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Switching from efavirenz to rilpivirine improves sleep quality and self-perceived cognition but has no impact on neurocognitive performances: Results from a randomized controlled trial.

Lapadula G, Bernasconi DP, Bai F, Focà E, Di Biagio A, Bonora S, Castelli F, Squillace N, Bandera A, Monforte AD, Migliorino GM, Gori A; SWEAR Study Group.

AIDS. 2019 Sep 26. doi: 10.1097/QAD.0000000000002377. [Epub ahead of print]


Serious clinical events in HIV-positive persons with chronic kidney disease (CKD).

Ryom L, Lundgren JD, Law M, Kirk O, El-Sadr W, Bonnet F, Weber R, Fontas E, Monforte AD, Phillips A, Reiss P, de Wit S, Hatleberg CI, Sabin C, Mocroft A; D:A:D study group.

AIDS. 2019 Aug 2. doi: 10.1097/QAD.0000000000002331. [Epub ahead of print]


Impact of Phenolic Compounds in Strecker Aldehyde Formation in Wine Model Systems: Target and Untargeted Analysis.

Monforte AR, Martins SIFS, Silva Ferreira AC.

J Agric Food Chem. 2019 Jul 12. doi: 10.1021/acs.jafc.9b02674. [Epub ahead of print]


Re-evaluation of the role of Indian germplasm as center of melon diversification based on genotyping-by-sequencing analysis.

Gonzalo MJ, Díaz A, Dhillon NPS, Reddy UK, Picó B, Monforte AJ.

BMC Genomics. 2019 Jun 3;20(1):448. doi: 10.1186/s12864-019-5784-0.


Simulated human digestion of N1-aryl-2-arylthioacetamidobenzimidazoles and their activity against Herpes-simplex virus 1 in vitro.

Mandalari G, Bisignano C, Smeriglio A, Denaro M, Musarra-Pizzo M, Pennisi R, Mancuso F, Ferro S, Trombetta D, Monforte AM, Sciortino MT, De Luca L.

PLoS One. 2019 May 2;14(5):e0216384. doi: 10.1371/journal.pone.0216384. eCollection 2019.


Very high pre-therapy viral load is a predictor of virological rebound in HIV-1-infected patients starting a modern first-line regimen.

Armenia D, Di Carlo D, Cozzi-Lepri A, Calcagno A, Borghi V, Gori C, Bertoli A, Gennari W, Bellagamba R, Castagna A, Latini A, Pinnetti C, Cicalini S, Saracino A, Lapadula G, Rusconi S, Castelli F, Di Giambenedetto S, Andreoni M, Di Perri G, Antinori A, Mussini C, Ceccherini-Silberstein F, Monforte AD, Perno CF, Santoro MM; ICONA Foundation Study Group.

Antivir Ther. 2019 Apr 12. doi: 10.3851/IMP3309. [Epub ahead of print]


Response surface methodology: A tool to minimize aldehydes formation and oxygen consumption in wine model system.

Monforte AR, Oliveira C, Martins SIFS, Silva Ferreira AC.

Food Chem. 2019 Jun 15;283:559-565. doi: 10.1016/j.foodchem.2019.01.063. Epub 2019 Jan 18.


A common genetic mechanism underlies morphological diversity in fruits and other plant organs.

Wu S, Zhang B, Keyhaninejad N, Rodríguez GR, Kim HJ, Chakrabarti M, Illa-Berenguer E, Taitano NK, Gonzalo MJ, Díaz A, Pan Y, Leisner CP, Halterman D, Buell CR, Weng Y, Jansky SH, van Eck H, Willemsen J, Monforte AJ, Meulia T, van der Knaap E.

Nat Commun. 2018 Nov 9;9(1):4734. doi: 10.1038/s41467-018-07216-8.


Repeated domestication of melon (Cucumis melo) in Africa and Asia and a new close relative from India.

Endl J, Achigan-Dako EG, Pandey AK, Monforte AJ, Pico B, Schaefer H.

Am J Bot. 2018 Oct;105(10):1662-1671. doi: 10.1002/ajb2.1172. Epub 2018 Oct 9.


