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Items: 45

1.

Cysteine auxotrophy drives reduced susceptibility to quinolones and paraquat by inducing the expression of efflux-pump systems and detoxifying enzymes in S. Typhimurium.

Villagra NA, Valenzuela LM, Mora AY, Millanao AR, Saavedra CP, Mora GC, Hidalgo AA.

Biochem Biophys Res Commun. 2019 Jul 23;515(2):339-344. doi: 10.1016/j.bbrc.2019.05.122. Epub 2019 May 29.

PMID:
31151825
2.

Xylose Improves Antibiotic Activity of Chloramphenicol and Tetracycline against K. pneumoniae and A. baumannii in a Murine Model of Skin Infection.

Hidalgo AA, Arias ÁJ, Fuentes JA, García P, Mora GC, Villagra NA.

Can J Infect Dis Med Microbiol. 2018 Jul 18;2018:3467219. doi: 10.1155/2018/3467219. eCollection 2018.

3.

Lose to win: marT pseudogenization in Salmonella enterica serovar Typhi contributed to the surV-dependent survival to H2O2, and inside human macrophage-like cells.

Ortega AP, Villagra NA, Urrutia IM, Valenzuela LM, Talamilla-Espinoza A, Hidalgo AA, Rodas PI, Gil F, Calderón IL, Paredes-Sabja D, Mora GC, Fuentes JA.

Infect Genet Evol. 2016 Nov;45:111-121. doi: 10.1016/j.meegid.2016.08.029. Epub 2016 Aug 24.

PMID:
27567490
4.

SPI-9 of Salmonella enterica serovar Typhi is constituted by an operon positively regulated by RpoS and contributes to adherence to epithelial cells in culture.

Velásquez JC, Hidalgo AA, Villagra N, Santiviago CA, Mora GC, Fuentes JA.

Microbiology. 2016 Aug;162(8):1367-78. doi: 10.1099/mic.0.000319. Epub 2016 Jun 3.

PMID:
27260307
5.

A conditionally lethal mutant of Salmonella Typhimurium induces a protective response in mice.

Hidalgo AA, Villagra NA, Jerez SA, Fuentes JA, Mora GC.

Biochem Biophys Res Commun. 2016 Feb 5;470(2):313-318. doi: 10.1016/j.bbrc.2016.01.058. Epub 2016 Jan 11.

PMID:
26792728
6.

stg fimbrial operon from S. Typhi STH2370 contributes to association and cell disruption of epithelial and macrophage-like cells.

Berrocal L, Fuentes JA, Trombert AN, Jofré MR, Villagra NA, Valenzuela LM, Mora GC.

Biol Res. 2015 Jul 7;48:34. doi: 10.1186/s40659-015-0024-9.

7.

Pseudogenization of sopA and sopE2 is functionally linked and contributes to virulence of Salmonella enterica serovar Typhi.

Valenzuela LM, Hidalgo AA, Rodríguez L, Urrutia IM, Ortega AP, Villagra NA, Paredes-Sabja D, Calderón IL, Gil F, Saavedra CP, Mora GC, Fuentes JA.

Infect Genet Evol. 2015 Jul;33:131-42. doi: 10.1016/j.meegid.2015.04.021. Epub 2015 Apr 23.

PMID:
25913156
8.

RpoS integrates CRP, Fis, and PhoP signaling pathways to control Salmonella Typhi hlyE expression.

Jofré MR, Rodríguez LM, Villagra NA, Hidalgo AA, Mora GC, Fuentes JA.

BMC Microbiol. 2014 May 31;14:139. doi: 10.1186/1471-2180-14-139.

9.

Salmonella Typhi shdA: pseudogene or allelic variant?

Urrutia IM, Fuentes JA, Valenzuela LM, Ortega AP, Hidalgo AA, Mora GC.

Infect Genet Evol. 2014 Aug;26:146-52. doi: 10.1016/j.meegid.2014.05.013. Epub 2014 May 21.

PMID:
24859062
10.

Draft Genome Sequence of Salmonella enterica Serovar Typhi Strain STH2370.

Valenzuela C, Ugalde JA, Mora GC, Alvarez S, Contreras I, Santiviago CA.

Genome Announc. 2014 Feb 20;2(1). pii: e00104-14. doi: 10.1128/genomeA.00104-14.

11.

Porin alterations present in non-carbapenemase-producing Enterobacteriaceae with high and intermediate levels of carbapenem resistance in Chile.

Wozniak A, Villagra NA, Undabarrena A, Gallardo N, Keller N, Moraga M, Román JC, Mora GC, García P.

J Med Microbiol. 2012 Sep;61(Pt 9):1270-9. doi: 10.1099/jmm.0.045799-0. Epub 2012 Jun 14.

