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Items: 1 to 50 of 150

1.

Correction: mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development.

Molina L, Yang H, Michael AOA, Oertel M, Bell A, Singh S, Chen X, Tao J, Monga SP.

Oncotarget. 2019 Sep 24;10(54):5670. doi: 10.18632/oncotarget.27218. eCollection 2019 Sep 24.

2.

Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma.

Yarchoan M, Agarwal P, Villanueva A, Rao S, Dawson LA, Llovet JM, Finn RS, Groopman JD, El-Serag HB, Monga SP, Wang XW, Karin M, Schwartz RE, Tanabe KK, Roberts LR, Gunaratne PH, Tsung A, Brown KA, Lawrence TS, Salem R, Singal AG, Kim AK, Rabiee A, Resar L, Hoshida Y, He AR, Ghoshal K, Ryan PB, Jaffee EM, Guha C, Mishra L, Coleman CN, Ahmed MM.

Cancer Res. 2019 Sep 1;79(17):4326-4330. doi: 10.1158/0008-5472.CAN-19-0803.

PMID:
31481419
3.

Liver Progenitors and Adult Cell Plasticity in Hepatic Injury and Repair: Knowns and Unknowns.

Ko S, Russell JO, Molina LM, Monga SP.

Annu Rev Pathol. 2019 Aug 9. doi: 10.1146/annurev-pathmechdis-012419-032824. [Epub ahead of print]

PMID:
31399003
4.

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.

Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevilla C, Stärkel P, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R.

Nat Commun. 2019 Jul 16;10(1):3126. doi: 10.1038/s41467-019-11004-3.

5.

β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma.

Ruiz de Galarreta M, Bresnahan E, Molina-Sánchez P, Lindblad KE, Maier B, Sia D, Puigvehi M, Miguela V, Casanova-Acebes M, Dhainaut M, Villacorta-Martin C, Singhi AD, Moghe A, von Felden J, Tal Grinspan L, Wang S, Kamphorst AO, Monga SP, Brown BD, Villanueva A, Llovet JM, Merad M, Lujambio A.

Cancer Discov. 2019 Aug;9(8):1124-1141. doi: 10.1158/2159-8290.CD-19-0074. Epub 2019 Jun 11.

PMID:
31186238
6.

Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice.

Yan J, Tung HC, Li S, Niu Y, Garbacz WG, Lu P, Bi Y, Li Y, He J, Xu M, Ren S, Monga SP, Schwabe RF, Yang D, Xie W.

Gastroenterology. 2019 Sep;157(3):793-806.e14. doi: 10.1053/j.gastro.2019.05.066. Epub 2019 Jun 3.

PMID:
31170413
7.

Impaired Ribosomal Biogenesis by Noncanonical Degradation of β-Catenin during Hyperammonemia.

Davuluri G, Giusto M, Chandel R, Welch N, Alsabbagh K, Kant S, Kumar A, Kim A, Gangadhariah M, Ghosh PK, Tran U, Krajcik DM, Vasu K, DiDonato AJ, DiDonato JA, Willard B, Monga SP, Wang Y, Fox PL, Stark GR, Wessely O, Esser KA, Dasarathy S.

Mol Cell Biol. 2019 Jul 29;39(16). pii: e00451-18. doi: 10.1128/MCB.00451-18. Print 2019 Aug 15.

PMID:
31138664
8.

Notch Inhibition Promotes Differentiation of Liver Progenitor Cells into Hepatocytes via sox9b Repression in Zebrafish.

Russell JO, Ko S, Monga SP, Shin D.

Stem Cells Int. 2019 Mar 12;2019:8451282. doi: 10.1155/2019/8451282. eCollection 2019.

9.

Reply.

Chen X, Monga SP, Calvisi DF.

Hepatology. 2019 Aug;70(2):764-765. doi: 10.1002/hep.30644. No abstract available.

PMID:
30958900
10.

Dynamics and predicted drug response of a gene network linking dedifferentiation with beta-catenin dysfunction in hepatocellular carcinoma.

Gérard C, Di-Luoffo M, Gonay L, Caruso S, Couchy G, Loriot A, Castven D, Tao J, Konobrocka K, Cordi S, Monga SP, Hanert E, Marquardt JU, Zucman-Rossi J, Lemaigre FP.

J Hepatol. 2019 Aug;71(2):323-332. doi: 10.1016/j.jhep.2019.03.024. Epub 2019 Apr 4.

PMID:
30953666
11.

mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development.

Molina L, Yang H, Adebayo Michael AO, Oertel M, Bell A, Singh S, Chen X, Tao J, Monga SPS.

