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Items: 1 to 50 of 196

1.

A Consensus Binding Motif for the PP4 Protein Phosphatase.

Ueki Y, Kruse T, Weisser MB, Sundell GN, Larsen MSY, Mendez BL, Jenkins NP, Garvanska DH, Cressey L, Zhang G, Davey N, Montoya G, Ivarsson Y, Kettenbach AN, Nilsson J.

Mol Cell. 2019 Sep 25. pii: S1097-2765(19)30684-7. doi: 10.1016/j.molcel.2019.08.029. [Epub ahead of print]

PMID:
31585692
2.

Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites.

Lundby A, Franciosa G, Emdal KB, Refsgaard JC, Gnosa SP, Bekker-Jensen DB, Secher A, Maurya SR, Paul I, Mendez BL, Kelstrup CD, Francavilla C, Kveiborg M, Montoya G, Jensen LJ, Olsen JV.

Cell. 2019 Oct 3;179(2):543-560.e26. doi: 10.1016/j.cell.2019.09.008.

PMID:
31585087
3.

Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas.

Molina R, Stella S, Feng M, Sofos N, Jauniskis V, Pozdnyakova I, López-Méndez B, She Q, Montoya G.

Nat Commun. 2019 Sep 20;10(1):4302. doi: 10.1038/s41467-019-12244-z.

4.

Cementum protein 1-derived peptide (CEMP 1-p1) modulates hydroxyapatite crystal formation in vitro.

Montoya G, Correa R, Arenas J, Hoz L, Romo E, Arroyo R, Zeichner-David M, Arzate H.

J Pept Sci. 2019 Aug 13:e3211. doi: 10.1002/psc.3211. [Epub ahead of print]

PMID:
31410920
5.

Cost Effectiveness of Mirabegron Compared with Antimuscarinic Agents for the Treatment of Adults with Overactive Bladder in Colombia.

Parise H, Espinosa R, Dea K, Anaya P, Montoya G, Ng DB.

Pharmacoecon Open. 2019 Jun 5. doi: 10.1007/s41669-019-0149-9. [Epub ahead of print]

6.

High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage.

Slaymaker IM, Mesa P, Kellner MJ, Kannan S, Brignole E, Koob J, Feliciano PR, Stella S, Abudayyeh OO, Gootenberg JS, Strecker J, Montoya G, Zhang F.

Cell Rep. 2019 Mar 26;26(13):3741-3751.e5. doi: 10.1016/j.celrep.2019.02.094.

7.

Molecular architecture of the Jumonji C family histone demethylase KDM5B.

Dorosz J, Kristensen LH, Aduri NG, Mirza O, Lousen R, Bucciarelli S, Mehta V, Sellés-Baiget S, Solbak SMØ, Bach A, Mesa P, Hernandez PA, Montoya G, Nguyen TTTN, Rand KD, Boesen T, Gajhede M.

Sci Rep. 2019 Mar 11;9(1):4019. doi: 10.1038/s41598-019-40573-y.

8.

Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.

Stella S, Mesa P, Thomsen J, Paul B, Alcón P, Jensen SB, Saligram B, Moses ME, Hatzakis NS, Montoya G.

Cell. 2018 Dec 13;175(7):1856-1871.e21. doi: 10.1016/j.cell.2018.10.045. Epub 2018 Nov 29.

PMID:
30503205
9.

Recurring circadian disruption alters circadian clock sensitivity to resetting.

Leise TL, Goldberg A, Michael J, Montoya G, Solow S, Molyneux P, Vetrivelan R, Harrington ME.

Eur J Neurosci. 2018 Sep 30. doi: 10.1111/ejn.14179. [Epub ahead of print]

PMID:
30269396
10.

A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding.

Han W, Stella S, Zhang Y, Guo T, Sulek K, Peng-Lundgren L, Montoya G, She Q.

Nucleic Acids Res. 2018 Nov 2;46(19):10319-10330. doi: 10.1093/nar/gky844.

11.

Impacts of moisture content during ozonation of soils containing residual petroleum.

Chen T, Yavuz BM, Delgado AG, Montoya G, Winkle DV, Zuo Y, Kamath R, Westerhoff P, Krajmalnik-Brown R, Rittmann BE.

J Hazard Mater. 2018 Feb 15;344:1101-1108. doi: 10.1016/j.jhazmat.2017.11.060. Epub 2017 Dec 5.

PMID:
30216969
12.

Synthetic cementum protein 1-derived peptide regulates mineralization in vitro and promotes bone regeneration in vivo.

Correa R, Arenas J, Montoya G, Hoz L, López S, Salgado F, Arroyo R, Salmeron N, Romo E, Zeichner-David M, Arzate H.

