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Items: 1 to 50 of 163

1.

Wnt/β-catenin signaling enhances transcription of the CX43 gene in murine Sertoli cells.

López C, Aguilar R, Nardocci G, Cereceda K, Vander Stelt K, Slebe JC, Montecino M, Concha II.

J Cell Biochem. 2018 Nov 11. doi: 10.1002/jcb.27973. [Epub ahead of print]

PMID:
30417410
2.

Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts.

Rojas A, Sepulveda H, Henriquez B, Aguilar R, Opazo T, Nardocci G, Bustos F, Lian JB, Stein JL, Stein GS, van Zundert B, van Wijnen AJ, Allende ML, Montecino M.

J Cell Physiol. 2018 Sep 7. doi: 10.1002/jcp.27355. [Epub ahead of print]

PMID:
30256410
3.

Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and bone-related transcription factor RUNX2.

Araya HF, Sepulveda H, Lizama CO, Vega OA, Jerez S, Briceño PF, Thaler R, Riester SM, Antonelli M, Salazar-Onfray F, Rodríguez JP, Moreno RD, Montecino M, Charbonneau M, Dubois CM, Stein GS, van Wijnen AJ, Galindo MA.

J Cell Biochem. 2018 Nov;119(10):8204-8219. doi: 10.1002/jcb.26832. Epub 2018 Jun 19.

PMID:
29923217
4.

Identification of a novel long noncoding RNA that promotes osteoblast differentiation.

Nardocci G, Carrasco ME, Acevedo E, Hodar C, Meneses C, Montecino M.

J Cell Biochem. 2018 Sep;119(9):7657-7666. doi: 10.1002/jcb.27113. Epub 2018 May 28.

PMID:
29806713
5.

Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells.

Díaz-Valdivia NI, Calderón CC, Díaz JE, Lobos-González L, Sepulveda H, Ortíz RJ, Martinez S, Silva V, Maldonado HJ, Silva P, Wehinger S, Burzio VA, Torres VA, Montecino M, Leyton L, Quest AFG.

Oncotarget. 2017 Dec 5;8(67):111943-111965. doi: 10.18632/oncotarget.22955. eCollection 2017 Dec 19.

6.

Variable transcriptional responsiveness of the P2X3 receptor gene during CFA-induced inflammatory hyperalgesia.

Nuñez-Badinez P, Sepúlveda H, Diaz E, Greffrath W, Treede RD, Stehberg J, Montecino M, van Zundert B.

J Cell Biochem. 2018 May;119(5):3922-3935. doi: 10.1002/jcb.26534. Epub 2018 Jan 25.

PMID:
29219199
7.

Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer's disease mice.

Bustos FJ, Ampuero E, Jury N, Aguilar R, Falahi F, Toledo J, Ahumada J, Lata J, Cubillos P, Henríquez B, Guerra MV, Stehberg J, Neve RL, Inestrosa NC, Wyneken U, Fuenzalida M, Härtel S, Sena-Esteves M, Varela-Nallar L, Rots MG, Montecino M, van Zundert B.

Brain. 2017 Dec 1;140(12):3252-3268. doi: 10.1093/brain/awx272.

PMID:
29155979
8.

Runt-Related Transcription Factor 2 Induction During Differentiation of Wharton's Jelly Mesenchymal Stem Cells to Osteoblasts Is Regulated by Jumonji AT-Rich Interactive Domain 1B Histone Demethylase.

Busto F, Sepúlveda H, Prieto CP, Carrasco M, Díaz L, Palma J, Lattus J, Montecino M, Palma V.

Stem Cells. 2017 Dec;35(12):2430-2441. doi: 10.1002/stem.2704. Epub 2017 Sep 29. Erratum in: Stem Cells. 2018 Apr;36(4):631.

PMID:
28895234
9.

A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis.