Oncotarget. 2019 Feb 19;10(15):1475-1490. doi: 10.18632/oncotarget.26668. eCollection 2019 Feb 19. Erratum in: Oncotarget. 2019 Sep 24;10(54):5670.

12.

β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis.

Min Q, Molina L, Li J, Adebayo Michael AO, Russell JO, Preziosi ME, Singh S, Poddar M, Matz-Soja M, Ranganathan S, Bell AW, Gebhardt R, Gaunitz F, Yu J, Tao J, Monga SP.

Am J Pathol. 2019 May;189(5):1091-1104. doi: 10.1016/j.ajpath.2019.02.002. Epub 2019 Feb 19. Erratum in: Am J Pathol. 2019 Aug;189(8):1680.

PMID:
30794807
13.

TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.

Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, Che L, Sumazin P, Ribback S, Kiss A, Schaff Z, Cigliano A, Dombrowski F, Cossu C, Pascale RM, Calvisi DF, Monga SP, Chen X.

Am J Pathol. 2019 May;189(5):1077-1090. doi: 10.1016/j.ajpath.2019.01.016. Epub 2019 Feb 19.

PMID:
30794805
14.

Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice.

Qiao Y, Wang J, Karagoz E, Liang B, Song X, Shang R, Evert K, Xu M, Che L, Evert M, Calvisi DF, Tao J, Wang B, Monga SP, Chen X.

Hepatology. 2019 Feb 8. doi: 10.1002/hep.30556. [Epub ahead of print]

PMID:
30737831
15.

Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.

Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell JO, Pradhan-Sundd T, Liu S, Singh S, Poddar M, Monga JS, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen X, Monga SP.

Cell Metab. 2019 May 7;29(5):1135-1150.e6. doi: 10.1016/j.cmet.2019.01.002. Epub 2019 Jan 31.

PMID:
30713111
16.

Blood-Bile Barrier: Morphology, Regulation, and Pathophysiology.

Pradhan-Sundd T, Monga SP.

Gene Expr. 2019 Apr 18;19(2):69-87. doi: 10.3727/105221619X15469715711907. Epub 2019 Jan 15.

17.

Loss of Wnt Secretion by Macrophages Promotes Hepatobiliary Injury after Administration of 3,5-Diethoxycarbonyl-1, 4-Dihydrocollidine Diet.

Jiang A, Okabe H, Popovic B, Preziosi ME, Pradhan-Sundd T, Poddar M, Singh S, Bell A, England SG, Nagarajan S, Monga SP.

Am J Pathol. 2019 Mar;189(3):590-603. doi: 10.1016/j.ajpath.2018.11.010. Epub 2019 Jan 2.

18.

Updates on hepatic homeostasis and the many tiers of hepatobiliary repair.

Monga SP.

Nat Rev Gastroenterol Hepatol. 2019 Feb;16(2):84-86. doi: 10.1038/s41575-018-0090-x. Review. No abstract available.

PMID:
30531815
19.

Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice.

Qiao Y, Xu M, Tao J, Che L, Cigliano A, Monga SP, Calvisi DF, Chen X.

BMC Cancer. 2018 Nov 12;18(1):1093. doi: 10.1186/s12885-018-4870-z.

20.

Loss of hepatocyte β-catenin protects mice from experimental porphyria-associated liver injury.

Saggi H, Maitra D, Jiang A, Zhang R, Wang P, Cornuet P, Singh S, Locker J, Ma X, Dailey H, Abrams M, Omary MB, Monga SP, Nejak-Bowen K.

J Hepatol. 2019 Jan;70(1):108-117. doi: 10.1016/j.jhep.2018.09.023. Epub 2018 Oct 1.

PMID:
30287339
21.

Hdac1 Regulates Differentiation of Bipotent Liver Progenitor Cells During Regeneration via Sox9b and Cdk8.

Ko S, Russell JO, Tian J, Gao C, Kobayashi M, Feng R, Yuan X, Shao C, Ding H, Poddar M, Singh S, Locker J, Weng HL, Monga SP, Shin D.

Gastroenterology. 2019 Jan;156(1):187-202.e14. doi: 10.1053/j.gastro.2018.09.039. Epub 2018 Sep 26.

PMID:
30267710
22.

Elimination of Wnt Secretion From Stellate Cells Is Dispensable for Zonation and Development of Liver Fibrosis Following Hepatobiliary Injury.

Zhang R, Kikuchi AT, Nakao T, Russell JO, Preziosi ME, Poddar M, Singh S, Bell AW, England SG, Monga SP.

Gene Expr. 2019 Apr 18;19(2):121-136. doi: 10.3727/105221618X15373858350141. Epub 2018 Sep 20.

23.

Hepatocyte-Specific β-Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes.

Russell JO, Lu WY, Okabe H, Abrams M, Oertel M, Poddar M, Singh S, Forbes SJ, Monga SP.