Graphene Quantum Dots Based Systems As HIV Inhibitors.

Iannazzo D, Pistone A, Ferro S, De Luca L, Monforte AM, Romeo R, Buemi MR, Pannecouque C.

Bioconjug Chem. 2018 Sep 19;29(9):3084-3093. doi: 10.1021/acs.bioconjchem.8b00448. Epub 2018 Aug 22.


Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis.

De Luca L, Ferro S, Buemi MR, Monforte AM, Gitto R, Schirmeister T, Maes L, Rescifina A, Micale N.

Chem Biol Drug Des. 2018 Sep;92(3):1585-1596. doi: 10.1111/cbdd.13326. Epub 2018 May 31.


Immune activation, inflammation and HIV DNA after 96 weeks of ATV/r monotherapy: a MODAt substudy.

Merlini E, Galli L, Tincati C, Cannizzo ES, Galli A, Gianotti N, Ancona G, Muccini C, Monforte AD, Marchetti G, Castagna A; MODAt study group.

Antivir Ther. 2018;23(7):633-637. doi: 10.3851/IMP3234. No abstract available.


Increased non-AIDS mortality among persons with AIDS-defining events after antiretroviral therapy initiation.

Pettit AC, Giganti MJ, Ingle SM, May MT, Shepherd BE, Gill MJ, Fätkenheuer G, Abgrall S, Saag MS, Del Amo J, Justice AC, Miro JM, Cavasinni M, Dabis F, Monforte AD, Reiss P, Guest J, Moore D, Shepherd L, Obel N, Crane HM, Smith C, Teira R, Zangerle R, Sterne JA, Sterling TR; Antiretroviral Therapy Cohort Collaboration (ART-CC) investigators.

J Int AIDS Soc. 2018 Jan;21(1). doi: 10.1002/jia2.25031.


Structural optimization of N1-aryl-benzimidazoles for the discovery of new non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains.

Monforte AM, De Luca L, Buemi MR, Agharbaoui FE, Pannecouque C, Ferro S.

Bioorg Med Chem. 2018 Feb 1;26(3):661-674. doi: 10.1016/j.bmc.2017.12.033. Epub 2017 Dec 24.


Differences in Virological and Immunological Risk Factors for Non-Hodgkin and Hodgkin Lymphoma.

Shepherd L, Ryom L, Law M, Hatleberg CI, de Wit S, Monforte AD, Battegay M, Phillips A, Bonnet F, Reiss P, Pradier C, Grulich A, Sabin C, Lundgren J, Mocroft A.

J Natl Cancer Inst. 2018 Jun 1;110(6):598-607. doi: 10.1093/jnci/djx249.


Durability of Second Antiretroviral Regimens in the Italian Cohort Naive Antiretrovirals Foundation Study and Factors Associated with Discontinuation.

Di Biagio A, Lorenzini P, Gustinetti G, Rusconi S, De Luca A, Lapadula G, Lo Caputo S, Cicalini S, Castelli F, Marchetti G, Antinori A, Monforte AD.

AIDS Patient Care STDS. 2017 Dec;31(12):487-494. doi: 10.1089/apc.2017.0140.


Cardiovascular disease (CVD) and chronic kidney disease (CKD) event rates in HIV-positive persons at high predicted CVD and CKD risk: A prospective analysis of the D:A:D observational study.

Boyd MA, Mocroft A, Ryom L, Monforte AD, Sabin C, El-Sadr WM, Hatleberg CI, De Wit S, Weber R, Fontas E, Phillips A, Bonnet F, Reiss P, Lundgren J, Law M.

PLoS Med. 2017 Nov 7;14(11):e1002424. doi: 10.1371/journal.pmed.1002424. eCollection 2017 Nov.


QTL Analyses in Multiple Populations Employed for the Fine Mapping and Identification of Candidate Genes at a Locus Affecting Sugar Accumulation in Melon (Cucumis melo L.).

Argyris JM, Díaz A, Ruggieri V, Fernández M, Jahrmann T, Gibon Y, Picó B, Martín-Hernández AM, Monforte AJ, Garcia-Mas J.

