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Items: 6


Improvement of Antitumor Therapies Based on Vaccines and Immune-Checkpoint Inhibitors by Counteracting Tumor-Immunostimulation.

Chiarella P, Vermeulen M, Montagna DR, Vallecorsa P, Strazza AR, Meiss RP, Bustuoabad OD, Ruggiero RA, Prehn RT.

Front Oncol. 2018 Jan 26;8:6. doi: 10.3389/fonc.2018.00006. eCollection 2018.


Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis.

Gueron G, Anselmino N, Chiarella P, Ortiz EG, Lage Vickers S, Paez AV, Giudice J, Contin MD, Leonardi D, Jaworski F, Manzano V, Strazza A, Montagna DR, Labanca E, Cotignola J, D Accorso N, Woloszynska-Read A, Navone N, Meiss RP, Ruggiero R, Vazquez E.

Cell Death Dis. 2018 Feb 2;9(2):140. doi: 10.1038/s41419-017-0147-8.


The amyloid-beta forming tripeptide cleavage mechanism of γ-secretase.

Bolduc DM, Montagna DR, Seghers MC, Wolfe MS, Selkoe DJ.

Elife. 2016 Aug 31;5. pii: e17578. doi: 10.7554/eLife.17578.


Nicastrin functions to sterically hinder γ-secretase-substrate interactions driven by substrate transmembrane domain.

Bolduc DM, Montagna DR, Gu Y, Selkoe DJ, Wolfe MS.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E509-18. doi: 10.1073/pnas.1512952113. Epub 2015 Dec 22.


Alternative polyadenylation and miR-34 family members regulate tau expression.

Dickson JR, Kruse C, Montagna DR, Finsen B, Wolfe MS.

J Neurochem. 2013 Dec;127(6):739-49. doi: 10.1111/jnc.12437. Epub 2013 Sep 18.


A G-rich element forms a G-quadruplex and regulates BACE1 mRNA alternative splicing.

Fisette JF, Montagna DR, Mihailescu MR, Wolfe MS.

J Neurochem. 2012 Jun;121(5):763-73. doi: 10.1111/j.1471-4159.2012.07680.x. Epub 2012 Mar 13.

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