Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41


Within-host evolution of bovine Staphylococcus aureus selects for a SigB-deficient pathotype characterized by reduced virulence but enhanced proteolytic activity and biofilm formation.

Marbach H, Mayer K, Vogl C, Lee JYH, Monk IR, Sordelli DO, Buzzola FR, Ehling-Schulz M, Grunert T.

Sci Rep. 2019 Sep 17;9(1):13479. doi: 10.1038/s41598-019-49981-6.


Unstable chromosome rearrangements in Staphylococcus aureus cause phenotype switching associated with persistent infections.

Guérillot R, Kostoulias X, Donovan L, Li L, Carter GP, Hachani A, Vandelannoote K, Giulieri S, Monk IR, Kunimoto M, Starrs L, Burgio G, Seemann T, Peleg AY, Stinear TP, Howden BP.

Proc Natl Acad Sci U S A. 2019 Sep 16. pii: 201904861. doi: 10.1073/pnas.1904861116. [Epub ahead of print]


Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus.

Monk IR, Shaikh N, Begg SL, Gajdiss M, Sharkey LKR, Lee JYH, Pidot SJ, Seemann T, Kuiper M, Winnen B, Hvorup R, Collins BM, Bierbaum G, Udagedara SR, Morey JR, Pulyani N, Howden BP, Maher MJ, McDevitt CA, King GF, Stinear TP.

Nat Commun. 2019 Jul 11;10(1):3067. doi: 10.1038/s41467-019-10932-4.


Genomewide Profiling of the Enterococcus faecalis Transcriptional Response to Teixobactin Reveals CroRS as an Essential Regulator of Antimicrobial Tolerance.

Darnell RL, Knottenbelt MK, Todd Rose FO, Monk IR, Stinear TP, Cook GM.

mSphere. 2019 May 8;4(3). pii: e00228-19. doi: 10.1128/mSphere.00228-19.


Evolution of Daptomycin Resistance in Coagulase-Negative Staphylococci Involves Mutations of the Essential Two-Component Regulator WalKR.

Jiang JH, Dexter C, Cameron DR, Monk IR, Baines SL, Abbott IJ, Spelman DW, Kostoulias X, Nethercott C, Howden BP, Peleg AY.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e01926-18. doi: 10.1128/AAC.01926-18. Print 2019 Mar.


Staphylococcus aureus Superantigen-Like Protein SSL1: A Toxic Protease.

Tang A, Caballero AR, Bierdeman MA, Marquart ME, Foster TJ, Monk IR, O'Callaghan RJ.

Pathogens. 2019 Jan 1;8(1). pii: E2. doi: 10.3390/pathogens8010002.


Global spread of three multidrug-resistant lineages of Staphylococcus epidermidis.

Lee JYH, Monk IR, Gonçalves da Silva A, Seemann T, Chua KYL, Kearns A, Hill R, Woodford N, Bartels MD, Strommenger B, Laurent F, Dodémont M, Deplano A, Patel R, Larsen AR, Korman TM, Stinear TP, Howden BP.

Nat Microbiol. 2018 Oct;3(10):1175-1185. doi: 10.1038/s41564-018-0230-7. Epub 2018 Sep 3.


Genomic Analysis of Multiresistant Staphylococcus capitis Associated with Neonatal Sepsis.

Carter GP, Ussher JE, Da Silva AG, Baines SL, Heffernan H, Riley TV, Broadbent R, van der Linden A, Lee J, Monk IR, Stinear TP, Howden BP, Williamson DA.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e00898-18. doi: 10.1128/AAC.00898-18. Print 2018 Nov.


Increasing tolerance of hospital Enterococcus faecium to handwash alcohols.

Pidot SJ, Gao W, Buultjens AH, Monk IR, Guerillot R, Carter GP, Lee JYH, Lam MMC, Grayson ML, Ballard SA, Mahony AA, Grabsch EA, Kotsanas D, Korman TM, Coombs GW, Robinson JO, Gonçalves da Silva A, Seemann T, Howden BP, Johnson PDR, Stinear TP.

Sci Transl Med. 2018 Aug 1;10(452). pii: eaar6115. doi: 10.1126/scitranslmed.aar6115.


Correction: Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation.

Heilbronner S, Monk IR, Brozyna JR, Heinrichs DE, Skaar EP, Peschel A, Foster TJ.

PLoS Genet. 2018 Jul 27;14(7):e1007564. doi: 10.1371/journal.pgen.1007564. eCollection 2018 Jul.


Daptomycin selects for genetic and phenotypic adaptations leading to antibiotic tolerance in MRSA.

Berti AD, Shukla N, Rottier AD, McCrone JS, Turner HM, Monk IR, Baines SL, Howden BP, Proctor RA, Rose WE.

J Antimicrob Chemother. 2018 Aug 1;73(8):2030-2033. doi: 10.1093/jac/dky148.


Topical Antibiotic Use Coselects for the Carriage of Mobile Genetic Elements Conferring Resistance to Unrelated Antimicrobials in Staphylococcus aureus.

