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Items: 1 to 50 of 134

1.

Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism.

Mooijaart SP, Du Puy RS, Stott DJ, Kearney PM, Rodondi N, Westendorp RGJ, den Elzen WPJ, Postmus I, Poortvliet RKE, van Heemst D, van Munster BC, Peeters RP, Ford I, Kean S, Messow CM, Blum MR, Collet TH, Watt T, Dekkers OM, Jukema JW, Smit JWA, Langhorne P, Gussekloo J.

JAMA. 2019 Oct 30:1-11. doi: 10.1001/jama.2019.17274. [Epub ahead of print]

PMID:
31664429
2.

Recommendations for (Discontinuation of) Statin Treatment in Older Adults: Review of Guidelines.

van der Ploeg MA, Floriani C, Achterberg WP, Bogaerts JMK, Gussekloo J, Mooijaart SP, Streit S, Poortvliet RKE, Drewes YM.

J Am Geriatr Soc. 2019 Oct 30. doi: 10.1111/jgs.16219. [Epub ahead of print] Review.

PMID:
31663610
3.

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals.

Deelen J, Kettunen J, Fischer K, van der Spek A, Trompet S, Kastenmüller G, Boyd A, Zierer J, van den Akker EB, Ala-Korpela M, Amin N, Demirkan A, Ghanbari M, van Heemst D, Ikram MA, van Klinken JB, Mooijaart SP, Peters A, Salomaa V, Sattar N, Spector TD, Tiemeier H, Verhoeven A, Waldenberger M, Würtz P, Davey Smith G, Metspalu A, Perola M, Menni C, Geleijnse JM, Drenos F, Beekman M, Jukema JW, van Duijn CM, Slagboom PE.

Nat Commun. 2019 Aug 20;10(1):3346. doi: 10.1038/s41467-019-11311-9.

4.

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium.

van der Spek A, Broer L, Draisma HHM, Pool R, Albrecht E, Beekman M, Mangino M, Raag M, Nyholt DR, Dharuri HK, Codd V, Amin N, de Geus EJC, Deelen J, Demirkan A, Yet I, Fischer K, Haller T, Henders AK, Isaacs A, Medland SE, Montgomery GW, Mooijaart SP, Strauch K, Suchiman HED, Vaarhorst AAM, van Heemst D, Wang-Sattler R, Whitfield JB, Willemsen G, Wright MJ, Martin NG, Samani NJ, Metspalu A, Eline Slagboom P, Spector TD, Boomsma DI, van Duijn CM, Gieger C.

Sci Rep. 2019 Aug 12;9(1):11623. doi: 10.1038/s41598-019-47282-6.

5.

Associations of Elevated Antithyroperoxidase Antibodies with Thyroid Function, Survival, Functioning, and Depressive Symptoms in the Oldest Old: The Leiden 85-plus Study.

Du Puy RS, Poortvliet RKE, Snel M, den Elzen WPJ, Ballieux BEPB, Dekkers OM, Mooijaart SP, Gussekloo J.

Thyroid. 2019 Sep;29(9):1201-1208. doi: 10.1089/thy.2019.0129.

PMID:
31382845
6.

Vital signs and impaired cognition in older emergency department patients: The APOP study.

Lucke JA, de Gelder J, Blomaard LC, Heringhaus C, Alsma J, Klein Nagelvoort Schuit SCE, Brink A, Anten S, Blauw GJ, de Groot B, Mooijaart SP.

PLoS One. 2019 Jun 20;14(6):e0218596. doi: 10.1371/journal.pone.0218596. eCollection 2019.

7.

The association between intravenous fluid resuscitation and mortality in older emergency department patients with suspected infection.

Ko SY, Esteve Cuevas LM, Willeboer M, Ansems A, Blomaard LC, Lucke JA, Mooijaart SP, de Groot B.

Int J Emerg Med. 2019 Jan 5;12(1):1. doi: 10.1186/s12245-018-0219-2.

8.

Systematic Review: Components of a Comprehensive Geriatric Assessment in Inflammatory Bowel Disease-A Potentially Promising but Often Neglected Risk Stratification.

Asscher VER, Lee-Kong FVY, Kort ED, van Deudekom FJ, Mooijaart SP, Maljaars PWJ.

J Crohns Colitis. 2019 Oct 28;13(11):1418-1432. doi: 10.1093/ecco-jcc/jjz082.

9.

