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Items: 1 to 50 of 324

1.

Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo.

Boehm J, Davis R, Murar CE, Li T, McCleland B, Dong S, Yan H, Kerns J, Moody CJ, Wilson AJ, Graves AP, Mentzer M, Qi H, Yonchuk J, Kou JP, Foley J, Sanchez Y, Podolin PL, Bolognese B, Booth-Genthe C, Galop M, Wolfe L, Carr R, Callahan JF.

Bioorg Med Chem. 2018 Dec 21. pii: S0968-0896(18)31630-4. doi: 10.1016/j.bmc.2018.12.026. [Epub ahead of print]

PMID:
30626555
2.

Editorial overview: Viruses and cancer.

Moody C, Robertson E.

Curr Opin Virol. 2018 Oct;32:iv. doi: 10.1016/j.coviro.2018.11.003. No abstract available.

PMID:
30473419
3.

Impact of Replication Stress in Human Papillomavirus Pathogenesis.

Moody CA.

J Virol. 2019 Jan 4;93(2). pii: e01012-17. doi: 10.1128/JVI.01012-17. Print 2019 Jan 15. Review.

PMID:
30355682
4.

SETD2-dependent H3K36me3 plays a critical role in epigenetic regulation of the HPV31 life cycle.

Gautam D, Johnson BA, Mac M, Moody CA.

PLoS Pathog. 2018 Oct 12;14(10):e1007367. doi: 10.1371/journal.ppat.1007367. eCollection 2018 Oct.

5.

Correlates of rate heterogeneity in avian ecomorphological traits.

Chira AM, Cooney CR, Bright JA, Capp EJR, Hughes EC, Moody CJA, Nouri LO, Varley ZK, Thomas GH.

Ecol Lett. 2018 Oct;21(10):1505-1514. doi: 10.1111/ele.13131. Epub 2018 Aug 21.

6.

Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position.

Cousin D, Hummersone MG, Bradshaw TD, Zhang J, Moody CJ, Foreiter MB, Summers HS, Lewis W, Wheelhouse RT, Stevens MFG.

Medchemcomm. 2018 Jan 19;9(3):545-553. doi: 10.1039/c7md00554g. eCollection 2018 Mar 1.

PMID:
30108945
7.

Origin of the Thiopyrone CTP-431 "Unexpectedly" Isolated from the Marine Sponge Cacospongia mycofijiensis.

Przeslak AD, Inman M, Lewis W, Moody CJ.

J Org Chem. 2018 Sep 7;83(17):10595-10601. doi: 10.1021/acs.joc.8b01258. Epub 2018 Aug 2.

PMID:
30044092
8.

Air-Liquid Interface System To Understand Epstein-Barr Virus-Associated Nasopharyngeal Carcinoma.

Hopcraft SE, Moody CA, Damania B.

mSphere. 2018 Jul 18;3(4). pii: e00350-18. doi: 10.1128/mSphere.00350-18.

9.

Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase γ (PI3Kγ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS).

Come JH, Collier PN, Henderson JA, Pierce AC, Davies RJ, Le Tiran A, O'Dowd H, Bandarage UK, Cao J, Deininger D, Grey R, Krueger EB, Lowe DB, Liang J, Liao Y, Messersmith D, Nanthakumar S, Sizensky E, Wang J, Xu J, Chin EY, Damagnez V, Doran JD, Dworakowski W, Griffith JP, Jacobs MD, Khare-Pandit S, Mahajan S, Moody CS, Aronov AM.

J Med Chem. 2018 Jun 28;61(12):5245-5256. doi: 10.1021/acs.jmedchem.8b00085. Epub 2018 Jun 14.

PMID:
29847724
10.

Replenishable drug depot to combat post-resection cancer recurrence.

Brudno Y, Pezone MJ, Snyder TK, Uzun O, Moody CT, Aizenberg M, Mooney DJ.

Biomaterials. 2018 Sep;178:373-382. doi: 10.1016/j.biomaterials.2018.05.005. Epub 2018 May 6.

PMID:
29779862
11.

Contribution of parenting to complex syntax development in preschool children with developmental delays or typical development.

Moody CT, Baker BL, Blacher J.

J Intellect Disabil Res. 2018 Jul;62(7):604-616. doi: 10.1111/jir.12501. Epub 2018 May 10.

12.

Diastereoselective Synthesis of Highly Substituted, Amino- and Pyrrolidino-Tetrahydrofurans as Lead-Like Molecular Scaffolds.

Wales SM, Merisor EG, Adcock HV, Pearce CA, Strutt IR, Lewis W, Hamza D, Moody CJ.

