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Management of People With a Fontan Circulation: a Cardiac Society of Australia and New Zealand Position statement.

Zentner D, Celermajer DS, Gentles T, d'Udekem Y, Ayer J, Blue GM, Bridgman C, Burchill L, Cheung M, Cordina R, Culnane E, Davis A, du Plessis K, Eagleson K, Finucane K, Frank B, Greenway S, Grigg L, Hardikar W, Hornung T, Hynson J, Iyengar AJ, James P, Justo R, Kalman J, Kasparian N, Le B, Marshall K, Mathew J, McGiffin D, McGuire M, Monagle P, Moore B, Neilsen J, O'Connor B, O'Donnell C, Pflaumer A, Rice K, Sholler G, Skinner JR, Sood S, Ward J, Weintraub R, Wilson T, Wilson W, Winlaw D, Wood A.

Heart Lung Circ. 2019 Nov 14. pii: S1443-9506(19)31458-1. doi: 10.1016/j.hlc.2019.09.010. [Epub ahead of print]


Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial.

Male C, Lensing AWA, Palumbo JS, Kumar R, Nurmeev I, Hege K, Bonnet D, Connor P, Hooimeijer HL, Torres M, Chan AKC, Kenet G, Holzhauer S, Santamaría A, Amedro P, Chalmers E, Simioni P, Bhat RV, Yee DL, Lvova O, Beyer-Westendorf J, Biss TT, Martinelli I, Saracco P, Peters M, Kállay K, Gauger CA, Massicotte MP, Young G, Pap AF, Majumder M, Smith WT, Heubach JF, Berkowitz SD, Thelen K, Kubitza D, Crowther M, Prins MH, Monagle P; EINSTEIN-Jr Phase 3 Investigators.

Lancet Haematol. 2019 Nov 4. pii: S2352-3026(19)30219-4. doi: 10.1016/S2352-3026(19)30219-4. [Epub ahead of print]


Platelet Phenotype and Function in the Setting of Pediatric Extracorporeal Membrane Oxygenation (ECMO): A Systematic Review.

Yaw HP, Van Den Helm S, MacLaren G, Linden M, Monagle P, Ignjatovic V.

Front Cardiovasc Med. 2019 Sep 18;6:137. doi: 10.3389/fcvm.2019.00137. eCollection 2019.


A multi-national trial of a direct oral anticoagulant in children with cardiac disease: Design and rationale of the Safety of ApiXaban On Pediatric Heart disease On the preventioN of Embolism (SAXOPHONE) study.

Payne RM, Burns KM, Glatz AC, Li D, Li X, Monagle P, Newburger JW, Swan EA, Wheaton O, Male C; Pediatric Heart Network Investigators.

Am Heart J. 2019 Nov;217:52-63. doi: 10.1016/j.ahj.2019.08.002. Epub 2019 Aug 9.


Reference Values for 30 Common Biochemistry Analytes Across 5 Different Analyzers in Neonates and Children 30 Days to 18 Years of Age.

Hoq M, Matthews S, Karlaftis V, Burgess J, Cowley J, Donath S, Carlin J, Yen T, Ignjatovic V, Monagle P; HAPPI Kids study team.

Clin Chem. 2019 Oct;65(10):1317-1326. doi: 10.1373/clinchem.2019.306431. Epub 2019 Sep 3.


Bodyweight-adjusted rivaroxaban for children with venous thromboembolism (EINSTEIN-Jr): results from three multicentre, single-arm, phase 2 studies.

Monagle P, Lensing AWA, Thelen K, Martinelli I, Male C, Santamaría A, Samochatova E, Kumar R, Holzhauer S, Saracco P, Simioni P, Robertson J, Grangl G, Halton J, Connor P, Young G, Molinari AC, Nowak-Göttl U, Kenet G, Kapsa S, Willmann S, Pap AF, Becka M, Twomey T, Beyer-Westendorf J, Prins MH, Kubitza D; EINSTEIN-Jr Phase 2 Investigators.

