B, Strazzulli A, Perugino G, La Cara F, Bedini E, Corsaro MM, Rossi M, Moracci M.

Biochim Biophys Acta. 2008 Feb;1784(2):292-301. Epub 2007 Nov 12.

PMID:
18068682
29.

The alpha-L-fucosidase from Sulfolobus solfataricus.

Cobucci-Ponzano B, Conte F, Rossi M, Moracci M.

Extremophiles. 2008 Jan;12(1):61-8. Epub 2007 Aug 9. Review.

PMID:
17687508
30.

A comparative infrared spectroscopic study of glycoside hydrolases from extremophilic archaea revealed different molecular mechanisms of adaptation to high temperatures.

Ausili A, Cobucci-Ponzano B, Di Lauro B, D'Avino R, Perugino G, Bertoli E, Scirè A, Rossi M, Tanfani F, Moracci M.

Proteins. 2007 Jun 1;67(4):991-1001.

PMID:
17357157
31.

Interrupted genes in extremophilic archaea: mechanisms of gene expression in early organisms.

Cobucci-Ponzano B, Rossi M, Moracci M.

Orig Life Evol Biosph. 2006 Dec;36(5-6):487-92. Review.

PMID:
17120127
32.

Structural, kinetic, and thermodynamic analysis of glucoimidazole-derived glycosidase inhibitors.

Gloster TM, Roberts S, Perugino G, Rossi M, Moracci M, Panday N, Terinek M, Vasella A, Davies GJ.

Biochemistry. 2006 Oct 3;45(39):11879-84.

PMID:
17002288
33.

The gene of an archaeal alpha-L-fucosidase is expressed by translational frameshifting.

Cobucci-Ponzano B, Conte F, Benelli D, Londei P, Flagiello A, Monti M, Pucci P, Rossi M, Moracci M.

Nucleic Acids Res. 2006;34(15):4258-68. Epub 2006 Aug 18.

34.

Characterization of a beta-glycosidase from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius.

Di Lauro B, Rossi M, Moracci M.

Extremophiles. 2006 Aug;10(4):301-10. Epub 2006 Apr 12. Erratum in: Extremophiles. 2008 Mar;12(2):309.

PMID:
16609814
35.

Structural basis of the destabilization produced by an amino-terminal tag in the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus.

Ausili A, Cobucci-Ponzano B, Di Lauro B, D'Avino R, Scirè A, Rossi M, Tanfani F, Moracci M.

Biochimie. 2006 Jul;88(7):807-17. Epub 2006 Feb 9.

PMID:
16494988
36.

Highly productive autocondensation and transglycosylation reactions with Sulfolobus solfataricus glycosynthase.

Trincone A, Giordano A, Perugino G, Rossi M, Moracci M.

Chembiochem. 2005 Aug;6(8):1431-7.

PMID:
16010696
37.

Probing the catalytically essential residues of the alpha-L-fucosidase from the hyperthermophilic archaeon Sulfolobus solfataricus.

Cobucci-Ponzano B, Mazzone M, Rossi M, Moracci M.

Biochemistry. 2005 Apr 26;44(16):6331-42.

PMID:
15835922
38.

A novel fatty acid binding protein produced by teratocytes of the aphid parasitoid Aphidius ervi.

Falabella P, Perugino G, Caccialupi P, Riviello L, Varricchio P, Tranfaglia A, Rossi M, Malva C, Graziani F, Moracci M, Pennacchio F.

Insect Mol Biol. 2005 Apr;14(2):195-205.

PMID:
15796753
39.

Recoding in archaea.

Cobucci-Ponzano B, Rossi M, Moracci M.

Mol Microbiol. 2005 Jan;55(2):339-48. Review.

41.

Structural characterization of the nonameric assembly of an Archaeal alpha-L-fucosidase by synchrotron small angle X-ray scattering.

Rosano C, Zuccotti S, Cobucci-Ponzano B, Mazzone M, Rossi M, Moracci M, Petoukhov MV, Svergun DI, Bolognesi M.

Biochem Biophys Res Commun. 2004 Jul 16;320(1):176-82.

PMID:
15207718
42.

Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.

Gloster TM, Roberts S, Ducros VM, Perugino G, Rossi M, Hoos R, Moracci M, Vasella A, Davies GJ.

Biochemistry. 2004 May 25;43(20):6101-9.

PMID:
15147194
43.

Oligosaccharide synthesis by glycosynthases.

Perugino G, Trincone A, Rossi M, Moracci M.

Trends Biotechnol. 2004 Jan;22(1):31-7. Review. No abstract available.

PMID:
14690620
44.

Glycosynthase-catalysed syntheses at pH below neutrality.

Trincone A, Giordano A, Perugino G, Rossi M, Moracci M.

Bioorg Med Chem Lett. 2003 Nov 17;13(22):4039-42.

PMID:
14592503
45.

Identification of the catalytic nucleophile of the family 29 alpha-L-fucosidase from Sulfolobus solfataricus via chemical rescue of an inactive mutant.

Cobucci-Ponzano B, Trincone A, Giordano A, Rossi M, Moracci M.

Biochemistry. 2003 Aug 19;42(32):9525-31.

PMID:
12911294
46.

Activity of hyperthermophilic glycosynthases is significantly enhanced at acidic pH.

Perugino G, Trincone A, Giordano A, van der Oost J, Kaper T, Rossi M, Moracci M.

Biochemistry. 2003 Jul 22;42(28):8484-93.

PMID:
12859194
47.

Extremophiles 2002.

Rossi M, Ciaramella M, Cannio R, Pisani FM, Moracci M, Bartolucci S.

J Bacteriol. 2003 Jul;185(13):3683-9. No abstract available.

48.

Identification of an archaeal alpha-L-fucosidase encoded by an interrupted gene. Production of a functional enzyme by mutations mimicking programmed -1 frameshifting.

Cobucci-Ponzano B, Trincone A, Giordano A, Rossi M, Moracci M.

J Biol Chem. 2003 Apr 25;278(17):14622-31. Epub 2003 Feb 4.

49.
50.

Enzymatic synthesis and hydrolysis of xylogluco-oligosaccharides using the first archaeal alpha-xylosidase from Sulfolobus solfataricus.

Trincone A, Cobucci-Ponzano B, Di Lauro B, Rossi M, Mitsuishi Y, Moracci M.

Extremophiles. 2001 Aug;5(4):277-82.

PMID:
11523897

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