Geriatric assessment and 1-year mortality in older patients with cancer in the head and neck region: A cohort study.

van Deudekom FJ, van der Velden LA, Zijl WH, Schimberg AS, Langeveld AP, Slingerland M, Blauw GJ, Mooijaart SP.

Head Neck. 2019 Aug;41(8):2477-2483. doi: 10.1002/hed.25714. Epub 2019 Feb 28.

10.

Geriatric emergency medicine: time for a new approach on a European level.

Mooijaart SP, Lucke JA, Brabrand M, Conroy S, Nickel CH.

Eur J Emerg Med. 2019 Apr;26(2):75-76. doi: 10.1097/MEJ.0000000000000594. No abstract available.

PMID:
30801429
11.

Acute care assessment of older adults living with frailty.

Quinn TJ, Mooijaart SP, Gallacher K, Burton JK.

BMJ. 2019 Jan 31;364:l13. doi: 10.1136/bmj.l13. No abstract available.

PMID:
30705024
12.

CAM-ICU may not be the optimal screening tool for early delirium screening in older emergency department patients: a prospective cohort study.

Lucke JA, De Gelder J, Blomaard LC, Fogteloo AJ, Alsma J, Schuit SCE, Brink A, De Groot B, Blauw GJ, Mooijaart SP.

Eur J Emerg Med. 2019 Dec;26(6):428-432. doi: 10.1097/MEJ.0000000000000587.

PMID:
30585854
13.

Spatial QRS-T Angle and Cognitive Decline in Older Subjects.

Mahinrad S, Ferguson I, Macfarlane PW, Clark EN, Stott DJ, Ford I, Mooijaart SP, Trompet S, van Heemst D, Jukema JW, Sabayan B.

J Alzheimers Dis. 2019;67(1):279-289. doi: 10.3233/JAD-180633.

PMID:
30584139
14.

Erythrocyte sedimentation rate as an independent prognostic marker for mortality: a prospective population-based cohort study.

Fest J, Ruiter R, Mooijaart SP, Ikram MA, van Eijck CHJ, Stricker BH.

J Intern Med. 2019 Mar;285(3):341-348. doi: 10.1111/joim.12853. Epub 2018 Dec 9.

PMID:
30537394
15.

Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over.

Du Puy RS, Postmus I, Stott DJ, Blum MR, Poortvliet RKE, Den Elzen WPJ, Peeters RP, van Munster BC, Wolffenbuttel BHR, Westendorp RGJ, Kearney PM, Ford I, Kean S, Messow CM, Watt T, Jukema JW, Dekkers OM, Smit JWA, Rodondi N, Gussekloo J, Mooijaart SP.

BMC Endocr Disord. 2018 Sep 19;18(1):67. doi: 10.1186/s12902-018-0285-8.

16.

The Six-Item Cognitive Impairment Test Is Associated with Adverse Outcomes in Acutely Hospitalized Older Patients: A Prospective Cohort Study.

Lucke JA, van der Mast RC, de Gelder J, Heim N, de Groot B, Mooijaart SP, Blauw GJ.

Dement Geriatr Cogn Dis Extra. 2018 Jul 12;8(2):259-267. doi: 10.1159/000490240. eCollection 2018 May-Aug.

17.

Clinical aspects of thyroid function during ageing.

Chaker L, Cappola AR, Mooijaart SP, Peeters RP.

Lancet Diabetes Endocrinol. 2018 Sep;6(9):733-742. doi: 10.1016/S2213-8587(18)30028-7. Epub 2018 Jul 17. Review.

PMID:
30017801
18.

Optimization of the APOP screener to predict functional decline or mortality in older emergency department patients: Cross-validation in four prospective cohorts.

de Gelder J, Lucke JA, Blomaard LC, Booijen AM, Fogteloo AJ, Anten S, Steyerberg EW, Alsma J, Klein Nagelvoort Schuit SCE, Brink A, de Groot B, Blauw GJ, Mooijaart SP.

Exp Gerontol. 2018 Sep;110:253-259. doi: 10.1016/j.exger.2018.06.015. Epub 2018 Jun 20.

PMID:
29935293
19.

High Adiposity Is Associated With Higher Nocturnal and Diurnal Glycaemia, but Not With Glycemic Variability in Older Individuals Without Diabetes.

Noordam R, Huurman NC, Wijsman CA, Akintola AA, Jansen SWM, Stassen S, Beekman M, van de Rest O, Slagboom PE, Mooijaart SP, van Heemst D.

