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Items: 1 to 50 of 190

1.

1,3-Dinitrobenze-Induced Genotoxicity Through Altering Nuclear Integrity of Diploid and Polyploidy Germ Cells.

Peiris LDC, Chathu P, Perera DDBD, Moore HD.

Dose Response. 2019 Sep 22;17(3):1559325819876760. doi: 10.1177/1559325819876760. eCollection 2019 Jul-Sep.

2.

Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform.

Stacey GN, Andrews PW, Barbaric I, Boiers C, Chandra A, Cossu G, Csontos L, Frith TJ, Halliwell JA, Hewitt Z, McCall M, Moore HD, Parmar M, Panico MB, Pisupati V, Shichkin VP, Stacey AR, Tedesco FS, Thompson O, Wagey R.

Regen Med. 2019 Mar;14(3):243-255. doi: 10.2217/rme-2019-0001. Epub 2019 Apr 2.

3.

Targeted mass spectrometry enables robust quantification of FANCD2 mono-ubiquitination in response to DNA damage.

Whiteaker JR, Zhao L, Ivey RG, Sanchez-Bonilla M, Moore HD, Schoenherr RM, Yan P, Lin C, Shimamura A, Paulovich AG.

DNA Repair (Amst). 2018 May;65:47-53. doi: 10.1016/j.dnarep.2018.03.003. Epub 2018 Mar 21.

4.

A Multiplexed Mass Spectrometry-Based Assay for Robust Quantification of Phosphosignaling in Response to DNA Damage.

Whiteaker JR, Zhao L, Saul R, Kaczmarczyk JA, Schoenherr RM, Moore HD, Jones-Weinert C, Ivey RG, Lin C, Hiltke T, Reding KW, Whiteley G, Wang P, Paulovich AG.

Radiat Res. 2018 May;189(5):505-518. doi: 10.1667/RR14963.1. Epub 2018 Feb 23.

5.

Detecting Genetic Mosaicism in Cultures of Human Pluripotent Stem Cells.

Baker D, Hirst AJ, Gokhale PJ, Juarez MA, Williams S, Wheeler M, Bean K, Allison TF, Moore HD, Andrews PW, Barbaric I.

Stem Cell Reports. 2016 Nov 8;7(5):998-1012. doi: 10.1016/j.stemcr.2016.10.003.

6.

Pluripotency and differentiation of cells from human testicular sperm extraction: An investigation of cell stemness.

Sadeghian-Nodoushan F, Aflatoonian R, Borzouie Z, Akyash F, Fesahat F, Soleimani M, Aghajanpour S, Moore HD, Aflatoonian B.

Mol Reprod Dev. 2016 Apr;83(4):312-23. doi: 10.1002/mrd.22620. Epub 2016 Feb 22.

PMID:
27077675
7.

Immobilized Metal Affinity Chromatography Coupled to Multiple Reaction Monitoring Enables Reproducible Quantification of Phospho-signaling.

Kennedy JJ, Yan P, Zhao L, Ivey RG, Voytovich UJ, Moore HD, Lin C, Pogosova-Agadjanyan EL, Stirewalt DL, Reding KW, Whiteaker JR, Paulovich AG.

Mol Cell Proteomics. 2016 Feb;15(2):726-39. doi: 10.1074/mcp.O115.054940. Epub 2015 Nov 30.

8.

The Molecular Karyotype of 25 Clinical-Grade Human Embryonic Stem Cell Lines.

Canham MA, Van Deusen A, Brison DR, De Sousa PA, Downie J, Devito L, Hewitt ZA, Ilic D, Kimber SJ, Moore HD, Murray H, Kunath T.

Sci Rep. 2015 Nov 26;5:17258. doi: 10.1038/srep17258.

9.

Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry Enables Multiplex, Quantitative Pharmacodynamic Studies of Phospho-Signaling.

Whiteaker JR, Zhao L, Yan P, Ivey RG, Voytovich UJ, Moore HD, Lin C, Paulovich AG.