Front Plant Sci. 2017 Sep 26;8:1679. doi: 10.3389/fpls.2017.01679. eCollection 2017.


CD4:CD8 Ratio and CD8 Count as Prognostic Markers for Mortality in Human Immunodeficiency Virus-Infected Patients on Antiretroviral Therapy: The Antiretroviral Therapy Cohort Collaboration (ART-CC).

Trickey A, May MT, Schommers P, Tate J, Ingle SM, Guest JL, Gill MJ, Zangerle R, Saag M, Reiss P, Monforte AD, Johnson M, Lima VD, Sterling TR, Cavassini M, Wittkop L, Costagliola D, Sterne JAC; Antiretroviral Therapy Cohort Collaboration (ART-CC).

Clin Infect Dis. 2017 Sep 15;65(6):959-966. doi: 10.1093/cid/cix466.


Untargeted metabolomics of fresh and heat treatment Tiger nut (Cyperus esculentus L.) milks reveals further insight into food quality and nutrition.

Rubert J, Monforte A, Hurkova K, Pérez-Martínez G, Blesa J, Navarro JL, Stranka M, Soriano JM, Hajslova J.

J Chromatogr A. 2017 Sep 8;1514:80-87. doi: 10.1016/j.chroma.2017.07.071. Epub 2017 Jul 23.


Evolution of the prevalence of hepatitis C virus infection and hepatitis C virus genotype distribution in human immunodeficiency virus-infected patients in Italy between 1997 and 2015.

Rossetti B, Bai F, Tavelli A, Galli M, Antinori A, Castelli F, Pellizzer G, Cozzi-Lepri A, Bonora S, Monforte AD, Puoti M, De Luca A; ICONA Foundation study group.

Clin Microbiol Infect. 2018 Apr;24(4):422-427. doi: 10.1016/j.cmi.2017.07.021. Epub 2017 Jul 29.


Quantitative trait loci analysis of melon (Cucumis melo L.) domestication-related traits.

Díaz A, Martín-Hernández AM, Dolcet-Sanjuan R, Garcés-Claver A, Álvarez JM, Garcia-Mas J, Picó B, Monforte AJ.

Theor Appl Genet. 2017 Sep;130(9):1837-1856. doi: 10.1007/s00122-017-2928-y. Epub 2017 Jun 5.


Searching for novel N1-substituted benzimidazol-2-ones as non-nucleoside HIV-1 RT inhibitors.

Ferro S, Buemi MR, De Luca L, Agharbaoui FE, Pannecouque C, Monforte AM.

Bioorg Med Chem. 2017 Jul 15;25(14):3861-3870. doi: 10.1016/j.bmc.2017.05.040. Epub 2017 May 19.


Use of Natural Diversity and Biotechnology to Increase the Quality and Nutritional Content of Tomato and Grape.

Gascuel Q, Diretto G, Monforte AJ, Fortes AM, Granell A.

Front Plant Sci. 2017 May 12;8:652. doi: 10.3389/fpls.2017.00652. eCollection 2017. Review.


ETHQV6.3 is involved in melon climacteric fruit ripening and is encoded by a NAC domain transcription factor.

Ríos P, Argyris J, Vegas J, Leida C, Kenigswald M, Tzuri G, Troadec C, Bendahmane A, Katzir N, Picó B, Monforte AJ, Garcia-Mas J.

Plant J. 2017 Aug;91(4):671-683. doi: 10.1111/tpj.13596. Epub 2017 Jun 22.


Uncovering tomato quantitative trait loci and candidate genes for fruit cuticular lipid composition using the Solanum pennellii introgression line population.

Fernandez-Moreno JP, Levy-Samoha D, Malitsky S, Monforte AJ, Orzaez D, Aharoni A, Granell A.

J Exp Bot. 2017 May 17;68(11):2703-2716. doi: 10.1093/jxb/erx134.


Strecker Aldehyde Formation in Wine: New Insights into the Role of Gallic Acid, Glucose, and Metals in Phenylacetaldehyde Formation.

Monforte AR, Martins SIFS, Silva Ferreira AC.

