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Items: 1 to 50 of 59

1.
2.

Cloning and functional characterization of an elovl4-like gene involved in the biosynthesis of long-chain polyunsaturated fatty acids in the swimming crab Portunus trituberculatus.

Sun P, Zhou Q, Monroig Ó, Navarro JC, Jin M, Yuan Y, Wang X, Jiao L.

Comp Biochem Physiol B Biochem Mol Biol. 2020 Apr;242:110408. doi: 10.1016/j.cbpb.2020.110408. Epub 2020 Jan 17.

PMID:
31958500
3.

The catadromous teleost Anguilla japonica has a complete enzymatic repertoire for the biosynthesis of docosahexaenoic acid from α-linolenic acid: Cloning and functional characterization of an Elovl2 elongase.

Xu W, Wang S, You C, Zhang Y, Monroig Ó, Tocher DR, Li Y.

Comp Biochem Physiol B Biochem Mol Biol. 2020 Feb;240:110373. doi: 10.1016/j.cbpb.2019.110373. Epub 2019 Oct 31.

PMID:
31678268
4.

Molecular and functional characterisation of a putative elovl4 gene and its expression in response to dietary fatty acid profile in Atlantic bluefin tuna (Thunnus thynnus).

Betancor MB, Oboh A, Ortega A, Mourente G, Navarro JC, de la Gándara F, Tocher DR, Monroig Ó.

Comp Biochem Physiol B Biochem Mol Biol. 2020 Feb;240:110372. doi: 10.1016/j.cbpb.2019.110372. Epub 2019 Oct 24.

PMID:
31669375
5.

Sp1 is Involved in Vertebrate LC-PUFA Biosynthesis by Upregulating the Expression of Liver Desaturase and Elongase Genes.

Li Y, Zhao J, Dong Y, Yin Z, Li Y, Liu Y, You C, Monroig Ó, Tocher DR, Wang S.

Int J Mol Sci. 2019 Oct 12;20(20). pii: E5066. doi: 10.3390/ijms20205066.

6.

Effects of dietary lipid level on growth, fatty acid profiles, antioxidant capacity and expression of genes involved in lipid metabolism in juvenile swimming crab, Portunus trituberculatus.

Sun P, Jin M, Jiao L, Monroig Ó, Navarro JC, Tocher DR, Betancor MB, Wang X, Yuan Y, Zhou Q.

Br J Nutr. 2020 Jan 28;123(2):149-160. doi: 10.1017/S0007114519002563.

PMID:
31603067
7.

Gene identification and functional characterization of a Δ12 fatty acid desaturase in Tetrahymena thermophila and its influence in homeoviscous adaptation to low temperature.

Sanchez Granel ML, Cánepa C, Cid NG, Navarro JC, Monroig Ó, Verstraeten SV, Nudel CB, Nusblat AD.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Nov;1864(11):1644-1655. doi: 10.1016/j.bbalip.2019.08.003. Epub 2019 Aug 14.

PMID:
31421180
8.

Functional diversification of teleost Fads2 fatty acyl desaturases occurs independently of the trophic level.

Garrido D, Kabeya N, Betancor MB, Pérez JA, Acosta NG, Tocher DR, Rodríguez C, Monroig Ó.

Sci Rep. 2019 Aug 1;9(1):11199. doi: 10.1038/s41598-019-47709-0.

9.

A key metabolic gene for recurrent freshwater colonization and radiation in fishes.

Ishikawa A, Kabeya N, Ikeya K, Kakioka R, Cech JN, Osada N, Leal MC, Inoue J, Kume M, Toyoda A, Tezuka A, Nagano AJ, Yamasaki YY, Suzuki Y, Kokita T, Takahashi H, Lucek K, Marques D, Takehana Y, Naruse K, Mori S, Monroig O, Ladd N, Schubert CJ, Matthews B, Peichel CL, Seehausen O, Yoshizaki G, Kitano J.

Science. 2019 May 31;364(6443):886-889. doi: 10.1126/science.aau5656.

PMID:
31147520
10.

Methyl-end desaturases with ∆12 and ω3 regioselectivities enable the de novo PUFA biosynthesis in the cephalopod Octopus vulgaris.

Garrido D, Kabeya N, Hontoria F, Navarro JC, Reis DB, Martín MV, Rodríguez C, Almansa E, Monroig Ó.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Aug;1864(8):1134-1144. doi: 10.1016/j.bbalip.2019.04.012. Epub 2019 Apr 30.