Díaz-Jiménez D, Núñez L, De la Fuente M, Dubois-Camacho K, Sepúlveda H, Montecino M, Torres-Riquelme A, García-González P, Chnaiderman J, Vossenkamper A, MacDonald TT, Simian D, González MJ, Cidlowski JA, Quera R, Hermoso MA.

Sci Rep. 2017 Aug 31;7(1):10180. doi: 10.1038/s41598-017-10465-0.

10.
11.

Functional Annotation of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture.

Macqueen DJ, Primmer CR, Houston RD, Nowak BF, Bernatchez L, Bergseth S, Davidson WS, Gallardo-Escárate C, Goldammer T, Guiguen Y, Iturra P, Kijas JW, Koop BF, Lien S, Maass A, Martin SAM, McGinnity P, Montecino M, Naish KA, Nichols KM, Ólafsson K, Omholt SW, Palti Y, Plastow GS, Rexroad CE Rd, Rise ML, Ritchie RJ, Sandve SR, Schulte PM, Tello A, Vidal R, Vik JO, Wargelius A, Yáñez JM; FAASG Consortium.

BMC Genomics. 2017 Jun 27;18(1):484. doi: 10.1186/s12864-017-3862-8.

12.

Global gene expression analysis provides insight into local adaptation to geothermal streams in tadpoles of the Andean toad Rhinella spinulosa.

Pastenes L, Valdivieso C, Di Genova A, Travisany D, Hart A, Montecino M, Orellana A, Gonzalez M, Gutiérrez RA, Allende ML, Maass A, Méndez MA.

Sci Rep. 2017 May 16;7(1):1966. doi: 10.1038/s41598-017-01982-z.

13.

NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, and H3K27ac.

Bustos FJ, Jury N, Martinez P, Ampuero E, Campos M, Abarzúa S, Jaramillo K, Ibing S, Mardones MD, Haensgen H, Kzhyshkowska J, Tevy MF, Neve R, Sanhueza M, Varela-Nallar L, Montecino M, van Zundert B.

J Cell Physiol. 2017 Dec;232(12):3677-3692. doi: 10.1002/jcp.25843. Epub 2017 May 11.

PMID:
28160495
14.

Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing.

Dudakovic A, Gluscevic M, Paradise CR, Dudakovic H, Khani F, Thaler R, Ahmed FS, Li X, Dietz AB, Stein GS, Montecino MA, Deyle DR, Westendorf JJ, van Wijnen AJ.

Gene. 2017 Apr 20;609:28-37. doi: 10.1016/j.gene.2017.01.019. Epub 2017 Jan 27.

15.

Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice.

Dudakovic A, Camilleri ET, Riester SM, Paradise CR, Gluscevic M, O'Toole TM, Thaler R, Evans JM, Yan H, Subramaniam M, Hawse JR, Stein GS, Montecino MA, McGee-Lawrence ME, Westendorf JJ, van Wijnen AJ.

J Biol Chem. 2016 Nov 18;291(47):24594-24606. Epub 2016 Oct 10.

16.

Epigenetic Signatures at the RUNX2-P1 and Sp7 Gene Promoters Control Osteogenic Lineage Commitment of Umbilical Cord-Derived Mesenchymal Stem Cells.

Sepulveda H, Aguilar R, Prieto CP, Bustos F, Aedo S, Lattus J, van Zundert B, Palma V, Montecino M.

J Cell Physiol. 2017 Sep;232(9):2519-2527. doi: 10.1002/jcp.25627. Epub 2017 Mar 28.

PMID:
27689934
17.

Polycomb PRC2 complex mediates epigenetic silencing of a critical osteogenic master regulator in the hippocampus.

Aguilar R, Bustos FJ, Saez M, Rojas A, Allende ML, van Wijnen AJ, van Zundert B, Montecino M.

Biochim Biophys Acta. 2016 Aug;1859(8):1043-55. doi: 10.1016/j.bbagrm.2016.05.009. Epub 2016 May 20.

18.

The chromatin modifying complex CoREST/LSD1 negatively regulates notch pathway during cerebral cortex development.

