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Astral microtubule forces alter nuclear organization and inhibit DNA repair in budding yeast.

Estrem C, Moore JK.

Mol Biol Cell. 2019 Jul 22;30(16):2000-2013. doi: 10.1091/mbc.E18-12-0808. Epub 2019 May 8.


Convergent estimates of marine nitrogen fixation.

Wang WL, Moore JK, Martiny AC, Primeau FW.

Nature. 2019 Feb;566(7743):205-211. doi: 10.1038/s41586-019-0911-2. Epub 2019 Feb 13.


A unified model for microtubule rescue.

Fees CP, Moore JK.

Mol Biol Cell. 2019 Mar 15;30(6):753-765. doi: 10.1091/mbc.E18-08-0541. Epub 2019 Jan 23.


Gender-affirming hormones and surgery in transgender children and adolescents.

Mahfouda S, Moore JK, Siafarikas A, Hewitt T, Ganti U, Lin A, Zepf FD.

Lancet Diabetes Endocrinol. 2019 Jun;7(6):484-498. doi: 10.1016/S2213-8587(18)30305-X. Epub 2018 Dec 6. Review.


TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity.

Aiken J, Moore JK, Bates EA.

Hum Mol Genet. 2019 Apr 15;28(8):1227-1243. doi: 10.1093/hmg/ddy416.


Using acute tryptophan depletion to investigate predictors of treatment response in adolescents with major depressive disorder: study protocol for a randomised controlled trial.

Stewart RM, Hood SD, Rao P, Moore JK, Runions KC, Murphy SE, Wong JWY, Zepf FD.

Trials. 2018 Aug 10;19(1):434. doi: 10.1186/s13063-018-2791-4.


Aerosol trace metal leaching and impacts on marine microorganisms.

Mahowald NM, Hamilton DS, Mackey KRM, Moore JK, Baker AR, Scanza RA, Zhang Y.

Nat Commun. 2018 Jul 5;9(1):2614. doi: 10.1038/s41467-018-04970-7. Review.


Regulation of microtubule dynamic instability by the carboxy-terminal tail of β-tubulin.

Fees CP, Moore JK.

Life Sci Alliance. 2018 May;1(2). pii: e201800054. doi: 10.26508/lsa.201800054. Epub 2018 Apr 19.


Sustained climate warming drives declining marine biological productivity.

Moore JK, Fu W, Primeau F, Britten GL, Lindsay K, Long M, Doney SC, Mahowald N, Hoffman F, Randerson JT.

Science. 2018 Mar 9;359(6380):1139-1143. doi: 10.1126/science.aao6379.


No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adults.

Hildebrandt CS, Helmbold K, Linden M, Langen KJ, Filss CP, Runions KC, Stewart RM, Rao P, Moore JK, Mahfouda S, Morandini HAE, Wong JWY, Rink L, Zepf FD.

World J Biol Psychiatry. 2019 Jun;20(5):416-423. doi: 10.1080/15622975.2018.1428357. Epub 2018 Apr 26.


Nitrous oxide (N2O) and subsequent open-label SSRI treatment of adolescents with depression (NOTAD): study protocol for a randomised controlled trial.

Stewart RM, Wong JWY, Runions KC, Rao P, Moore JK, Davies SR, von Ungern-Sternberg BS, Sommerfield D, Zepf FD.

Trials. 2017 Dec 22;18(1):617. doi: 10.1186/s13063-017-2342-4.


Functional connectivity of the vigilant-attention network in children and adolescents with attention-deficit/hyperactivity disorder.

Zepf FD, Bubenzer-Busch S, Runions KC, Rao P, Wong JWY, Mahfouda S, Morandini HAE, Stewart RM, Moore JK, Biskup CS, Eickhoff SB, Fink GR, Langner R.

Brain Cogn. 2019 Apr;131:56-65. doi: 10.1016/j.bandc.2017.10.005. Epub 2017 Nov 14.


Quantification of vascular damage in acute kidney injury with fluorine magnetic resonance imaging and spectroscopy.

Moore JK, Chen J, Pan H, Gaut JP, Jain S, Wickline SA.

Magn Reson Med. 2018 Jun;79(6):3144-3153. doi: 10.1002/mrm.26985. Epub 2017 Nov 16.


Differences in serum zinc levels in acutely ill and remitted adolescents and young adults with bulimia nervosa in comparison with healthy controls - a cross-sectional pilot study.