Front Endocrinol (Lausanne). 2018 May 14;9:238. doi: 10.3389/fendo.2018.00238. eCollection 2018.

20.

Functional and cognitive impairment, social functioning, frailty and adverse health outcomes in older patients with esophageal cancer, a systematic review.

van Deudekom FJ, Klop HG, Hartgrink HH, Boonstra JJ, Lips IM, Slingerland M, Mooijaart SP.

J Geriatr Oncol. 2018 Nov;9(6):560-568. doi: 10.1016/j.jgo.2018.03.019. Epub 2018 Apr 19.

21.

Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study.

O Riordan D, Aubert CE, Walsh KA, Van Dorland A, Rodondi N, Du Puy RS, Poortvliet RKE, Gussekloo J, Sinnott C, Byrne S, Galvin R, Jukema JW, Mooijaart SP, Baumgartner C, McCarthy V, Walsh EK, Collet TH, Dekkers OM, Blum MR, Kearney PM.

BMJ Open. 2018 Mar 22;8(3):e019003. doi: 10.1136/bmjopen-2017-019003.

22.

Statement on Minimum Standards for the Care of Older People in Emergency Departments by the Geriatric Emergency Medicine Special Interest Group of the International Federation for Emergency Medicine - ERRATUM.

Ellis B, Carpenter CR, Lowthian JA, Mooijaart SP, Nickel CH, Melady D.

CJEM. 2019 Sep;21(5):E7. doi: 10.1017/cem.2018.39. No abstract available.

PMID:
29547361
23.

Predictors and Outcomes of Revisits in Older Adults Discharged from the Emergency Department.

de Gelder J, Lucke JA, de Groot B, Fogteloo AJ, Anten S, Heringhaus C, Dekkers OM, Blauw GJ, Mooijaart SP.

J Am Geriatr Soc. 2018 Apr;66(4):735-741. doi: 10.1111/jgs.15301. Epub 2018 Feb 28.

PMID:
29489015
24.

Regression discontinuity was a valid design for dichotomous outcomes in three randomized trials.

van Leeuwen N, Lingsma HF, Mooijaart SP, Nieboer D, Trompet S, Steyerberg EW.

J Clin Epidemiol. 2018 Jun;98:70-79. doi: 10.1016/j.jclinepi.2018.02.015. Epub 2018 Feb 24.

PMID:
29486280
25.

Determinants of self-rated health in older adults before and 3 months after an emergency department visit: a prospective study.

Van Deudekom FJ, De Gelder J, Lucke JA, Oostendorp-Lange A, Anten S, Blauw GJ, De Groot B, Mooijaart SP.

Eur J Emerg Med. 2019 Aug;26(4):255-260. doi: 10.1097/MEJ.0000000000000538.

PMID:
29384753
26.

Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997.

Delles C, Rankin NJ, Boachie C, McConnachie A, Ford I, Kangas A, Soininen P, Trompet S, Mooijaart SP, Jukema JW, Zannad F, Ala-Korpela M, Salomaa V, Havulinna AS, Welsh P, Würtz P, Sattar N.

Eur J Heart Fail. 2018 Apr;20(4):663-673. doi: 10.1002/ejhf.1076. Epub 2017 Dec 11.

27.

Optimising the ISAR-HP to screen efficiently for functional decline in older patients.

de Gelder J, Haenen E, Lucke JA, Klop HG, Blomaard LC, Smit RAJ, Mesri K, de Groot B, Fogteloo AJ, Anten S, Blauw GJ, Mooijaart SP.

Neth J Med. 2017 Nov;75(9):379-385.

28.

Association of complement receptor 1 gene polymorphisms with cognitive function.

Zijlstra LE, Jukema JW, Mooijaart SP, de Vries MA, Stott DJ, Castro Cabezas M, Trompet S.

Physiol Genomics. 2018 Feb 1;50(2):102-103. doi: 10.1152/physiolgenomics.00102.2017. Epub 2017 Dec 8.

29.

Association of diastolic blood pressure with cardiovascular events in older people varies upon cardiovascular history.

Wijsman LW, Muller M, de Craen AJM, Jukema JW, Westendorp RGJ, Mooijaart SP.

J Hypertens. 2018 Apr;36(4):773-778. doi: 10.1097/HJH.0000000000001625.

PMID:
29189468
30.

Impaired cognition is associated with adverse outcome in older patients in the Emergency Department; the Acutely Presenting Older Patients (APOP) study.

