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Items: 48

1.

Whole Blood Targeted Bisulfite Sequencing Validates Differential Methylation in C6ORF10 gene of Patients with Rheumatoid Arthritis.

Anaparti V, Agarwal P, Smolik I, Mookherjee N, Elgabalawy H.

J Rheumatol. 2019 Nov 1. pii: jrheum.190376. doi: 10.3899/jrheum.190376. [Epub ahead of print]

PMID:
31676691
2.

Polymorphisms in the P2X7 receptor, and differential expression of Toll-like receptor-mediated cytokines and defensins, in a Canadian Indigenous group.

Semple C, Choi KG, Kroeker A, Denechezhe L, Orr P, Mookherjee N, Larcombe L.

Sci Rep. 2019 Oct 2;9(1):14204. doi: 10.1038/s41598-019-50596-0.

3.

Circulating levels of free 25(OH)D increase at the onset of rheumatoid arthritis.

Anaparti V, Meng X, Hemshekhar M, Smolik I, Mookherjee N, El-Gabalawy H.

PLoS One. 2019 Sep 26;14(9):e0219109. doi: 10.1371/journal.pone.0219109. eCollection 2019.

4.

Immunomodulatory Functions of the Human Cathelicidin LL-37 (aa 13-31)-Derived Peptides are Associated with Predicted α-Helical Propensity and Hydrophobic Index.

Hemshekhar M, Faiyaz S, Choi KG, Krokhin OV, Mookherjee N.

Biomolecules. 2019 Sep 18;9(9). pii: E501. doi: 10.3390/biom9090501.

5.

Antimicrobial Host Defence Peptides: Immunomodulatory Functions and Translational Prospects.

van der Does AM, Hiemstra PS, Mookherjee N.

Adv Exp Med Biol. 2019;1117:149-171. doi: 10.1007/978-981-13-3588-4_10. Review.

PMID:
30980358
7.

Cytokines IL-17, TNF and IFN-γ Alter the Expression of Antimicrobial Peptides and Proteins Disparately: A Targeted Proteomics Analysis using SOMAscan Technology.

Altieri A, Piyadasa H, Recksiedler B, Spicer V, Mookherjee N.

Vaccines (Basel). 2018 Aug 7;6(3). pii: E51. doi: 10.3390/vaccines6030051.

8.

Immunomodulatory innate defence regulator (IDR) peptide alleviates airway inflammation and hyper-responsiveness.

Piyadasa H, Hemshekhar M, Altieri A, Basu S, van der Does AM, Halayko AJ, Hiemstra PS, Mookherjee N.

Thorax. 2018 Oct;73(10):908-917. doi: 10.1136/thoraxjnl-2017-210739. Epub 2018 May 31.

PMID:
29853649
9.

Inhaled diesel exhaust alters the allergen-induced bronchial secretome in humans.

Mookherjee N, Piyadasa H, Ryu MH, Rider CF, Ezzati P, Spicer V, Carlsten C.

Eur Respir J. 2018 Jan 25;51(1). pii: 1701385. doi: 10.1183/13993003.01385-2017. Print 2018 Jan.

10.

Inhaled Diesel Exhaust Decreases the Antimicrobial Peptides α-Defensin and S100A7 in Human Bronchial Secretions.

Piyadasa H, Hemshekhar M, Carlsten C, Mookherjee N.

Am J Respir Crit Care Med. 2018 May 15;197(10):1358-1361. doi: 10.1164/rccm.201708-1714LE. No abstract available.

PMID:
29244524
11.

Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects.

Anaparti V, Smolik I, Meng X, Spicer V, Mookherjee N, El-Gabalawy H.

Arthritis Res Ther. 2017 Nov 10;19(1):249. doi: 10.1186/s13075-017-1459-x.

12.

Buprenorphine Alters Inflammatory and Oxidative Stress Molecular Markers in Arthritis.

Hemshekhar M, Anaparti V, Hitchon C, Mookherjee N.

Mediators Inflamm. 2017;2017:2515408. doi: 10.1155/2017/2515408. Epub 2017 May 9.