Chemistry. 2018 Jun 7;24(32):8233-8239. doi: 10.1002/chem.201801046. Epub 2018 May 16.

PMID:
29656543
13.

Synthesis of Highly Substituted 1,2-Diazetidin-3-ones, Small-Ring Scaffolds for Drug Discovery.

Santos MS, Nortcliffe A, Lewis W, Bradshaw TD, Moody CJ.

Chemistry. 2018 Jun 12;24(33):8325-8330. doi: 10.1002/chem.201801309. Epub 2018 May 15.

PMID:
29604227
14.

Multisystem Analysis of Mycobacterium tuberculosis Reveals Kinase-Dependent Remodeling of the Pathogen-Environment Interface.

Carette X, Platig J, Young DC, Helmel M, Young AT, Wang Z, Potluri LP, Moody CS, Zeng J, Prisic S, Paulson JN, Muntel J, Madduri AVR, Velarde J, Mayfield JA, Locher C, Wang T, Quackenbush J, Rhee KY, Moody DB, Steen H, Husson RN.

MBio. 2018 Mar 6;9(2). pii: e02333-17. doi: 10.1128/mBio.02333-17.

15.

Cell-subtype-specific changes in adenosine pathways in schizophrenia.

O'Donovan SM, Sullivan C, Koene R, Devine E, Hasselfeld K, Moody CL, McCullumsmith RE.

Neuropsychopharmacology. 2018 Jul;43(8):1667-1674. doi: 10.1038/s41386-018-0028-6. Epub 2018 Feb 26.

PMID:
29483661
16.

Densely functionalised spirocyclic oxetane-piperidine scaffolds for drug discovery.

Geary GC, Nortcliffe A, Pearce CA, Hamza D, Jones G, Moody CJ.

Bioorg Med Chem. 2018 Feb 15;26(4):791-797. doi: 10.1016/j.bmc.2017.12.012. Epub 2017 Dec 8.

PMID:
29366687
17.

Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.

Wang T, Bemis G, Hanzelka B, Zuccola H, Wynn M, Moody CS, Green J, Locher C, Liu A, Gao H, Xu Y, Wang S, Wang J, Bennani YL, Thomson JA, Müh U.

ACS Med Chem Lett. 2017 Nov 28;8(12):1224-1229. doi: 10.1021/acsmedchemlett.7b00239. eCollection 2017 Dec 14.

18.

Corrigendum: Mega-evolutionary dynamics of the adaptive radiation of birds.

Cooney CR, Bright JA, Capp EJR, Chira AM, Hughes EC, Moody CJA, Nouri LO, Varley ZK, Thomas GH.

Nature. 2017 Dec 21;552(7685):430. doi: 10.1038/nature24665. Epub 2017 Nov 29.

19.

Mechanisms by which HPV Induces a Replication Competent Environment in Differentiating Keratinocytes.

Moody C.

Viruses. 2017 Sep 19;9(9). pii: E261. doi: 10.3390/v9090261. Review.

20.

Maximizing the Potential of Longitudinal Cohorts for Research in Neurodegenerative Diseases: A Community Perspective.

Moody CJ, Mitchell D, Kiser G, Aarsland D, Berg D, Brayne C, Costa A, Ikram MA, Mountain G, Rohrer JD, Teunissen CE, van den Berg LH, Wardlaw JM.

Front Neurosci. 2017 Aug 29;11:467. doi: 10.3389/fnins.2017.00467. eCollection 2017.

21.

Varied Reports of Adult Transgender Suicidality: Synthesizing and Describing the Peer-Reviewed and Gray Literature.

Adams N, Hitomi M, Moody C.

Transgend Health. 2017 Apr 1;2(1):60-75. doi: 10.1089/trgh.2016.0036. eCollection 2017. Review.

22.

C-H Insertion as a Key Step to Spiro-Oxetanes, Scaffolds for Drug Discovery.

Nicolle SM, Nortcliffe A, Bartrum HE, Lewis W, Hayes CJ, Moody CJ.

Chemistry. 2017 Oct 4;23(55):13623-13627. doi: 10.1002/chem.201703746. Epub 2017 Sep 5.

PMID:
28796404
23.

Organic matter properties of Fennoscandian ecosystems: Potential oxidation of northern environments under future change?

Clay GD, Worrall F, Plummer R, Moody CS.

Sci Total Environ. 2018 Jan 1;610-611:1496-1504. doi: 10.1016/j.scitotenv.2017.06.072. Epub 2017 Jun 22.

PMID:
28647153
24.

Total Synthesis of the Cyclic Dodecapeptides Wewakazole and Wewakazole B.

