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Items: 17


Ultra-Sensitive Mutation Detection and Genome-Wide DNA Copy Number Reconstruction by Error-Corrected Circulating Tumor DNA Sequencing.

Mansukhani S, Barber LJ, Kleftogiannis D, Moorcraft SY, Davidson M, Woolston A, Proszek PZ, Griffiths B, Fenwick K, Herman B, Matthews N, O'Leary B, Hulkki S, Gonzalez De Castro D, Patel A, Wotherspoon A, Okachi A, Rana I, Begum R, Davies MN, Powles T, von Loga K, Hubank M, Turner N, Watkins D, Chau I, Cunningham D, Lise S, Starling N, Gerlinger M.

Clin Chem. 2018 Aug 27. pii: clinchem.2018.289629. doi: 10.1373/clinchem.2018.289629. [Epub ahead of print]


Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.

Vlachogiannis G, Hedayat S, Vatsiou A, Jamin Y, Fernández-Mateos J, Khan K, Lampis A, Eason K, Huntingford I, Burke R, Rata M, Koh DM, Tunariu N, Collins D, Hulkki-Wilson S, Ragulan C, Spiteri I, Moorcraft SY, Chau I, Rao S, Watkins D, Fotiadis N, Bali M, Darvish-Damavandi M, Lote H, Eltahir Z, Smyth EC, Begum R, Clarke PA, Hahne JC, Dowsett M, de Bono J, Workman P, Sadanandam A, Fassan M, Sansom OJ, Eccles S, Starling N, Braconi C, Sottoriva A, Robinson SP, Cunningham D, Valeri N.

Science. 2018 Feb 23;359(6378):920-926. doi: 10.1126/science.aao2774.


Investigating the feasibility of tumour molecular profiling in gastrointestinal malignancies in routine clinical practice.

Moorcraft SY, Gonzalez de Castro D, Cunningham D, Jones T, Walker BA, Peckitt C, Yuan LC, Frampton M, Begum R, Eltahir Z, Wotherspoon A, Teixeira Mendes LS, Hulkki Wilson S, Gillbanks A, Baratelli C, Fotiadis N, Patel A, Braconi C, Valeri N, Gerlinger M, Rao S, Watkins D, Chau I, Starling N.

Ann Oncol. 2018 Jan 1;29(1):230-236. doi: 10.1093/annonc/mdx631.


Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment.

Moorcraft SY, Jones T, Walker BA, Ladas G, Kalaitzaki E, Yuan L, Begum R, Eltahir Z, Wotherspoon A, Montero-Fernandez A, Teixeira Mendes LS, Gonzalez de Castro D, Wilson SH, Proszek P, To YM, Hawkes E, Roy A, Cunningham D, Rao S, Watkins D, Starling N, Bowcock AM, Chau I.

Oncotarget. 2017 Apr 11;8(39):64999-65008. doi: 10.18632/oncotarget.17048. eCollection 2017 Sep 12.


Attitudes of Patients With Gastrointestinal Cancers Toward Research Biopsies.

Moorcraft SY, Begum R, Cunningham D, Peckitt C, Baratelli C, Gillbanks A, Rogers P, Nwokorie V, Chau I, Watkins D, Starling N.

Clin Colorectal Cancer. 2017 Sep;16(3):e181-e189. doi: 10.1016/j.clcc.2016.09.008. Epub 2016 Oct 6.


FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis.

Suker M, Beumer BR, Sadot E, Marthey L, Faris JE, Mellon EA, El-Rayes BF, Wang-Gillam A, Lacy J, Hosein PJ, Moorcraft SY, Conroy T, Hohla F, Allen P, Taieb J, Hong TS, Shridhar R, Chau I, van Eijck CH, Koerkamp BG.

Lancet Oncol. 2016 Jun;17(6):801-810. doi: 10.1016/S1470-2045(16)00172-8. Epub 2016 May 6. Review.


Characterising timing and pattern of relapse following surgery for localised oesophagogastric adenocarcinoma: a retrospective study.

Moorcraft SY, Fontana E, Cunningham D, Peckitt C, Waddell T, Smyth EC, Allum W, Thompson J, Rao S, Watkins D, Starling N, Chau I.

BMC Cancer. 2016 Feb 17;16:112. doi: 10.1186/s12885-016-2145-0.


Does cancer research focus on areas of importance to patients?

Moorcraft SY, Sangha A, Peckitt C, Sanchez R, Lee M, Pattison N, Wiseman T.

Ecancermedicalscience. 2016 Jan 7;10:ed51. doi: 10.3332/ecancer.2016.ed51. eCollection 2016.


Patients' willingness to participate in clinical trials and their views on aspects of cancer research: results of a prospective patient survey.

Moorcraft SY, Marriott C, Peckitt C, Cunningham D, Chau I, Starling N, Watkins D, Rao S.

Trials. 2016 Jan 9;17:17. doi: 10.1186/s13063-015-1105-3.


Management of resectable colorectal lung metastases.

Moorcraft SY, Ladas G, Bowcock A, Chau I.

Clin Exp Metastasis. 2016 Mar;33(3):285-96. doi: 10.1007/s10585-015-9774-6. Epub 2015 Dec 10. Review.


Understanding next generation sequencing in oncology: A guide for oncologists.

Moorcraft SY, Gonzalez D, Walker BA.

Crit Rev Oncol Hematol. 2015 Dec;96(3):463-74. doi: 10.1016/j.critrevonc.2015.06.007. Epub 2015 Jun 29. Review.


Potential role of rilotumumab in the treatment of gastric cancer.

Waddell T, Moorcraft SY, Cunningham D.

Immunotherapy. 2014;6(12):1243-53. doi: 10.2217/imt.14.91. Review.


FOLFIRINOX for locally advanced or metastatic pancreatic ductal adenocarcinoma: the Royal Marsden experience.

Moorcraft SY, Khan K, Peckitt C, Watkins D, Rao S, Cunningham D, Chau I.

Clin Colorectal Cancer. 2014 Dec;13(4):232-8. doi: 10.1016/j.clcc.2014.09.005. Epub 2014 Sep 21.


Investigational therapies targeting the ErbB family in oesophagogastric cancer.

Moorcraft SY, Chau I.

Expert Opin Investig Drugs. 2014 Oct;23(10):1349-63. doi: 10.1517/13543784.2014.930126. Epub 2014 Jun 20. Review.


Adjuvant or neoadjuvant therapy for operable esophagogastric cancer?

Moorcraft SY, Smyth EC, Cunningham D.

Gastric Cancer. 2015 Jan;18(1):1-10. doi: 10.1007/s10120-014-0356-0. Epub 2014 Mar 18. Review.


The role of personalized medicine in metastatic colorectal cancer: an evolving landscape.

Moorcraft SY, Smyth EC, Cunningham D.

Therap Adv Gastroenterol. 2013 Sep;6(5):381-95. doi: 10.1177/1756283X13491797.


Patupilone in patients with pretreated metastatic/locally recurrent colorectal cancer: results of the Phase II CINATRA trial.

Moorcraft SY, Chau I, Peckitt C, Cunningham D, Rao S, Yim KL, Walther A, Jackson CG, Stamp G, Webb J, Smith G, Gillbanks A, Swanton C.

Invest New Drugs. 2013 Oct;31(5):1339-44. doi: 10.1007/s10637-013-9990-3. Epub 2013 Jun 26.


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