Lucke JA, de Gelder J, Heringhaus C, van der Mast RC, Fogteloo AJ, Anten S, Blauw GJ, de Groot B, Mooijaart SP.

Age Ageing. 2018 Sep 1;47(5):679-684. doi: 10.1093/ageing/afx174.

PMID:
29177470
31.

High Liver Enzyme Concentrations are Associated with Higher Glycemia, but not with Glycemic Variability, in Individuals without Diabetes Mellitus.

Noordam R, Vermond D, Drenth H, Wijman CA, Akintola AA, van der Kroef S, Jansen SWM, Huurman NC, Schutte BAM, Beekman M, Slagboom PE, Mooijaart SP, van Heemst D.

Front Endocrinol (Lausanne). 2017 Sep 13;8:236. doi: 10.3389/fendo.2017.00236. eCollection 2017.

32.

The most commonly used disease severity scores are inappropriate for risk stratification of older emergency department sepsis patients: an observational multi-centre study.

de Groot B, Stolwijk F, Warmerdam M, Lucke JA, Singh GK, Abbas M, Mooijaart SP, Ansems A, Esteve Cuevas L, Rijpsma D.

Scand J Trauma Resusc Emerg Med. 2017 Sep 11;25(1):91. doi: 10.1186/s13049-017-0436-3.

33.

Early prediction of hospital admission for emergency department patients: a comparison between patients younger or older than 70 years.

Lucke JA, de Gelder J, Clarijs F, Heringhaus C, de Craen AJM, Fogteloo AJ, Blauw GJ, Groot B, Mooijaart SP.

Emerg Med J. 2018 Jan;35(1):18-27. doi: 10.1136/emermed-2016-205846. Epub 2017 Aug 16.

PMID:
28814479
34.

High-Sensitivity Cardiac Troponin Concentration and Risk of First-Ever Cardiovascular Outcomes in 154,052 Participants.

Willeit P, Welsh P, Evans JDW, Tschiderer L, Boachie C, Jukema JW, Ford I, Trompet S, Stott DJ, Kearney PM, Mooijaart SP, Kiechl S, Di Angelantonio E, Sattar N.

J Am Coll Cardiol. 2017 Aug 1;70(5):558-568. doi: 10.1016/j.jacc.2017.05.062. Review.

35.

Regret about the decision to start dialysis: a cross-sectional Dutch national survey.

Berkhout-Byrne N, Gaasbeek A, Mallat MJK, Rabelink TJ, Mooijaart SP, Dekker FW, van Buren M.

Neth J Med. 2017 Jul;75(6):225-234.

36.

Correction: The complex genetics of gait speed: genome-wide meta-analysis approach.

Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SLR, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G.

Aging (Albany NY). 2017 Jul;9(7):1844-1846. doi: 10.18632/aging.101260. Epub 2017 Jul 7. No abstract available.

37.

The Cognitive decline in Older Patients with End stage renal disease (COPE) study - rationale and design.

Berkhout-Byrne N, Kallenberg MH, Gaasbeek A, Rabelink TJ, Hammer S, van Buchem MA, van Osch MJ, Kroft LJM, Boom H, Mooijaart SP, van Buren M.

Curr Med Res Opin. 2017 Nov;33(11):2057-2064. doi: 10.1080/03007995.2017.1341404. Epub 2017 Jul 11.

PMID:
28604116
38.

Cognitive Testing in People at Increased Risk of Dementia Using a Smartphone App: The iVitality Proof-of-Principle Study.

Jongstra S, Wijsman LW, Cachucho R, Hoevenaar-Blom MP, Mooijaart SP, Richard E.

JMIR Mhealth Uhealth. 2017 May 25;5(5):e68. doi: 10.2196/mhealth.6939.

39.

Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.

Stott DJ, Rodondi N, Kearney PM, Ford I, Westendorp RGJ, Mooijaart SP, Sattar N, Aubert CE, Aujesky D, Bauer DC, Baumgartner C, Blum MR, Browne JP, Byrne S, Collet TH, Dekkers OM, den Elzen WPJ, Du Puy RS, Ellis G, Feller M, Floriani C, Hendry K, Hurley C, Jukema JW, Kean S, Kelly M, Krebs D, Langhorne P, McCarthy G, McCarthy V, McConnachie A, McDade M, Messow M, O'Flynn A, O'Riordan D, Poortvliet RKE, Quinn TJ, Russell A, Sinnott C, Smit JWA, Van Dorland HA, Walsh KA, Walsh EK, Watt T, Wilson R, Gussekloo J; TRUST Study Group.

