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Items: 1 to 50 of 311

1.

Expression of CD1d by astrocytes corresponds with relative activity in multiple sclerosis lesions.

Muir FGW, Samadi-Bahrami Z, Moore GRW, Quandt JA.

Brain Pathol. 2019 May 3. doi: 10.1111/bpa.12733. [Epub ahead of print]

PMID:
31050367
2.

Reaction of O2 with a diiron protein generates a mixed-valent Fe2+/Fe3+ center and peroxide.

Bradley JM, Svistunenko DA, Pullin J, Hill N, Stuart RK, Palenik B, Wilson MT, Hemmings AM, Moore GR, Le Brun NE.

Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):2058-2067. doi: 10.1073/pnas.1809913116. Epub 2019 Jan 18.

PMID:
30659147
3.

Coexistence of Multiple Sclerosis and Alzheimer's disease: A review.

Luczynski P, Laule C, Hsiung GR, Moore GRW, Tremlett H.

Mult Scler Relat Disord. 2019 Jan;27:232-238. doi: 10.1016/j.msard.2018.10.109. Epub 2018 Oct 27. Review.

PMID:
30415025
4.

Diffusely Abnormal White Matter, T2 Burden of Disease, and Brain Volume in Relapsing-Remitting Multiple Sclerosis.

Vertinsky AT, Li DKB, Vavasour IM, Miropolsky V, Zhao G, Zhao Y, Riddehough A, Moore GRW, Traboulsee A, Laule C.

J Neuroimaging. 2019 Jan;29(1):151-159. doi: 10.1111/jon.12574. Epub 2018 Oct 30.

PMID:
30376195
5.

Myelin water imaging to detect demyelination and remyelination and its validation in pathology.

Laule C, Moore GRW.

Brain Pathol. 2018 Sep;28(5):750-764. doi: 10.1111/bpa.12645. Review.

PMID:
30375119
6.

Correlating new directional measures of myelin and axonal integrity in T2-weighted MRI with quantitative histology in multiple sclerosis.

Sharma S, Laule C, Moore GRW, Li DKB, Zhang Y.

J Neurosci Methods. 2019 Jan 1;311:369-376. doi: 10.1016/j.jneumeth.2018.09.020. Epub 2018 Sep 19.

PMID:
30240805
7.

Naturally Occurring Disease-Related Mutations in the 40-57 Ω-Loop of Human Cytochrome c Control Triggering of the Alkaline Isomerization.

Deacon OM, Svistunenko DA, Moore GR, Wilson MT, Worrall JAR.

Biochemistry. 2018 Jul 24;57(29):4276-4288. doi: 10.1021/acs.biochem.8b00520. Epub 2018 Jul 11.

PMID:
29949346
8.

The N-terminal domains of Bacillus subtilis CopA do not form a stable complex in the absence of their inter-domain linker.

Zhou L, Kay KL, Hecht O, Moore GR, Le Brun NE.

Biochim Biophys Acta Proteins Proteom. 2018 Feb;1866(2):275-282. doi: 10.1016/j.bbapap.2017.11.008. Epub 2017 Nov 14.

PMID:
29146226
9.

Heightened Dynamics of the Oxidized Y48H Variant of Human Cytochrome c Increases Its Peroxidatic Activity.

Deacon OM, Karsisiotis AI, Moreno-Chicano T, Hough MA, Macdonald C, Blumenschein TMA, Wilson MT, Moore GR, Worrall JAR.

Biochemistry. 2017 Nov 21;56(46):6111-6124. doi: 10.1021/acs.biochem.7b00890. Epub 2017 Nov 8.

PMID:
29083920
10.

The Two-State Prehensile Tail of the Antibacterial Toxin Colicin N.

Johnson CL, Solovyova AS, Hecht O, Macdonald C, Waller H, Grossmann JG, Moore GR, Lakey JH.

Biophys J. 2017 Oct 17;113(8):1673-1684. doi: 10.1016/j.bpj.2017.08.030.

11.

Tyr25, Tyr58 and Trp133 of Escherichia coli bacterioferritin transfer electrons between iron in the central cavity and the ferroxidase centre.

Bradley JM, Svistunenko DA, Moore GR, Le Brun NE.

Metallomics. 2017 Oct 18;9(10):1421-1428. doi: 10.1039/c7mt00187h.

PMID:
28914315
12.

Global loss of myelin water over 5 years in multiple sclerosis normal-appearing white matter.