FASEB J. 2019 Jan;33(1):1167-1178. doi: 10.1096/fj.201800434RR. Epub 2018 Aug 16.

PMID:
30113883
13.

Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.

Prieto J, Redondo P, López-Méndez B, D'Abramo M, Merino N, Blanco FJ, Duchateau P, Montoya G, Molina R.

Sci Rep. 2018 Jul 6;8(1):10286. doi: 10.1038/s41598-018-28599-0.

14.

Molecular basis of Tousled-Like Kinase 2 activation.

Mortuza GB, Hermida D, Pedersen AK, Segura-Bayona S, López-Méndez B, Redondo P, Rüther P, Pozdnyakova I, Garrote AM, Muñoz IG, Villamor-Payà M, Jauset C, Olsen JV, Stracker TH, Montoya G.

Nat Commun. 2018 Jun 28;9(1):2535. doi: 10.1038/s41467-018-04941-y.

15.

Pentacyclic Triterpenes from Cecropia telenitida Can Function as Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1.

Mosquera C, Panay AJ, Montoya G.

Molecules. 2018 Jun 14;23(6). pii: E1444. doi: 10.3390/molecules23061444.

16.

Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI.

Alba J, Marcaida MJ, Prieto J, Montoya G, Molina R, D'Abramo M.

J Comput Aided Mol Des. 2017 Dec;31(12):1063-1072. doi: 10.1007/s10822-017-0087-5. Epub 2017 Nov 25.

PMID:
29177929
17.

Class 2 CRISPR-Cas RNA-guided endonucleases: Swiss Army knives of genome editing.

Stella S, Alcón P, Montoya G.

Nat Struct Mol Biol. 2017 Nov;24(11):882-892. doi: 10.1038/nsmb.3486. Epub 2017 Oct 16. Review.

PMID:
29035385
18.

A novel TPR-BEN domain interaction mediates PICH-BEND3 association.

Pitchai GP, Kaulich M, Bizard AH, Mesa P, Yao Q, Sarlos K, Streicher WW, Nigg EA, Montoya G, Hickson ID.

Nucleic Acids Res. 2017 Nov 2;45(19):11413-11424. doi: 10.1093/nar/gkx792.

19.

Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail.

Han W, Pan S, López-Méndez B, Montoya G, She Q.

Nucleic Acids Res. 2017 Oct 13;45(18):10740-10750. doi: 10.1093/nar/gkx726.

20.

Synthetic Peptides Derived from Ribosomal Proteins of Leishmania spp. in Mucocutaneous Leishmaniasis: Diagnostic Usefulness.

Florez MM, de Oliveira CI, Puerta C, Guzman F, Ayala M, Montoya G, Delgado G.

Protein Pept Lett. 2017;24(10):982-988. doi: 10.2174/0929866524666170728143924.

PMID:
28758598
21.

[Artifex spondet peritiam artis (The artisan responds to his art)].

Montoya GJM.

Rev Colomb Psiquiatr. 2017 Jul - Sep;46(3):127-128. doi: 10.1016/j.rcp.2017.06.005. Spanish. No abstract available.

PMID:
28728795
22.

Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA.

Alcón P, Montoya G, Stella S.

Acta Crystallogr F Struct Biol Commun. 2017 Jul 1;73(Pt 7):409-415. doi: 10.1107/S2053230X1700838X. Epub 2017 Jun 20.

23.

Erratum: Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage.

Stella S, Alcón P, Montoya G.

Nature. 2017 Jul 27;547(7664):476. doi: 10.1038/nature23300. Epub 2017 Jul 5.

PMID:
28678773
24.

Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage.

Stella S, Alcón P, Montoya G.

Nature. 2017 Jun 22;546(7659):559-563. doi: 10.1038/nature22398. Epub 2017 May 31. Erratum in: Nature. 2017 Jul 27;547(7664):476.

PMID:
28562584
25.
26.

Electron Microscopy Structural Insights into CPAP Oligomeric Behavior: A Plausible Assembly Process of a Supramolecular Scaffold of the Centrosome.

Alvarez-Cabrera AL, Delgado S, Gil-Carton D, Mortuza GB, Montoya G, Sorzano CO, Tang TK, Carazo JM.

Front Mol Biosci. 2017 Mar 27;4:17. doi: 10.3389/fmolb.2017.00017. eCollection 2017.

27.

Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex.

Pitchai GP, Hickson ID, Streicher W, Montoya G, Mesa P.

Acta Crystallogr F Struct Biol Commun. 2016 Aug;72(Pt 8):646-51. doi: 10.1107/S2053230X16010724. Epub 2016 Jul 27.

28.

A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase.

Hertz EPT, Kruse T, Davey NE, López-Méndez B, Sigurðsson JO, Montoya G, Olsen JV, Nilsson J.