Carter GP, Schultz MB, Baines SL, Gonçalves da Silva A, Heffernan H, Tiong A, Pham PH, Monk IR, Stinear TP, Howden BP, Williamson DA.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e02000-17. doi: 10.1128/AAC.02000-17. Print 2018 Feb.


Functional analysis of the first complete genome sequence of a multidrug resistant sequence type 2 Staphylococcus epidermidis.

Lee JYH, Monk IR, Pidot SJ, Singh S, Chua KYL, Seemann T, Stinear TP, Howden BP.

Microb Genom. 2016 Sep 20;2(9):e000077. doi: 10.1099/mgen.0.000077. eCollection 2016 Sep.


Vancomycin-intermediate Staphylococcus aureus isolates are attenuated for virulence when compared with susceptible progenitors.

Cameron DR, Lin YH, Trouillet-Assant S, Tafani V, Kostoulias X, Mouhtouris E, Skinner N, Visvanathan K, Baines SL, Howden B, Monk IR, Laurent F, Stinear TP, Howden BP, Peleg AY.

Clin Microbiol Infect. 2017 Oct;23(10):767-773. doi: 10.1016/j.cmi.2017.03.027. Epub 2017 Apr 7.


Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana.

Kpeli G, Buultjens AH, Giulieri S, Owusu-Mireku E, Aboagye SY, Baines SL, Seemann T, Bulach D, Gonçalves da Silva A, Monk IR, Howden BP, Pluschke G, Yeboah-Manu D, Stinear T.

PeerJ. 2017 Feb 28;5:e3047. doi: 10.7717/peerj.3047. eCollection 2017.


Correspondence: Spontaneous secondary mutations confound analysis of the essential two-component system WalKR in Staphylococcus aureus.

Monk IR, Howden BP, Seemann T, Stinear TP.

Nat Commun. 2017 Feb 6;8:14403. doi: 10.1038/ncomms14403. No abstract available.


Evolutionary origins of the emergent ST796 clone of vancomycin resistant Enterococcus faecium.

Buultjens AH, Lam MM, Ballard S, Monk IR, Mahony AA, Grabsch EA, Grayson ML, Pang S, Coombs GW, Robinson JO, Seemann T, Johnson PD, Howden BP, Stinear TP.

PeerJ. 2017 Jan 24;5:e2916. doi: 10.7717/peerj.2916. eCollection 2017.


Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation.

Heilbronner S, Monk IR, Brozyna JR, Heinrichs DE, Skaar EP, Peschel A, Foster TJ.

PLoS Genet. 2016 Aug 30;12(8):e1006246. doi: 10.1371/journal.pgen.1006246. eCollection 2016 Aug. Erratum in: PLoS Genet. 2018 Jul 27;14(7):e1007564.


A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains.

Mairpady Shambat S, Siemens N, Monk IR, Mohan DB, Mukundan S, Krishnan KC, Prabhakara S, Snäll J, Kearns A, Vandenesch F, Svensson M, Kotb M, Gopal B, Arakere G, Norrby-Teglund A.

Sci Rep. 2016 Aug 11;6:31360. doi: 10.1038/srep31360.


De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In Vivo.

Kofoed EM, Yan D, Katakam AK, Reichelt M, Lin B, Kim J, Park S, Date SV, Monk IR, Xu M, Austin CD, Maurer T, Tan MW.

J Bacteriol. 2016 Jun 27;198(14):2001-2015. doi: 10.1128/JB.00051-16. Print 2016 Jul 15.


Erratum for Monk et al., Complete Bypass of Restriction Systems for Major Staphylococcus aureus Lineages.

Monk IR, Tree JJ, Howden BP, Stinear TP, Foster TJ.

MBio. 2016 Mar 1;7(2):e00171. doi: 10.1128/mBio.00171-16. No abstract available.


Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology.

Mairpady Shambat S, Chen P, Nguyen Hoang AT, Bergsten H, Vandenesch F, Siemens N, Lina G, Monk IR, Foster TJ, Arakere G, Svensson M, Norrby-Teglund A.

Dis Model Mech. 2015 Nov;8(11):1413-25. doi: 10.1242/dmm.021923. Epub 2015 Sep 3.


Fibronectin Binding Proteins SpsD and SpsL Both Support Invasion of Canine Epithelial Cells by Staphylococcus pseudintermedius.

Pietrocola G, Gianotti V, Richards A, Nobile G, Geoghegan JA, Rindi S, Monk IR, Bordt AS, Foster TJ, Fitzgerald JR, Speziale P.

Infect Immun. 2015 Oct;83(10):4093-102. doi: 10.1128/IAI.00542-15. Epub 2015 Aug 3.


Large tandem chromosome expansions facilitate niche adaptation during persistent infection with drug-resistant Staphylococcus aureus.

Gao W, Monk IR, Tobias NJ, Gladman SL, Seemann T, Stinear TP, Howden BP.

