Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 89

1.

An open-label phase 1 clinical trial of the anti-α4β7 monoclonal antibody vedolizumab in HIV-infected individuals.

Sneller MC, Clarridge KE, Seamon C, Shi V, Zorawski MD, Justement JS, Blazkova J, Huiting ED, Proschan MA, Mora JR, Shetzline M, Moir S, Lane HC, Chun TW, Fauci AS.

Sci Transl Med. 2019 Sep 11;11(509). pii: eaax3447. doi: 10.1126/scitranslmed.aax3447. Epub 2019 Sep 5.

PMID:
31488581
2.

A negative role for the interleukin-2-inducible T-cell kinase (ITK) in human Foxp3+ TREG differentiation.

Mamontov P, Eberwine RA, Perrigoue J, Das A, Friedman JR, Mora JR.

PLoS One. 2019 Apr 25;14(4):e0215963. doi: 10.1371/journal.pone.0215963. eCollection 2019.

3.

Differences in expression rather than methylation at placenta-specific imprinted loci is associated with intrauterine growth restriction.

Monteagudo-Sánchez A, Sánchez-Delgado M, Mora JRH, Santamaría NT, Gratacós E, Esteller M, de Heredia ML, Nunes V, Choux C, Fauque P, de Nanclares GP, Anton L, Elovitz MA, Iglesias-Platas I, Monk D.

Clin Epigenetics. 2019 Feb 26;11(1):35. doi: 10.1186/s13148-019-0630-4.

4.

Correction: Intestinal epithelial cell-specific RARα depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system.

Jijon HB, Suarez-Lopez L, Diaz OE, Das S, De Calisto J, Parada-Kusz M, Yaffe MB, Pittet MJ, Mora JR, Belkaid Y, Xavier RJ, Villablanca EJ.

Mucosal Immunol. 2019 Mar;12(2):580. doi: 10.1038/s41385-018-0074-8.

PMID:
30514887
5.

Classical QSAR and Docking Simulation of 4-Pyridone Derivatives for Their Antimalarial Activity.

Flores-Sumoza M, Alcázar JJ, Márquez E, Mora JR, Lezama J, Puello E.

Molecules. 2018 Dec 1;23(12). pii: E3166. doi: 10.3390/molecules23123166.

6.

Theoretical investigation of the mechanism for the reductive dehalogenation of methyl halides mediated by the CoI-based compounds cobalamin and cobaloxime.

Terán JE, Zambrano CH, Mora JR, Rincón L, Torres FJ.

J Mol Model. 2018 Oct 18;24(11):316. doi: 10.1007/s00894-018-3844-z.

PMID:
30338391
7.

T follicular helper cells restricted by IRF8 contribute to T cell-mediated inflammation.

Zhang R, Qi CF, Hu Y, Shan Y, Hsieh YP, Xu F, Lu G, Dai J, Gupta M, Cui M, Peng L, Yang J, Xue Q, Chen-Liang R, Chen K, Zhang Y, Fung-Leung WP, Mora JR, Li L, Morse HC 3rd, Ozato K, Heeger PS, Xiong H.

J Autoimmun. 2019 Jan;96:113-122. doi: 10.1016/j.jaut.2018.09.001. Epub 2018 Sep 19.

PMID:
30241692
8.

New Insight into the Chloroacetanilide Herbicide Degradation Mechanism through a Nucleophilic Attack of Hydrogen Sulfide.

Mora JR, Cervantes C, Marquez E.

Int J Mol Sci. 2018 Sep 21;19(10). pii: E2864. doi: 10.3390/ijms19102864.

9.

β7 integrins contribute to intestinal tumor growth in mice.

Das S, Doñas C, Akeus P, Quiding-Järbrink M, Mora JR, Villablanca EJ.

PLoS One. 2018 Sep 20;13(9):e0204181. doi: 10.1371/journal.pone.0204181. eCollection 2018.

10.

Generic Anti-PEG Antibody Assay on ProterixBio's (Formerly BioScale) ViBE Platform Shows Poor Reproducibility.

Chilewski SD, Shields J, Mora JR, Myler H.

AAPS J. 2018 Apr 24;20(3):65. doi: 10.1208/s12248-018-0228-3.

PMID:
29691672
11.

Intestinal epithelial cell-specific RARα depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system.

Jijon HB, Suarez-Lopez L, Diaz OE, Das S, De Calisto J, Parada-kusz M, Yaffe MB, Pittet MJ, Mora JR, Belkaid Y, Xavier RJ, Villablanca EJ.

Mucosal Immunol. 2018 May;11(3):703-715. doi: 10.1038/mi.2017.91. Epub 2017 Nov 15. Erratum in: Mucosal Immunol. 2019 Mar;12(2):580. Parada-kusz, M [added].

12.