J Agric Food Chem. 2018 Mar 14;66(10):2459-2466. doi: 10.1021/acs.jafc.7b00264. Epub 2017 Mar 9.


A chemical genetic roadmap to improved tomato flavor.

Tieman D, Zhu G, Resende MF Jr, Lin T, Nguyen C, Bies D, Rambla JL, Beltran KS, Taylor M, Zhang B, Ikeda H, Liu Z, Fisher J, Zemach I, Monforte A, Zamir D, Granell A, Kirst M, Huang S, Klee H.

Science. 2017 Jan 27;355(6323):391-394. doi: 10.1126/science.aal1556.


An SNP-based saturated genetic map and QTL analysis of fruit-related traits in Zucchini using Genotyping-by-sequencing.

Montero-Pau J, Blanca J, Esteras C, Martínez-Pérez EM, Gómez P, Monforte AJ, Cañizares J, Picó B.

BMC Genomics. 2017 Jan 18;18(1):94. doi: 10.1186/s12864-016-3439-y.


Identification, introgression, and validation of fruit volatile QTLs from a red-fruited wild tomato species.

Rambla JL, Medina A, Fernández-Del-Carmen A, Barrantes W, Grandillo S, Cammareri M, López-Casado G, Rodrigo G, Alonso A, García-Martínez S, Primo J, Ruiz JJ, Fernández-Muñoz R, Monforte AJ, Granell A.

J Exp Bot. 2017 Jan 1;68(3):429-442. doi: 10.1093/jxb/erw455.


Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Combination Treatment in Patients with HIV/HCV Co-Infection: Results of an Italian Compassionate Use Program.

Massimo A, Teti E, Antinori A, Milazzoi L, Sollima S, Rizzardini G, Di Biagio A, Saracino A, Bruno R, Borghi V, De Luca A, Cattelan A, Hasson H, Taliani G, Monforte AD, Mastroianni CM, Di Perri G, Bigoni S, Puoti M, Spinetti A, Gori A, Boffa N, Bruno C, Giacometti A, Parruti G, Vullo V, Chirianni A, Pennica A, Pasquazzi C, Segala D, Sarmati L; SIMIT (Società Italiana di Malattie Infettivee Tropicali).

Clin Infect Dis. 2017 Mar 1;64(5):680-683. doi: 10.1093/cid/ciw846. Epub 2016 Dec 22.


Clinical and viro-immunological correlates of HIV associated neurocognitive disorders (HAND) in a cohort of antiretroviral-naïve HIV-infected patients.

Bai F, Iannuzzi F, Merlini E, Borghi L, Tincati C, Trunfio M, Bini T, Monforte AD, Marchetti G.

AIDS. 2017 Jan 14;31(2):311-314. doi: 10.1097/QAD.0000000000001346.


Switch of predicted HIV-1 tropism in treated subjects and its association with disease progression.

Castagna A, Monno L, Carta S, Galli L, Carrara S, Fedele V, Punzi G, Fanti I, Caramello P, Lepri AC, De Luca A, Ceccherini-Silberstein F, Monforte AD; ICONA Foundation Study Group.

Medicine (Baltimore). 2016 Nov;95(44):e5222.


Cell-Mediated Immunity in HIV-Infected Males With Human Papillomavirus-Related Anal Dysplastic Lesions.

Tincati C, Rainone V, Comi L, Pandolfo A, Barco A, Bellistrì GM, Rovati M, Monforte AD, Trabattoni D, Marchetti G.

Clin Infect Dis. 2016 Nov 15;63(10):1396-1398. Epub 2016 Aug 30. No abstract available.


High-density lipoprotein-cholesterol levels and risk of cancer in HIV-infected subjects: Data from the ICONA Foundation Cohort.

Squillace N, Galli L, Bandera A, Castagna A, Madeddu G, Caramello P, Antinori A, Cattelan A, Maggiolo F, Cingolani A, Gori A, Monforte Ad; ICONA Foundation Study Group.

Medicine (Baltimore). 2016 Sep;95(36):e4434. doi: 10.1097/MD.0000000000004434.


Exploring New Alleles Involved in Tomato Fruit Quality in an Introgression Line Library of Solanum pimpinellifolium.

