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Items: 19


Can Contrast-Enhanced Sonography Detect Bowel Wall Fibrosis in Mixed Inflammatory and Fibrotic Crohn Disease Lesions in an Animal Model?

Dillman JR, Rubin JM, Johnson LA, Moons DS, Higgins PD.

J Ultrasound Med. 2017 Mar;36(3):523-530. doi: 10.7863/ultra.16.04064. Epub 2017 Jan 10.


Optimisation of Intestinal Fibrosis and Survival in the Mouse S. Typhimurium Model for Anti-fibrotic Drug Discovery and Preclinical Applications.

Johnson LA, Rodansky ES, Moons DS, Larsen SD, Neubig RR, Higgins PDR.

J Crohns Colitis. 2017 Jun 1;11(6):724-736. doi: 10.1093/ecco-jcc/jjw210.


Characterizing intestinal inflammation and fibrosis in Crohn's disease by photoacoustic imaging: feasibility study.

Lei H, Johnson LA, Liu S, Moons DS, Ma T, Zhou Q, Rice MD, Ni J, Wang X, Higgins PD, Xu G.

Biomed Opt Express. 2016 Jun 27;7(7):2837-48. doi: 10.1364/BOE.7.002837. eCollection 2016 Jul 1.


Comparison of noncontrast MRI magnetization transfer and T2 -Weighted signal intensity ratios for detection of bowel wall fibrosis in a Crohn's disease animal model.

Dillman JR, Swanson SD, Johnson LA, Moons DS, Adler J, Stidham RW, Higgins PD.

J Magn Reson Imaging. 2015 Sep;42(3):801-10. doi: 10.1002/jmri.24815. Epub 2014 Dec 13.


Ultrasound shear wave elastography helps discriminate low-grade from high-grade bowel wall fibrosis in ex vivo human intestinal specimens.

Dillman JR, Stidham RW, Higgins PD, Moons DS, Johnson LA, Keshavarzi NR, Rubin JM.

J Ultrasound Med. 2014 Dec;33(12):2115-23. doi: 10.7863/ultra.33.12.2115.


CD73 (ecto-5'-nucleotidase) hepatocyte levels differ across mouse strains and contribute to mallory-denk body formation.

Snider NT, Griggs NW, Singla A, Moons DS, Weerasinghe SV, Lok AS, Ruan C, Burant CF, Conjeevaram HS, Omary MB.

Hepatology. 2013 Nov;58(5):1790-800. doi: 10.1002/hep.26525. Epub 2013 Aug 26.


US elastography-derived shear wave velocity helps distinguish acutely inflamed from fibrotic bowel in a Crohn disease animal model.

Dillman JR, Stidham RW, Higgins PD, Moons DS, Johnson LA, Rubin JM.

Radiology. 2013 Jun;267(3):757-66. doi: 10.1148/radiol.13121775. Epub 2013 Feb 11.


The hypoxia-inducible factor-C/EBPα axis controls ethanol-mediated hepcidin repression.

Anderson ER, Taylor M, Xue X, Martin A, Moons DS, Omary MB, Shah YM.

Mol Cell Biol. 2012 Oct;32(19):4068-77. doi: 10.1128/MCB.00723-12. Epub 2012 Aug 6.


Oxidative stress, Nrf2 and keratin up-regulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria.

Singla A, Moons DS, Snider NT, Wagenmaker ER, Jayasundera VB, Omary MB.

Hepatology. 2012 Jul;56(1):322-31. doi: 10.1002/hep.25664. Epub 2012 Apr 25.


Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with Crohn's disease.

Stidham RW, Xu J, Johnson LA, Kim K, Moons DS, McKenna BJ, Rubin JM, Higgins PD.

Gastroenterology. 2011 Sep;141(3):819-826.e1. doi: 10.1053/j.gastro.2011.07.027. Epub 2011 Jul 23.


Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: impact of a "Top-Down" approach to intestinal fibrosis in mice.

Johnson LA, Luke A, Sauder K, Moons DS, Horowitz JC, Higgins PD.

Inflamm Bowel Dis. 2012 Mar;18(3):460-71. doi: 10.1002/ibd.21812. Epub 2011 Jul 14.


Fibrinogen-γ proteolysis and solubility dynamics during apoptotic mouse liver injury: heparin prevents and treats liver damage.

Weerasinghe SV, Moons DS, Altshuler PJ, Shah YM, Omary MB.

Hepatology. 2011 Apr;53(4):1323-32. doi: 10.1002/hep.24203.


Rapamycin inhibits growth factor-induced cell cycle regulation in pancreatic beta cells.

Aronovitz A, Josefson J, Fisher A, Newman M, Hughes E, Chen F, Moons DS, Kiyokawa H, Lowe WL Jr.

J Investig Med. 2008 Dec;56(8):985-96. doi: 10.2310/JIM.0b013e31818ce763.


Cdk4 is indispensable for postnatal proliferation of the anterior pituitary.

Jirawatnotai S, Aziyu A, Osmundson EC, Moons DS, Zou X, Kineman RD, Kiyokawa H.

J Biol Chem. 2004 Dec 3;279(49):51100-6. Epub 2004 Sep 28.


The cyclin-dependent kinase inhibitors p27Kip1 and p21Cip1 cooperate to restrict proliferative life span in differentiating ovarian cells.

Jirawatnotai S, Moons DS, Stocco CO, Franks R, Hales DB, Gibori G, Kiyokawa H.

J Biol Chem. 2003 May 9;278(19):17021-7. Epub 2003 Feb 27.


Cdk4 deficiency inhibits skin tumor development but does not affect normal keratinocyte proliferation.

Rodriguez-Puebla ML, Miliani de Marval PL, LaCava M, Moons DS, Kiyokawa H, Conti CJ.

Am J Pathol. 2002 Aug;161(2):405-11.


Pituitary hypoplasia and lactotroph dysfunction in mice deficient for cyclin-dependent kinase-4.

Moons DS, Jirawatnotai S, Parlow AF, Gibori G, Kineman RD, Kiyokawa H.

Endocrinology. 2002 Aug;143(8):3001-8.


Intact follicular maturation and defective luteal function in mice deficient for cyclin- dependent kinase-4.

Moons DS, Jirawatnotai S, Tsutsui T, Franks R, Parlow AF, Hales DB, Gibori G, Fazleabas AT, Kiyokawa H.

Endocrinology. 2002 Feb;143(2):647-54.


Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity.

Tsutsui T, Hesabi B, Moons DS, Pandolfi PP, Hansel KS, Koff A, Kiyokawa H.

Mol Cell Biol. 1999 Oct;19(10):7011-9.

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