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Items: 48

1.

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.

Fagan V, Johansson C, Gileadi C, Monteiro O, Dunford JE, Nibhani R, Philpott M, Malzahn J, Wells G, Faram R, Cribbs AP, Halidi N, Li F, Chau I, Greschik H, Velupillai S, Allali-Hassani A, Bennett J, Christott T, Giroud C, Lewis AM, Huber KVM, Athanasou N, Bountra C, Jung M, Schüle R, Vedadi M, Arrowsmith C, Xiong Y, Jin J, Fedorov O, Farnie G, Brennan PE, Oppermann U.

J Med Chem. 2019 Oct 24;62(20):9008-9025. doi: 10.1021/acs.jmedchem.9b00562. Epub 2019 Oct 15.

PMID:
31550156
2.

Tuning Surface Chemoresistivity of Au Ultrathin Films Using Metal Deposition via Surface-Limited Redox Replacement of the Underpotentially Deposited Pb Monolayer.

Ahmadi K, Wu D, Dole N, Monteiro OR, Brankovic SR.

ACS Sens. 2019 Sep 27;4(9):2442-2449. doi: 10.1021/acssensors.9b01045. Epub 2019 Sep 5.

PMID:
31441296
3.

Degradation of duloxetine: Identification of transformation products by UHPLC-ESI(+)-HRMS/MS, in silico toxicity and wastewater analysis.

Osawa RA, Carvalho AP, Monteiro OC, Oliveira MC, Florêncio MH.

J Environ Sci (China). 2019 Aug;82:113-123. doi: 10.1016/j.jes.2019.02.025. Epub 2019 Mar 7.

PMID:
31133256
4.

An Activity-Based Probe Targeting Non-Catalytic, Highly Conserved Amino Acid Residues within Bromodomains.

D'Ascenzio M, Pugh KM, Konietzny R, Berridge G, Tallant C, Hashem S, Monteiro O, Thomas JR, Schirle M, Knapp S, Marsden B, Fedorov O, Bountra C, Kessler BM, Brennan PE.

Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1007-1012. doi: 10.1002/anie.201807825. Epub 2018 Dec 27.

5.

Transformation products of citalopram: Identification, wastewater analysis and in silico toxicological assessment.

Osawa RA, Carvalho AP, Monteiro OC, Oliveira MC, Florêncio MH.

Chemosphere. 2019 Feb;217:858-868. doi: 10.1016/j.chemosphere.2018.11.027. Epub 2018 Nov 5.

PMID:
30458421
6.

Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9.

Christott T, Bennett J, Coxon C, Monteiro O, Giroud C, Beke V, Felce SL, Gamble V, Gileadi C, Poda G, Al-Awar R, Farnie G, Fedorov O.

SLAS Discov. 2019 Feb;24(2):133-141. doi: 10.1177/2472555218809904. Epub 2018 Oct 25.

PMID:
30359161
7.

Discovery of an MLLT1/3 YEATS Domain Chemical Probe.

Moustakim M, Christott T, Monteiro OP, Bennett J, Giroud C, Ward J, Rogers CM, Smith P, Panagakou I, Díaz-Sáez L, Felce SL, Gamble V, Gileadi C, Halidi N, Heidenreich D, Chaikuad A, Knapp S, Huber KVM, Farnie G, Heer J, Manevski N, Poda G, Al-Awar R, Dixon DJ, Brennan PE, Fedorov O.

Angew Chem Int Ed Engl. 2018 Dec 10;57(50):16302-16307. doi: 10.1002/anie.201810617. Epub 2018 Nov 16.

8.

Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease.

Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert JJ, Wanker E, Methner A, Krauss S, Schweiger S, Stroh A.

Elife. 2018 Sep 4;7. pii: e38744. doi: 10.7554/eLife.38744.

9.

Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2.

Moustakim M, Riedel K, Schuller M, Gehring AP, Monteiro OP, Martin SP, Fedorov O, Heer J, Dixon DJ, Elkins JM, Knapp S, Bracher F, Brennan PE.

Bioorg Med Chem. 2018 Jul 15;26(11):2965-2972. doi: 10.1016/j.bmc.2018.03.020. Epub 2018 Mar 12.

10.

Pharmacological disruption of the MID1/α4 interaction reduces mutant Huntingtin levels in primary neuronal cultures.

Monteiro O, Chen C, Bingham R, Argyrou A, Buxton R, Pancevac Jönsson C, Jones E, Bridges A, Gatfield K, Krauß S, Lambert J, Langston R, Schweiger S, Uings I.

Neurosci Lett. 2018 Apr 23;673:44-50. doi: 10.1016/j.neulet.2018.02.061. Epub 2018 Feb 27.

PMID:
29499308
11.

Selective inhibition of extra-synaptic α5-GABAA receptors by S44819, a new therapeutic agent.