Barrantes W, López-Casado G, García-Martínez S, Alonso A, Rubio F, Ruiz JJ, Fernández-Muñoz R, Granell A, Monforte AJ.

Front Plant Sci. 2016 Aug 17;7:1172. doi: 10.3389/fpls.2016.01172. eCollection 2016.


The HIV-1 reverse transcriptase polymorphism A98S improves the response to tenofovir disoproxil fumarate+emtricitabine-containing HAART both in vivo and in vitro.

Alteri C, Surdo M, Di Maio VC, Di Santo F, Costa G, Parrotta L, Romeo I, Gori C, Santoro MM, Fedele V, Carta S, Continenza F, Pinnetti C, Bellagamba R, Liuzzi G, Orchi N, Latini A, Bertoli A, Girardi E, Alcaro S, Giuliani M, Petrosillo N, Andreoni M, Antinori A, Monforte AD, Ceccherini-Silberstein F, Artese A, Perno CF, Svicher V.

J Glob Antimicrob Resist. 2016 Dec;7:1-7. doi: 10.1016/j.jgar.2016.06.005. Epub 2016 Jul 25.


A new genomic library of melon introgression lines in a cantaloupe genetic background for dissecting desirable agronomical traits.

Perpiñá G, Esteras C, Gibon Y, Monforte AJ, Picó B.

BMC Plant Biol. 2016 Jul 8;16(1):154. doi: 10.1186/s12870-016-0842-0.


Effectiveness, durability, and safety of darunavir/ritonavir in HIV-1-infected patients in routine clinical practice in Italy: a postauthorization noninterventional study.

Antinori A, Meraviglia P, Monforte Ad, Castagna A, Mussini C, Bini T, Gianotti N, Rusconi S, Colella E, Airoldi G, Mancusi D, Termini R.

Drug Des Devel Ther. 2016 May 6;10:1589-603. doi: 10.2147/DDDT.S104875. eCollection 2016.


Longitudinal analysis of the associations between antiretroviral therapy, viraemia and immunosuppression with lipid levels: the D:A:D study.

Kamara DA, Smith C, Ryom L, Reiss P, Rickenbach M, Phillips A, Mocroft A, De Wit S, Law M, Monforte AD, Dabis F, Pradier C, Lundgren JD, Sabin C.

Antivir Ther. 2016;21(6):495-506. doi: 10.3851/IMP3051. Epub 2016 Apr 26.


Mortality According to CD4 Count at Start of Combination Antiretroviral Therapy Among HIV-infected Patients Followed for up to 15 Years After Start of Treatment: Collaborative Cohort Study.

May MT, Vehreschild JJ, Trickey A, Obel N, Reiss P, Bonnet F, Mary-Krause M, Samji H, Cavassini M, Gill MJ, Shepherd LC, Crane HM, d'Arminio Monforte A, Burkholder GA, Johnson MM, Sobrino-Vegas P, Domingo P, Zangerle R, Justice AC, Sterling TR, Miró JM, Sterne JAC; Antiretroviral Therapy Cohort Collaboration (ART-CC), Boulle A, Stephan C, Miro JM, Cavassini M, Chêne G, Costagliola D, Dabis F, Monforte AD, Del Amo J, Van Sighem A, Fätkenheuer G, Gill J, Guest J, Haerry DH, Hogg R, Justice A, Shepherd L, Obel N, Crane H, Smith C, Reiss P, Saag M, Sterling T, Teira R, Williams M, Zangerle R, Sterne J, May M, Ingle S, Trickey A.

Clin Infect Dis. 2016 Jun 15;62(12):1571-1577. doi: 10.1093/cid/ciw183. Epub 2016 Mar 29.


Improvements over time in short-term mortality following myocardial infarction in HIV-positive individuals.

Hatleberg CI, Ryom L, El-Sadr W, Smith C, Weber R, Reiss P, Fontas E, Dabis F, Law M, Monforte Ad, De Wit S, Mocroft A, Phillips A, Lundgren JD, Sabin C; D:A:D Study Group.

AIDS. 2016 Jun 19;30(10):1583-96. doi: 10.1097/QAD.0000000000001076.