13.

Functions of Cationic Host Defense Peptides in Immunity.

Hemshekhar M, Anaparti V, Mookherjee N.

Pharmaceuticals (Basel). 2016 Jul 4;9(3). pii: E40. doi: 10.3390/ph9030040. Review.

14.

Biosignature for airway inflammation in a house dust mite-challenged murine model of allergic asthma.

Piyadasa H, Altieri A, Basu S, Schwartz J, Halayko AJ, Mookherjee N.

Biol Open. 2016 Jan 6;5(2):112-21. doi: 10.1242/bio.014464.

15.

The biochemical signatures of stress: A preliminary analysis of osteocalcin concentrations and macroscopic skeletal changes associated with stress in the 13th - 17th centuries black friars population.

Scott AB, Choi KY, Mookherjee N, Hoppa RD, Larcombe LA.

Am J Phys Anthropol. 2016 Apr;159(4):596-606. doi: 10.1002/ajpa.22915. Epub 2015 Dec 18.

PMID:
26678538
16.

Vitamin D, serum 25(OH)D, LL-37 and polymorphisms in a Canadian First Nation population with endemic tuberculosis.

Larcombe L, Mookherjee N, Slater J, Slivinski C, Dantouze J, Singer M, Whaley C, Denechezhe L, Matyas S, Decter K, Turner-Brannen E, Ramsey C, Nickerson P, Orr P.

Int J Circumpolar Health. 2015 Aug 19;74:28952. doi: 10.3402/ijch.v74.28952. eCollection 2015.

17.

Amphiphilic tobramycins with immunomodulatory properties.

Guchhait G, Altieri A, Gorityala B, Yang X, Findlay B, Zhanel GG, Mookherjee N, Schweizer F.

Angew Chem Int Ed Engl. 2015 May 18;54(21):6278-82. doi: 10.1002/anie.201500598. Epub 2015 Apr 1.

PMID:
25847672
18.

Vitamin D, serum 25(OH)D, LL-37 and polymorphisms in a Canadian First Nation population with endemic tuberculosis.

Larcombe L, Mookherjee N, Slater J, Slivinski C, Dantouze J, Singer M, Whaley C, Denechezhe L, Matyas S, Decter K, Turner-Brannen E, Ramsey C, Nickerson P, Orr P.

Int J Circumpolar Health. 2015 Jan;74(1):28952. doi: 10.3402/ijch.v74.28952.

PMID:
28417792
19.

Structure-activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity.

Domalaon R, Yang X, O'Neil J, Zhanel GG, Mookherjee N, Schweizer F.

Amino Acids. 2014 Nov;46(11):2517-30. doi: 10.1007/s00726-014-1806-z. Epub 2014 Jul 29.

PMID:
25069750
20.

Human cathelicidin LL-37 and its derivative IG-19 regulate interleukin-32-induced inflammation.

Choi KY, Napper S, Mookherjee N.

Immunology. 2014 Sep;143(1):68-80. doi: 10.1111/imm.12291.

21.

High degree of correlation between whole blood and PBMC expression levels of miR-155 and miR-146a in healthy controls and rheumatoid arthritis patients.

Mookherjee N, El-Gabalawy HS.

J Immunol Methods. 2013 Dec 31;400-401:106-10. doi: 10.1016/j.jim.2013.10.001. Epub 2013 Oct 11.

PMID:
24120842
22.

Human cathelicidin LL-37-derived peptide IG-19 confers protection in a murine model of collagen-induced arthritis.

Chow LN, Choi KY, Piyadasa H, Bossert M, Uzonna J, Klonisch T, Mookherjee N.

Mol Immunol. 2014 Feb;57(2):86-92. doi: 10.1016/j.molimm.2013.08.011. Epub 2013 Oct 1.

PMID:
24091294
23.

Ultrashort cationic lipopeptides and lipopeptoids selectively induce cytokine production in macrophages.

Findlay B, Mookherjee N, Schweizer F.

