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Items: 25


Antibacterial drug discovery--then, now and the genomics future.

Monaghan RL, Barrett JF.

Biochem Pharmacol. 2006 Mar 30;71(7):901-9. Epub 2006 Feb 21. Review.


Fusidienol A: A Novel Ras Farnesyl-Protein Transferase Inhibitor from Phoma sp.

Singh SB, Ball RG, Zink DL, Monaghan RL, Polishook JD, Sanchez M, Pelaez F, Silverman KC, Lingham RB.

J Org Chem. 1997 Oct 17;62(21):7485-7488. No abstract available.


The preparation of zaragozic acid A analogues by directed biosynthesis.

Chen TS, Petuch B, MacConnell J, White R, Dezeny G, Arison B, Bergstrom JD, Colwell L, Huang L, Monaghan RL.

J Antibiot (Tokyo). 1994 Nov;47(11):1290-4.


Microbial transformation of L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease.

Chen TS, Doss GA, Hsu A, Hsu A, Lingham RB, White RF, Monaghan RL.

J Nat Prod. 1993 May;56(5):755-61.


Microbial hydroxylation and glucuronidation of the angiotensin II (AII) receptor antagonist MK 954.

Chen TS, So L, White R, Monaghan RL.

J Antibiot (Tokyo). 1993 Jan;46(1):131-4.


L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease. I. The producing organism and its fermentation.

Dombrowski AW, Bills GF, Sabnis G, Koupal LR, Meyer R, Ondeyka JG, Giacobbe RA, Monaghan RL, Lingham RB.

J Antibiot (Tokyo). 1992 May;45(5):671-8.


Bioactive microbial products: focus upon mechanism of action.

Monaghan RL, Tkacz JS.

Annu Rev Microbiol. 1990;44:271-301. Review. No abstract available.


L-681,572--a new antifungal agent. Isolation, characterization, and biological activity.

Chaiet L, Fromtling RA, Garrity GM, Monaghan RL, Hensens OD, Valiant ME, Zink DL.

J Antibiot (Tokyo). 1989 Nov;42(11):1718-21. No abstract available.


L-671,329, a new antifungal agent. I. Fermentation and isolation.

Schwartz RE, Giacobbe RA, Bland JA, Monaghan RL.

J Antibiot (Tokyo). 1989 Feb;42(2):163-7.


Novel cholecystokinin antagonists from Aspergillus alliaceus. I. Fermentation, isolation, and biological properties.

Goetz MA, Monaghan RL, Chang RS, Ondeyka J, Chen TB, Lotti VJ.

J Antibiot (Tokyo). 1988 Jul;41(7):875-7.


Difficidin and oxydifficidin: novel broad spectrum antibacterial antibiotics produced by Bacillus subtilis. I. Production, taxonomy and antibacterial activity.

Zimmerman SB, Schwartz CD, Monaghan RL, Pelak BA, Weissberger B, Gilfillan EC, Mochales S, Hernandez S, Currie SA, Tejera E, et al.

J Antibiot (Tokyo). 1987 Dec;40(12):1677-81.


Potent inhibitory effect of antibiotic 1233A on cholesterol biosynthesis which specifically blocks 3-hydroxy-3-methylglutaryl coenzyme A synthase.

Omura S, Tomoda H, Kumagai H, Greenspan MD, Yodkovitz JB, Chen JS, Alberts AW, Martin I, Mochales S, Monaghan RL, et al.

J Antibiot (Tokyo). 1987 Sep;40(9):1356-7. No abstract available.


L-681,217, a new and novel member of the efrotomycin family of antibiotics.

Kempf AJ, Wilson KE, Hensens OD, Monaghan RL, Zimmerman SB, Dulaney EL.

J Antibiot (Tokyo). 1986 Oct;39(10):1361-7.


Asperlicin, a novel non-peptidal cholecystokinin antagonist from Aspergillus alliaceus. Fermentation, isolation and biological properties.

Goetz MA, Lopez M, Monaghan RL, Chang RS, Lotti VJ, Chen TB.

J Antibiot (Tokyo). 1985 Dec;38(12):1633-7.


A potent nonpeptide cholecystokinin antagonist selective for peripheral tissues isolated from Aspergillus alliaceus.

Chang RS, Lotti VJ, Monaghan RL, Birnbaum J, Stapley EO, Goetz MA, Albers-Schönberg G, Patchett AA, Liesch JM, Hensens OD, et al.

Science. 1985 Oct 11;230(4722):177-9.


L-155,175: a new antiparasitic macrolide. Fermentation, isolation and structure.

Goetz MA, McCormick PA, Monaghan RL, Ostlind DA, Hensens OD, Liesch JM, Albers-Schonberg G.

J Antibiot (Tokyo). 1985 Feb;38(2):161-8.


Discovery, production and purification of the Na+, K+ activated ATPase inhibitor, L-681,110 from the fermentation broth of Streptomyces sp. MA-5038.

Huang L, Albers-Schonberg G, Monaghan RL, Jakubas K, Pong SS, Hensens OD, Burg RW, Ostlind DA, Conroy J, Stapley EO.

J Antibiot (Tokyo). 1984 Sep;37(9):970-5.


[R-(Z)]-4-amino-3-chloro-2-pentenedioic acid, a new antibiotic. Fermentation, isolation and characterization.

Chaiet L, Arison BH, Monaghan RL, Springer JP, Smith JL, Zimmerman SB.

J Antibiot (Tokyo). 1984 Mar;37(3):207-10.


Epithienamycins-novel beta-lactams related to thienamycin. I. Production and antibacterial activity.

Stapley EO, Cassidy PJ, Tunac J, Monaghan RL, Jackson M, Hernandez S, Zimmerman SB, Mata JM, Currie SA, Daoust D, Hendlin D.

J Antibiot (Tokyo). 1981 Jun;34(6):628-36.


Dihydrocompactin, a new potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase from Penicillium citrinum.

Lam YK, Gullo VP, Goegelman RT, Jorn D, Huang L, DeRiso C, Monaghan RL, Putter I.

J Antibiot (Tokyo). 1981 May;34(5):614-6. No abstract available.


Avermectins, new family of potent anthelmintic agents: isolation and chromatographic properties.

Miller TW, Chaiet L, Cole DJ, Cole LJ, Flor JE, Goegelman RT, Gullo VP, Joshua H, Kempf AJ, Krellwitz WR, Monaghan RL, Ormond RE, Wilson KE, Albers-Schönberg G, Putter I.

Antimicrob Agents Chemother. 1979 Mar;15(3):368-71.


Avermectins, new family of potent anthelmintic agents: producing organism and fermentation.

Burg RW, Miller BM, Baker EE, Birnbaum J, Currie SA, Hartman R, Kong YL, Monaghan RL, Olson G, Putter I, Tunac JB, Wallick H, Stapley EO, Oiwa R, Omura S.

Antimicrob Agents Chemother. 1979 Mar;15(3):361-7.


Chitosanase, a novel enzyme.

Monaghan RL, Eveleigh DE, Tewari RP, Reese ET.

Nat New Biol. 1973 Sep 19;245(142):78-80. No abstract available.


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