Lancet Haematol. 2019 Oct;6(10):e500-e509. doi: 10.1016/S2352-3026(19)30161-9. Epub 2019 Aug 13.


Investigation of the in vitro effect of aspirin and tirofiban in children compared to adults.

McCafferty C, Busuttil-Crellin X, Cowley J, Linden M, Monagle P, Ignjatovic V.

Thromb Res. 2019 Sep;181:67-70. doi: 10.1016/j.thromres.2019.06.016. Epub 2019 Jun 27. No abstract available.


Development and Validation of the Warfarin-Aspirin Bleeding Assessment Tool (WA-BAT) in Children.

Attard C, Huang J, Newall F, Monagle P, d'Udekem Y, Ignjatovic V.

J Pediatr Hematol Oncol. 2019 Jun 27. doi: 10.1097/MPH.0000000000001540. [Epub ahead of print]


Antithrombotic management and thrombosis rates in children post-liver transplantation: A case series and literature review.

Flynn E, Huang JY, Hardikar W, Herd L, Hodgson A, Monagle P.

Pediatr Transplant. 2019 Jun;23(4):e13420. doi: 10.1111/petr.13420. Epub 2019 Apr 23.


A prospective, cross-sectional study to establish age-specific reference intervals for neonates and children in the setting of clinical biochemistry, immunology and haematology: the HAPPI Kids study protocol.

Hoq M, Karlaftis V, Mathews S, Burgess J, Donath SM, Carlin J, Monagle P, Ignjatovic V.

BMJ Open. 2019 Apr 3;9(4):e025897. doi: 10.1136/bmjopen-2018-025897.


Mathematical modelling indicates that lower activity of the haemostatic system in neonates is primarily due to lower prothrombin concentration.

Siekmann I, Bjelosevic S, Landman K, Monagle P, Ignjatovic V, Crampin EJ.

Sci Rep. 2019 Mar 8;9(1):3936. doi: 10.1038/s41598-019-40435-7.


Decreased placental glypican expression is associated with human fetal growth restriction.

Gunatillake T, Chui A, Fitzpatrick E, Ignjatovic V, Monagle P, Whitelock J, Zanten D, Eijsink J, Borg A, Stevenson J, Brennecke SP, Erwich JJHM, Said JM, Murthi P.

Placenta. 2019 Jan 15;76:6-9. doi: 10.1016/j.placenta.2018.12.007. Epub 2018 Dec 21.


Rivaroxaban versus standard anticoagulation for acute venous thromboembolism in childhood. Design of the EINSTEIN-Jr phase III study.

Lensing AWA, Male C, Young G, Kubitza D, Kenet G, Patricia Massicotte M, Chan A, Molinari AC, Nowak-Goettl U, Pap ÁF, Adalbo I, Smith WT, Mason A, Thelen K, Berkowitz SD, Crowther M, Schmidt S, Price V, Prins MH, Monagle P.

Thromb J. 2018 Dec 21;16:34. doi: 10.1186/s12959-018-0188-y. eCollection 2018.


Antiplatelet Therapy Monitoring in Neonates and Children.

Huang JY, Soeharto DA, Damara I, Ignjatovic V, Linden MD, Monagle P.

Semin Thromb Hemost. 2019 Feb;45(1):73-85. doi: 10.1055/s-0038-1676375. Epub 2018 Dec 19. Review.


Exploratory evaluation of pharmacodynamics, pharmacokinetics and safety of rivaroxaban in children and adolescents: an EINSTEIN-Jr phase I study.

Kubitza D, Willmann S, Becka M, Thelen K, Young G, Brandão LR, Monagle P, Male C, Chan A, Kennet G, Martinelli I, Saracco P, Lensing AWA.

Thromb J. 2018 Dec 4;16:31. doi: 10.1186/s12959-018-0186-0. eCollection 2018.


Management of thrombosis in children and neonates: practical use of anticoagulants in children.

Monagle P, Newall F.

Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):399-404. doi: 10.1182/asheducation-2018.1.399. Review.


Family history of venous thromboembolism in the paediatric population: The need for a standardized definition.