Mol Cell. 2016 Aug 18;63(4):686-695. doi: 10.1016/j.molcel.2016.06.024. Epub 2016 Jul 21.

29.

The genome editing revolution: A CRISPR-Cas TALE off-target story.

Stella S, Montoya G.

Bioessays. 2016 Jul;38 Suppl 1:S4-S13. doi: 10.1002/bies.201670903. Review.

PMID:
27417121
30.

Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions.

Prieto J, Redondo P, Merino N, Villate M, Montoya G, Blanco FJ, Molina R.

Acta Crystallogr F Struct Biol Commun. 2016 Jun;72(Pt 6):473-9. doi: 10.1107/S2053230X16007512. Epub 2016 May 23.

31.

Molecular architecture of the recombinant human MCM2-7 helicase in complex with nucleotides and DNA.

Boskovic J, Bragado-Nilsson E, Saligram Prabhakar B, Yefimenko I, Martínez-Gago J, Muñoz S, Méndez J, Montoya G.

Cell Cycle. 2016 Sep 16;15(18):2431-40. doi: 10.1080/15384101.2016.1191712. Epub 2016 Jun 1.

32.

Metabolite profiles of rats in repeated dose toxicological studies after oral and inhalative exposure.

Fabian E, Bordag N, Herold M, Kamp H, Krennrich G, Looser R, Ma-Hock L, Mellert W, Montoya G, Peter E, Prokudin A, Spitzer M, Strauss V, Walk T, Zbranek R, van Ravenzwaay B.

Toxicol Lett. 2016 Jul 25;255:11-23. doi: 10.1016/j.toxlet.2016.05.003. Epub 2016 May 3.

PMID:
27153797
33.

Key Players in I-DmoI Endonuclease Catalysis Revealed from Structure and Dynamics.

Molina R, Besker N, Marcaida MJ, Montoya G, Prieto J, D'Abramo M.

ACS Chem Biol. 2016 May 20;11(5):1401-7. doi: 10.1021/acschembio.5b00730. Epub 2016 Mar 8.

PMID:
26909878
34.

A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.

Starnes LM, Su D, Pikkupeura LM, Weinert BT, Santos MA, Mund A, Soria R, Cho YW, Pozdnyakova I, Kubec Højfeldt M, Vala A, Yang W, López-Méndez B, Lee JE, Peng W, Yuan J, Ge K, Montoya G, Nussenzweig A, Choudhary C, Daniel JA.

Genes Dev. 2016 Jan 15;30(2):149-63. doi: 10.1101/gad.268797.115. Epub 2016 Jan 7.

35.

Genetic contributions to circadian activity rhythm and sleep pattern phenotypes in pedigrees segregating for severe bipolar disorder.

Pagani L, St Clair PA, Teshiba TM, Service SK, Fears SC, Araya C, Araya X, Bejarano J, Ramirez M, Castrillón G, Gomez-Makhinson J, Lopez MC, Montoya G, Montoya CP, Aldana I, Navarro L, Freimer DG, Safaie B, Keung LW, Greenspan K, Chou K, Escobar JI, Ospina-Duque J, Kremeyer B, Ruiz-Linares A, Cantor RM, Lopez-Jaramillo C, Macaya G, Molina J, Reus VI, Sabatti C, Bearden CE, Takahashi JS, Freimer NB.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):E754-61. doi: 10.1073/pnas.1513525113. Epub 2015 Dec 28.

36.

TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.

Hoffmann S, Smedegaard S, Nakamura K, Mortuza GB, Räschle M, Ibañez de Opakua A, Oka Y, Feng Y, Blanco FJ, Mann M, Montoya G, Groth A, Bekker-Jensen S, Mailand N.

J Cell Biol. 2016 Jan 4;212(1):63-75. doi: 10.1083/jcb.201506071. Epub 2015 Dec 28.

37.

Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification.

Molina R, Redondo P, López-Méndez B, Villate M, Merino N, Blanco FJ, Valton J, Grizot S, Duchateau P, Prieto J, Montoya G.

J Biol Chem. 2015 Nov 27;290(48):28727-36. doi: 10.1074/jbc.M115.678342. Epub 2015 Sep 11.

38.

Functional and in silico assessment of MAX variants of unknown significance.

Comino-Méndez I, Leandro-García LJ, Montoya G, Inglada-Pérez L, de Cubas AA, Currás-Freixes M, Tysoe C, Izatt L, Letón R, Gómez-Graña Á, Mancikova V, Apellániz-Ruiz M, Mannelli M, Schiavi F, Favier J, Gimenez-Roqueplo AP, Timmers HJ, Roncador G, Garcia JF, Rodríguez-Antona C, Robledo M, Cascón A.