PMID:
31048041
11.

MicroRNAs Involved in the Regulation of LC-PUFA Biosynthesis in Teleosts: miR-33 Enhances LC-PUFA Biosynthesis in Siganus canaliculatus by Targeting insig1 which in Turn Upregulates srebp1.

Sun JJ, Zheng LG, Chen CY, Zhang JY, You CH, Zhang QH, Ma HY, Monroig Ó, Tocher DR, Wang SQ, Li YY.

Mar Biotechnol (NY). 2019 Aug;21(4):475-487. doi: 10.1007/s10126-019-09895-w. Epub 2019 Apr 24.

PMID:
31020472
12.

Functional characterisation of two Δ12-desaturases demonstrates targeted production of linoleic acid as pheromone precursor in Nasonia.

Semmelmann F, Kabeya N, Malcicka M, Bruckmann A, Broschwitz B, Straub K, Merkl R, Monroig O, Sterner R, Ruther J, Ellers J.

J Exp Biol. 2019 May 16;222(Pt 10). pii: jeb201038. doi: 10.1242/jeb.201038.

13.

Biosynthesis of long-chain polyunsaturated fatty acids in the razor clam Sinonovacula constricta: Characterization of four fatty acyl elongases and a novel desaturase capacity.

Ran Z, Xu J, Liao K, Monroig Ó, Navarro JC, Oboh A, Jin M, Zhou Q, Zhou C, Tocher DR, Yan X.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Aug;1864(8):1083-1090. doi: 10.1016/j.bbalip.2019.04.004. Epub 2019 Apr 16.

PMID:
31002943
14.

miR-24 is involved in vertebrate LC-PUFA biosynthesis as demonstrated in marine teleost Siganus canaliculatus.

Chen C, Wang S, Zhang M, Chen B, You C, Xie D, Liu Y, Monroig Ó, Tocher DR, Waiho K, Li Y.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):619-628. doi: 10.1016/j.bbalip.2019.01.010. Epub 2019 Jan 23.

PMID:
30684680
15.

Identification of very long-chain (>C24) fatty acid methyl esters using gas chromatography coupled to quadrupole/time-of-flight mass spectrometry with atmospheric pressure chemical ionization source.

Garlito B, Portolés T, Niessen WMA, Navarro JC, Hontoria F, Monroig Ó, Varó I, Serrano R.

Anal Chim Acta. 2019 Mar 21;1051:103-109. doi: 10.1016/j.aca.2018.11.001. Epub 2018 Nov 5.

PMID:
30661606
16.

Retention of fatty acyl desaturase 1 (fads1) in Elopomorpha and Cyclostomata provides novel insights into the evolution of long-chain polyunsaturated fatty acid biosynthesis in vertebrates.

Lopes-Marques M, Kabeya N, Qian Y, Ruivo R, Santos MM, Venkatesh B, Tocher DR, Castro LFC, Monroig Ó.

BMC Evol Biol. 2018 Oct 19;18(1):157. doi: 10.1186/s12862-018-1271-5.

17.

"Out of the Can": A Draft Genome Assembly, Liver Transcriptome, and Nutrigenomics of the European Sardine, Sardina pilchardus.

Machado AM, Tørresen OK, Kabeya N, Couto A, Petersen B, Felício M, Campos PF, Fonseca E, Bandarra N, Lopes-Marques M, Ferraz R, Ruivo R, Fonseca MM, Jentoft S, Monroig Ó, da Fonseca RR, C Castro LF.

Genes (Basel). 2018 Oct 9;9(10). pii: E485. doi: 10.3390/genes9100485.

18.

A complete enzymatic capacity for long-chain polyunsaturated fatty acid biosynthesis is present in the Amazonian teleost tambaqui, Colossoma macropomum.

Ferraz RB, Kabeya N, Lopes-Marques M, Machado AM, Ribeiro RA, Salaro AL, Ozório R, Castro LFC, Monroig Ó.

Comp Biochem Physiol B Biochem Mol Biol. 2019 Jan;227:90-97. doi: 10.1016/j.cbpb.2018.09.003. Epub 2018 Oct 2.

PMID:
30290221
19.

Pparγ Is Involved in the Transcriptional Regulation of Liver LC-PUFA Biosynthesis by Targeting the Δ6Δ5 Fatty Acyl Desaturase Gene in the Marine Teleost Siganus canaliculatus.