Etherington LA, Mihalik B, Pálvölgyi A, Ling I, Pallagi K, Kertész S, Varga P, Gunn BG, Brown AR, Livesey MR, Monteiro O, Belelli D, Barkóczy J, Spedding M, Gacsályi I, Antoni FA, Lambert JJ.

Neuropharmacology. 2017 Oct;125:353-364. doi: 10.1016/j.neuropharm.2017.08.012. Epub 2017 Aug 12.

PMID:
28807671
12.

Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.

Bouché L, Christ CD, Siegel S, Fernández-Montalván AE, Holton SJ, Fedorov O, Ter Laak A, Sugawara T, Stöckigt D, Tallant C, Bennett J, Monteiro O, Díaz-Sáez L, Siejka P, Meier J, Pütter V, Weiske J, Müller S, Huber KVM, Hartung IV, Haendler B.

J Med Chem. 2017 May 11;60(9):4002-4022. doi: 10.1021/acs.jmedchem.7b00306. Epub 2017 May 1.

13.

Chemical composition and acaricide activity of an essential oil from a rare chemotype of Cinnamomum verum Presl on Rhipicephalus microplus (Acari: Ixodidae).

Monteiro IN, Monteiro ODS, Costa-Junior LM, da Silva Lima A, Andrade EHA, Maia JGS, Mouchrek Filho VE.

Vet Parasitol. 2017 Apr 30;238:54-57. doi: 10.1016/j.vetpar.2017.03.016. Epub 2017 Mar 18.

14.

Discovery of a PCAF Bromodomain Chemical Probe.

Moustakim M, Clark PG, Trulli L, Fuentes de Arriba AL, Ehebauer MT, Chaikuad A, Murphy EJ, Mendez-Johnson J, Daniels D, Hou CD, Lin YH, Walker JR, Hui R, Yang H, Dorrell L, Rogers CM, Monteiro OP, Fedorov O, Huber KV, Knapp S, Heer J, Dixon DJ, Brennan PE.

Angew Chem Int Ed Engl. 2017 Jan 16;56(3):827-831. doi: 10.1002/anie.201610816. Epub 2016 Dec 14.

15.

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.

Picaud S, Leonards K, Lambert JP, Dovey O, Wells C, Fedorov O, Monteiro O, Fujisawa T, Wang CY, Lingard H, Tallant C, Nikbin N, Guetzoyan L, Ingham R, Ley SV, Brennan P, Muller S, Samsonova A, Gingras AC, Schwaller J, Vassiliou G, Knapp S, Filippakopoulos P.

Sci Adv. 2016 Oct 12;2(10):e1600760. eCollection 2016 Oct.

16.

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.

Clark PG, Vieira LC, Tallant C, Fedorov O, Singleton DC, Rogers CM, Monteiro OP, Bennett JM, Baronio R, Müller S, Daniels DL, Méndez J, Knapp S, Brennan PE, Dixon DJ.

Angew Chem Weinheim Bergstr Ger. 2015 May 18;127(21):6315-6319. Epub 2015 Apr 13.

17.

The effect of ionic Co presence on the structural, optical and photocatalytic properties of modified cobalt-titanate nanotubes.

Barrocas B, Silvestre AJ, Rolo AG, Monteiro OC.

Phys Chem Chem Phys. 2016 Jul 21;18(27):18081-93. doi: 10.1039/c6cp01889k. Epub 2016 Jun 21.

PMID:
27327644
18.

BET inhibition as a new strategy for the treatment of gastric cancer.

Montenegro RC, Clark PG, Howarth A, Wan X, Ceroni A, Siejka P, Nunez-Alonso GA, Monteiro O, Rogers C, Gamble V, Burbano R, Brennan PE, Tallant C, Ebner D, Fedorov O, O'Neill E, Knapp S, Dixon D, Müller S.

Oncotarget. 2016 Jul 12;7(28):43997-44012. doi: 10.18632/oncotarget.9766.

19.

Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex.

Sutherell CL, Tallant C, Monteiro OP, Yapp C, Fuchs JE, Fedorov O, Siejka P, Müller S, Knapp S, Brenton JD, Brennan PE, Ley SV.

J Med Chem. 2016 May 26;59(10):5095-101. doi: 10.1021/acs.jmedchem.5b01997. Epub 2016 May 11.

20.

A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain.

Cox OB, Krojer T, Collins P, Monteiro O, Talon R, Bradley A, Fedorov O, Amin J, Marsden BD, Spencer J, von Delft F, Brennan PE.

Chem Sci. 2016 Mar 1;7(3):2322-2330. doi: 10.1039/c5sc03115j. Epub 2015 Dec 22.

21.

Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.