In Vivo Evaluation of Selective Carbonic Anhydrase Inhibitors as Potential Anticonvulsant Agents.

Bruno E, Buemi MR, De Luca L, Ferro S, Monforte AM, Supuran CT, Vullo D, De Sarro G, Russo E, Gitto R.

ChemMedChem. 2016 Aug 19;11(16):1812-8. doi: 10.1002/cmdc.201500596. Epub 2016 Feb 24.


Is nelfinavir exposure associated with cancer incidence in HIV-positive individuals?

Boettiger DC, Sabin CA, Grulich A, Ryom L, Bonnet F, Reiss P, Monforte Ad, Kirk O, Phillips A, Bower M, Fätkenheuer G, Lundgren JD, Law M; Data collection on Adverse events of Anti-HIV Drugs (D:A:D) study group.

AIDS. 2016 Jun 19;30(10):1629-37. doi: 10.1097/QAD.0000000000001053.


Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: a prospective international cohort study.

Mocroft A, Lundgren JD, Ross M, Fux CA, Reiss P, Moranne O, Morlat P, Monforte Ad, Kirk O, Ryom L; Data Collection on Adverse events of Anti-HIV Drugs (D:A:D) Study.

Lancet HIV. 2016 Jan;3(1):e23-32. doi: 10.1016/S2352-3018(15)00211-8. Epub 2015 Nov 17.


Use of antiretroviral therapy and risk of end-stage liver disease and hepatocellular carcinoma in HIV-positive persons.

Ryom L, Lundgren JD, De Wit S, Kovari H, Reiss P, Law M, El-Sadr W, Monforte AD, Mocroft A, Smith C, Fontas E, Dabis F, Phillips A, Sabin C; D:A:D Study Group.

AIDS. 2016 Jul 17;30(11):1731-43. doi: 10.1097/QAD.0000000000001018.


Late presentation for HIV care across Europe: update from the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study, 2010 to 2013.

Late presenters working group in COHERE in EuroCoord, Mocroft A, Lundgren J, Antinori A, Monforte Ad, Brännström J, Bonnet F, Brockmeyer N, Casabona J, Castagna A, Costagliola D, De Wit S, Fätkenheuer G, Furrer H, Jadand C, Johnson A, Lazanas M, Leport C, Moreno S, Mussini C, Obel N, Post F, Reiss P, Sabin C, Skaletz-Rorowski A, Suarez-Loano I, Torti C, Warszawski J, Wittkop L, Zangerle R, Chene G, Raben D, Kirk O.

Euro Surveill. 2015;20(47). doi: 10.2807/1560-7917.ES.2015.20.47.30070.


Characterisation of long-term non-progression of HIV-1 infection after seroconversion: a cohort study.

van der Helm JJ, Geskus R, Lodi S, Meyer L, Schuitemaker H, Gunsenheimer-Bartmeyer B, Monforte Ad, Olson A, Touloumi G, Sabin C, Porter K, Prins M; CASCADE Collaboration in EuroCoord.

Lancet HIV. 2014 Oct;1(1):e41-8. doi: 10.1016/S2352-3018(14)70016-5. Epub 2014 Sep 18.


Variability of candidate genes, genetic structure and association with sugar accumulation and climacteric behavior in a broad germplasm collection of melon (Cucumis melo L.).

Leida C, Moser C, Esteras C, Sulpice R, Lunn JE, de Langen F, Monforte AJ, Picó B.

BMC Genet. 2015 Mar 19;16:28. doi: 10.1186/s12863-015-0183-2.


An updated prediction model of the global risk of cardiovascular disease in HIV-positive persons: The Data-collection on Adverse Effects of Anti-HIV Drugs (D:A:D) study.

Friis-Møller N, Ryom L, Smith C, Weber R, Reiss P, Dabis F, De Wit S, Monforte AD, Kirk O, Fontas E, Sabin C, Phillips A, Lundgren J, Law M; D:A:D study group.

Eur J Prev Cardiol. 2016 Jan;23(2):214-23. doi: 10.1177/2047487315579291. Epub 2015 Apr 16.


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