N Engl J Med. 2017 Jun 29;376(26):2534-2544. doi: 10.1056/NEJMoa1603825. Epub 2017 Apr 3.

40.

External validity of randomized controlled trials in older adults, a systematic review.

van Deudekom FJ, Postmus I, van der Ham DJ, Pothof AB, Broekhuizen K, Blauw GJ, Mooijaart SP.

PLoS One. 2017 Mar 27;12(3):e0174053. doi: 10.1371/journal.pone.0174053. eCollection 2017. Review.

41.

Secondary phenotype analysis in ascertained family designs: application to the Leiden longevity study.

Tissier R, Tsonaka R, Mooijaart SP, Slagboom E, Houwing-Duistermaat JJ.

Stat Med. 2017 Jun 30;36(14):2288-2301. doi: 10.1002/sim.7281. Epub 2017 Mar 16.

42.

The complex genetics of gait speed: genome-wide meta-analysis approach.

Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SL, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G.

Aging (Albany NY). 2017 Jan 10;9(1):209-246. doi: 10.18632/aging.101151. Erratum in: Aging (Albany NY). 2017 Jul 7;9(7):1844-1846.

43.

Complement receptor 1 gene polymorphisms are associated with cardiovascular risk.

de Vries MA, Trompet S, Mooijaart SP, Smit RA, Böhringer S, Castro Cabezas M, Jukema JW.

Atherosclerosis. 2017 Feb;257:16-21. doi: 10.1016/j.atherosclerosis.2016.12.017. Epub 2016 Dec 20.

PMID:
28033544
44.

Functional and cognitive impairment, social environment, frailty and adverse health outcomes in older patients with head and neck cancer, a systematic review.

van Deudekom FJ, Schimberg AS, Kallenberg MH, Slingerland M, van der Velden LA, Mooijaart SP.

Oral Oncol. 2017 Jan;64:27-36. doi: 10.1016/j.oraloncology.2016.11.013. Epub 2016 Dec 1. Review.

45.

Predicting adverse health outcomes in older emergency department patients: the APOP study.

de Gelder J, Lucke JA, de Groot B, Fogteloo AJ, Anten S, Mesri K, Steyerberg EW, Heringhaus C, Blauw GJ, Mooijaart SP.

Neth J Med. 2016 Oct;74(8):342-352.

46.

Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies.

Rieben C, Segna D, da Costa BR, Collet TH, Chaker L, Aubert CE, Baumgartner C, Almeida OP, Hogervorst E, Trompet S, Masaki K, Mooijaart SP, Gussekloo J, Peeters RP, Bauer DC, Aujesky D, Rodondi N.

J Clin Endocrinol Metab. 2016 Dec;101(12):4945-4954. Epub 2016 Sep 30. Review.

47.

Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study.

Hofman SE, Lucke JA, Heim N, de Gelder J, Fogteloo AJ, Heringhaus C, de Groot B, de Craen AJ, Blauw GJ, Mooijaart SP.

BMC Emerg Med. 2016 Jul 13;16(1):26. doi: 10.1186/s12873-016-0090-5.

48.

Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity.

Deelen J, van den Akker EB, Trompet S, van Heemst D, Mooijaart SP, Slagboom PE, Beekman M.

Exp Gerontol. 2016 Sep;82:166-74. doi: 10.1016/j.exger.2016.06.013. Epub 2016 Jun 29.

49.

Functional and Cognitive Impairment, Frailty, and Adverse Health Outcomes in Older Patients Reaching ESRD-A Systematic Review.

Kallenberg MH, Kleinveld HA, Dekker FW, van Munster BC, Rabelink TJ, van Buren M, Mooijaart SP.

Clin J Am Soc Nephrol. 2016 Sep 7;11(9):1624-39. doi: 10.2215/CJN.13611215. Epub 2016 Jun 24. Review.

50.

The development, implementation and evaluation of a transitional care programme to improve outcomes of frail older patients after hospitalisation.

Heim N, Rolden H, van Fenema EM, Weverling-Rijnsburger AW, Tuijl JP, Jue P, Oleksik AM, de Craen AJ, Mooijaart SP, Blauw GJ, Westendorp RG, van der Mast RC, van Everdinck IE.

Age Ageing. 2016 Sep;45(5):643-51. doi: 10.1093/ageing/afw098. Epub 2016 Jun 13.

PMID:
27298381

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