Theoretical analysis of C-F bond cleavage mediated by cob[I]alamin-based structures.

Cortés-Arriagada D, Toro-Labbe A, Mora JR, Rincón L, Mereau R, Torres FJ.

J Mol Model. 2017 Aug 17;23(9):264. doi: 10.1007/s00894-017-3431-8.

PMID:
28819880
13.

A deletion affecting an LRR-RLK gene co-segregates with the fruit flat shape trait in peach.

López-Girona E, Zhang Y, Eduardo I, Mora JRH, Alexiou KG, Arús P, Aranzana MJ.

Sci Rep. 2017 Jul 27;7(1):6714. doi: 10.1038/s41598-017-07022-0.

14.

A DFT study of hydrogen and methane activation by B(C6F5)3/P(t-Bu)3 and Al(C6F5)3/P(t-Bu)3 frustrated Lewis pairs.

Villegas-Escobar N, Toro-Labbé A, Becerra M, Real-Enriquez M, Mora JR, Rincon L.

J Mol Model. 2017 Aug;23(8):234. doi: 10.1007/s00894-017-3404-y. Epub 2017 Jul 21.

PMID:
28733881
15.

Transforming a Stable Amide into a Highly Reactive One: Capturing the Essence of Enzymatic Catalysis.

Souza BS, Mora JR, Wanderlind EH, Clementin RM, Gesser JC, Fiedler HD, Nome F, Menger FM.

Angew Chem Int Ed Engl. 2017 May 2;56(19):5345-5348. doi: 10.1002/anie.201701306. Epub 2017 Apr 5.

PMID:
28378430
16.

β8 Integrin Expression and Activation of TGF-β by Intestinal Dendritic Cells Are Determined by Both Tissue Microenvironment and Cell Lineage.

Boucard-Jourdin M, Kugler D, Endale Ahanda ML, This S, De Calisto J, Zhang A, Mora JR, Stuart LM, Savill J, Lacy-Hulbert A, Paidassi H.

J Immunol. 2016 Sep 1;197(5):1968-78. doi: 10.4049/jimmunol.1600244. Epub 2016 Aug 1.

17.

Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects.

Rigoni R, Fontana E, Guglielmetti S, Fosso B, D'Erchia AM, Maina V, Taverniti V, Castiello MC, Mantero S, Pacchiana G, Musio S, Pedotti R, Selmi C, Mora JR, Pesole G, Vezzoni P, Poliani PL, Grassi F, Villa A, Cassani B.

J Exp Med. 2016 Mar 7;213(3):355-75. doi: 10.1084/jem.20151116. Epub 2016 Feb 29.

18.

Vitamin A Impairs the Reprogramming of Tregs into IL-17-Producing Cells during Intestinal Inflammation.

Tejón G, Manríquez V, De Calisto J, Flores-Santibáñez F, Hidalgo Y, Crisóstomo N, Fernández D, Sauma D, Mora JR, Bono MR, Rosemblatt M.

Biomed Res Int. 2015;2015:137893. doi: 10.1155/2015/137893. Epub 2015 Oct 25.

19.

Development of a Generic Anti-PEG Antibody Assay Using BioScale's Acoustic Membrane MicroParticle Technology.

Dong H, Mora JR, Brockus C, Chilewski SD, Dodge R, Merrifield C, Dickerson WM, DeSilva B.

AAPS J. 2015 Nov;17(6):1511-6. doi: 10.1208/s12248-015-9799-4. Epub 2015 Jul 3.

20.

[Inverse innovation models in the nurse clinic of a Urology Department].

Gamarra M, López MC, Luján M, Mora JR.

Arch Esp Urol. 2015 Jan-Feb;68(1):115-24. Spanish.

PMID:
25688537
21.

[Definition and stabilization of processes II. Clinical Processes in a Urology Department].

Pascual C, Luján M, Mora JR, Diz MR, Martín C, López MC.

Arch Esp Urol. 2015 Jan-Feb;68(1):80-95. Spanish.

PMID:
25688534
22.

[Definition and stabilization of processes I. Management processes and support in a Urology Department].

Pascual C, Luján M, Mora JR, Chiva V, Gamarra M.

Arch Esp Urol. 2015 Jan-Feb;68(1):71-9. Spanish.

PMID:
25688533
23.

[Architecture and design of a processes map in a Urology Department].

Mora JR, Luján M.

Arch Esp Urol. 2015 Jan-Feb;68(1):56-70. Spanish.

PMID:
25688532
24.

[Methodology for process documentation and stabilization].

Mora JR.

Arch Esp Urol. 2015 Jan-Feb;68(1):36-54. Spanish.

PMID:
25688531
25.

[Evaluation of the maturity of a Urology Department in terms of Quality. Management and Quality improvement operative objectives].

Luján M, Mora JR, Pascual C, Chiva V, Diz MR, Martín C, Gamarra M, del Carmen López M.