Lopez CI, Saud KE, Aguilar R, Berndt FA, Cánovas J, Montecino M, Kukuljan M.

Dev Neurobiol. 2016 Dec;76(12):1360-1373. doi: 10.1002/dneu.22397. Epub 2016 May 31.

19.

Essential role of HDAC6 in the regulation of PD-L1 in melanoma.

M L, P PV, T K, M P, E S, J P, K V W, C L, F C, S D, M SKS, M M, A K, J PI, A S, E S, J W, E M S, A V.

Mol Oncol. 2016 May;10(5):735-750. doi: 10.1016/j.molonc.2015.12.012. Epub 2016 Jan 6.

20.

Genome-Wide Studies Reveal that H3K4me3 Modification in Bivalent Genes Is Dynamically Regulated during the Pluripotent Cell Cycle and Stabilized upon Differentiation.

Grandy RA, Whitfield TW, Wu H, Fitzgerald MP, VanOudenhove JJ, Zaidi SK, Montecino MA, Lian JB, van Wijnen AJ, Stein JL, Stein GS.

Mol Cell Biol. 2015 Dec 7;36(4):615-27. doi: 10.1128/MCB.00877-15. Print 2016 Feb 15.

21.

Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B.

Rojas A, Aguilar R, Henriquez B, Lian JB, Stein JL, Stein GS, van Wijnen AJ, van Zundert B, Allende ML, Montecino M.

J Biol Chem. 2015 Nov 20;290(47):28329-42. doi: 10.1074/jbc.M115.657825. Epub 2015 Oct 9.

22.

Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2.

Dudakovic A, Camilleri ET, Xu F, Riester SM, McGee-Lawrence ME, Bradley EW, Paradise CR, Lewallen EA, Thaler R, Deyle DR, Larson AN, Lewallen DG, Dietz AB, Stein GS, Montecino MA, Westendorf JJ, van Wijnen AJ.

J Biol Chem. 2015 Nov 13;290(46):27604-17. doi: 10.1074/jbc.M115.672345. Epub 2015 Sep 30.

23.

Mitotic Inheritance of mRNA Facilitates Translational Activation of the Osteogenic-Lineage Commitment Factor Runx2 in Progeny of Osteoblastic Cells.

Varela N, Aranguiz A, Lizama C, Sepulveda H, Antonelli M, Thaler R, Moreno RD, Montecino M, Stein GS, van Wijnen AJ, Galindo M.

J Cell Physiol. 2016 May;231(5):1001-14. doi: 10.1002/jcp.25188. Epub 2015 Sep 18.

24.

The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a.

Cánovas J, Berndt FA, Sepúlveda H, Aguilar R, Veloso FA, Montecino M, Oliva C, Maass JC, Sierralta J, Kukuljan M.

J Neurosci. 2015 May 13;35(19):7552-64. doi: 10.1523/JNEUROSCI.0169-15.2015.

25.

Multiple levels of epigenetic control for bone biology and pathology.

Montecino M, Stein G, Stein J, Zaidi K, Aguilar R.

Bone. 2015 Dec;81:733-738. doi: 10.1016/j.bone.2015.03.013. Epub 2015 Apr 10. Review.

26.

Prenatal stress down-regulates Reelin expression by methylation of its promoter and induces adult behavioral impairments in rats.

Palacios-García I, Lara-Vásquez A, Montiel JF, Díaz-Véliz GF, Sepúlveda H, Utreras E, Montecino M, González-Billault C, Aboitiz F.

PLoS One. 2015 Feb 13;10(2):e0117680. doi: 10.1371/journal.pone.0117680. eCollection 2015.

27.

Epigenetic pathways regulating bone homeostasis: potential targeting for intervention of skeletal disorders.

Gordon JA, Montecino MA, Aqeilan RI, Stein JL, Stein GS, Lian JB.

Curr Osteoporos Rep. 2014 Dec;12(4):496-506. doi: 10.1007/s11914-014-0240-1. Review.