Li Y, Yin Z, Dong Y, Wang S, Monroig Ó, Tocher DR, You C.

Mar Biotechnol (NY). 2019 Feb;21(1):19-29. doi: 10.1007/s10126-018-9854-0. Epub 2018 Sep 11.

PMID:
30206714
20.

Genes for de novo biosynthesis of omega-3 polyunsaturated fatty acids are widespread in animals.

Kabeya N, Fonseca MM, Ferrier DEK, Navarro JC, Bay LK, Francis DS, Tocher DR, Castro LFC, Monroig Ó.

Sci Adv. 2018 May 2;4(5):eaar6849. doi: 10.1126/sciadv.aar6849. eCollection 2018 May.

21.

Characteristics of the fads2 gene promoter in marine teleost Epinephelus coioides and role of Sp1-binding site in determining promoter activity.

Xie D, Fu Z, Wang S, You C, Monroig Ó, Tocher DR, Li Y.

Sci Rep. 2018 Mar 28;8(1):5305. doi: 10.1038/s41598-018-23668-w.

22.

Hnf4α is involved in the regulation of vertebrate LC-PUFA biosynthesis: insights into the regulatory role of Hnf4α on expression of liver fatty acyl desaturases in the marine teleost Siganus canaliculatus.

Wang S, Chen J, Jiang D, Zhang Q, You C, Tocher DR, Monroig Ó, Dong Y, Li Y.

Fish Physiol Biochem. 2018 Jun;44(3):805-815. doi: 10.1007/s10695-018-0470-8. Epub 2018 Jan 19.

PMID:
29352428
23.

Cloning and characterization of ∆6/∆5 fatty acyl desaturase (Fad) gene promoter in the marine teleost Siganus canaliculatus.

Dong Y, Zhao J, Chen J, Wang S, Liu Y, Zhang Q, You C, Monroig Ó, Tocher DR, Li Y.

Gene. 2018 Mar 20;647:174-180. doi: 10.1016/j.gene.2018.01.031. Epub 2018 Jan 9.

PMID:
29329928
24.

The compositional and metabolic responses of gilthead seabream (Sparus aurata) to a gradient of dietary fish oil and associated n-3 long-chain PUFA content.

Houston SJS, Karalazos V, Tinsley J, Betancor MB, Martin SAM, Tocher DR, Monroig O.

Br J Nutr. 2017 Dec;118(12):1010-1022. doi: 10.1017/S0007114517002975. Epub 2017 Nov 20.

PMID:
29151385
25.

Elongation of very Long-Chain (>C24) Fatty Acids in Clarias gariepinus: Cloning, Functional Characterization and Tissue Expression of elovl4 Elongases.

Oboh A, Navarro JC, Tocher DR, Monroig O.

Lipids. 2017 Oct;52(10):837-848. doi: 10.1007/s11745-017-4289-3. Epub 2017 Aug 30.

26.

Molecular and functional characterisation of two elovl4 elongases involved in the biosynthesis of very long-chain (>C24) polyunsaturated fatty acids in black seabream Acanthopagrus schlegelii.

Jin M, Monroig Ó, Navarro JC, Tocher DR, Zhou QC.

Comp Biochem Physiol B Biochem Mol Biol. 2017 Oct;212:41-50. doi: 10.1016/j.cbpb.2017.06.008. Epub 2017 Jun 29.

PMID:
28668330
27.

Two alternative pathways for docosahexaenoic acid (DHA, 22:6n-3) biosynthesis are widespread among teleost fish.

Oboh A, Kabeya N, Carmona-Antoñanzas G, Castro LFC, Dick JR, Tocher DR, Monroig O.

Sci Rep. 2017 Jun 20;7(1):3889. doi: 10.1038/s41598-017-04288-2.

28.

Dietary Effect on the Proteome of the Common Octopus (Octopus vulgaris) Paralarvae.

Varó I, Cardenete G, Hontoria F, Monroig Ó, Iglesias J, Otero JJ, Almansa E, Navarro JC.

Front Physiol. 2017 May 17;8:309. doi: 10.3389/fphys.2017.00309. eCollection 2017.

29.

Functional characterization and differential nutritional regulation of putative Elovl5 and Elovl4 elongases in large yellow croaker (Larimichthys crocea).

Li S, Monroig Ó, Wang T, Yuan Y, Carlos Navarro J, Hontoria F, Liao K, Tocher DR, Mai K, Xu W, Ai Q.