Hepatology. 2019 Feb;69(2):742-759. doi: 10.1002/hep.30270. Epub 2019 Jan 4.

24.

High Frequency of β-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist.

Mattu S, Saliba C, Sulas P, Zavattari P, Perra A, Kowalik MA, Monga SP, Columbano A.

Am J Pathol. 2018 Nov;188(11):2497-2507. doi: 10.1016/j.ajpath.2018.07.022. Epub 2018 Sep 8.

PMID:
30201494
25.

Hepatic Zonation Now on Hormones!

Ko S, Monga SP.

Hepatology. 2019 Mar;69(3):1339-1342. doi: 10.1002/hep.30221. Epub 2019 Feb 7. No abstract available.

PMID:
30120897
26.

Endothelial Wnts regulate β-catenin signaling in murine liver zonation and regeneration: A sequel to the Wnt-Wnt situation.

Preziosi M, Okabe H, Poddar M, Singh S, Monga SP.

Hepatol Commun. 2018 Jun 21;2(7):845-860. doi: 10.1002/hep4.1196. eCollection 2018 Jul.

27.

Dysregulated Bile Transporters and Impaired Tight Junctions During Chronic Liver Injury in Mice.

Pradhan-Sundd T, Vats R, Russell JO, Singh S, Michael AA, Molina L, Kakar S, Cornuet P, Poddar M, Watkins SC, Nejak-Bowen KN, Monga SP, Sundd P.

Gastroenterology. 2018 Oct;155(4):1218-1232.e24. doi: 10.1053/j.gastro.2018.06.048. Epub 2018 Jun 30.

28.

Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma.

Molina L, Bell D, Tao J, Preziosi M, Pradhan-Sundd T, Singh S, Poddar M, Luo J, Ranganathan S, Chikina M, Monga SP.

Am J Pathol. 2018 Aug;188(8):1895-1909. doi: 10.1016/j.ajpath.2018.05.006. Epub 2018 Jun 18.

29.

Novel Genetic Activation Screening in Liver Repopulation and Cancer: Now CRISPR Than Ever!

Preziosi M, Monga SP.

Hepatology. 2018 Aug;68(2):408-411. doi: 10.1002/hep.30084. No abstract available.

30.

Identification of a unique loss-of-function mutation in IGF1R and a crosstalk between IGF1R and Wnt/β-catenin signaling pathways.

Jamwal G, Singh G, Dar MS, Singh P, Bano N, Syed SH, Sandhu P, Akhter Y, Monga SP, Dar MJ.

Biochim Biophys Acta Mol Cell Res. 2018 Jun;1865(6):920-931. doi: 10.1016/j.bbamcr.2018.03.013. Epub 2018 Apr 3.

31.

Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration.

Russell JO, Ko S, Saggi HS, Singh S, Poddar M, Shin D, Monga SP.

Am J Pathol. 2018 Jun;188(6):1389-1405. doi: 10.1016/j.ajpath.2018.02.006. Epub 2018 Mar 12.

32.

Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer.

Preziosi M, Poddar M, Singh S, Monga SP.

Gene Expr. 2018 Aug 22;18(3):209-219. doi: 10.3727/105221618X15205148413587. Epub 2018 Mar 8.

33.

The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, β-Catenin-Mutated Mouse Model.

Zhan N, Michael AA, Wu K, Zeng G, Bell A, Tao J, Monga SP.

Gene Expr. 2018 May 18;18(2):135-147. doi: 10.3727/105221618X15174108894682. Epub 2018 Feb 6.

34.

Lipid metabolic reprogramming in hepatic ischemia-reperfusion injury.

Monga SP.

Nat Med. 2018 Jan 9;24(1):6-7. doi: 10.1038/nm.4468. No abstract available.

PMID:
29315298
35.

Wnt/β-Catenin Signaling in Liver Development, Homeostasis, and Pathobiology.

Russell JO, Monga SP.

Annu Rev Pathol. 2018 Jan 24;13:351-378. doi: 10.1146/annurev-pathol-020117-044010. Epub 2017 Nov 10. Review.

36.

Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis.

Pradhan-Sundd T, Zhou L, Vats R, Jiang A, Molina L, Singh S, Poddar M, Russell J, Stolz DB, Oertel M, Apte U, Watkins S, Ranganathan S, Nejak-Bowen KN, Sundd P, Monga SP.

Hepatology. 2018 Jun;67(6):2320-2337. doi: 10.1002/hep.29585. Epub 2018 Apr 19.

37.

Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma.

Liu C, Ren YF, Dong J, Ke MY, Ma F, Monga SPS, Wu R, Lv Y, Zhang XF.

