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Items: 1 to 50 of 125

1.

Endothelial Wnts regulate β-catenin signaling in murine liver zonation and regeneration: A sequel to the Wnt-Wnt situation.

Preziosi M, Okabe H, Poddar M, Singh S, Monga SP.

Hepatol Commun. 2018 Jun 21;2(7):845-860. doi: 10.1002/hep4.1196. eCollection 2018 Jul.

2.

Dysregulated bile transporters and impaired tight junctions during chronic liver injury in mice.

Pradhan-Sundd T, Vats R, Russell JM, Singh S, Michael AA, Molina L, Kakar S, Cornuet P, Poddar M, Watkins SC, Nejak-Bowen KN, Monga SP, Sundd P.

Gastroenterology. 2018 Jun 28. pii: S0016-5085(18)34690-0. doi: 10.1053/j.gastro.2018.06.048. [Epub ahead of print]

PMID:
29964040
3.

Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma.

Molina L, Bell D, Tao J, Preziosi M, Pradhan-Sundd T, Singh S, Poddar M, Luo J, Ranganathan S, Chikina M, Monga SP.

Am J Pathol. 2018 Aug;188(8):1895-1909. doi: 10.1016/j.ajpath.2018.05.006. Epub 2018 Jun 18.

PMID:
29920228
4.

Novel genetic activation screening in liver repopulation and cancer; Now crispr than ever!

Preziosi M, Monga SP.

Hepatology. 2018 May 9. doi: 10.1002/hep.30084. [Epub ahead of print] No abstract available.

PMID:
29742805
5.

Identification of a unique loss-of-function mutation in IGF1R and a crosstalk between IGF1R and Wnt/β-catenin signaling pathways.

Jamwal G, Singh G, Dar MS, Singh P, Bano N, Syed SH, Sandhu P, Akhter Y, Monga SP, Dar MJ.

Biochim Biophys Acta. 2018 Jun;1865(6):920-931. doi: 10.1016/j.bbamcr.2018.03.013. Epub 2018 Apr 3.

PMID:
29621572
6.

Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration.

Russell JO, Ko S, Saggi HS, Singh S, Poddar M, Shin D, Monga SP.

Am J Pathol. 2018 Jun;188(6):1389-1405. doi: 10.1016/j.ajpath.2018.02.006. Epub 2018 Mar 12.

PMID:
29545201
7.

Hepatocyte Wnts are dispensable during diethylnitrosamine and carbon tetrachloride-induced injury and hepatocellular cancer.

Preziosi M, Poddar M, Singh S, Monga SP.

Gene Expr. 2018 Mar 8. doi: 10.3727/105221618X15205148413587. [Epub ahead of print]

PMID:
29519268
8.

The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, β-Catenin-Mutated Mouse Model.

Zhan N, Michael AA, Wu K, Zeng G, Bell A, Tao J, Monga SP.

Gene Expr. 2018 May 18;18(2):135-147. doi: 10.3727/105221618X15174108894682. Epub 2018 Feb 6.

9.

Lipid metabolic reprogramming in hepatic ischemia-reperfusion injury.

Monga SP.

Nat Med. 2018 Jan 9;24(1):6-7. doi: 10.1038/nm.4468. No abstract available.

PMID:
29315298
10.

Wnt/β-Catenin Signaling in Liver Development, Homeostasis, and Pathobiology.

Russell JO, Monga SP.

Annu Rev Pathol. 2018 Jan 24;13:351-378. doi: 10.1146/annurev-pathol-020117-044010. Epub 2017 Nov 10.

11.

Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis.

Pradhan-Sundd T, Zhou L, Vats R, Jiang A, Molina L, Singh S, Poddar M, Russell J, Stolz DB, Oertel M, Apte U, Watkins S, Ranganathan S, Nejak-Bowen KN, Sundd P, Monga SP.

Hepatology. 2018 Jun;67(6):2320-2337. doi: 10.1002/hep.29585. Epub 2018 Apr 19.

PMID:
29023813
12.

Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma.

Liu C, Ren YF, Dong J, Ke MY, Ma F, Monga SPS, Wu R, Lv Y, Zhang XF.

Cancer Lett. 2017 Dec 1;410:20-31. doi: 10.1016/j.canlet.2017.09.013. Epub 2017 Sep 21.

PMID:
28942012
13.

Thyroid Hormone Receptor-β Agonist GC-1 Inhibits Met-β-Catenin-Driven Hepatocellular Cancer.

Puliga E, Min Q, Tao J, Zhang R, Pradhan-Sundd T, Poddar M, Singh S, Columbano A, Yu J, Monga SP.