Vavasour IM, Huijskens SC, Li DK, Traboulsee AL, Mädler B, Kolind SH, Rauscher A, Moore GW, MacKay AL, Laule C.

Mult Scler. 2018 Oct;24(12):1557-1568. doi: 10.1177/1352458517723717. Epub 2017 Aug 7.

PMID:
28782447
13.

Myelin regulatory factor drives remyelination in multiple sclerosis.

Duncan GJ, Plemel JR, Assinck P, Manesh SB, Muir FGW, Hirata R, Berson M, Liu J, Wegner M, Emery B, Moore GRW, Tetzlaff W.

Acta Neuropathol. 2017 Sep;134(3):403-422. doi: 10.1007/s00401-017-1741-7. Epub 2017 Jun 19.

PMID:
28631093
14.

Diversity of Fe2+ entry and oxidation in ferritins.

Bradley JM, Moore GR, Le Brun NE.

Curr Opin Chem Biol. 2017 Apr;37:122-128. doi: 10.1016/j.cbpa.2017.02.027. Epub 2017 Mar 15. Review.

PMID:
28314217
15.

Near-complete backbone resonance assignments of acid-denatured human cytochrome c in dimethylsulfoxide: a prelude to studying interactions with phospholipids.

Karsisiotis AI, Deacon OM, Macdonald C, Blumenschein TMA, Moore GR, Worrall JAR.

Biomol NMR Assign. 2017 Oct;11(2):165-168. doi: 10.1007/s12104-017-9740-0. Epub 2017 Mar 4.

PMID:
28260216
16.

An Unusual Case of Rabies Encephalitis.

Walker G, Thiessen B, Graeb D, Moore GR, Mackenzie IR.

Can J Neurol Sci. 2016 Nov;43(6):852-855. Epub 2016 Aug 31.

PMID:
27579969
17.

Three Aromatic Residues are Required for Electron Transfer during Iron Mineralization in Bacterioferritin.

Bradley JM, Svistunenko DA, Lawson TL, Hemmings AM, Moore GR, Le Brun NE.

Angew Chem Weinheim Bergstr Ger. 2015 Dec 1;127(49):14976-14980. Epub 2015 Oct 16.

18.

Increased dynamics in the 40-57 Ω-loop of the G41S variant of human cytochrome c promote its pro-apoptotic conformation.

Karsisiotis AI, Deacon OM, Wilson MT, Macdonald C, Blumenschein TM, Moore GR, Worrall JA.

Sci Rep. 2016 Jul 27;6:30447. doi: 10.1038/srep30447.

19.

Ionotropic glutamate receptor expression in human white matter.

Christensen PC, Samadi-Bahrami Z, Pavlov V, Stys PK, Moore GRW.

Neurosci Lett. 2016 Sep 6;630:1-8. doi: 10.1016/j.neulet.2016.07.030. Epub 2016 Jul 18.

PMID:
27443784
20.

Complement and Humoral Adaptive Immunity in the Human Choroid Plexus: Roles for Stromal Concretions, Basement Membranes, and Epithelium.

Moore GR, Laule C, Leung E, Pavlova V, Morgan BP, Esiri MM.

J Neuropathol Exp Neurol. 2016 May;75(5):415-28. doi: 10.1093/jnen/nlw017. Epub 2016 Mar 19.

21.

Ferritins: furnishing proteins with iron.

Bradley JM, Le Brun NE, Moore GR.

J Biol Inorg Chem. 2016 Mar;21(1):13-28. doi: 10.1007/s00775-016-1336-0. Epub 2016 Jan 29. Review.

22.

High-resolution myelin water imaging in post-mortem multiple sclerosis spinal cord: A case report.

Laule C, Yung A, Pavolva V, Bohnet B, Kozlowski P, Hashimoto SA, Yip S, Li DK, Moore GW.

Mult Scler. 2016 Oct;22(11):1485-1489. Epub 2016 Jan 27.

PMID:
26819263
23.

Three Aromatic Residues are Required for Electron Transfer during Iron Mineralization in Bacterioferritin.

Bradley JM, Svistunenko DA, Lawson TL, Hemmings AM, Moore GR, Le Brun NE.

Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14763-7. doi: 10.1002/anie.201507486. Epub 2015 Oct 16.

24.

A Diatom Ferritin Optimized for Iron Oxidation but Not Iron Storage.

Pfaffen S, Bradley JM, Abdulqadir R, Firme MR, Moore GR, Le Brun NE, Murphy ME.