PLoS One. 2013;8(2):e54280. doi: 10.1371/journal.pone.0054280. Epub 2013 Feb 4.

24.

Vitamin D in a northern Canadian first nation population: dietary intake, serum concentrations and functional gene polymorphisms.

Larcombe L, Mookherjee N, Slater J, Slivinski C, Singer M, Whaley C, Denechezhe L, Matyas S, Turner-Brannen E, Nickerson P, Orr P.

PLoS One. 2012;7(11):e49872. doi: 10.1371/journal.pone.0049872. Epub 2012 Nov 21.

25.

Effect of vitamin D supplementation on Mycobacterium tuberculosis-induced innate immune responses in a Canadian Dené First Nations cohort.

Larcombe L, Orr P, Turner-Brannen E, Slivinski CR, Nickerson PW, Mookherjee N.

PLoS One. 2012;7(7):e40692. doi: 10.1371/journal.pone.0040692. Epub 2012 Jul 16.

26.

Cationic host defence peptides: multifaceted role in immune modulation and inflammation.

Choi KY, Chow LN, Mookherjee N.

J Innate Immun. 2012;4(4):361-70. doi: 10.1159/000336630. Epub 2012 Mar 14. Review.

27.

Multiple immune-modulatory functions of cathelicidin host defense peptides.

Choi KY, Mookherjee N.

Front Immunol. 2012 Jun 11;3:149. doi: 10.3389/fimmu.2012.00149. eCollection 2012. No abstract available.

28.

Defining TNF-α and IL-1β induced nascent proteins: combining bio-orthogonal non-canonical amino acid tagging and proteomics.

Choi KY, Lippert DN, Ezzatti P, Mookherjee N.

J Immunol Methods. 2012 Aug 31;382(1-2):189-95. doi: 10.1016/j.jim.2012.06.003. Epub 2012 Jun 12.

PMID:
22698787
29.

Defining the mechanism of action of herbal therapies in rheumatoid arthritis: is this the road to clinical development and acceptance?

Mookherjee N, El-Gabalawy H.

J Rheumatol. 2011 Sep;38(9):1817-9. doi: 10.3899/jrheum.110823. No abstract available.

PMID:
21885502
30.

Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts.

Turner-Brannen E, Choi KY, Lippert DN, Cortens JP, Hancock RE, El-Gabalawy H, Mookherjee N.

Arthritis Res Ther. 2011 Aug 11;13(4):R129. doi: 10.1186/ar3440.

31.

Inflammatory cytokines IL-32 and IL-17 have common signaling intermediates despite differential dependence on TNF-receptor 1.

Turner-Brannen E, Choi KY, Arsenault R, El-Gabalawy H, Napper S, Mookherjee N.

J Immunol. 2011 Jun 15;186(12):7127-35. doi: 10.4049/jimmunol.1002306. Epub 2011 May 20.

32.

Intracellular receptor for human host defense peptide LL-37 in monocytes.

Mookherjee N, Lippert DN, Hamill P, Falsafi R, Nijnik A, Kindrachuk J, Pistolic J, Gardy J, Miri P, Naseer M, Foster LJ, Hancock RE.

J Immunol. 2009 Aug 15;183(4):2688-96. doi: 10.4049/jimmunol.0802586. Epub 2009 Jul 15.

33.

The human host defense peptide LL-37 induces apoptosis in a calpain- and apoptosis-inducing factor-dependent manner involving Bax activity.

Mader JS, Mookherjee N, Hancock RE, Bleackley RC.

Mol Cancer Res. 2009 May;7(5):689-702. doi: 10.1158/1541-7786.MCR-08-0274. Epub 2009 May 12.

34.

Systems biology evaluation of immune responses induced by human host defence peptide LL-37 in mononuclear cells.

Mookherjee N, Hamill P, Gardy J, Blimkie D, Falsafi R, Chikatamarla A, Arenillas DJ, Doria S, Kollmann TR, Hancock RE.

Mol Biosyst. 2009 May;5(5):483-96. doi: 10.1039/b813787k. Epub 2009 Mar 19.