Am J Pathol. 2017 Nov;187(11):2473-2485. doi: 10.1016/j.ajpath.2017.07.005. Epub 2017 Aug 12.

PMID:
28807594
14.

Platelet-Derived Growth Factor Receptor α Contributes to Human Hepatic Stellate Cell Proliferation and Migration.

Kikuchi A, Pradhan-Sundd T, Singh S, Nagarajan S, Loizos N, Monga SP.

Am J Pathol. 2017 Oct;187(10):2273-2287. doi: 10.1016/j.ajpath.2017.06.009. Epub 2017 Jul 20.

PMID:
28734947
15.

β-Catenin regulation of farnesoid X receptor signaling and bile acid metabolism during murine cholestasis.

Thompson MD, Moghe A, Cornuet P, Marino R, Tian J, Wang P, Ma X, Abrams M, Locker J, Monga SP, Nejak-Bowen K.

Hepatology. 2018 Mar;67(3):955-971. doi: 10.1002/hep.29371. Epub 2018 Jan 26.

PMID:
28714273
16.

Update on the Mechanisms of Liver Regeneration.

Preziosi ME, Monga SP.

Semin Liver Dis. 2017 May;37(2):141-151. doi: 10.1055/s-0037-1601351. Epub 2017 May 31. Review.

17.

Role and Regulation of p65/β-Catenin Association During Liver Injury and Regeneration: A "Complex" Relationship.

Nejak-Bowen K, Moghe A, Cornuet P, Preziosi M, Nagarajan S, Monga SP.

Gene Expr. 2017 Jul 7;17(3):219-235. doi: 10.3727/105221617X695762. Epub 2017 Apr 28.

18.

Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems.

Soto-Gutierrez A, Gough A, Vernetti LA, Taylor DL, Monga SP.

Exp Biol Med (Maywood). 2017 Oct;242(16):1605-1616. doi: 10.1177/1535370217707731. Epub 2017 May 3. Review.

19.

Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload.

Preziosi ME, Singh S, Valore EV, Jung G, Popovic B, Poddar M, Nagarajan S, Ganz T, Monga SP.

J Hepatol. 2017 Aug;67(2):360-369. doi: 10.1016/j.jhep.2017.03.012. Epub 2017 Mar 22.

20.

MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice.

Chen ZH, Yu YP, Tao J, Liu S, Tseng G, Nalesnik M, Hamilton R, Bhargava R, Nelson JB, Pennathur A, Monga SP, Luketich JD, Michalopoulos GK, Luo JH.

Gastroenterology. 2017 Oct;153(4):1120-1132.e15. doi: 10.1053/j.gastro.2016.12.036. Epub 2017 Feb 27.

PMID:
28245430
21.

Targeting β-catenin in hepatocellular cancers induced by coexpression of mutant β-catenin and K-Ras in mice.

Tao J, Zhang R, Singh S, Poddar M, Xu E, Oertel M, Chen X, Ganesh S, Abrams M, Monga SP.

Hepatology. 2017 May;65(5):1581-1599. doi: 10.1002/hep.28975. Epub 2017 Feb 6.

22.

Novel Advances in Understanding of Molecular Pathogenesis of Hepatoblastoma: A Wnt/β-Catenin Perspective.

Bell D, Ranganathan S, Tao J, Monga SP.

Gene Expr. 2017 Feb 10;17(2):141-154. doi: 10.3727/105221616X693639. Epub 2016 Nov 2. Review.

23.

Wnt signaling regulates hepatobiliary repair following cholestatic liver injury in mice.

Okabe H, Yang J, Sylakowski K, Yovchev M, Miyagawa Y, Nagarajan S, Chikina M, Thompson M, Oertel M, Baba H, Monga SP, Nejak-Bowen KN.

Hepatology. 2016 Nov;64(5):1652-1666. doi: 10.1002/hep.28774. Epub 2016 Sep 26.

24.

Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant β-catenin.

Tao J, Xu E, Zhao Y, Singh S, Li X, Couchy G, Chen X, Zucman-Rossi J, Chikina M, Monga SP.

Hepatology. 2016 Nov;64(5):1587-1605. doi: 10.1002/hep.28601. Epub 2016 May 28.

25.

Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma.

Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV.

J Biol Chem. 2016 Dec 16;291(51):26241-26251. Epub 2016 Oct 13.

26.

Editorial.

Monga SP, Jacob S.

Gene Expr. 2016;17(1):1-5. doi: 10.3727/105221616X692595. No abstract available.