Cancer Lett. 2017 Dec 1;410:20-31. doi: 10.1016/j.canlet.2017.09.013. Epub 2017 Sep 21.

PMID:
28942012
38.

Thyroid Hormone Receptor-β Agonist GC-1 Inhibits Met-β-Catenin-Driven Hepatocellular Cancer.

Puliga E, Min Q, Tao J, Zhang R, Pradhan-Sundd T, Poddar M, Singh S, Columbano A, Yu J, Monga SP.

Am J Pathol. 2017 Nov;187(11):2473-2485. doi: 10.1016/j.ajpath.2017.07.005. Epub 2017 Aug 12.

39.

Platelet-Derived Growth Factor Receptor α Contributes to Human Hepatic Stellate Cell Proliferation and Migration.

Kikuchi A, Pradhan-Sundd T, Singh S, Nagarajan S, Loizos N, Monga SP.

Am J Pathol. 2017 Oct;187(10):2273-2287. doi: 10.1016/j.ajpath.2017.06.009. Epub 2017 Jul 20.

40.

β-Catenin regulation of farnesoid X receptor signaling and bile acid metabolism during murine cholestasis.

Thompson MD, Moghe A, Cornuet P, Marino R, Tian J, Wang P, Ma X, Abrams M, Locker J, Monga SP, Nejak-Bowen K.

Hepatology. 2018 Mar;67(3):955-971. doi: 10.1002/hep.29371. Epub 2018 Jan 26.

41.

Update on the Mechanisms of Liver Regeneration.

Preziosi ME, Monga SP.

Semin Liver Dis. 2017 May;37(2):141-151. doi: 10.1055/s-0037-1601351. Epub 2017 May 31. Review.

42.

Role and Regulation of p65/β-Catenin Association During Liver Injury and Regeneration: A "Complex" Relationship.

Nejak-Bowen K, Moghe A, Cornuet P, Preziosi M, Nagarajan S, Monga SP.

Gene Expr. 2017 Jul 7;17(3):219-235. doi: 10.3727/105221617X695762. Epub 2017 Apr 28.

43.

Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.

Soto-Gutierrez A, Gough A, Vernetti LA, Taylor DL, Monga SP.

Exp Biol Med (Maywood). 2017 Oct;242(16):1605-1616. doi: 10.1177/1535370217707731. Epub 2017 May 3. Review.

44.

Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload.

Preziosi ME, Singh S, Valore EV, Jung G, Popovic B, Poddar M, Nagarajan S, Ganz T, Monga SP.

J Hepatol. 2017 Aug;67(2):360-369. doi: 10.1016/j.jhep.2017.03.012. Epub 2017 Mar 22.

45.

MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice.

Chen ZH, Yu YP, Tao J, Liu S, Tseng G, Nalesnik M, Hamilton R, Bhargava R, Nelson JB, Pennathur A, Monga SP, Luketich JD, Michalopoulos GK, Luo JH.

Gastroenterology. 2017 Oct;153(4):1120-1132.e15. doi: 10.1053/j.gastro.2016.12.036. Epub 2017 Feb 27.

46.

Targeting β-catenin in hepatocellular cancers induced by coexpression of mutant β-catenin and K-Ras in mice.

Tao J, Zhang R, Singh S, Poddar M, Xu E, Oertel M, Chen X, Ganesh S, Abrams M, Monga SP.

Hepatology. 2017 May;65(5):1581-1599. doi: 10.1002/hep.28975. Epub 2017 Feb 6.

47.

Novel Advances in Understanding of Molecular Pathogenesis of Hepatoblastoma: A Wnt/β-Catenin Perspective.

Bell D, Ranganathan S, Tao J, Monga SP.

Gene Expr. 2017 Feb 10;17(2):141-154. doi: 10.3727/105221616X693639. Epub 2016 Nov 2. Review.

48.

Wnt signaling regulates hepatobiliary repair following cholestatic liver injury in mice.

Okabe H, Yang J, Sylakowski K, Yovchev M, Miyagawa Y, Nagarajan S, Chikina M, Thompson M, Oertel M, Baba H, Monga SP, Nejak-Bowen KN.

Hepatology. 2016 Nov;64(5):1652-1666. doi: 10.1002/hep.28774. Epub 2016 Sep 26.

49.

Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant β-catenin.

Tao J, Xu E, Zhao Y, Singh S, Li X, Couchy G, Chen X, Zucman-Rossi J, Chikina M, Monga SP.

Hepatology. 2016 Nov;64(5):1587-1605. doi: 10.1002/hep.28601. Epub 2016 May 28.

50.

Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma.

Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV.

J Biol Chem. 2016 Dec 16;291(51):26241-26251. Epub 2016 Oct 13.

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