28.

Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells.

Dudakovic A, Camilleri ET, Lewallen EA, McGee-Lawrence ME, Riester SM, Kakar S, Montecino M, Stein GS, Ryoo HM, Dietz AB, Westendorf JJ, van Wijnen AJ.

J Cell Physiol. 2015 Jan;230(1):52-62. doi: 10.1002/jcp.24680.

29.

Modeling acclimatization by hybrid systems: condition changes alter biological system behavior models.

Assar R, Montecino MA, Maass A, Sherman DJ.

Biosystems. 2014 Jul;121:43-53. doi: 10.1016/j.biosystems.2014.05.007. Epub 2014 Jun 2.

PMID:
24892552
30.

Symbolic extensions applied to multiscale structure of genomes.

Downarowicz T, Travisany D, Montecino M, Maass A.

Acta Biotheor. 2014 Jun;62(2):145-69. doi: 10.1007/s10441-014-9215-y. Epub 2014 Apr 13.

31.

PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors.

Bustos FJ, Varela-Nallar L, Campos M, Henriquez B, Phillips M, Opazo C, Aguayo LG, Montecino M, Constantine-Paton M, Inestrosa NC, van Zundert B.

PLoS One. 2014 Apr 4;9(4):e94037. doi: 10.1371/journal.pone.0094037. eCollection 2014.

32.

A functional N-terminal domain in C/EBPβ-LAP* is required for interacting with SWI/SNF and to repress Ric-8B gene transcription in osteoblasts.

Aguilar R, Grandy R, Meza D, Sepulveda H, Pihan P, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M.

J Cell Physiol. 2014 Oct;229(10):1521-8. doi: 10.1002/jcp.24595.

33.

Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes?

Zaidi SK, Grandy RA, Lopez-Camacho C, Montecino M, van Wijnen AJ, Lian JB, Stein JL, Stein GS.

Cancer Res. 2014 Jan 15;74(2):420-5. doi: 10.1158/0008-5472.CAN-13-2837. Epub 2014 Jan 9. Review.

34.

The dynamic architectural and epigenetic nuclear landscape: developing the genomic almanac of biology and disease.

Tai PW, Zaidi SK, Wu H, Grandy RA, Montecino M, van Wijnen AJ, Lian JB, Stein GS, Stein JL.

J Cell Physiol. 2014 Jun;229(6):711-27. doi: 10.1002/jcp.24508. Review.

35.

Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons.

Henriquez B, Bustos FJ, Aguilar R, Becerra A, Simon F, Montecino M, van Zundert B.

Mol Cell Neurosci. 2013 Nov;57:130-43. doi: 10.1016/j.mcn.2013.07.012. Epub 2013 Aug 8.

PMID:
23932971
36.

Enhanced CRAd activity using enhancer motifs driven by a nucleosome positioning sequence.

Bravo S, Núñez F, Cruzat F, Cafferata EG, De Ferrari GV, Montecino M, Podhajcer OL.

Mol Ther. 2013 Jul;21(7):1403-12. doi: 10.1038/mt.2013.93. Epub 2013 May 28.

37.

Transcription of the pain-related TRPV1 gene requires Runx1 and C/EBPβ factors.

Ugarte GD, Diaz E, Biscaia M, Stehberg J, Montecino M, van Zundert B.

J Cell Physiol. 2013 Apr;228(4):860-70. doi: 10.1002/jcp.24236.

PMID:
23018770
38.

Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene.

Hovhannisyan H, Zhang Y, Hassan MQ, Wu H, Glackin C, Lian JB, Stein JL, Montecino M, Stein GS, van Wijnen AJ.

J Cell Physiol. 2013 Feb;228(2):313-21. doi: 10.1002/jcp.22109.

39.

Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle.

Medina R, Ghule PN, Cruzat F, Barutcu AR, Montecino M, Stein JL, van Wijnen AJ, Stein GS.