Inman M, Dexter HL, Moody CJ.

Org Lett. 2017 Jul 7;19(13):3454-3457. doi: 10.1021/acs.orglett.7b01393. Epub 2017 Jun 15.

PMID:
28617610
25.

Synthesis of 4-aminotetrahydropyran scaffolds for drug discovery.

Nortcliffe A, Milne GDS, Hamza D, Moody CJ.

Bioorg Med Chem. 2017 Apr 1;25(7):2218-2225. doi: 10.1016/j.bmc.2017.02.039. Epub 2017 Feb 24.

PMID:
28279558
26.

Thomas Laurence Moody.

Moody C.

BMJ. 2017 Feb 24;356:j904. doi: 10.1136/bmj.j904. No abstract available.

PMID:
28235794
27.

Mega-evolutionary dynamics of the adaptive radiation of birds.

Cooney CR, Bright JA, Capp EJR, Chira AM, Hughes EC, Moody CJA, Nouri LO, Varley ZK, Thomas GH.

Nature. 2017 Feb 16;542(7641):344-347. doi: 10.1038/nature21074. Epub 2017 Feb 1. Erratum in: Nature. 2017 Nov 29;:.

28.

Total Synthesis of the Post-translationally Modified Polyazole Peptide Antibiotic Goadsporin.

Dexter HL, Williams HE, Lewis W, Moody CJ.

Angew Chem Int Ed Engl. 2017 Mar 6;56(11):3069-3073. doi: 10.1002/anie.201612103. Epub 2017 Feb 1.

PMID:
28145618
29.

Peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) restores carbapenem susceptibility to NDM-1-positive pathogens in vitro and in vivo.

Sully EK, Geller BL, Li L, Moody CM, Bailey SM, Moore AL, Wong M, Nordmann P, Daly SM, Sturge CR, Greenberg DE.

J Antimicrob Chemother. 2017 Mar 1;72(3):782-790. doi: 10.1093/jac/dkw476.

30.

Early Initiation of Newborn Individualized Developmental Care and Assessment Program (NIDCAP) Reduces Length of Stay: A Quality Improvement Project.

Moody C, Callahan TJ, Aldrich H, Gance-Cleveland B, Sables-Baus S.

J Pediatr Nurs. 2017 Jan - Feb;32:59-63. doi: 10.1016/j.pedn.2016.11.001. Epub 2016 Dec 5.

PMID:
27923536
31.

Cost Savings Opportunities in Perioperative Management of the Patients With Orthopaedic Trauma.

Moody AE, Moody CE, Althausen PL.

J Orthop Trauma. 2016 Dec;30 Suppl 5:S7-S14.

PMID:
27870668
32.

Modulation of the DNA damage response during the life cycle of human papillomaviruses.

Anacker DC, Moody CA.

Virus Res. 2017 Mar 2;231:41-49. doi: 10.1016/j.virusres.2016.11.006. Epub 2016 Nov 9. Review.

33.

The Rb binding domain of HPV31 E7 is required to maintain high levels of DNA repair factors in infected cells.

Johnson BA, Aloor HL, Moody CA.

Virology. 2017 Jan;500:22-34. doi: 10.1016/j.virol.2016.09.029. Epub 2016 Oct 19.

34.

HPV31 utilizes the ATR-Chk1 pathway to maintain elevated RRM2 levels and a replication-competent environment in differentiating Keratinocytes.

Anacker DC, Aloor HL, Shepard CN, Lenzi GM, Johnson BA, Kim B, Moody CA.

Virology. 2016 Dec;499:383-396. doi: 10.1016/j.virol.2016.09.028. Epub 2016 Oct 17.

35.

A comparison of landfill leachates based on waste composition.

Moody CM, Townsend TG.

Waste Manag. 2017 May;63:267-274. doi: 10.1016/j.wasman.2016.09.020. Epub 2016 Oct 11.

PMID:
27742232
36.

Systematic review of statins in sepsis: There is no evidence of dose response.

Quinn M, Moody C, Tunnicliffe B, Khan Z, Manji M, Gudibande S, Murphy N, Whitehouse T, Snelson C, Veenith T.

Indian J Crit Care Med. 2016 Sep;20(9):534-41. doi: 10.4103/0972-5229.190366.

37.

Synthesis of the Reported Pyranonaphthoquinone Structure of the Indoleamine-2,3-dioxygenase Inhibitor Annulin B by Regioselective Diels-Alder Reaction.

Inman M, Carvalho C, Lewis W, Moody CJ.

J Org Chem. 2016 Sep 2;81(17):7924-30. doi: 10.1021/acs.joc.6b01622. Epub 2016 Aug 23.