J Mol Med (Berl). 2015 Nov;93(11):1247-55. doi: 10.1007/s00109-015-1306-y. Epub 2015 Jun 14.

PMID:
26070438
39.

Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold.

Molina R, Marcaida MJ, Redondo P, Marenchino M, Duchateau P, D'Abramo M, Montoya G, Prieto J.

J Biol Chem. 2015 Jul 24;290(30):18534-44. doi: 10.1074/jbc.M115.658666. Epub 2015 Jun 4.

40.

Structure of p15(PAF)-PCNA complex and implications for clamp sliding during DNA replication and repair.

De Biasio A, de Opakua AI, Mortuza GB, Molina R, Cordeiro TN, Castillo F, Villate M, Merino N, Delgado S, Gil-Cartón D, Luque I, Diercks T, Bernadó P, Montoya G, Blanco FJ.

Nat Commun. 2015 Mar 12;6:6439. doi: 10.1038/ncomms7439.

PMID:
25762514
41.

Visualizing phosphodiester-bond hydrolysis by an endonuclease.

Molina R, Stella S, Redondo P, Gomez H, Marcaida MJ, Orozco M, Prieto J, Montoya G.

Nat Struct Mol Biol. 2015 Jan;22(1):65-72. doi: 10.1038/nsmb.2932. Epub 2014 Dec 8.

PMID:
25486305
42.

Human recombinant cementum attachment protein (hrPTPLa/CAP) promotes hydroxyapatite crystal formation in vitro and bone healing in vivo.

Montoya G, Arenas J, Romo E, Zeichner-David M, Alvarez M, Narayanan AS, Velázquez U, Mercado G, Arzate H.

Bone. 2014 Dec;69:154-64. doi: 10.1016/j.bone.2014.09.014. Epub 2014 Sep 28.

PMID:
25263524
43.

XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation.

Mortuza GB, Cavazza T, Garcia-Mayoral MF, Hermida D, Peset I, Pedrero JG, Merino N, Blanco FJ, Lyngsø J, Bruix M, Pedersen JS, Vernos I, Montoya G.

Nat Commun. 2014 Sep 29;5:5072. doi: 10.1038/ncomms6072.

44.

Modulation of 3',5'-cyclic AMP homeostasis in human platelets by coffee and individual coffee constituents.

Montoya GA, Bakuradze T, Eirich M, Erk T, Baum M, Habermeyer M, Eisenbrand G, Richling E.

Br J Nutr. 2014 Nov 14;112(9):1427-37. doi: 10.1017/S0007114514002232. Epub 2014 Sep 23.

PMID:
25247601
45.

Quantitation of trans-aconitic acid in different stages of the sugar-manufacturing process.

Montoya G, Londono J, Cortes P, Izquierdo O.

J Agric Food Chem. 2014 Aug 20;62(33):8314-8. doi: 10.1021/jf5008874. Epub 2014 Aug 11.

PMID:
25098840
46.

BuD, a helix-loop-helix DNA-binding domain for genome modification.

Stella S, Molina R, López-Méndez B, Juillerat A, Bertonati C, Daboussi F, Campos-Olivas R, Duchateau P, Montoya G.

Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):2042-52. doi: 10.1107/S1399004714011183. Epub 2014 Jun 29.

47.

The C-terminal SH3 domain contributes to the intramolecular inhibition of Vav family proteins.

Barreira M, Fabbiano S, Couceiro JR, Torreira E, Martínez-Torrecuadrada JL, Montoya G, Llorca O, Bustelo XR.

Sci Signal. 2014 Apr 15;7(321):ra35. doi: 10.1126/scisignal.2004993.

PMID:
24736456
48.

The sensitivity of metabolomics versus classical regulatory toxicology from a NOAEL perspective.

van Ravenzwaay B, Montoya GA, Fabian E, Herold M, Krennrich G, Looser R, Mellert W, Peter E, Strauss V, Walk T, Kamp H.

Toxicol Lett. 2014 May 16;227(1):20-8. doi: 10.1016/j.toxlet.2014.03.004. Epub 2014 Mar 19.

PMID:
24657160
49.

Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA.

Redondo P, Merino N, Villate M, Blanco FJ, Montoya G, Molina R.

Acta Crystallogr F Struct Biol Commun. 2014 Feb;70(Pt 2):256-9. doi: 10.1107/S2053230X1400065X. Epub 2014 Jan 22.

50.

Purification, crystallization and preliminary X-ray diffraction analysis of the kinase domain of human tousled-like kinase 2.

Garrote AM, Redondo P, Montoya G, Muñoz IG.

Acta Crystallogr F Struct Biol Commun. 2014 Mar;70(Pt 3):354-7. doi: 10.1107/S2053230X14002581. Epub 2014 Feb 19.

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