Microb Genom. 2015 Aug 3;1(2):e000026. doi: 10.1099/mgen.0.000026. eCollection 2015 Aug.


Manipulation of Autophagy in Phagocytes Facilitates Staphylococcus aureus Bloodstream Infection.

O'Keeffe KM, Wilk MM, Leech JM, Murphy AG, Laabei M, Monk IR, Massey RC, Lindsay JA, Foster TJ, Geoghegan JA, McLoughlin RM.

Infect Immun. 2015 Sep;83(9):3445-57. doi: 10.1128/IAI.00358-15. Epub 2015 Jun 22.


Complete Bypass of Restriction Systems for Major Staphylococcus aureus Lineages.

Monk IR, Tree JJ, Howden BP, Stinear TP, Foster TJ.

MBio. 2015 May 26;6(3):e00308-15. doi: 10.1128/mBio.00308-15. Erratum in: MBio. 2016;7(2):e00171.


Hyperexpression of α-hemolysin explains enhanced virulence of sequence type 93 community-associated methicillin-resistant Staphylococcus aureus.

Chua KY, Monk IR, Lin YH, Seemann T, Tuck KL, Porter JL, Stepnell J, Coombs GW, Davies JK, Stinear TP, Howden BP.

BMC Microbiol. 2014 Feb 10;14:31. doi: 10.1186/1471-2180-14-31.


The phage integrase vector pIPI03 allows RecA-independent, site-specific labelling of Staphylococcus lugdunensis strains.

Heilbronner S, Monk IR, Foster TJ.

Plasmid. 2013 Nov;70(3):377-84. doi: 10.1016/j.plasmid.2013.09.001. Epub 2013 Sep 13.


Sortase A promotes virulence in experimental Staphylococcus lugdunensis endocarditis.

Heilbronner S, Hanses F, Monk IR, Speziale P, Foster TJ.

Microbiology. 2013 Oct;159(Pt 10):2141-52. doi: 10.1099/mic.0.070292-0. Epub 2013 Aug 13.


Subdomains N2N3 of fibronectin binding protein A mediate Staphylococcus aureus biofilm formation and adherence to fibrinogen using distinct mechanisms.

Geoghegan JA, Monk IR, O'Gara JP, Foster TJ.

J Bacteriol. 2013 Jun;195(11):2675-83. doi: 10.1128/JB.02128-12. Epub 2013 Apr 5.


Nasal colonisation by Staphylococcus aureus depends upon clumping factor B binding to the squamous epithelial cell envelope protein loricrin.

Mulcahy ME, Geoghegan JA, Monk IR, O'Keeffe KM, Walsh EJ, Foster TJ, McLoughlin RM.

PLoS Pathog. 2012 Dec;8(12):e1003092. doi: 10.1371/journal.ppat.1003092. Epub 2012 Dec 27.


Genetic manipulation of Staphylococci-breaking through the barrier.

Monk IR, Foster TJ.

Front Cell Infect Microbiol. 2012 Apr 12;2:49. doi: 10.3389/fcimb.2012.00049. eCollection 2012. Review.


Transforming the untransformable: application of direct transformation to manipulate genetically Staphylococcus aureus and Staphylococcus epidermidis.

Monk IR, Shah IM, Xu M, Tan MW, Foster TJ.

MBio. 2012 Mar 20;3(2). pii: e00277-11. doi: 10.1128/mBio.00277-11. Print 2012.


A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy.

van Pijkeren JP, Morrissey D, Monk IR, Cronin M, Rajendran S, O'Sullivan GC, Gahan CG, Tangney M.

Hum Gene Ther. 2010 Apr;21(4):405-16. doi: 10.1089/hum.2009.022.


AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes.

Riedel CU, Monk IR, Casey PG, Waidmann MS, Gahan CG, Hill C.

Mol Microbiol. 2009 Mar;71(5):1177-89. doi: 10.1111/j.1365-2958.2008.06589.x. Epub 2009 Jan 19.


Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector.

Monk IR, Casey PG, Cronin M, Gahan CG, Hill C.

BMC Microbiol. 2008 Jun 13;8:96. doi: 10.1186/1471-2180-8-96.


Tools for functional postgenomic analysis of listeria monocytogenes.

Monk IR, Gahan CG, Hill C.

Appl Environ Microbiol. 2008 Jul;74(13):3921-34. doi: 10.1128/AEM.00314-08. Epub 2008 Apr 25.


Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro.

Riedel CU, Monk IR, Casey PG, Morrissey D, O'Sullivan GC, Tangney M, Hill C, Gahan CG.

Appl Environ Microbiol. 2007 May;73(9):3091-4. Epub 2007 Mar 9.


Morphotypic conversion in Listeria monocytogenes biofilm formation: biological significance of rough colony isolates.

Monk IR, Cook GM, Monk BC, Bremer PJ.

Appl Environ Microbiol. 2004 Nov;70(11):6686-94.

Supplemental Content

Support Center