Arch Esp Urol. 2015 Jan-Feb;68(1):23-35. Spanish.

PMID:
25688530
26.

[What does Process Management add in a Urology Department?].

Luján M, Mora JR.

Arch Esp Urol. 2015 Jan-Feb;68(1):1-4. Spanish.

PMID:
25688527
27.

SLAMF4 Is a Negative Regulator of Expansion of Cytotoxic Intraepithelial CD8+ T Cells That Maintains Homeostasis in the Small Intestine.

O'Keeffe MS, Song JH, Liao G, De Calisto J, Halibozek PJ, Mora JR, Bhan AK, Wang N, Reinecker HC, Terhorst C.

Gastroenterology. 2015 May;148(5):991-1001.e4. doi: 10.1053/j.gastro.2015.02.003. Epub 2015 Feb 10.

28.

Chiari malformation type I with cervicothoracic syringomyelia masquerading as bibrachial amyotrophy: a case report.

Mora JR, Rison RA, Beydoun SR.

J Med Case Rep. 2015 Jan 27;9:11. doi: 10.1186/1752-1947-9-11.

29.

Evaluation of acoustic membrane microparticle (AMMP) technology for a sensitive ligand binding assay to support pharmacokinetic determinations of a biotherapeutic.

Chilewski SD, Dickerson WM, Mora JR, Saab A, Alderman EM.

AAPS J. 2014 Nov;16(6):1366-71. doi: 10.1208/s12248-014-9659-7. Epub 2014 Sep 23.

30.

Interplay of nutrients and microbial metabolites in intestinal immune homeostasis: distinct and common mechanisms of immune regulation in the small bowel and colon.

Perrigoue J, Das A, Mora JR.

Nestle Nutr Inst Workshop Ser. 2014;79:57-71. doi: 10.1159/000360685. Epub 2014 Sep 5.

PMID:
25227295
31.

Addressing matrix effects in ligand-binding assays through the use of new reagents and technology.

Chilewski SD, Mora JR, Gleason C, DeSilva B.

Bioanalysis. 2014 Apr;6(8):1059-67. doi: 10.4155/bio.14.75.

PMID:
24830890
32.

Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function.

Shouval DS, Biswas A, Goettel JA, McCann K, Conaway E, Redhu NS, Mascanfroni ID, Al Adham Z, Lavoie S, Ibourk M, Nguyen DD, Samsom JN, Escher JC, Somech R, Weiss B, Beier R, Conklin LS, Ebens CL, Santos FG, Ferreira AR, Sherlock M, Bhan AK, Müller W, Mora JR, Quintana FJ, Klein C, Muise AM, Horwitz BH, Snapper SB.

Immunity. 2014 May 15;40(5):706-19. doi: 10.1016/j.immuni.2014.03.011. Epub 2014 May 1.

33.

Outpatient urologic surgery office conducted by nursing staff. A process integrated in a total quality strategy.

Lujan M, Gamarra M, Mora JR, Lopez MC, Pascual C, Martin C, Diz MR, Chiva V.

Arch Esp Urol. 2013 Nov;66(9):841-50. English, Spanish.

PMID:
24231294
34.

β7 integrins are required to give rise to intestinal mononuclear phagocytes with tolerogenic potential.

Villablanca EJ, De Calisto J, Torregrosa Paredes P, Cassani B, Nguyen DD, Gabrielsson S, Mora JR.

Gut. 2014 Sep;63(9):1431-40. doi: 10.1136/gutjnl-2013-305386. Epub 2013 Sep 12.

PMID:
24030488
35.

Major mechanistic differences between the reactions of hydroxylamine with phosphate di- and tri-esters.

Medeiros M, Wanderlind EH, Mora JR, Moreira R, Kirby AJ, Nome F.

Org Biomol Chem. 2013 Oct 7;11(37):6272-84. doi: 10.1039/c3ob40988k.

PMID:
23900489
36.

The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils.

Raccosta L, Fontana R, Maggioni D, Lanterna C, Villablanca EJ, Paniccia A, Musumeci A, Chiricozzi E, Trincavelli ML, Daniele S, Martini C, Gustafsson JA, Doglioni C, Feo SG, Leiva A, Ciampa MG, Mauri L, Sensi C, Prinetti A, Eberini I, Mora JR, Bordignon C, Steffensen KR, Sonnino S, Sozzani S, Traversari C, Russo V.

J Exp Med. 2013 Aug 26;210(9):1711-28. doi: 10.1084/jem.20130440. Epub 2013 Jul 29.

37.

Intramolecular general base catalysis in the hydrolysis of a phosphate diester. Calculational guidance to a choice of mechanism.

Kirby AJ, Medeiros M, Mora JR, Oliveira PS, Amer A, Williams NH, Nome F.