Mol Cell Proteomics. 2015 Aug;14(8):2261-73. doi: 10.1074/mcp.O115.050351. Epub 2015 May 18.

10.

CD133-enriched Xeno-Free human embryonic-derived neural stem cells expand rapidly in culture and do not form teratomas in immunodeficient mice.

Haus DL, Nguyen HX, Gold EM, Kamei N, Perez H, Moore HD, Anderson AJ, Cummings BJ.

Stem Cell Res. 2014 Sep;13(2):214-26. doi: 10.1016/j.scr.2014.06.008. Epub 2014 Jul 10.

11.

Modifiable and non-modifiable risk factors for poor sperm morphology.

Pacey AA, Povey AC, Clyma JA, McNamee R, Moore HD, Baillie H, Cherry NM; Participating Centres of Chaps-UK.

Hum Reprod. 2014 Aug;29(8):1629-36. doi: 10.1093/humrep/deu116. Epub 2014 Jun 4.

PMID:
24899128
12.

The human salivary proteome is radiation responsive.

Moore HD, Ivey RG, Voytovich UJ, Lin C, Stirewalt DL, Pogosova-Agadjanyan EL, Paulovich AG.

Radiat Res. 2014 May;181(5):521-30. doi: 10.1667/RR13586.1. Epub 2014 Apr 10.

13.

Will it be possible to restore sperm production after childhood cancer treatment?

Pacey AA, Moore HD.

Regen Med. 2013 Sep;8(5):523-5. doi: 10.2217/rme.13.57. No abstract available.

PMID:
23998745
14.

Sperm speed is associated with sex bias of siblings in a human population.

Mossman JA, Slate J, Birkhead TR, Moore HD, Pacey AA.

Asian J Androl. 2013 Jan;15(1):152-4. doi: 10.1038/aja.2012.109. Epub 2012 Dec 3.

15.

Transforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells.

Alagaratnam S, Harrison N, Bakken AC, Hoff AM, Jones M, Sveen A, Moore HD, Andrews PW, Lothe RA, Skotheim RI.

Stem Cells Dev. 2013 Apr 1;22(7):1136-46. doi: 10.1089/scd.2012.0369. Epub 2013 Jan 4.

PMID:
23137282
16.

Variation in mean human sperm length is linked with semen characteristics.

Mossman JA, Pearson JT, Moore HD, Pacey AA.

Hum Reprod. 2013 Jan;28(1):22-32. doi: 10.1093/humrep/des382. Epub 2012 Oct 28.

PMID:
23108349
17.

Restoration of auditory evoked responses by human ES-cell-derived otic progenitors.

Chen W, Jongkamonwiwat N, Abbas L, Eshtan SJ, Johnson SL, Kuhn S, Milo M, Thurlow JK, Andrews PW, Marcotti W, Moore HD, Rivolta MN.

Nature. 2012 Oct 11;490(7419):278-82. doi: 10.1038/nature11415. Epub 2012 Sep 12.

18.

Modifiable and non-modifiable risk factors for poor semen quality: a case-referent study.

Povey AC, Clyma JA, McNamee R, Moore HD, Baillie H, Pacey AA, Cherry NM; Participating Centres of Chaps-uk.

Hum Reprod. 2012 Sep;27(9):2799-806. doi: 10.1093/humrep/des183. Epub 2012 Jun 12.

PMID:
22695289
19.

A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice.

Mohanty ST, Cairney CJ, Chantry AD, Madan S, Fernandes JA, Howe SJ, Moore HD, Thompson MJ, Chen B, Thrasher A, Keith WN, Bellantuono I.

Stem Cells. 2012 Jun;30(6):1134-43. doi: 10.1002/stem.1065.

20.

Mitochondrial haplotype does not influence sperm motility in a UK population of men.

Mossman JA, Slate J, Birkhead TR, Moore HD, Pacey AA.

Hum Reprod. 2012 Mar;27(3):641-51. doi: 10.1093/humrep/der438. Epub 2012 Jan 2.