PMID:
22700549
12.

The carbon source influences the efflux pump-mediated antimicrobial resistance in clinically important Gram-negative bacteria.

Villagra NA, Fuentes JA, Jofré MR, Hidalgo AA, García P, Mora GC.

J Antimicrob Chemother. 2012 Apr;67(4):921-7. doi: 10.1093/jac/dkr573. Epub 2012 Jan 17.

PMID:
22258924
13.

Reduced invasion to human epithelial cell lines of Salmonella enterica serovar Typhi carrying S. Typhimurium sopD2.

Trombert AN, Rodas PI, Mora GC.

FEMS Microbiol Lett. 2011 Sep;322(2):150-6. doi: 10.1111/j.1574-6968.2011.02347.x. Epub 2011 Aug 1.

14.

A holin remnant protein encoded by STY1365 is involved in envelope stability of Salmonella enterica serovar Typhi.

Rodas PI, Trombert AN, Mora GC.

FEMS Microbiol Lett. 2011 Aug;321(1):58-66. doi: 10.1111/j.1574-6968.2011.02310.x. Epub 2011 Jun 6.

15.

Response regulator ArcA of Salmonella enterica serovar Typhimurium downregulates expression of OmpD, a porin facilitating uptake of hydrogen peroxide.

Calderón IL, Morales E, Caro NJ, Chahúan CA, Collao B, Gil F, Villarreal JM, Ipinza F, Mora GC, Saavedra CP.

Res Microbiol. 2011 Feb-Mar;162(2):214-22. doi: 10.1016/j.resmic.2010.11.001. Epub 2010 Dec 7.

PMID:
21144897
16.

S. Typhimurium sseJ gene decreases the S. Typhi cytotoxicity toward cultured epithelial cells.

Trombert AN, Berrocal L, Fuentes JA, Mora GC.

BMC Microbiol. 2010 Dec 7;10:312. doi: 10.1186/1471-2180-10-312.

17.

Salmonella enterica serovar Typhi has a 4.1 kb genetic island inserted within the sapABCDF operon that causes loss of resistance to the antimicrobial peptide protamine.

Rodas PI, Contreras I, Mora GC.

J Antimicrob Chemother. 2010 Aug;65(8):1624-30. doi: 10.1093/jac/dkq197. Epub 2010 Jun 15.

PMID:
20551214
18.

Modified intracellular-associated phenotypes in a recombinant Salmonella Typhi expressing S. Typhimurium SPI-3 sequences.

Retamal P, Castillo-Ruiz M, Villagra NA, Morgado J, Mora GC.

PLoS One. 2010 Feb 24;5(2):e9394. doi: 10.1371/journal.pone.0009394.

19.

RpoS- and Crp-dependent transcriptional control of Salmonella Typhi taiA and hlyE genes: role of environmental conditions.

Fuentes JA, Jofré MR, Villagra NA, Mora GC.

Res Microbiol. 2009 Dec;160(10):800-8. doi: 10.1016/j.resmic.2009.09.016. Epub 2009 Oct 14.

PMID:
19835951
20.

Characterization of MgtC, a virulence factor of Salmonella enterica Serovar Typhi.

Retamal P, Castillo-Ruiz M, Mora GC.

PLoS One. 2009;4(5):e5551. doi: 10.1371/journal.pone.0005551. Epub 2009 May 14.

21.

SmvA, and not AcrB, is the major efflux pump for acriflavine and related compounds in Salmonella enterica serovar Typhimurium.

Villagra NA, Hidalgo AA, Santiviago CA, Saavedra CP, Mora GC.

J Antimicrob Chemother. 2008 Dec;62(6):1273-6. doi: 10.1093/jac/dkn407. Epub 2008 Sep 26.

PMID:
18819967
22.

The Salmonella Typhi hlyE gene plays a role in invasion of cultured epithelial cells and its functional transfer to S. Typhimurium promotes deep organ infection in mice.

Fuentes JA, Villagra N, Castillo-Ruiz M, Mora GC.

Res Microbiol. 2008 May;159(4):279-87. doi: 10.1016/j.resmic.2008.02.006. Epub 2008 Mar 16.

PMID:
18434098
23.

The capacity of Salmonella to survive inside dendritic cells and prevent antigen presentation to T cells is host specific.

Bueno SM, González PA, Carreño LJ, Tobar JA, Mora GC, Pereda CJ, Salazar-Onfray F, Kalergis AM.

Immunology. 2008 Aug;124(4):522-33. doi: 10.1111/j.1365-2567.2008.02805.x. Epub 2008 Feb 8.

24.

The ompW (porin) gene mediates methyl viologen (paraquat) efflux in Salmonella enterica serovar typhimurium.