PMID:
27513176
38.

Formal Total Synthesis of Diazonamide A by Indole Oxidative Rearrangement.

David N, Pasceri R, Kitson RR, Pradal A, Moody CJ.

Chemistry. 2016 Jul 25;22(31):10867-76. doi: 10.1002/chem.201601605. Epub 2016 Jun 27.

PMID:
27346186
39.

Re: "What Do We Know A bout the Association Between Firearm Legislation and Firearm-Related Injuries?".

Lott JR Jr, Moody CE, Whitley JE.

Am J Epidemiol. 2016 Jul 1;184(1):81-2. doi: 10.1093/aje/kww051. Epub 2016 Jun 16. No abstract available.

PMID:
27313216
40.

Impact of the DNA Damage Response on Human Papillomavirus Chromatin.

Gautam D, Moody CA.

PLoS Pathog. 2016 Jun 16;12(6):e1005613. doi: 10.1371/journal.ppat.1005613. eCollection 2016 Jun. Review. No abstract available.

41.

A Capacitance-Based Sensor for Hemodialysis Cannulation Training: A Proof-of-Concept Study.

Singapogu R, Jagannathan A, Nagarajan N, Moody C, Zhang G, Cull D.

Stud Health Technol Inform. 2016;220:379-82.

PMID:
27046609
42.

Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolines.

Patel A, Sharp SY, Hall K, Lewis W, Stevens MF, Workman P, Moody CJ.

Org Biomol Chem. 2016 Apr 28;14(16):3889-905. doi: 10.1039/c6ob00471g. Epub 2016 Apr 1.

PMID:
27035072
43.

Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N-H Insertion Reaction of Metallocarbenes with β-Aminoketone Derivatives.

Nicolle SM, Lewis W, Hayes CJ, Moody CJ.

Angew Chem Int Ed Engl. 2016 Mar 7;55(11):3749-53. doi: 10.1002/anie.201511433. Epub 2016 Feb 5.

PMID:
26847664
44.

Homologous Recombination Repair Factors Rad51 and BRCA1 Are Necessary for Productive Replication of Human Papillomavirus 31.

Chappell WH, Gautam D, Ok ST, Johnson BA, Anacker DC, Moody CA.

J Virol. 2015 Dec 23;90(5):2639-52. doi: 10.1128/JVI.02495-15.

45.

Total Synthesis of the Posttranslationally Modified Polyazole Peptide Antibiotic Plantazolicin A.

Wada H, Williams HE, Moody CJ.

Angew Chem Int Ed Engl. 2015 Dec 7;54(50):15147-51. doi: 10.1002/anie.201507062. Epub 2015 Oct 16.

PMID:
26473502
46.

A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity.

Xiong R, Zhou W, Siegel D, Kitson RR, Freed CR, Moody CJ, Ross D.

Mol Pharmacol. 2015 Dec;88(6):1045-54. doi: 10.1124/mol.115.101451. Epub 2015 Sep 24.

47.

Discovery of Highly Isoform Selective Thiazolopiperidine Inhibitors of Phosphoinositide 3-Kinase γ.

Collier PN, Messersmith D, Le Tiran A, Bandarage UK, Boucher C, Come J, Cottrell KM, Damagnez V, Doran JD, Griffith JP, Khare-Pandit S, Krueger EB, Ledeboer MW, Ledford B, Liao Y, Mahajan S, Moody CS, Roday S, Wang T, Xu J, Aronov AM.

J Med Chem. 2015 Jul 23;58(14):5684-8. doi: 10.1021/acs.jmedchem.5b00498. Epub 2015 Jul 6.

PMID:
26121481
48.

Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity.

Blunt CE, Torcuk C, Liu Y, Lewis W, Siegel D, Ross D, Moody CJ.

Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8740-5. doi: 10.1002/anie.201503323. Epub 2015 Jun 10.

PMID:
26096359
49.

Stereoselective Synthesis of Highly Substituted Tetrahydrofurans through Diverted Carbene O-H Insertion Reaction.

Nicolle SM, Lewis W, Hayes CJ, Moody CJ.

Angew Chem Int Ed Engl. 2015 Jul 13;54(29):8485-9. doi: 10.1002/anie.201502484. Epub 2015 Jun 9.

PMID:
26068952
50.

LMP1-Induced Sumoylation Influences the Maintenance of Epstein-Barr Virus Latency through KAP1.

Bentz GL, Moss CR 2nd, Whitehurst CB, Moody CA, Pagano JS.

J Virol. 2015 Aug;89(15):7465-77. doi: 10.1128/JVI.00711-15. Epub 2015 May 6.

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