PMID:
22215629
21.

Pinacidil enhances survival of cryopreserved human embryonic stem cells.

Barbaric I, Jones M, Buchner K, Baker D, Andrews PW, Moore HD.

Cryobiology. 2011 Dec;63(3):298-305. doi: 10.1016/j.cryobiol.2011.10.002. Epub 2011 Oct 17.

PMID:
22027383
22.

The morphology of the squirrel spermatozoon: a highly complex male gamete with a massive acrosome.

Breed WG, Tan S, Leigh CM, Aplin KP, Dvorakova-Hortova K, Moore HD.

J Morphol. 2011 Jul;272(7):883-9. doi: 10.1002/jmor.10955. Epub 2011 May 5.

PMID:
21547937
23.

Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISA.

Ivey RG, Moore HD, Voytovich UJ, Thienes CP, Lorentzen TD, Pogosova-Agadjanyan EL, Frayo S, Izaguirre VK, Lundberg SJ, Hedin L, Badiozamani KR, Hoofnagle AN, Stirewalt DL, Wang P, Georges GE, Gopal AK, Paulovich AG.

Radiat Res. 2011 Mar;175(3):266-81. doi: 10.1667/RR2402.1. Epub 2010 Dec 20.

24.

Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach.

Plews JR, Li J, Jones M, Moore HD, Mason C, Andrews PW, Na J.

PLoS One. 2010 Dec 30;5(12):e14397. doi: 10.1371/journal.pone.0014397.

25.

Characterization of invasive trophoblasts generated from human embryonic stem cells.

Udayashankar R, Baker D, Tuckerman E, Laird S, Li TC, Moore HD.

Hum Reprod. 2011 Feb;26(2):398-406. doi: 10.1093/humrep/deq350. Epub 2010 Dec 16.

PMID:
21163855
26.

A novel method for prevention of intraoperative fracture in cementless hip arthroplasty: vibration analysis during femoral component insertion.

Meneghini RM, Guthrie M, Moore HD, Abou-Trabi D, Cornwell P, Rosenberg AG.

Surg Technol Int. 2010 Oct;20:334-9.

PMID:
21082583
27.

The effects of culture on genomic imprinting profiles in human embryonic and fetal mesenchymal stem cells.

Frost J, Monk D, Moschidou D, Guillot PV, Stanier P, Minger SL, Fisk NM, Moore HD, Moore GE.

Epigenetics. 2011 Jan;6(1):52-62. doi: 10.4161/epi.6.1.13361. Epub 2011 Jan 1.

28.

Telomeric NAP1L4 and OSBPL5 of the KCNQ1 cluster, and the DECORIN gene are not imprinted in human trophoblast stem cells.

Frost JM, Udayashankar R, Moore HD, Moore GE.

PLoS One. 2010 Jul 14;5(7):e11595. doi: 10.1371/journal.pone.0011595.

29.

High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity.

Närvä E, Autio R, Rahkonen N, Kong L, Harrison N, Kitsberg D, Borghese L, Itskovitz-Eldor J, Rasool O, Dvorak P, Hovatta O, Otonkoski T, Tuuri T, Cui W, Brüstle O, Baker D, Maltby E, Moore HD, Benvenisty N, Andrews PW, Yli-Harja O, Lahesmaa R.

Nat Biotechnol. 2010 Apr;28(4):371-7. doi: 10.1038/nbt.1615. Epub 2010 Mar 28.

PMID:
20351689
30.

In situ cryopreservation of human embryonic stem cells in gas-permeable membrane culture cassettes for high post-thaw yield and good manufacturing practice.

Amps KJ, Jones M, Baker D, Moore HD.

Cryobiology. 2010 Jun;60(3):344-50. doi: 10.1016/j.cryobiol.2010.03.007. Epub 2010 Mar 27.

PMID:
20347760
31.

In vitro post-meiotic germ cell development from human embryonic stem cells.