PMID:
19381363
35.

Host defense peptide LL-37, in synergy with inflammatory mediator IL-1beta, augments immune responses by multiple pathways.

Yu J, Mookherjee N, Wee K, Bowdish DM, Pistolic J, Li Y, Rehaume L, Hancock RE.

J Immunol. 2007 Dec 1;179(11):7684-91.

36.

Cathelicidins and functional analogues as antisepsis molecules.

Mookherjee N, Rehaume LM, Hancock RE.

Expert Opin Ther Targets. 2007 Aug;11(8):993-1004. Review.

PMID:
17665972
37.

An anti-infective peptide that selectively modulates the innate immune response.

Scott MG, Dullaghan E, Mookherjee N, Glavas N, Waldbrook M, Thompson A, Wang A, Lee K, Doria S, Hamill P, Yu JJ, Li Y, Donini O, Guarna MM, Finlay BB, North JR, Hancock RE.

Nat Biotechnol. 2007 Apr;25(4):465-72. Epub 2007 Mar 25.

PMID:
17384586
38.

Nucleic acids exert a sequence-independent cooperative effect on sequence-dependent activation of Toll-like receptor 9.

Kindrachuk J, Potter JE, Brownlie R, Ficzycz AD, Griebel PJ, Mookherjee N, Mutwiri GK, Babiuk LA, Napper S.

J Biol Chem. 2007 May 11;282(19):13944-53. Epub 2007 Mar 13.

39.

Cationic host defence peptides: innate immune regulatory peptides as a novel approach for treating infections.

Mookherjee N, Hancock RE.

Cell Mol Life Sci. 2007 Apr;64(7-8):922-33. Review.

PMID:
17310278
40.

Bovine and human cathelicidin cationic host defense peptides similarly suppress transcriptional responses to bacterial lipopolysaccharide.

Mookherjee N, Wilson HL, Doria S, Popowych Y, Falsafi R, Yu JJ, Li Y, Veatch S, Roche FM, Brown KL, Brinkman FS, Hokamp K, Potter A, Babiuk LA, Griebel PJ, Hancock RE.

J Leukoc Biol. 2006 Dec;80(6):1563-74. Epub 2006 Aug 30.

PMID:
16943385
41.

Host defence peptides from invertebrates--emerging antimicrobial strategies.

Hancock RE, Brown KL, Mookherjee N.

Immunobiology. 2006;211(4):315-22. Epub 2006 Apr 17. Review.

PMID:
16697922
42.

Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.

Mookherjee N, Brown KL, Bowdish DM, Doria S, Falsafi R, Hokamp K, Roche FM, Mu R, Doho GH, Pistolic J, Powers JP, Bryan J, Brinkman FS, Hancock RE.

J Immunol. 2006 Feb 15;176(4):2455-64.

43.

Bovine toll-like receptor 9: a comparative analysis of molecular structure, function and expression.

Griebel PJ, Brownlie R, Manuja A, Nichani A, Mookherjee N, Popowych Y, Mutwiri G, Hecker R, Babiuk LA.

Vet Immunol Immunopathol. 2005 Oct 18;108(1-2):11-6. Review.

PMID:
16098606
44.

TLR9-/- and TLR9+/+ mice display similar immune responses to a DNA vaccine.

Babiuk S, Mookherjee N, Pontarollo R, Griebel P, van Drunen Littel-van den Hurk S, Hecker R, Babiuk L.

Immunology. 2004 Sep;113(1):114-20.

45.
46.
47.

Phosphorylation of a major GPI-anchored surface protein of Trypanosoma brucei during transport to the plasma membrane.

Bütikofer P, Vassella E, Ruepp S, Boschung M, Civenni G, Seebeck T, Hemphill A, Mookherjee N, Pearson TW, Roditi I.

J Cell Sci. 1999 Jun;112 ( Pt 11):1785-95.

48.

Microbiological evaluation of women with bad obstetrics history.

Mookherjee N, Gogate A, Shah PK.

Indian J Med Res. 1995 Mar;101:103-7.

PMID:
7751036

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