Hau A, Wegener E, Ignjatovic V, Revel-Vilk S, Monagle P.

Thromb Res. 2019 Jan;173:91-95. doi: 10.1016/j.thromres.2018.11.016. Epub 2018 Nov 16. Review.


American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism.

Monagle P, Cuello CA, Augustine C, Bonduel M, Brandão LR, Capman T, Chan AKC, Hanson S, Male C, Meerpohl J, Newall F, O'Brien SH, Raffini L, van Ommen H, Wiernikowski J, Williams S, Bhatt M, Riva JJ, Roldan Y, Schwab N, Mustafa RA, Vesely SK.

Blood Adv. 2018 Nov 27;2(22):3292-3316. doi: 10.1182/bloodadvances.2018024786.


Bleeding and thrombotic events occur early in children on durable ventricular assist devices.

Huang JY, Ignjatovic V, Sheridan BJ, Mathew J, D'Udekem Y, Brink J, Barton R, Callea G, Morsman D, Donath S, Opat S, Monagle P.

Thromb Res. 2019 Jan;173:65-70. doi: 10.1016/j.thromres.2018.11.019. Epub 2018 Nov 22.


Clinical presentation and therapeutic management of venous thrombosis in young children: a retrospective analysis.

Chan A, Lensing AWA, Kubitza D, Brown G, Elorza D, Ybarra M, Halton J, Grunt S, Kenet G, Bonnet D, Santamaria A, Saracco P, Biss T, Climent F, Connor P, Palumbo J, Thelen K, Smith WT, Mason A, Adalbo I, Berkowitz SD, Hurst E, van Kesteren J, Young G, Monagle P.

Thromb J. 2018 Nov 1;16:29. doi: 10.1186/s12959-018-0182-4. eCollection 2018.


The natural history of asymptomatic central venous catheter-related thrombosis in critically ill children.

Jones S, Butt W, Monagle P, Cain T, Newall F.

Blood. 2019 Feb 21;133(8):857-866. doi: 10.1182/blood-2018-05-849737. Epub 2018 Oct 30.


Australian Clinical Consensus Guideline: The diagnosis and acute management of childhood stroke.

Medley TL, Miteff C, Andrews I, Ware T, Cheung M, Monagle P, Mandelstam S, Wray A, Pridmore C, Troedson C, Dale RC, Fahey M, Sinclair A, Walsh P, Stojanovski B, Mackay MT.

Int J Stroke. 2019 Jan;14(1):94-106. doi: 10.1177/1747493018799958. Epub 2018 Oct 4.


A review of commercially available thrombin generation assays.

Kintigh J, Monagle P, Ignjatovic V.

Res Pract Thromb Haemost. 2017 Oct 16;2(1):42-48. doi: 10.1002/rth2.12048. eCollection 2018 Jan. Review.


Slow progress. How do we shift the paradigm of thinking in pediatric thrombosis and anticoagulation?

Monagle P.

Thromb Res. 2019 Jan;173:186-190. doi: 10.1016/j.thromres.2018.07.016. Epub 2018 Jul 17. Review.


Treatment and secondary prophylaxis with ethanol lock therapy for central line-associated bloodstream infection in paediatric cancer: a randomised, double-blind, controlled trial.

Wolf J, Connell TG, Allison KJ, Tang L, Richardson J, Branum K, Borello E, Rubnitz JE, Gaur AH, Hakim H, Su Y, Federico SM, Mechinaud F, Hayden RT, Monagle P, Worth LJ, Curtis N, Flynn PM.

Lancet Infect Dis. 2018 Aug;18(8):854-863. doi: 10.1016/S1473-3099(18)30224-X. Epub 2018 Jun 5.


Motor function daily living skills 5 years after paediatric arterial ischaemic stroke: a prospective longitudinal study.

Cooper AN, Anderson V, Greenham M, Hearps S, Hunt RW, Mackay MT, Ditchfield M, Coleman L, Monagle P, Gordon AL.