Aflatoonian B, Ruban L, Jones M, Aflatoonian R, Fazeli A, Moore HD.

Hum Reprod. 2009 Dec;24(12):3150-9. doi: 10.1093/humrep/dep334. Epub 2009 Sep 20.

PMID:
19770126
32.

Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte.

Sonne SB, Almstrup K, Dalgaard M, Juncker AS, Edsgard D, Ruban L, Harrison NJ, Schwager C, Abdollahi A, Huber PE, Brunak S, Gjerdrum LM, Moore HD, Andrews PW, Skakkebaek NE, Rajpert-De Meyts E, Leffers H.

Cancer Res. 2009 Jun 15;69(12):5241-50. doi: 10.1158/0008-5472.CAN-08-4554. Epub 2009 Jun 2.

33.

Generation of T cells from human embryonic stem cell-derived hematopoietic zones.

Timmermans F, Velghe I, Vanwalleghem L, De Smedt M, Van Coppernolle S, Taghon T, Moore HD, Leclercq G, Langerak AW, Kerre T, Plum J, Vandekerckhove B.

J Immunol. 2009 Jun 1;182(11):6879-88. doi: 10.4049/jimmunol.0803670.

34.

Human fetal auditory stem cells can be expanded in vitro and differentiate into functional auditory neurons and hair cell-like cells.

Chen W, Johnson SL, Marcotti W, Andrews PW, Moore HD, Rivolta MN.

Stem Cells. 2009 May;27(5):1196-204. doi: 10.1002/stem.62.

35.

Specific knockdown of OCT4 in human embryonic stem cells by inducible short hairpin RNA interference.

Zafarana G, Avery SR, Avery K, Moore HD, Andrews PW.

Stem Cells. 2009 Apr;27(4):776-82. doi: 10.1002/stem.5.

36.

Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay.

Carr AJ, Vugler A, Lawrence J, Chen LL, Ahmado A, Chen FK, Semo M, Gias C, da Cruz L, Moore HD, Walsh J, Coffey PJ.

Mol Vis. 2009;15:283-95. Epub 2009 Feb 6.

37.

Cancer genes hypermethylated in human embryonic stem cells.

Calvanese V, Horrillo A, Hmadcha A, Suarez-Alvarez B, Fernandez AF, Lara E, Casado S, Menendez P, Bueno C, Garcia-Castro J, Rubio R, Lapunzina P, Alaminos M, Borghese L, Terstegge S, Harrison NJ, Moore HD, Brüstle O, Lopez-Larrea C, Andrews PW, Soria B, Esteller M, Fraga MF.

PLoS One. 2008 Sep 29;3(9):e3294. doi: 10.1371/journal.pone.0003294.

38.

Heparin promotes the growth of human embryonic stem cells in a defined serum-free medium.

Furue MK, Na J, Jackson JP, Okamoto T, Jones M, Baker D, Hata R, Moore HD, Sato JD, Andrews PW.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13409-14. doi: 10.1073/pnas.0806136105. Epub 2008 Aug 25. Erratum in: Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):18071.

39.

PAX4 enhances beta-cell differentiation of human embryonic stem cells.

Liew CG, Shah NN, Briston SJ, Shepherd RM, Khoo CP, Dunne MJ, Moore HD, Cosgrove KE, Andrews PW.

PLoS One. 2008 Mar 12;3(3):e1783. doi: 10.1371/journal.pone.0001783.

40.

Embryonic stem cells and prospects for their use in regenerative medicine approaches to motor neurone disease.

Christou YA, Moore HD, Shaw PJ, Monk PN.

Neuropathol Appl Neurobiol. 2007 Oct;33(5):485-98. Review.

PMID:
17854436
41.

Derivation of GMP raw materials for use in regenerative medicine: hESC-based therapies, progress toward clinical application.

Hewitt ZA, Amps KJ, Moore HD.

Clin Pharmacol Ther. 2007 Oct;82(4):448-52. Epub 2007 Aug 8. Review.

