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Items: 13


Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.

Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC.

Nature. 2017 Apr 6;544(7648):124. doi: 10.1038/nature22066. Epub 2017 Mar 22. No abstract available.


Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells.

Galloway NL, Doitsh G, Monroe KM, Yang Z, Muñoz-Arias I, Levy DN, Greene WC.

Cell Rep. 2015 Sep 8;12(10):1555-1563. doi: 10.1016/j.celrep.2015.08.011. Epub 2015 Aug 28.


Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.

Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC.

Nature. 2014 Jan 23;505(7484):509-14. doi: 10.1038/nature12940. Erratum in: Nature. 2017 Apr 6;544(7648):124.


IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV.

Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC.

Science. 2014 Jan 24;343(6169):428-32. doi: 10.1126/science.1243640. Epub 2013 Dec 19.


Mummy, A UDP-N-acetylglucosamine pyrophosphorylase, modulates DPP signaling in the embryonic epidermis of Drosophila.

Humphreys GB, Jud MC, Monroe KM, Kimball SS, Higley M, Shipley D, Vrablik MC, Bates KL, Letsou A.

Dev Biol. 2013 Sep 15;381(2):434-45. doi: 10.1016/j.ydbio.2013.06.006. Epub 2013 Jun 21.


The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.

Diner EJ, Burdette DL, Wilson SC, Monroe KM, Kellenberger CA, Hyodo M, Hayakawa Y, Hammond MC, Vance RE.

Cell Rep. 2013 May 30;3(5):1355-61. doi: 10.1016/j.celrep.2013.05.009. Epub 2013 May 23.


STING is a direct innate immune sensor of cyclic di-GMP.

Burdette DL, Monroe KM, Sotelo-Troha K, Iwig JS, Eckert B, Hyodo M, Hayakawa Y, Vance RE.

Nature. 2011 Sep 25;478(7370):515-8. doi: 10.1038/nature10429.


NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways.

Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA, Gris D, Roney KE, Zimmermann AG, Bowzard JB, Ranjan P, Monroe KM, Pickles RJ, Sambhara S, Ting JP.

Immunity. 2011 Jun 24;34(6):854-65. doi: 10.1016/j.immuni.2011.03.026.


The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides.

Sauer JD, Sotelo-Troha K, von Moltke J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE.

Infect Immun. 2011 Feb;79(2):688-94. doi: 10.1128/IAI.00999-10. Epub 2010 Nov 22.


Induction of type I interferons by bacteria.

Monroe KM, McWhirter SM, Vance RE.

Cell Microbiol. 2010 Jul;12(7):881-90. doi: 10.1111/j.1462-5822.2010.01478.x. Epub 2010 May 6. Review.


Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila.

Monroe KM, McWhirter SM, Vance RE.

PLoS Pathog. 2009 Nov;5(11):e1000665. doi: 10.1371/journal.ppat.1000665. Epub 2009 Nov 20.


A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP.

McWhirter SM, Barbalat R, Monroe KM, Fontana MF, Hyodo M, Joncker NT, Ishii KJ, Akira S, Colonna M, Chen ZJ, Fitzgerald KA, Hayakawa Y, Vance RE.

J Exp Med. 2009 Aug 31;206(9):1899-911. doi: 10.1084/jem.20082874. Epub 2009 Aug 3.


Dissociation of angiotensin II-stimulated activation of mitogen-activated protein kinase kinase from vascular contraction.

Watts SW, Florian JA, Monroe KM.

J Pharmacol Exp Ther. 1998 Sep;286(3):1431-8.


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