Fedorov O, Castex J, Tallant C, Owen DR, Martin S, Aldeghi M, Monteiro O, Filippakopoulos P, Picaud S, Trzupek JD, Gerstenberger BS, Bountra C, Willmann D, Wells C, Philpott M, Rogers C, Biggin PC, Brennan PE, Bunnage ME, Schüle R, Günther T, Knapp S, Müller S.

Sci Adv. 2015 Nov 13;1(10):e1500723. doi: 10.1126/sciadv.1500723. eCollection 2015 Nov.

22.

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.

Picaud S, Fedorov O, Thanasopoulou A, Leonards K, Jones K, Meier J, Olzscha H, Monteiro O, Martin S, Philpott M, Tumber A, Filippakopoulos P, Yapp C, Wells C, Che KH, Bannister A, Robson S, Kumar U, Parr N, Lee K, Lugo D, Jeffrey P, Taylor S, Vecellio ML, Bountra C, Brennan PE, O'Mahony A, Velichko S, Müller S, Hay D, Daniels DL, Urh M, La Thangue NB, Kouzarides T, Prinjha R, Schwaller J, Knapp S.

Cancer Res. 2015 Dec 1;75(23):5106-5119. doi: 10.1158/0008-5472.CAN-15-0236. Epub 2015 Nov 9.

23.

Biotechnologically obtained nanocomposites: A practical application for photodegradation of Safranin-T under UV-Vis and solar light.

Pinto da Costa J, Girão AV, Monteiro OC, Trindade T, Costa MC.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2015;50(10):996-1010. doi: 10.1080/10934529.2015.1038155.

PMID:
26121015
24.

Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.

Bennett J, Fedorov O, Tallant C, Monteiro O, Meier J, Gamble V, Savitsky P, Nunez-Alonso GA, Haendler B, Rogers C, Brennan PE, Müller S, Knapp S.

J Med Chem. 2016 Feb 25;59(4):1642-7. doi: 10.1021/acs.jmedchem.5b00458. Epub 2015 May 20.

25.

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.

Clark PG, Vieira LC, Tallant C, Fedorov O, Singleton DC, Rogers CM, Monteiro OP, Bennett JM, Baronio R, Müller S, Daniels DL, Méndez J, Knapp S, Brennan PE, Dixon DJ.

Angew Chem Int Ed Engl. 2015 May 18;54(21):6217-21. doi: 10.1002/anie.201501394. Epub 2015 Apr 13.

26.

Structure enabled design of BAZ2-ICR, a chemical probe targeting the bromodomains of BAZ2A and BAZ2B.

Drouin L, McGrath S, Vidler LR, Chaikuad A, Monteiro O, Tallant C, Philpott M, Rogers C, Fedorov O, Liu M, Akhtar W, Hayes A, Raynaud F, Müller S, Knapp S, Hoelder S.

J Med Chem. 2015 Mar 12;58(5):2553-9. doi: 10.1021/jm501963e. Epub 2015 Feb 26.

27.

Vildagliptin induces β-cell neogenesis and improves the lipid profile in a later phase of type 1 diabetes.

de Amorim Miranda PH, Monteiro OM, Rossoni JV Jr, Silva ME, de Lima WG, Costa DC.

Curr Pharm Biotechnol. 2015;16(1):60-5.

PMID:
25395211
28.

Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains.

Hay DA, Fedorov O, Martin S, Singleton DC, Tallant C, Wells C, Picaud S, Philpott M, Monteiro OP, Rogers CM, Conway SJ, Rooney TP, Tumber A, Yapp C, Filippakopoulos P, Bunnage ME, Müller S, Knapp S, Schofield CJ, Brennan PE.

J Am Chem Soc. 2014 Jul 2;136(26):9308-19. doi: 10.1021/ja412434f. Epub 2014 Jun 19.

29.

[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains.

Fedorov O, Lingard H, Wells C, Monteiro OP, Picaud S, Keates T, Yapp C, Philpott M, Martin SJ, Felletar I, Marsden BD, Filippakopoulos P, Müller S, Knapp S, Brennan PE.

J Med Chem. 2014 Jan 23;57(2):462-76. doi: 10.1021/jm401568s. Epub 2013 Dec 30.

30.

Green synthesis of covellite nanocrystals using biologically generated sulfide: potential for bioremediation systems.

da Costa JP, Girão AV, Lourenço JP, Monteiro OC, Trindade T, Costa MC.

J Environ Manage. 2013 Oct 15;128:226-32. doi: 10.1016/j.jenvman.2013.05.034. Epub 2013 Jun 7.

PMID:
23747373
31.

Ferromagnetic order in aged Co-doped TiO2 anatase nanopowders.

Silvestre AJ, Pereira LC, Nunes MR, Monteiro OC.

J Nanosci Nanotechnol. 2012 Aug;12(8):6850-4.

PMID:
22962834
32.

