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Items: 18


A human-derived antibody targets misfolded SOD1 and ameliorates motor symptoms in mouse models of amyotrophic lateral sclerosis.

Maier M, Welt T, Wirth F, Montrasio F, Preisig D, McAfoose J, Vieira FG, Kulic L, Späni C, Stehle T, Perrin S, Weber M, Hock C, Nitsch RM, Grimm J.

Sci Transl Med. 2018 Dec 5;10(470). pii: eaah3924. doi: 10.1126/scitranslmed.aah3924.


Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.

Weihofen A, Liu Y, Arndt JW, Huy C, Quan C, Smith BA, Baeriswyl JL, Cavegn N, Senn L, Su L, Marsh G, Auluck PK, Montrasio F, Nitsch RM, Hirst WD, Cedarbaum JM, Pepinsky RB, Grimm J, Weinreb PH.

Neurobiol Dis. 2019 Apr;124:276-288. doi: 10.1016/j.nbd.2018.10.016. Epub 2018 Oct 28.


Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.

Nobuhara CK, DeVos SL, Commins C, Wegmann S, Moore BD, Roe AD, Costantino I, Frosch MP, Pitstick R, Carlson GA, Hock C, Nitsch RM, Montrasio F, Grimm J, Cheung AE, Dunah AW, Wittmann M, Bussiere T, Weinreb PH, Hyman BT, Takeda S.

Am J Pathol. 2017 Jun;187(6):1399-1412. doi: 10.1016/j.ajpath.2017.01.022. Epub 2017 Apr 11.


Paracrine diffusion of PrP(C) and propagation of prion infectivity by plasma membrane-derived microvesicles.

Mattei V, Barenco MG, Tasciotti V, Garofalo T, Longo A, Boller K, Löwer J, Misasi R, Montrasio F, Sorice M.

PLoS One. 2009;4(4):e5057. doi: 10.1371/journal.pone.0005057. Epub 2009 Apr 1.


Deletion of the amino-terminal domain of the prion protein does not impair prion protein-dependent neuronal differentiation and neuritogenesis.

Barenco MG, Valori CF, Roncoroni C, Loewer J, Montrasio F, Rossi D.

J Neurosci Res. 2009 Feb 15;87(3):806-19. doi: 10.1002/jnr.21894.


Lymphotoxin-beta receptor-dependent genes in lymph node and follicular dendritic cell transcriptomes.

Huber C, Thielen C, Seeger H, Schwarz P, Montrasio F, Wilson MR, Heinen E, Fu YX, Miele G, Aguzzi A.

J Immunol. 2005 May 1;174(9):5526-36.


Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP.

Nikles D, Bach P, Boller K, Merten CA, Montrasio F, Heppner FL, Aguzzi A, Cichutek K, Kalinke U, Buchholz CJ.

J Virol. 2005 Apr;79(7):4033-42.


Intrinsic resistance of oligodendrocytes to prion infection.

Prinz M, Montrasio F, Furukawa H, van der Haar ME, Schwarz P, Rülicke T, Giger OT, Häusler KG, Perez D, Glatzel M, Aguzzi A.

J Neurosci. 2004 Jun 30;24(26):5974-81.


Abnormal synaptic protein expression and cell death in murine scrapie.

Sisó S, Puig B, Varea R, Vidal E, Acín C, Prinz M, Montrasio F, Badiola J, Aguzzi A, Pumarola M, Ferrer I.

Acta Neuropathol. 2002 Jun;103(6):615-26. Epub 2002 Feb 26.


Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells.

Prinz M, Montrasio F, Klein MA, Schwarz P, Priller J, Odermatt B, Pfeffer K, Aguzzi A.

Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):919-24. Epub 2002 Jan 15.


Studies on prion replication in spleen.

Raeber AJ, Montrasio F, Hegyi I, Frigg R, Klein MA, Aguzzi A, Weissmann C.

Dev Immunol. 2001;8(3-4):291-304.


Interventional strategies against prion diseases.

Aguzzi A, Glatzel M, Montrasio F, Prinz M, Heppner FL.

Nat Rev Neurosci. 2001 Oct;2(10):745-9. Review.


Spongiform encephalopathies: insights from transgenic models.

Aguzzi A, Brandner S, Fischer MB, Furukawa H, Glatzel M, Hawkins C, Heppner FL, Montrasio F, Navarro B, Parizek P, Pekarik V, Prinz M, Raeber AJ, Röckl C, Klein MA.

Adv Virus Res. 2001;56:313-52. Review. No abstract available.


B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice.

Montrasio F, Cozzio A, Flechsig E, Rossi D, Klein MA, Rülicke T, Raeber AJ, Vosshenrich CA, Proft J, Aguzzi A, Weissmann C.

Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):4034-7. Epub 2001 Mar 13.


Prions and the lymphoreticular system.

Weissmann C, Raeber AJ, Montrasio F, Hegyi I, Frigg R, Klein MA, Aguzzi A.

Philos Trans R Soc Lond B Biol Sci. 2001 Feb 28;356(1406):177-84. Review.


Prions: health scare and biological challenge.

Aguzzi A, Montrasio F, Kaeser PS.

Nat Rev Mol Cell Biol. 2001 Feb;2(2):118-26. Review.


Prions: pathogenesis and reverse genetics.

Aguzzi A, Klein MA, Montrasio F, Pekarik V, Brandner S, Furukawa H, Käser P, Röckl C, Glatzel M.

Ann N Y Acad Sci. 2000;920:140-57. Review.


Impaired prion replication in spleens of mice lacking functional follicular dendritic cells.

Montrasio F, Frigg R, Glatzel M, Klein MA, Mackay F, Aguzzi A, Weissmann C.

Science. 2000 May 19;288(5469):1257-9.

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