PMID:
27678082
27.

Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin.

Ganesh S, Koser ML, Cyr WA, Chopda GR, Tao J, Shui X, Ying B, Chen D, Pandya P, Chipumuro E, Siddiquee Z, Craig K, Lai C, Dudek H, Monga SP, Wang W, Brown BD, Abrams MT.

Mol Cancer Ther. 2016 Sep;15(9):2143-54. doi: 10.1158/1535-7163.MCT-16-0309. Epub 2016 Jul 7.

28.

Terminal regions of β-catenin are critical for regulating its adhesion and transcription functions.

Dar MS, Singh P, Singh G, Jamwal G, Hussain SS, Rana A, Akhter Y, Monga SP, Dar MJ.

Biochim Biophys Acta. 2016 Sep;1863(9):2345-57. doi: 10.1016/j.bbamcr.2016.06.010. Epub 2016 Jun 29.

29.

Thyroid Hormone Receptor β Agonist Induces β-Catenin-Dependent Hepatocyte Proliferation in Mice: Implications in Hepatic Regeneration.

Alvarado TF, Puliga E, Preziosi M, Poddar M, Singh S, Columbano A, Nejak-Bowen K, Monga SP.

Gene Expr. 2016;17(1):19-34. doi: 10.3727/105221616X691631. Epub 2016 May 24.

30.

Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes.

Edmunds LR, Otero PA, Sharma L, D'Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck ME, Vockley J, Monga SP, Kershaw EE, O'Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV.

Oncotarget. 2016 May 24;7(21):30379-95. doi: 10.18632/oncotarget.8856.

31.

Diverse Basis of β-Catenin Activation in Human Hepatocellular Carcinoma: Implications in Biology and Prognosis.

Okabe H, Kinoshita H, Imai K, Nakagawa S, Higashi T, Arima K, Uchiyama H, Ikegami T, Harimoto N, Itoh S, Ishiko T, Yoshizumi T, Beppu T, Monga SP, Baba H, Maehara Y.

PLoS One. 2016 Apr 21;11(4):e0152695. doi: 10.1371/journal.pone.0152695. eCollection 2016.

32.

Role of β-catenin in development of bile ducts.

Cordi S, Godard C, Saandi T, Jacquemin P, Monga SP, Colnot S, Lemaigre FP.

Differentiation. 2016 Jan-Mar;91(1-3):42-9. doi: 10.1016/j.diff.2016.02.001. Epub 2016 Feb 5.

33.

Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration.

Huang J, Schriefer AE, Cliften PF, Dietzen D, Kulkarni S, Sing S, Monga SP, Rudnick DA.

Am J Pathol. 2016 Mar;186(3):587-99. doi: 10.1016/j.ajpath.2015.10.027. Epub 2016 Jan 6.

34.

Muc1 enhances the β-catenin protective pathway during ischemia-reperfusion injury.

Al-Bataineh MM, Kinlough CL, Poland PA, Pastor-Soler NM, Sutton TA, Mang HE, Bastacky SI, Gendler SJ, Madsen CS, Singh S, Monga SP, Hughey RP.

Am J Physiol Renal Physiol. 2016 Mar 15;310(6):F569-79. doi: 10.1152/ajprenal.00520.2015. Epub 2016 Jan 6.

35.

Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration.

Ko S, Choi TY, Russell JO, So J, Monga SPS, Shin D.

J Hepatol. 2016 Feb;64(2):316-325. doi: 10.1016/j.jhep.2015.10.017. Epub 2015 Oct 24.

36.

Mice with Hepatic Loss of the Desmosomal Protein γ-Catenin Are Prone to Cholestatic Injury and Chemical Carcinogenesis.

Zhou L, Pradhan-Sundd T, Poddar M, Singh S, Kikuchi A, Stolz DB, Shou W, Li Z, Nejak-Bowen KN, Monga SP.

Am J Pathol. 2015 Dec;185(12):3274-89. doi: 10.1016/j.ajpath.2015.08.019. Epub 2015 Oct 17.

37.

Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs.

Eisses JF, Criscimanna A, Dionise ZR, Orabi AI, Javed TA, Sarwar S, Jin S, Zhou L, Singh S, Poddar M, Davis AW, Tosun AB, Ozolek JA, Lowe ME, Monga SP, Rohde GK, Esni F, Husain SZ.

Am J Pathol. 2015 Dec;185(12):3304-15. doi: 10.1016/j.ajpath.2015.08.006. Epub 2015 Oct 23.

38.

ADAR1 Prevents Liver Injury from Inflammation and Suppresses Interferon Production in Hepatocytes.