Sci Rep. 2017 May 23;7(1):2303. doi: 10.1038/s41598-017-02646-8.

30.

Dietary DHA/EPA ratio affected tissue fatty acid profiles, antioxidant capacity, hematological characteristics and expression of lipid-related genes but not growth in juvenile black seabream (Acanthopagrus schlegelii).

Jin M, Monroig Ó, Lu Y, Yuan Y, Li Y, Ding L, Tocher DR, Zhou Q.

PLoS One. 2017 Apr 21;12(4):e0176216. doi: 10.1371/journal.pone.0176216. eCollection 2017.

31.

Biosynthesis of Polyunsaturated Fatty Acids in Octopus vulgaris: Molecular Cloning and Functional Characterisation of a Stearoyl-CoA Desaturase and an Elongation of Very Long-Chain Fatty Acid 4 Protein.

Monroig Ó, de Llanos R, Varó I, Hontoria F, Tocher DR, Puig S, Navarro JC.

Mar Drugs. 2017 Mar 21;15(3). pii: E82. doi: 10.3390/md15030082.

32.

Biosynthesis of Polyunsaturated Fatty Acids in Sea Urchins: Molecular and Functional Characterisation of Three Fatty Acyl Desaturases from Paracentrotus lividus (Lamark 1816).

Kabeya N, Sanz-Jorquera A, Carboni S, Davie A, Oboh A, Monroig O.

PLoS One. 2017 Jan 4;12(1):e0169374. doi: 10.1371/journal.pone.0169374. eCollection 2017.

33.

Lipid Composition of Oil Extracted from Wasted Norway Lobster (Nephrops norvegicus) Heads and Comparison with Oil Extracted from Antarctic Krill (Euphasia superba).

Albalat A, Nadler LE, Foo N, Dick JR, Watts AJ, Philp H, Neil DM, Monroig O.

Mar Drugs. 2016 Dec 1;14(12). pii: E219.

34.

Molecular and functional characterization of a fads2 orthologue in the Amazonian teleost, Arapaima gigas.

Lopes-Marques M, Ozório R, Amaral R, Tocher DR, Monroig Ó, Castro LF.

Comp Biochem Physiol B Biochem Mol Biol. 2017 Jan;203:84-91. doi: 10.1016/j.cbpb.2016.09.007. Epub 2016 Sep 29.

35.

The miR-33 gene is identified in a marine teleost: a potential role in regulation of LC-PUFA biosynthesis in Siganus canaliculatus.

Zhang Q, You C, Wang S, Dong Y, Monroig Ó, Tocher DR, Li Y.

Sci Rep. 2016 Sep 19;6:32909. doi: 10.1038/srep32909.

36.

Hepatocyte Nuclear Factor 4α (HNF4α) Is a Transcription Factor of Vertebrate Fatty Acyl Desaturase Gene as Identified in Marine Teleost Siganus canaliculatus.

Dong Y, Wang S, Chen J, Zhang Q, Liu Y, You C, Monroig Ó, Tocher DR, Li Y.

PLoS One. 2016 Jul 29;11(7):e0160361. doi: 10.1371/journal.pone.0160361. eCollection 2016.

37.

Cloning and Characterization of Lxr and Srebp1, and Their Potential Roles in Regulation of LC-PUFA Biosynthesis in Rabbitfish Siganus canaliculatus.

Zhang Q, You C, Liu F, Zhu W, Wang S, Xie D, Monroig Ó, Tocher DR, Li Y.

Lipids. 2016 Sep;51(9):1051-63. doi: 10.1007/s11745-016-4176-3. Epub 2016 Jul 27.

PMID:
27464514
38.

Long-chain polyunsaturated fatty acid biosynthesis in the euryhaline herbivorous teleost Scatophagus argus: Functional characterization, tissue expression and nutritional regulation of two fatty acyl elongases.

Xie D, Chen F, Lin S, You C, Wang S, Zhang Q, Monroig Ó, Tocher DR, Li Y.

Comp Biochem Physiol B Biochem Mol Biol. 2016 Aug;198:37-45. doi: 10.1016/j.cbpb.2016.03.009. Epub 2016 Apr 3.

PMID:
27050407
39.

Isolation and Functional Characterisation of a fads2 in Rainbow Trout (Oncorhynchus mykiss) with Δ5 Desaturase Activity.