J Biol Chem. 2015 Nov 20;290(47):28416-27. doi: 10.1074/jbc.M115.669713. Epub 2015 Sep 22.

25.

Amyotrophic lateral sclerosis presentation of a human T-lymphotropic virus type-1 myelopathy--insight into pathogenesis.

Alkhawajah NM, Chapman KM, Moore GR, Oger J.

APMIS. 2015 Sep;123(9):815-20. doi: 10.1111/apm.12422. Epub 2015 Jul 30.

PMID:
26224593
26.

Backbone resonance assignments of ferric human cytochrome c and the pro-apoptotic G41S mutant in the ferric and ferrous states.

Karsisiotis AI, Deacon OM, Rajagopal BS, Macdonald C, Blumenschein TM, Moore GR, Worrall JA.

Biomol NMR Assign. 2015 Oct;9(2):415-9. doi: 10.1007/s12104-015-9621-3. Epub 2015 Jun 30.

PMID:
26123826
27.

The B-type channel is a major route for iron entry into the ferroxidase center and central cavity of bacterioferritin.

Wong SG, Grigg JC, Le Brun NE, Moore GR, Murphy ME, Mauk AG.

J Biol Chem. 2015 Feb 6;290(6):3732-9. doi: 10.1074/jbc.M114.623082. Epub 2014 Dec 15.

28.

Mechanisms of iron mineralization in ferritins: one size does not fit all.

Bradley JM, Moore GR, Le Brun NE.

J Biol Inorg Chem. 2014 Aug;19(6):775-85. doi: 10.1007/s00775-014-1136-3. Epub 2014 Apr 19. Review.

PMID:
24748222
29.

Protein destabilisation in ionic liquids: the role of preferential interactions in denaturation.

Figueiredo AM, Sardinha J, Moore GR, Cabrita EJ.

Phys Chem Chem Phys. 2013 Dec 7;15(45):19632-43. doi: 10.1039/c3cp53395f. Epub 2013 Oct 17.

PMID:
24132185
30.

Conformational dynamics is more important than helical propensity for the folding of the all α-helical protein Im7.

Figueiredo AM, Whittaker SB, Knowling SE, Radford SE, Moore GR.

Protein Sci. 2013 Dec;22(12):1722-38. doi: 10.1002/pro.2372. Epub 2013 Oct 19.

31.

Pathological correlates of magnetic resonance imaging texture heterogeneity in multiple sclerosis.

Zhang Y, Moore GR, Laule C, Bjarnason TA, Kozlowski P, Traboulsee A, Li DK.

Ann Neurol. 2013 Jul;74(1):91-9. doi: 10.1002/ana.23867. Epub 2013 Aug 12.

PMID:
23939554
32.

Magnetic resonance frequency shifts during acute MS lesion formation.

Wiggermann V, Hernández Torres E, Vavasour IM, Moore GR, Laule C, MacKay AL, Li DK, Traboulsee A, Rauscher A.

Neurology. 2013 Jul 16;81(3):211-8. doi: 10.1212/WNL.0b013e31829bfd63. Epub 2013 Jun 12.

33.

Diffusely abnormal white matter in multiple sclerosis: further histologic studies provide evidence for a primary lipid abnormality with neurodegeneration.

Laule C, Pavlova V, Leung E, Zhao G, MacKay AL, Kozlowski P, Traboulsee AL, Li DK, Moore GR.

J Neuropathol Exp Neurol. 2013 Jan;72(1):42-52. doi: 10.1097/NEN.0b013e31827bced3.

PMID:
23242281
34.

Intrinsically disordered proteins: lessons from colicins.

Hecht O, Macdonald C, Moore GR.

Biochem Soc Trans. 2012 Dec 1;40(6):1534-8. doi: 10.1042/BST20120198. Review.

PMID:
23176512
35.

Orbicularis oculi muscle biopsies for mitochondrial DNA analysis in suspected mitochondrial myopathy.

Roefs AM, Waters PJ, Moore GR, Dolman PJ.

Br J Ophthalmol. 2012 Oct;96(10):1296-9. Epub 2012 Aug 14.

PMID:
22893396
36.

Neuropathologic correlates of magnetic resonance imaging in multiple sclerosis.

Moore GR, Laule C.

J Neuropathol Exp Neurol. 2012 Sep;71(9):762-78. doi: 10.1097/NEN.0b013e3182676388. Review.

PMID:
22892523
37.

Structural evidence that colicin A protein binds to a novel binding site of TolA protein in Escherichia coli periplasm.