PMID:
17687270
42.

The human fetal cochlea can be a source for auditory progenitors/stem cells isolation.

Chen W, Cacciabue-Rivolta DI, Moore HD, Rivolta MN.

Hear Res. 2007 Nov;233(1-2):23-9. Epub 2007 Jun 20.

PMID:
17646067
43.

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.

International Stem Cell Initiative, Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, Andrews PW, Beighton G, Bello PA, Benvenisty N, Berry LS, Bevan S, Blum B, Brooking J, Chen KG, Choo AB, Churchill GA, Corbel M, Damjanov I, Draper JS, Dvorak P, Emanuelsson K, Fleck RA, Ford A, Gertow K, Gertsenstein M, Gokhale PJ, Hamilton RS, Hampl A, Healy LE, Hovatta O, Hyllner J, Imreh MP, Itskovitz-Eldor J, Jackson J, Johnson JL, Jones M, Kee K, King BL, Knowles BB, Lako M, Lebrin F, Mallon BS, Manning D, Mayshar Y, McKay RD, Michalska AE, Mikkola M, Mileikovsky M, Minger SL, Moore HD, Mummery CL, Nagy A, Nakatsuji N, O'Brien CM, Oh SK, Olsson C, Otonkoski T, Park KY, Passier R, Patel H, Patel M, Pedersen R, Pera MF, Piekarczyk MS, Pera RA, Reubinoff BE, Robins AJ, Rossant J, Rugg-Gunn P, Schulz TC, Semb H, Sherrer ES, Siemen H, Stacey GN, Stojkovic M, Suemori H, Szatkiewicz J, Turetsky T, Tuuri T, van den Brink S, Vintersten K, Vuoristo S, Ward D, Weaver TA, Young LA, Zhang W.

Nat Biotechnol. 2007 Jul;25(7):803-16. Epub 2007 Jun 17.

PMID:
17572666
44.

CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells.

Schneider MA, Meingassner JG, Lipp M, Moore HD, Rot A.

J Exp Med. 2007 Apr 16;204(4):735-45. Epub 2007 Mar 19.

45.

Adaptation to culture of human embryonic stem cells and oncogenesis in vivo.

Baker DE, Harrison NJ, Maltby E, Smith K, Moore HD, Shaw PJ, Heath PR, Holden H, Andrews PW.

Nat Biotechnol. 2007 Feb;25(2):207-15.

PMID:
17287758
46.

By hook or by crook? Morphometry, competition and cooperation in rodent sperm.

Immler S, Moore HD, Breed WG, Birkhead TR.

PLoS One. 2007 Jan 24;2(1):e170.

47.

Cytotrophoblast stem cell lines derived from human embryonic stem cells and their capacity to mimic invasive implantation events.

Harun R, Ruban L, Matin M, Draper J, Jenkins NM, Liew GC, Andrews PW, Li TC, Laird SM, Moore HD.

Hum Reprod. 2006 Jun;21(6):1349-58. Epub 2006 Feb 14.

48.

Dysfunction of the mitotic:meiotic switch as a potential cause of neoplastic conversion of primordial germ cells.

Adamah DJ, Gokhale PJ, Eastwood DJ, Rajpert De-Meyts E, Goepel J, Walsh JR, Moore HD, Andrews PW.

Int J Androl. 2006 Feb;29(1):219-27.

PMID:
16466543
49.

Molecular mechanisms during sperm capacitation.

Brewis IA, Moore HD, Fraser LR, Holt WV, Baldi E, Luconi M, Gadella BM, Ford WC, Harrison RA.

Hum Fertil (Camb). 2005 Dec;8(4):253-61. Review. No abstract available.

PMID:
16393825
50.

Gametes alter the oviductal secretory proteome.

Georgiou AS, Sostaric E, Wong CH, Snijders AP, Wright PC, Moore HD, Fazeli A.

Mol Cell Proteomics. 2005 Nov;4(11):1785-96. Epub 2005 Aug 16.

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