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Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.

Shinsky SA, Monteith KE, Viggiano S, Cosgrove MS.

J Biol Chem. 2015 Mar 6;290(10):6361-75. doi: 10.1074/jbc.M114.627646. Epub 2015 Jan 5.


Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing.

Tie F, Banerjee R, Saiakhova AR, Howard B, Monteith KE, Scacheri PC, Cosgrove MS, Harte PJ.

Development. 2014 Mar;141(5):1129-39. doi: 10.1242/dev.102392.


Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.

Patel A, Vought VE, Swatkoski S, Viggiano S, Howard B, Dharmarajan V, Monteith KE, Kupakuwana G, Namitz KE, Shinsky SA, Cotter RJ, Cosgrove MS.

J Biol Chem. 2014 Jan 10;289(2):868-84. doi: 10.1074/jbc.M113.501064. Epub 2013 Nov 14.

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