Abdul Hamid NK, Carmona-Antoñanzas G, Monroig Ó, Tocher DR, Turchini GM, Donald JA.

PLoS One. 2016 Mar 4;11(3):e0150770. doi: 10.1371/journal.pone.0150770. eCollection 2016.

40.

Evolutionary functional elaboration of the Elovl2/5 gene family in chordates.

Monroig Ó, Lopes-Marques M, Navarro JC, Hontoria F, Ruivo R, Santos MM, Venkatesh B, Tocher DR, Castro LF.

Sci Rep. 2016 Feb 9;6:20510. doi: 10.1038/srep20510.

41.

Long-chain polyunsaturated fatty acid biosynthesis in chordates: Insights into the evolution of Fads and Elovl gene repertoire.

Castro LF, Tocher DR, Monroig O.

Prog Lipid Res. 2016 Apr;62:25-40. doi: 10.1016/j.plipres.2016.01.001. Epub 2016 Jan 6. Review.

PMID:
26769304
42.

Diversification of substrate specificities in teleostei Fads2: characterization of Δ4 and Δ6Δ5 desaturases of Chirostoma estor.

Fonseca-Madrigal J, Navarro JC, Hontoria F, Tocher DR, Martínez-Palacios CA, Monroig Ó.

J Lipid Res. 2014 Jul;55(7):1408-19. doi: 10.1194/jlr.M049791. Epub 2014 May 2.

43.

miR-17 is involved in the regulation of LC-PUFA biosynthesis in vertebrates: effects on liver expression of a fatty acyl desaturase in the marine teleost Siganus canaliculatus.

Zhang Q, Xie D, Wang S, You C, Monroig O, Tocher DR, Li Y.

Biochim Biophys Acta. 2014 Jul;1841(7):934-43. doi: 10.1016/j.bbalip.2014.03.009. Epub 2014 Mar 28.

PMID:
24681164
44.

Cloning, functional characterization and nutritional regulation of Δ6 fatty acyl desaturase in the herbivorous euryhaline teleost Scatophagus argus.

Xie D, Chen F, Lin S, Wang S, You C, Monroig Ó, Tocher DR, Li Y.

PLoS One. 2014 Mar 3;9(3):e90200. doi: 10.1371/journal.pone.0090200. eCollection 2014.

45.

Biosynthesis of polyunsaturated fatty acids in marine invertebrates: recent advances in molecular mechanisms.

Monroig Ó, Tocher DR, Navarro JC.

Mar Drugs. 2013 Oct 21;11(10):3998-4018. doi: 10.3390/md11103998. Review.

46.

Studies on the characterisation of biomarkers of nutritionally-derived stress in paralarval cultures of the common octopus (Octopus vulgaris).

Varó I, Navarro JC, Iglesias J, Otero JJ, Sánchez J, Almansa E, Monroig O, Hontoria F, Morales AE, Cardenete G.

Commun Agric Appl Biol Sci. 2013;78(4):473-6. No abstract available.

PMID:
25141745
47.

Endogenous metabolism of unsaturated fatty acids in Artemia nauplii as determined through incubation with 14C-labelled fatty acid substrates.

Reis DB, Acosta NG, Almansa E, Navarro JC, Tocher DR, Monroig O, Andrade JP, Sykes AV, Rodríguez C.

Commun Agric Appl Biol Sci. 2013;78(4):392-5. No abstract available.

PMID:
25141721
48.

Investigating the essential fatty acid requirements of the cephalopod Sepia officinalis: a molecular approach.

Monroig O, Hontoria F, Varó I, Tocher DR, Navarro JC.

Commun Agric Appl Biol Sci. 2013;78(4):286-9. No abstract available.

PMID:
25141692
49.

Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates.

Castro LF, Monroig Ó, Leaver MJ, Wilson J, Cunha I, Tocher DR.

PLoS One. 2012;7(2):e31950. doi: 10.1371/journal.pone.0031950. Epub 2012 Feb 22.

50.

Identification of a Δ5-like fatty acyl desaturase from the cephalopod Octopus vulgaris (Cuvier 1797) involved in the biosynthesis of essential fatty acids.

Monroig O, Navarro JC, Dick JR, Alemany F, Tocher DR.

Mar Biotechnol (NY). 2012 Aug;14(4):411-22. doi: 10.1007/s10126-011-9423-2. Epub 2011 Dec 9.

PMID:
22160425

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