Gil F, Ipinza F, Fuentes J, Fumeron R, Villarreal JM, Aspée A, Mora GC, Vásquez CC, Saavedra C.

Res Microbiol. 2007 Jul-Aug;158(6):529-36. Epub 2007 May 27.

PMID:
17618087
25.

The cotranscribed Salmonella enterica sv. Typhi tsx and impX genes encode opposing nucleoside-specific import and export proteins.

Bucarey SA, Villagra NA, Fuentes JA, Mora GC.

Genetics. 2006 May;173(1):25-34. Epub 2006 Feb 19.

26.

The Salmonella enterica serovar Typhi tsx gene, encoding a nucleoside-specific porin, is essential for prototrophic growth in the absence of nucleosides.

Bucarey SA, Villagra NA, Martinic MP, Trombert AN, Santiviago CA, Maulén NP, Youderian P, Mora GC.

Infect Immun. 2005 Oct;73(10):6210-9.

27.

The product of the qacC gene of Staphylococcus epidermidis CH mediates resistance to beta-lactam antibiotics in gram-positive and gram-negative bacteria.

Fuentes DE, Navarro CA, Tantaleán JC, Araya MA, Saavedra CP, Pérez JM, Calderón IL, Youderian PA, Mora GC, Vásquez CC.

Res Microbiol. 2005 May;156(4):472-7. Epub 2005 Feb 19.

PMID:
15862444
28.

Genetic analysis of antibiotic-resistance determinants in multidrug-resistant Shigella strains isolated from Chilean children.

Toro CS, Farfán M, Contreras I, Flores O, Navarro N, Mora GC, Prado V.

Epidemiol Infect. 2005 Feb;133(1):81-6.

29.

Insertions of mini-Tn10 transposon T-POP in Salmonella enterica sv. typhi.

Hidalgo AA, Trombert AN, Castro-Alonso JC, Santiviago CA, Tesser BR, Youderian P, Mora GC.

Genetics. 2004 Jul;167(3):1069-77.

30.

Precise excision of the large pathogenicity island, SPI7, in Salmonella enterica serovar Typhi.

Bueno SM, Santiviago CA, Murillo AA, Fuentes JA, Trombert AN, Rodas PI, Youderian P, Mora GC.

J Bacteriol. 2004 May;186(10):3202-13.

31.

Global regulation of the Salmonella enterica serovar typhimurium major porin, OmpD.

Santiviago CA, Toro CS, Hidalgo AA, Youderian P, Mora GC.

J Bacteriol. 2003 Oct;185(19):5901-5.

32.

The Salmonella enterica sv. Typhimurium smvA, yddG and ompD (porin) genes are required for the efficient efflux of methyl viologen.

Santiviago CA, Fuentes JA, Bueno SM, Trombert AN, Hildago AA, Socias LT, Youderian P, Mora GC.

Mol Microbiol. 2002 Nov;46(3):687-98.

33.
34.
35.

Salmonella typhi mutants defective in anaerobic respiration are impaired in their ability to replicate within epithelial cells.

Contreras I, Toro CS, Troncoso G, Mora GC.

Microbiology. 1997 Aug;143 ( Pt 8):2665-72.

PMID:
9274020
36.

Salmonella typhi Ty2 OmpC porin induces bactericidal activity on U937 monocytes.

Blanco LP, Toro CS, Romero JM, Santiviago CA, Mora GC.

Microbiol Immunol. 1997;41(12):999-1003.

37.
39.

Mini-Mu technology in Salmonella typhi: isolation of stable MudJ operon fusions by cis complementation.

Contreras I, Obreque V, Tesser B, Mora GC.

Biol Res. 1994;27(3-4):233-9.

PMID:
8728836
41.

Clinical isolate of a porinless Salmonella typhi resistant to high levels of chloramphenicol.

Toro CS, Lobos SR, Calderón I, Rodríguez M, Mora GC.

Antimicrob Agents Chemother. 1990 Sep;34(9):1715-9.

42.

Genetic characteristics of the Salmonella typhi strain Ty21a vaccine.

Silva BA, Gonzalez C, Mora GC, Cabello F.

J Infect Dis. 1987 May;155(5):1077-8. No abstract available. Erratum in: J Infect Dis 1987 Aug;156(2):421.

PMID:
3619995
43.

Antibodies to porin antigens of Salmonella typhi induced during typhoid infection in humans.

Calderón I, Lobos SR, Rojas HA, Palomino C, Rodríguez LH, Mora GC.

Infect Immun. 1986 Apr;52(1):209-12.

44.

The hemolytic effect of Salmonella typhi Ty 2 porins.

Calderon I, Lobos SR, Mora GC.

Eur J Biochem. 1984 Jun 15;141(3):579-83.

45.

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