Dev Med Child Neurol. 2019 Feb;61(2):161-167. doi: 10.1111/dmcn.13915. Epub 2018 May 30.


Anticoagulation during ECMO in neonatal and paediatric patients.

Barton R, Ignjatovic V, Monagle P.

Thromb Res. 2019 Jan;173:172-177. doi: 10.1016/j.thromres.2018.05.009. Epub 2018 May 8. Review.


Pathophysiology of thrombosis and anticoagulation post Fontan surgery.

Attard C, Huang J, Monagle P, Ignjatovic V.

Thromb Res. 2018 Dec;172:204-213. doi: 10.1016/j.thromres.2018.04.011. Epub 2018 Apr 14. Review.


Differentiating arterial ischaemic stroke from migraine in the paediatric emergency department.

Mackay MT, Lee M, Yock-Corrales A, Churilov L, Donnan GA, Monagle P, Babl FE.

Dev Med Child Neurol. 2018 Nov;60(11):1117-1122. doi: 10.1111/dmcn.13772. Epub 2018 Apr 14.


Antithrombotic therapies in children on durable Ventricular Assist Devices: A literature review.

Huang JY, Monagle P, Massicotte MP, VanderPluym CJ.

Thromb Res. 2018 Dec;172:194-203. doi: 10.1016/j.thromres.2018.02.145. Epub 2018 Mar 2. Review.


Social functioning following pediatric stroke: contribution of neurobehavioral impairment.

Greenham M, Gordon AL, Cooper A, Ditchfield M, Coleman L, Hunt RW, Mackay MT, Monagle P, Anderson V.

Dev Neuropsychol. 2018;43(4):312-328. doi: 10.1080/87565641.2018.1440557. Epub 2018 Feb 26.


Heparin mimetics with anticoagulant activity.

Nahain AA, Ignjatovic V, Monagle P, Tsanaktsidis J, Ferro V.

Med Res Rev. 2018 Sep;38(5):1582-1613. doi: 10.1002/med.21489. Epub 2018 Feb 15. Review.


The Pediatric Stroke Outcome Measure: A predictor of outcome following arterial ischemic stroke.

Cooper AN, Anderson V, Hearps S, Greenham M, Hunt RW, Mackay MT, Monagle P, Gordon AL.

Neurology. 2018 Jan 30;90(5):e365-e372. doi: 10.1212/WNL.0000000000004906.


Identifying low-grade cellular rejection after heart transplantation in children by using gene expression profiling.

Xin A, Lee MGY, Hu Y, Ignjatovic V, Shi WY, Shipp A, Praporski S, Kallies A, Weintraub RG, Monagle PT, Smyth GK, Konstantinov IE.

Physiol Genomics. 2018 Mar 1;50(3):190-196. doi: 10.1152/physiolgenomics.00046.2017. Epub 2017 Dec 20.


The enactment stage of end-of-life decision-making for children.

Sullivan JE, Gillam LH, Monagle PT.

Palliat Support Care. 2018 Jan 11:1-7. doi: 10.1017/S1478951517001110. [Epub ahead of print]


Antiangiogenic effects of decorin restored by unfractionated, low molecular weight, and nonanticoagulant heparins.

Chui AKL, Gunatillake TN, Ignjatovic V, Monagle PT, Murthi P, Brennecke SP, Whitelock JM, Said JM.

Blood Adv. 2017 Jul 3;1(16):1243-1253. doi: 10.1182/bloodadvances.2017004333. eCollection 2017 Jul 11.


Improving diagnosis of childhood arterial ischaemic stroke.

Mackay MT, Monagle P, Babl FE.

Expert Rev Neurother. 2017 Dec;17(12):1157-1165. doi: 10.1080/14737175.2017.1395699. Epub 2017 Nov 7. Review.


Impact of thrombelastography in paediatric intensive care.

Carter BG, Carland E, Monagle P, Horton SB, Butt W.

Anaesth Intensive Care. 2017 Sep;45(5):589-599.


Early predictors of psychosocial functioning 5 years after paediatric stroke.