Zepf FD, Rao P, Runions K, Stewart RM, Moore JK, Wong JW, Linden M, Sungurtekin I, Glass F, Gut L, Peetz D, Hintereder G, Schaab M, Poustka F, Wöckel L.

Neuropsychiatr Dis Treat. 2017 Oct 17;13:2621-2630. doi: 10.2147/NDT.S137549. eCollection 2017.


The α-Tubulin gene TUBA1A in Brain Development: A Key Ingredient in the Neuronal Isotype Blend.

Aiken J, Buscaglia G, Bates EA, Moore JK.

J Dev Biol. 2017 Sep;5(3). pii: 8. doi: 10.3390/jdb5030008. Epub 2017 Sep 19.


Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation.

Lee HJ, Jedrychowski MP, Vinayagam A, Wu N, Shyh-Chang N, Hu Y, Min-Wen C, Moore JK, Asara JM, Lyssiotis CA, Perrimon N, Gygi SP, Cantley LC, Kirschner MW.

Cell Rep. 2017 Jul 18;20(3):721-736. doi: 10.1016/j.celrep.2017.06.074.


Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis.

Fraser AR, Pass C, Burgoyne P, Atkinson A, Bailey L, Laurie A, W A McGowan N, Hamid A, Moore JK, Dwyer BJ, Turner ML, Forbes SJ, Campbell JDM.

Cytotherapy. 2017 Sep;19(9):1113-1124. doi: 10.1016/j.jcyt.2017.05.009. Epub 2017 Jun 30.


The Provision of Prescription-Only Medicines for Use on UK-based Overseas Expeditions.

Moore JK, Ladbrook M, Goodyer L, Dallimore J.

Wilderness Environ Med. 2017 Sep;28(3):219-224. doi: 10.1016/j.wem.2017.03.015. Epub 2017 Jun 17.


Dynein is regulated by the stability of its microtubule track.

Estrem C, Fees CP, Moore JK.

J Cell Biol. 2017 Jul 3;216(7):2047-2058. doi: 10.1083/jcb.201611105. Epub 2017 Jun 1.


Puberty suppression in transgender children and adolescents.

Mahfouda S, Moore JK, Siafarikas A, Zepf FD, Lin A.

Lancet Diabetes Endocrinol. 2017 Oct;5(10):816-826. doi: 10.1016/S2213-8587(17)30099-2. Epub 2017 May 22. Review.


Feasibility of Patient Reporting of Symptomatic Adverse Events via the Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) in a Chemoradiotherapy Cooperative Group Multicenter Clinical Trial.

Basch E, Pugh SL, Dueck AC, Mitchell SA, Berk L, Fogh S, Rogak LJ, Gatewood M, Reeve BB, Mendoza TR, O'Mara AM, Denicoff AM, Minasian LM, Bennett AV, Setser A, Schrag D, Roof K, Moore JK, Gergel T, Stephans K, Rimner A, DeNittis A, Bruner DW.

Int J Radiat Oncol Biol Phys. 2017 Jun 1;98(2):409-418. doi: 10.1016/j.ijrobp.2017.02.002. Epub 2017 Feb 10.


High-resolution Imaging and Analysis of Individual Astral Microtubule Dynamics in Budding Yeast.

Fees CP, Estrem C, Moore JK.

J Vis Exp. 2017 Apr 20;(122). doi: 10.3791/55610.


Patients with the worst outcomes after paracetamol (acetaminophen)-induced liver failure have an early monocytopenia.

Moore JK, MacKinnon AC, Man TY, Manning JR, Forbes SJ, Simpson KJ.

Aliment Pharmacol Ther. 2017 Feb;45(3):443-454. doi: 10.1111/apt.13878. Epub 2016 Nov 28.


Bipolar disorder in children and adolescents: diagnostic inpatient rates from 2000 to 2013 in Germany.

Rao P, Moore JK, Stewart R, Runions K, Bear N, Wong JW, Holtmann M, Zepf FD.

Int J Bipolar Disord. 2016 Dec;4(1):23. Epub 2016 Nov 11.


Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells.

Mangan AJ, Sietsema DV, Li D, Moore JK, Citi S, Prekeris R.

Nat Commun. 2016 Aug 3;7:12426. doi: 10.1038/ncomms12426.


Reducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs.

