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Items: 5


Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A2 and mediates its toxic activity.

Massimino ML, Simonato M, Spolaore B, Franchin C, Arrigoni G, Marin O, Monturiol-Gross L, Fernández J, Lomonte B, Tonello F.

Sci Rep. 2018 Jul 13;8(1):10619. doi: 10.1038/s41598-018-28846-4.


Bacterial Sphingomyelinases and Phospholipases as Virulence Factors.

Flores-Díaz M, Monturiol-Gross L, Naylor C, Alape-Girón A, Flieger A.

Microbiol Mol Biol Rev. 2016 Jun 15;80(3):597-628. doi: 10.1128/MMBR.00082-15. Print 2016 Sep. Review.


Clostridium perfringens phospholipase C induced ROS production and cytotoxicity require PKC, MEK1 and NFκB activation.

Monturiol-Gross L, Flores-Díaz M, Pineda-Padilla MJ, Castro-Castro AC, Alape-Giron A.

PLoS One. 2014 Jan 23;9(1):e86475. doi: 10.1371/journal.pone.0086475. eCollection 2014.


Internalization of Clostridium perfringens α-toxin leads to ERK activation and is involved on its cytotoxic effect.

Monturiol-Gross L, Flores-Díaz M, Campos-Rodríguez D, Mora R, Rodríguez-Vega M, Marks DL, Alape-Girón A.

Cell Microbiol. 2014 Apr;16(4):535-47. doi: 10.1111/cmi.12237. Epub 2013 Dec 13.


Reactive oxygen species and the MEK/ERK pathway are involved in the toxicity of clostridium perfringens α-toxin, a prototype bacterial phospholipase C.

Monturiol-Gross L, Flores-Díaz M, Araya-Castillo C, Pineda-Padilla MJ, Clark GC, Titball RW, Alape-Girón A.

J Infect Dis. 2012 Oct;206(8):1218-26. Epub 2012 Aug 16.


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