Vesicle degradation in dendrites of magnocellular neurones of the rat supraoptic nucleus.

Monteiro O, Wiegand UK, Ludwig M.

Neurosci Lett. 2011 Feb 1;489(1):30-3. doi: 10.1016/j.neulet.2010.11.060. Epub 2010 Dec 1.

PMID:
21129440
33.

Radiographic study of patients submitted to total gastrectomy using Safatle reconstruction technique.

Meyer AL, Berger E, Monteiro O Jr, Alonso PA, Lerner JS.

Arq Gastroenterol. 2008 Jul-Sep;45(3):230-3.

34.

Photocatalytic decolorization of methylene blue in the presence of TiO2/ZnS nanocomposites.

Franco A, Neves MC, Carrott MM, Mendonça MH, Pereira MI, Monteiro OC.

J Hazard Mater. 2009 Jan 15;161(1):545-50. doi: 10.1016/j.jhazmat.2008.03.133. Epub 2008 Apr 6.

PMID:
18495340
35.

Quantitative and qualitative analysis of collagen types in the fascia transversalis of inguinal hernia patients.

Meyer AL, Berger E, Monteiro O Jr, Alonso PA, Stavale JN, Gonçalves MP.

Arq Gastroenterol. 2007 Jul-Sep;44(3):230-4.

36.

Relationship between Cu and Zn extractable foliar contents and BCR sequential extraction in soil treated with organic amendments.

Pedra F, Domingues H, Ribeiro AB, Polo A, Monteiro O.

Environ Technol. 2006 Dec;27(12):1357-67.

PMID:
17285941
37.

Bonding in liquid carbon studied by time-resolved x-ray absorption spectroscopy.

Johnson SL, Heimann PA, MacPhee AG, Lindenberg AM, Monteiro OR, Chang Z, Lee RW, Falcone RW.

Phys Rev Lett. 2005 Feb 11;94(5):057407. Epub 2005 Feb 10.

PMID:
15783698
38.

The influence of chitosans with defined degrees of acetylation on the thermodynamic data for copper coordination.

Monteiro OA Jr, Airoldi C.

J Colloid Interface Sci. 2005 Feb 1;282(1):32-7.

PMID:
15576078
39.

Zinc sulfide nanocoating of silica submicron spheres using a single-source method.

Monteiro OC, Neves MC, Trindade T.

J Nanosci Nanotechnol. 2004 Jan-Feb;4(1-2):146-50.

PMID:
15112558
40.

Optical properties of the synthetic nanocomposites SiO2/CdS/poly(styrene-co-maleic anhydride) and SiO2/CdS/poly(styrene-co-maleimide).

Esteves AC, Monteiro OC, Barros-Timmons AM, Boemare C, Soares MJ, Monteiro T, Trindade T.

J Nanosci Nanotechnol. 2002 Apr;2(2):177-81.

PMID:
12908306
41.
42.

Vagotomy reduces obesity in MSG-treated rats.

Balbo SL, Mathias PC, Bonfleur ML, Alves HF, Siroti FJ, Monteiro OG, Ribeiro FB, Souza AC.

Res Commun Mol Pathol Pharmacol. 2000 Nov-Dec;108(5-6):291-6.

PMID:
11958282
43.

Some studies of crosslinking chitosan-glutaraldehyde interaction in a homogeneous system.

Monteiro OA Jr, Airoldi C.

Int J Biol Macromol. 1999 Nov;26(2-3):119-28.

PMID:
10517518
44.

Silicon nitride coating on titanium to enable titanium-ceramic bonding.

Wang RR, Welsch GE, Monteiro O.

J Biomed Mater Res. 1999 Aug;46(2):262-70.

PMID:
10380005
45.

Some Thermodynamic Data on Copper-Chitin and Copper-Chitosan Biopolymer Interactions.

Monteiro OA Jr, Airoldi C.

J Colloid Interface Sci. 1999 Apr 15;212(2):212-219.

PMID:
10092348
46.

Bioactive surface coatings for nanoscale instruments: effects on CNS neurons.

Ignatius MJ, Sawhney N, Gupta A, Thibadeau BM, Monteiro OR, Brown IG.

J Biomed Mater Res. 1998 May;40(2):264-74.

PMID:
9549621
47.

Measles control in Maputo, Mozambique, using a single dose of Schwarz vaccine at age 9 months.

Cutts FT, Monteiro O, Tabard P, Cliff J.

Bull World Health Organ. 1994;72(2):227-31.

48.

Experimental study of the absorption and elimination of astiban labelled with 124Sb.

de Azevedo JF, Gil FB, Barreira F, da Rocha RM, Monteiro OS.

An Inst Med Trop (Lisb). 1966 Jan-Jun;23(1):3-10. No abstract available.

PMID:
5986694

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