Wang G, Wang H, Singh S, Zhou P, Yang S, Wang Y, Zhu Z, Zhang J, Chen A, Billiar T, Monga SP, Wang Q.

Am J Pathol. 2015 Dec;185(12):3224-37. doi: 10.1016/j.ajpath.2015.08.002. Epub 2015 Oct 9.

39.

WNT5A inhibits hepatocyte proliferation and concludes β-catenin signaling in liver regeneration.

Yang J, Cusimano A, Monga JK, Preziosi ME, Pullara F, Calero G, Lang R, Yamaguchi TP, Nejak-Bowen KN, Monga SP.

Am J Pathol. 2015 Aug;185(8):2194-205. doi: 10.1016/j.ajpath.2015.04.021. Epub 2015 Jun 19.

40.

Muc1 is protective during kidney ischemia-reperfusion injury.

Pastor-Soler NM, Sutton TA, Mang HE, Kinlough CL, Gendler SJ, Madsen CS, Bastacky SI, Ho J, Al-Bataineh MM, Hallows KR, Singh S, Monga SP, Kobayashi H, Haase VH, Hughey RP.

Am J Physiol Renal Physiol. 2015 Jun 15;308(12):F1452-62. doi: 10.1152/ajprenal.00066.2015. Epub 2015 Apr 29.

41.

β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis.

Monga SP.

Gastroenterology. 2015 Jun;148(7):1294-310. doi: 10.1053/j.gastro.2015.02.056. Epub 2015 Mar 5. Review.

42.

PDGFRα in liver pathophysiology: emerging roles in development, regeneration, fibrosis, and cancer.

Kikuchi A, Monga SP.

Gene Expr. 2015;16(3):109-27. doi: 10.3727/105221615X14181438356210. Review.

43.

Complete response of Ctnnb1-mutated tumours to β-catenin suppression by locked nucleic acid antisense in a mouse hepatocarcinogenesis model.

Delgado E, Okabe H, Preziosi M, Russell JO, Alvarado TF, Oertel M, Nejak-Bowen KN, Zhang Y, Monga SP.

J Hepatol. 2015 Feb;62(2):380-7. doi: 10.1016/j.jhep.2014.10.021. Epub 2014 Oct 18.

44.

Pro-regenerative signaling after acetaminophen-induced acute liver injury in mice identified using a novel incremental dose model.

Bhushan B, Walesky C, Manley M, Gallagher T, Borude P, Edwards G, Monga SP, Apte U.

Am J Pathol. 2014 Nov;184(11):3013-25. doi: 10.1016/j.ajpath.2014.07.019. Epub 2014 Sep 2.

45.

Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma.

Okabe H, Delgado E, Lee JM, Yang J, Kinoshita H, Hayashi H, Tsung A, Behari J, Beppu T, Baba H, Monga SP.

PLoS One. 2014 Jun 3;9(6):e98817. doi: 10.1371/journal.pone.0098817. eCollection 2014.

46.

Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.

Tao J, Calvisi DF, Ranganathan S, Cigliano A, Zhou L, Singh S, Jiang L, Fan B, Terracciano L, Armeanu-Ebinger S, Ribback S, Dombrowski F, Evert M, Chen X, Monga SPS.

Gastroenterology. 2014 Sep;147(3):690-701. doi: 10.1053/j.gastro.2014.05.004. Epub 2014 May 14.

47.

Identification and characterization of a novel small-molecule inhibitor of β-catenin signaling.

Delgado ER, Yang J, So J, Leimgruber S, Kahn M, Ishitani T, Shin D, Mustata Wilson G, Monga SP.

Am J Pathol. 2014 Jul;184(7):2111-22. doi: 10.1016/j.ajpath.2014.04.002. Epub 2014 May 10.

48.

Role and regulation of β-catenin signaling during physiological liver growth.

Monga SP.

Gene Expr. 2014;16(2):51-62. doi: 10.3727/105221614X13919976902138. Review.

49.

β-catenin signaling in murine liver zonation and regeneration: a Wnt-Wnt situation!

Yang J, Mowry LE, Nejak-Bowen KN, Okabe H, Diegel CR, Lang RA, Williams BO, Monga SP.

Hepatology. 2014 Sep;60(3):964-76. doi: 10.1002/hep.27082. Epub 2014 Jul 25.

50.

Hepatic regenerative medicine: exploiting the liver's will to live.

Monga SP.

Am J Pathol. 2014 Feb;184(2):306-8. doi: 10.1016/j.ajpath.2013.11.004.

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