Szkolnicka D, Lucendo-Villarin B, Moore JK, Simpson KJ, Forbes SJ, Hay DC.

Stem Cells Transl Med. 2016 Jun;5(6):764-72. doi: 10.5966/sctm.2015-0117. Epub 2016 Apr 7.


The negatively charged carboxy-terminal tail of β-tubulin promotes proper chromosome segregation.

Fees CP, Aiken J, O'Toole ET, Giddings TH Jr, Moore JK.

Mol Biol Cell. 2016 Jun 1;27(11):1786-96. doi: 10.1091/mbc.E15-05-0300. Epub 2016 Apr 6.


Validation of a robust PCR-based assay for quantifying fragile X CGG repeats.

Kwok YK, Wong KM, Lo FM, Kong GWS, Moore JK, Wu S, Lam STS, Schermer M, Leung TY, Choy KW.

Clin Chim Acta. 2016 May 1;456:137-143. doi: 10.1016/j.cca.2016.02.027. Epub 2016 Mar 3.


Novel α-tubulin mutation disrupts neural development and tubulin proteostasis.

Gartz Hanson M, Aiken J, Sietsema DV, Sept D, Bates EA, Niswander L, Moore JK.

Dev Biol. 2016 Jan 15;409(2):406-19. doi: 10.1016/j.ydbio.2015.11.022. Epub 2015 Nov 30.


In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles.

Lu X, Miousse IR, Pirela SV, Moore JK, Melnyk S, Koturbash I, Demokritou P.

Nanotoxicology. 2016;10(5):629-39. doi: 10.3109/17435390.2015.1108473. Epub 2015 Nov 11.


Diagnostic inexactitude - Reframing and relabelling Disruptive Mood Dysregulation Disorder for ICD-11 does not solve the problem.

Rao P, Moore JK, Stewart R, Hood SD, Runions K, Zepf FD.

Med Hypotheses. 2015 Dec;85(6):1035-6. doi: 10.1016/j.mehy.2015.10.008. Epub 2015 Oct 23. No abstract available.


Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury.

Vliegenthart AD, Shaffer JM, Clarke JI, Peeters LE, Caporali A, Bateman DN, Wood DM, Dargan PI, Craig DG, Moore JK, Thompson AI, Henderson NC, Webb DJ, Sharkey J, Antoine DJ, Park BK, Bailey MA, Lader E, Simpson KJ, Dear JW.

Sci Rep. 2015 Oct 22;5:15501. doi: 10.1038/srep15501.


Characterization of a Mixture of CO2 Adsorption Products in Hyperbranched Aminosilica Adsorbents by (13)C Solid-State NMR.

Moore JK, Sakwa-Novak MA, Chaikittisilp W, Mehta AK, Conradi MS, Jones CW, Hayes SE.

Environ Sci Technol. 2015 Nov 17;49(22):13684-91. doi: 10.1021/acs.est.5b02930. Epub 2015 Oct 29.


A Molecular Rotor Possessing an H-M-H "Spoke" on a P-M-P "Axle": A Platinum(II) trans-Dihydride Spins Rapidly Even at 75 K.

Prack E, O'Keefe CA, Moore JK, Lai A, Lough AJ, Macdonald PM, Conradi MS, Schurko RW, Fekl U.

J Am Chem Soc. 2015 Oct 28;137(42):13464-7. doi: 10.1021/jacs.5b08213. Epub 2015 Oct 14.


Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study.

Moore JK, Mackinnon AC, Wojtacha D, Pope C, Fraser AR, Burgoyne P, Bailey L, Pass C, Atkinson A, Mcgowan NW, Manson L, Turner ML, Campbell JD, Forbes SJ.

Cytotherapy. 2015 Nov;17(11):1604-16. doi: 10.1016/j.jcyt.2015.07.016. Epub 2015 Sep 3.


Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamics.

Nithianantham S, Le S, Seto E, Jia W, Leary J, Corbett KD, Moore JK, Al-Bassam J.

Elife. 2015 Jul 24;4. doi: 10.7554/eLife.08811.


An elaborate data set on human gait and the effect of mechanical perturbations.

Moore JK, Hnat SK, van den Bogert AJ.

PeerJ. 2015 Apr 28;3:e918. doi: 10.7717/peerj.918. eCollection 2015.


An object oriented implementation of the Yeadon human inertia model.