J Org Chem. 2013 Feb 15;78(4):1343-53. doi: 10.1021/jo302498g. Epub 2013 Feb 7.

PMID:
23373989
38.

FcγRI (CD64): an identity card for intestinal macrophages.

De Calisto J, Villablanca EJ, Mora JR.

Eur J Immunol. 2012 Dec;42(12):3136-40. doi: 10.1002/eji.201243061.

39.

Surface charge of zwitterionic sulfobetaine micelles with 2-naphthol as a fluorescent probe.

Pedro JA, Mora JR, Silva M, Fiedler HD, Bunton CA, Nome F.

Langmuir. 2012 Dec 21;28(51):17623-31. doi: 10.1021/la303880m. Epub 2012 Dec 11.

PMID:
23194176
40.
41.

Theoretical study of the importance of the spectator groups on the hydrolysis of phosphate triesters.

Mora JR, Kirby AJ, Nome F.

J Org Chem. 2012 Aug 17;77(16):7061-70. doi: 10.1021/jo301380v. Epub 2012 Aug 3.

PMID:
22835036
42.

Gut immune maturation depends on colonization with a host-specific microbiota.

Chung H, Pamp SJ, Hill JA, Surana NK, Edelman SM, Troy EB, Reading NC, Villablanca EJ, Wang S, Mora JR, Umesaki Y, Mathis D, Benoist C, Relman DA, Kasper DL.

Cell. 2012 Jun 22;149(7):1578-93. doi: 10.1016/j.cell.2012.04.037.

43.

Wiskott-Aldrich syndrome protein deficiency in innate immune cells leads to mucosal immune dysregulation and colitis in mice.

Nguyen DD, Wurbel MA, Goettel JA, Eston MA, Ahmed OS, Marin R, Boden EK, Villablanca EJ, Paidassi H, Ahuja V, Reinecker HC, Fiebiger E, Lacy-Hulbert A, Horwitz BH, Mora JR, Snapper SB.

Gastroenterology. 2012 Sep;143(3):719-729.e2. doi: 10.1053/j.gastro.2012.06.008. Epub 2012 Jun 15.

44.

New light on phosphate transfer from triesters.

Kirby AJ, Mora JR, Nome F.

Biochim Biophys Acta. 2013 Jan;1834(1):454-63. doi: 10.1016/j.bbapap.2012.04.010. Epub 2012 May 2. Review.

45.

Chitin microparticles for the control of intestinal inflammation.

Nagatani K, Wang S, Llado V, Lau CW, Li Z, Mizoguchi A, Nagler CR, Shibata Y, Reinecker HC, Mora JR, Mizoguchi E.

Inflamm Bowel Dis. 2012 Sep;18(9):1698-710. doi: 10.1002/ibd.22874. Epub 2012 Jan 12.

46.

Kinetics and mechanisms of the unimolecular elimination of 2,2-diethoxypropane and 1,1-diethoxycyclohexane in the gas phase: experimental and theoretical study.

Rosas F, Maldonado A, Lezama J, Domínguez RM, Mora JR, Cordova T, Chuchani G.

J Phys Chem A. 2012 Jan 19;116(2):846-54. doi: 10.1021/jp209596p. Epub 2012 Jan 6.

PMID:
22185116
47.

Vitamin A and immune regulation: role of retinoic acid in gut-associated dendritic cell education, immune protection and tolerance.

Cassani B, Villablanca EJ, De Calisto J, Wang S, Mora JR.

Mol Aspects Med. 2012 Feb;33(1):63-76. doi: 10.1016/j.mam.2011.11.001. Epub 2011 Nov 22. Review.

48.

Gut-tropic T cells that express integrin α4β7 and CCR9 are required for induction of oral immune tolerance in mice.

Cassani B, Villablanca EJ, Quintana FJ, Love PE, Lacy-Hulbert A, Blaner WS, Sparwasser T, Snapper SB, Weiner HL, Mora JR.

Gastroenterology. 2011 Dec;141(6):2109-18. doi: 10.1053/j.gastro.2011.09.015. Epub 2011 Sep 16.

49.

T-cell homing to the gut mucosa: general concepts and methodological considerations.

De Calisto J, Villablanca EJ, Wang S, Bono MR, Rosemblatt M, Mora JR.

Methods Mol Biol. 2012;757:411-34. doi: 10.1007/978-1-61779-166-6_24.

PMID:
21909925
50.

Vitamin A deficiency impairs vaccine-elicited gastrointestinal immunity.

Kaufman DR, De Calisto J, Simmons NL, Cruz AN, Villablanca EJ, Mora JR, Barouch DH.

J Immunol. 2011 Aug 15;187(4):1877-83. doi: 10.4049/jimmunol.1101248. Epub 2011 Jul 15.

Supplemental Content

Support Center