Greenham M, Anderson V, Cooper A, Hearps S, Ditchfield M, Coleman L, Hunt RW, Mackay MT, Monagle P, Gordon AL.

Dev Med Child Neurol. 2017 Oct;59(10):1034-1041. doi: 10.1111/dmcn.13519. Epub 2017 Aug 17.


Comment on: Generation and optimization of the self-administered pediatric bleeding questionnaire and its validation as a screening tool for von Willebrand disease.

Attard C, Ignjatovic V, Monagle P, Newall F.

Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26725. Epub 2017 Jul 20. No abstract available.


Trajectories of Motor Recovery in the First Year After Pediatric Arterial Ischemic Stroke.

Cooper AN, Anderson V, Hearps S, Greenham M, Ditchfield M, Coleman L, Hunt RW, Mackay MT, Monagle P, Gordon AL.

Pediatrics. 2017 Aug;140(2). pii: e20163870. doi: 10.1542/peds.2016-3870. Epub 2017 Jul 14.


Characterization of the coagulation profile in children with liver disease and extrahepatic portal vein obstruction or shunt.

Beattie W, Magnusson M, Hardikar W, Monagle P, Ignjatovic V.

Pediatr Hematol Oncol. 2017 Mar;34(2):107-119. doi: 10.1080/08880018.2017.1313919. Epub 2017 Jun 1.


Anticoagulation therapy in neonates, children and adolescents.

Hepponstall M, Chan A, Monagle P.

Blood Cells Mol Dis. 2017 Sep;67:41-47. doi: 10.1016/j.bcmd.2017.05.008. Epub 2017 May 13. Review.


At last: evidence rather than emotion.

Monagle P.

Blood. 2017 May 18;129(20):2714-2715. doi: 10.1182/blood-2017-03-772095. No abstract available.


Expression of Biglycan in First Trimester Chorionic Villous Sampling Placental Samples and Altered Function in Telomerase-Immortalized Microvascular Endothelial Cells.

Chui A, Gunatillake T, Brennecke SP, Ignjatovic V, Monagle PT, Whitelock JM, van Zanten DE, Eijsink J, Wang Y, Deane J, Borg AJ, Stevenson J, Erwich JJ, Said JM, Murthi P.

Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1168-1179. doi: 10.1161/ATVBAHA.117.309422. Epub 2017 Apr 13.


Quantitative Age-specific Variability of Plasma Proteins in Healthy Neonates, Children and Adults.

Bjelosevic S, Pascovici D, Ping H, Karlaftis V, Zaw T, Song X, Molloy MP, Monagle P, Ignjatovic V.

Mol Cell Proteomics. 2017 May;16(5):924-935. doi: 10.1074/mcp.M116.066720. Epub 2017 Mar 23.


Accuracy and Reliability of Stroke Diagnosis in the Pediatric Emergency Department.

Mackay MT, Yock-Corrales A, Churilov L, Monagle P, Donnan GA, Babl FE.

Stroke. 2017 May;48(5):1198-1202. doi: 10.1161/STROKEAHA.116.015571. Epub 2017 Mar 23.


Prehospital Emergency Care in Childhood Arterial Ischemic Stroke.

Stojanovski B, Monagle PT, Mosley I, Churilov L, Newall F, Hocking G, Mackay MT.

Stroke. 2017 Apr;48(4):1095-1097. doi: 10.1161/STROKEAHA.116.014768. Epub 2017 Feb 24.


Psychosocial function in the first year after childhood stroke.

Greenham M, Anderson V, Hearps S, Ditchfield M, Coleman L, Mackay MT, Monagle P, Gordon AL.

Dev Med Child Neurol. 2017 Oct;59(10):1027-1033. doi: 10.1111/dmcn.13387. Epub 2017 Jan 25.


Antithrombin Administration in Extracorporeal Membrane Oxygenation Patients: Putting the Cart Before the Horse.

MacLaren G, Monagle P.

Pediatr Crit Care Med. 2016 Dec;17(12):1188-1189. No abstract available.


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