Dembia C, Moore JK, Hubbard M.

Version 2. F1000Res. 2014 Sep 17 [revised 2015 Jan 1];3:223. doi: 10.12688/f1000research.5292.2. eCollection 2014.


Quantitative identification of metastable magnesium carbonate minerals by solid-state 13C NMR spectroscopy.

Moore JK, Surface JA, Brenner A, Wang LS, Skemer P, Conradi MS, Hayes SE.

Environ Sci Technol. 2015 Jan 6;49(1):657-64. doi: 10.1021/es503390d. Epub 2014 Dec 17. Erratum in: Environ Sci Technol. 2015 Feb 3;49(3):1986. Wang, Louis S [added].


Genome-wide analysis reveals novel and discrete functions for tubulin carboxy-terminal tails.

Aiken J, Sept D, Costanzo M, Boone C, Cooper JA, Moore JK.

Curr Biol. 2014 Jun 16;24(12):1295-1303. doi: 10.1016/j.cub.2014.03.078. Epub 2014 May 15.


Glycosylated yellow laccases of the basidiomycete Stropharia aeruginosa.

Daroch M, Houghton CA, Moore JK, Wilkinson MC, Carnell AJ, Bates AD, Iwanejko LA.

Enzyme Microb Technol. 2014 May 10;58-59:1-7. doi: 10.1016/j.enzmictec.2014.02.003. Epub 2014 Feb 14.


Systematic review: the effects of autologous stem cell therapy for patients with liver disease.

Moore JK, Stutchfield BM, Forbes SJ.

Aliment Pharmacol Ther. 2014 Apr;39(7):673-85. doi: 10.1111/apt.12645. Epub 2014 Feb 13. Review.


Acute kidney injury in acute liver failure: a review.

Moore JK, Love E, Craig DG, Hayes PC, Simpson KJ.

Expert Rev Gastroenterol Hepatol. 2013 Nov;7(8):701-12. doi: 10.1586/17474124.2013.837264. Epub 2013 Oct 17. Review.


Features of free software packages in flow cytometry: a comparison between four non-commercial software sources.

Sahraneshin Samani F, Moore JK, Khosravani P, Ebrahimi M.

Cytotechnology. 2014 Aug;66(4):555-9. doi: 10.1007/s10616-013-9609-8. Epub 2013 Jul 10.


Geminin deploys multiple mechanisms to regulate Cdt1 before cell division thus ensuring the proper execution of DNA replication.

Ballabeni A, Zamponi R, Moore JK, Helin K, Kirschner MW.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2848-53. doi: 10.1073/pnas.1310677110. Epub 2013 Jul 8.


Persistently elevated troponin I in paracetamol hepatotoxicity: association with liver injury, organ failure, and outcome.

Moore JK, Craig DG, Pryde EA, Walker SW, Beckett GJ, Hayes PC, Simpson KJ.

Clin Toxicol (Phila). 2013 Aug;51(7):532-9. doi: 10.3109/15563650.2013.816853. Epub 2013 Jul 5.


Stopped in its tracks: negative regulation of the dynein motor by the yeast protein She1.

Moore JK.

Bioessays. 2013 Aug;35(8):677-82. doi: 10.1002/bies.201300016. Epub 2013 May 13.


Dynein and dynactin leverage their bivalent character to form a high-affinity interaction.

Siglin AE, Sun S, Moore JK, Tan S, Poenie M, Lear JD, Polenova T, Cooper JA, Williams JC.

PLoS One. 2013;8(4):e59453. doi: 10.1371/journal.pone.0059453. Epub 2013 Apr 5.


Psychotropic drug prescribing in an Australian specialist child and adolescent eating disorder service: a retrospective study.

Moore JK, Watson HJ, Harper E, McCormack J, Nguyen T.

J Eat Disord. 2013 Aug 8;1:27. doi: 10.1186/2050-2974-1-27. eCollection 2013.


Severe hyperhomocysteinemia promotes bone marrow-derived and resident inflammatory monocyte differentiation and atherosclerosis in LDLr/CBS-deficient mice.

Zhang D, Fang P, Jiang X, Nelson J, Moore JK, Kruger WD, Berretta RM, Houser SR, Yang X, Wang H.

Circ Res. 2012 Jun 22;111(1):37-49. doi: 10.1161/CIRCRESAHA.112.269472. Epub 2012 May 24.

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