Mol Cell Biol. 2012 Oct;32(19):3860-71. doi: 10.1128/MCB.00736-12. Epub 2012 Jul 23.

40.

Ric-8: different cellular roles for a heterotrimeric G-protein GEF.

Hinrichs MV, Torrejón M, Montecino M, Olate J.

J Cell Biochem. 2012 Sep;113(9):2797-805. doi: 10.1002/jcb.24162. Review.

PMID:
22511245
41.

The architectural organization of human stem cell cycle regulatory machinery.

Stein GS, Stein JL, van J Wijnen A, Lian JB, Montecino M, Medina R, Kapinas K, Ghule P, Grandy R, Zaidi SK, Becker KA.

Curr Pharm Des. 2012;18(13):1679-85. Review.

42.

Reusing and composing models of cell fate regulation of human bone precursor cells.

Assar R, Leisewitz AV, Garcia A, Inestrosa NC, Montecino MA, Sherman DJ.

Biosystems. 2012 Apr-Jun;108(1-3):63-72. doi: 10.1016/j.biosystems.2012.01.008. Epub 2012 Jan 27.

PMID:
22309764
43.

Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.

van der Deen M, Akech J, Lapointe D, Gupta S, Young DW, Montecino MA, Galindo M, Lian JB, Stein JL, Stein GS, van Wijnen AJ.

J Biol Chem. 2012 Feb 10;287(7):4503-17. doi: 10.1074/jbc.M111.287771. Epub 2011 Dec 9.

44.

Runx1 and C/EBPβ transcription factors directly up-regulate P2X3 gene transcription.

Ugarte GD, Opazo T, Leisewitz F, van Zundert B, Montecino M.

J Cell Physiol. 2012 Apr;227(4):1645-52. doi: 10.1002/jcp.22882.

PMID:
21678417
45.

The Ric-8B gene is highly expressed in proliferating preosteoblastic cells and downregulated during osteoblast differentiation in a SWI/SNF- and C/EBPbeta-mediated manner.

Grandy R, Sepulveda H, Aguilar R, Pihan P, Henriquez B, Olate J, Montecino M.

Mol Cell Biol. 2011 Jul;31(14):2997-3008. doi: 10.1128/MCB.05096-11. Epub 2011 May 23.

46.

Epigenetic regulation of early osteogenesis and mineralized tissue formation by a HOXA10-PBX1-associated complex.

Gordon JA, Hassan MQ, Koss M, Montecino M, Selleri L, van Wijnen AJ, Stein JL, Stein GS, Lian JB.

Cells Tissues Organs. 2011;194(2-4):146-50. doi: 10.1159/000324790. Epub 2011 May 19.

47.

Wnt/β-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells.

Nuñez F, Bravo S, Cruzat F, Montecino M, De Ferrari GV.

PLoS One. 2011 Apr 6;6(4):e18562. doi: 10.1371/journal.pone.0018562.

48.

Bookmarking the genome: maintenance of epigenetic information.

Zaidi SK, Young DW, Montecino M, van Wijnen AJ, Stein JL, Lian JB, Stein GS.

J Biol Chem. 2011 May 27;286(21):18355-61. doi: 10.1074/jbc.R110.197061. Epub 2011 Mar 24. Review.

49.

C/EBPβ binds the P1 promoter of the Runx2 gene and up-regulates Runx2 transcription in osteoblastic cells.

Henriquez B, Hepp M, Merino P, Sepulveda H, van Wijnen AJ, Lian JB, Stein GS, Stein JL, Montecino M.

J Cell Physiol. 2011 Nov;226(11):3043-52. doi: 10.1002/jcp.22652.

50.

An architectural genetic and epigenetic perspective.

Stein GS, Stein JL, van Wijnen AJ, Lian JB, Zaidi SK, Nickerson JA, Montecino MA, Young DW.

Integr Biol (Camb). 2011 Apr;3(4):297-303. doi: 10.1039/c0ib00103a. Epub 2010 Dec 24. Review.

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