Li C, Zhang Y, Vankemmelbeke M, Hecht O, Aleanizy FS, Macdonald C, Moore GR, James R, Penfold CN.

J Biol Chem. 2012 Jun 1;287(23):19048-57. doi: 10.1074/jbc.M112.342246. Epub 2012 Apr 9.

38.

Fe-haem bound to Escherichia coli bacterioferritin accelerates iron core formation by an electron transfer mechanism.

Wong SG, Abdulqadir R, Le Brun NE, Moore GR, Mauk AG.

Biochem J. 2012 Jun 15;444(3):553-60. doi: 10.1042/BJ20112200.

PMID:
22458666
39.

Understanding how small helical proteins fold: conformational dynamics of Im proteins relevant to their folding landscapes.

Figueiredo AM, Moore GR, Whittaker SB.

Biochem Soc Trans. 2012 Apr;40(2):424-8. doi: 10.1042/BST20110739. Review.

PMID:
22435824
40.

Cu(I)- and proton-binding properties of the first N-terminal soluble domain of Bacillus subtilis CopA.

Zhou L, Singleton C, Hecht O, Moore GR, Le Brun NE.

FEBS J. 2012 Jan;279(2):285-98. doi: 10.1111/j.1742-4658.2011.08422.x. Epub 2011 Dec 6.

41.

NMR characterisation of the relationship between frustration and the excited state of Im7.

Whittaker SB, Clayden NJ, Moore GR.

J Mol Biol. 2011 Dec 9;414(4):511-29. doi: 10.1016/j.jmb.2011.09.038. Epub 2011 Oct 14.

PMID:
22019474
42.

Uptake of free HPV vaccination among young women: a comparison of rural versus urban rates.

Crosby RA, Casey BR, Vanderpool R, Collins T, Moore GR.

J Rural Health. 2011 Winter;27(4):380-4. doi: 10.1111/j.1748-0361.2010.00354.x. Epub 2011 Jan 4.

43.

Current concepts in the neuropathology and pathogenesis of multiple sclerosis.

Moore GR.

Can J Neurol Sci. 2010 Sep;37 Suppl 2:S5-15. Review.

PMID:
21246930
44.

A new role for heme, facilitating release of iron from the bacterioferritin iron biomineral.

Yasmin S, Andrews SC, Moore GR, Le Brun NE.

J Biol Chem. 2011 Feb 4;286(5):3473-83. doi: 10.1074/jbc.M110.175034. Epub 2010 Nov 23.

45.

Pathological basis of diffusely abnormal white matter: insights from magnetic resonance imaging and histology.

Laule C, Vavasour IM, Leung E, Li DK, Kozlowski P, Traboulsee AL, Oger J, Mackay AL, Moore GR.

Mult Scler. 2011 Feb;17(2):144-50. doi: 10.1177/1352458510384008. Epub 2010 Oct 21.

PMID:
20965961
46.

Low rates of free human papillomavirus vaccine uptake among young women.

Moore GR, Crosby RA, Young A, Charnigo R.

Sex Health. 2010 Sep;7(3):287-90. doi: 10.1071/SH09136.

PMID:
20719216
47.

The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction.

Meenan NA, Sharma A, Fleishman SJ, Macdonald CJ, Morel B, Boetzel R, Moore GR, Baker D, Kleanthous C.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10080-5. doi: 10.1073/pnas.0910756107. Epub 2010 May 17.

48.

Characterisation of the interaction of colicin A with its co-receptor TolA.

Hecht O, Zhang Y, Li C, Penfold CN, James R, Moore GR.

FEBS Lett. 2010 Jun 3;584(11):2249-52. doi: 10.1016/j.febslet.2010.04.061. Epub 2010 Apr 29.

49.

Iron core mineralisation in prokaryotic ferritins.

Le Brun NE, Crow A, Murphy ME, Mauk AG, Moore GR.

Biochim Biophys Acta. 2010 Aug;1800(8):732-44. doi: 10.1016/j.bbagen.2010.04.002. Epub 2010 Apr 11. Review.

PMID:
20388533
50.

Thalamic stimulation in multiple sclerosis: evidence for a 'demyelinative thalamotomy'.

Moore GR, Vitali AM, Leung E, Laule C, Kozlowski P, Mackay AL, Honey CR.

Mult Scler. 2009 Nov;15(11):1311-21. doi: 10.1177/1352458509345914. Epub 2009 Oct 15.

PMID:
19833687

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