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Items: 1 to 50 of 595

1.

Biological Effects of Ciliary Neurotrophic Factor on hMADS Adipocytes.

Perugini J, Di Mercurio E, Tossetta G, Severi I, Monaco F, Reguzzoni M, Tomasetti M, Dani C, Cinti S, Giordano A.

Front Endocrinol (Lausanne). 2019 Nov 12;10:768. doi: 10.3389/fendo.2019.00768. eCollection 2019.

2.

The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia.

Ciciarello M, Corradi G, Loscocco F, Visani G, Monaco F, Cavo M, Curti A, Isidori A.

Front Oncol. 2019 Oct 25;9:1135. doi: 10.3389/fonc.2019.01135. eCollection 2019. Review.

3.

Trials Focusing on Prevention and Treatment of Delirium After Cardiac Surgery: A systematic Review of Randomized Evidence.

Pieri M, De Simone A, Rose S, De Domenico P, Lembo R, Denaro G, Landoni G, Monaco F.

J Cardiothorac Vasc Anesth. 2019 Sep 24. pii: S1053-0770(19)30989-9. doi: 10.1053/j.jvca.2019.09.028. [Epub ahead of print] Review.

PMID:
31668634
4.

Detection of enzootic circulation of a new strain of West Nile virus lineage 1 in sentinel chickens in the north of Tunisia.

Amdouni J, Monaco F, Portanti O, Sghaier S, Conte A, Hassine TB, Polci A, Valleriani F, Gennaro AD, Zoueri M, Savini G, Hammami S.

Acta Trop. 2019 Oct 21;202:105223. doi: 10.1016/j.actatropica.2019.105223. [Epub ahead of print]

PMID:
31647898
5.

Noninvasive ventilation during left atrial appendage closure under sedation: Preliminary experience with the Janus Mask.

Zangrillo A, Mazzone P, Oriani A, Pieri M, Frau G, D'Angelo G, Sartini C, Capucci R, Belletti A, Bella PD, Monaco F.

Ann Card Anaesth. 2019 Oct-Dec;22(4):400-406. doi: 10.4103/aca.ACA_145_18.

6.

Tranexamic acid in open aortic aneurysm surgery: a randomised clinical trial.

Monaco F, Nardelli P, Pasin L, Barucco G, Mattioli C, Di Tomasso N, Dalessandro G, Giardina G, Landoni G, Chiesa R, Zangrillo A.

Br J Anaesth. 2019 Oct 10. pii: S0007-0912(19)30682-8. doi: 10.1016/j.bja.2019.08.028. [Epub ahead of print]

PMID:
31607387
7.

Assessing the role of migratory birds in the introduction of ticks and tick-borne pathogens from African countries: An Italian experience.

Pascucci I, Di Domenico M, Capobianco Dondona G, Di Gennaro A, Polci A, Capobianco Dondona A, Mancuso E, Cammà C, Savini G, Cecere JG, Spina F, Monaco F.

Ticks Tick Borne Dis. 2019 Oct;10(6):101272. doi: 10.1016/j.ttbdis.2019.101272. Epub 2019 Aug 16.

PMID:
31481344
8.

Differences in Biomarkers Pattern Between Severe Isolated Right and Left Ventricular Dysfunction After Cardiac Surgery.

Kim JH, Lerose CC, Landoni G, Di Prima AL, Licheri M, Oriani A, Alaidroos M, Zangrillo A, Monaco F.

J Cardiothorac Vasc Anesth. 2019 Jul 21. pii: S1053-0770(19)30767-0. doi: 10.1053/j.jvca.2019.07.128. [Epub ahead of print]

PMID:
31473115
9.

Exosomal transfer of miR-126 promotes the anti-tumour response in malignant mesothelioma: Role of miR-126 in cancer-stroma communication.

Monaco F, Gaetani S, Alessandrini F, Tagliabracci A, Bracci M, Valentino M, Neuzil J, Amati M, Bovenzi M, Tomasetti M, Santarelli L.

Cancer Lett. 2019 Oct 28;463:27-36. doi: 10.1016/j.canlet.2019.08.001. Epub 2019 Aug 7.

PMID:
31400405
10.

Treating hypofibrinogenaemia in major aortic surgery.

Monaco F, Nardelli P.

Anaesthesia. 2019 Aug;74(8):1062. doi: 10.1111/anae.14695. No abstract available.

PMID:
31282579
11.

Access instruments for video assisted surgery: combination of mini-invasivity and universality.

De Caridi G, Massara M, Serra R, Monaco F, Benedetto F.

J Thorac Dis. 2019 May;11(Suppl 9):S1375-S1376. doi: 10.21037/jtd.2019.03.70. No abstract available.

12.

Crimean-Congo Hemorrhagic Fever Virus Genome in Tick from Migratory Bird, Italy.

Mancuso E, Toma L, Polci A, d'Alessio SG, Di Luca M, Orsini M, Di Domenico M, Marcacci M, Mancini G, Spina F, Goffredo M, Monaco F.

Emerg Infect Dis. 2019 Jul;25(7):1418-1420. doi: 10.3201/eid2507.181345.

13.

Editor's Choice - A Rotational Thromboelastometry Driven Transfusion Strategy Reduces Allogenic Blood Transfusion During Open Thoraco-abdominal Aortic Aneurysm Repair: A Propensity Score Matched Study.

Monaco F, Barucco G, Nardelli P, Licheri M, Notte C, De Luca M, Mattioli C, Melissano G, Chiesa R, Zangrillo A.

Eur J Vasc Endovasc Surg. 2019 Jul;58(1):13-22. doi: 10.1016/j.ejvs.2019.02.009. Epub 2019 Jun 8.

PMID:
31186133
14.

Quality of life 10 years after cardiac surgery in adults: a long-term follow-up study.

Perrotti A, Ecarnot F, Monaco F, Dorigo E, Monteleone P, Besch G, Chocron S.

Health Qual Life Outcomes. 2019 May 22;17(1):88. doi: 10.1186/s12955-019-1160-7.

15.

Production of monoclonal antibodies binding to the VP7 protein of African horse sickness virus.

Luciani M, Armillotta G, Ciarelli A, Ulisse S, Teodori L, Bortone G, Giamboi A, Monaco F, Tittarelli M, Di Ventura M, Iannetti L, Podaliri Vulpiani M, Di Febo T.

J Virol Methods. 2019 Aug;270:131-136. doi: 10.1016/j.jviromet.2019.05.004. Epub 2019 May 13.

PMID:
31095974
16.

Lenalidomide Combination Therapy in Relapsed/Refractory Diffuse Large B Cell Lymphoma: The Italian Real-Life Experience.

Marangon M, Stefoni V, Castellino A, Visco C, Tani M, Cox MC, Marasca R, Tecchio C, Devizzi L, Monaco F, Romano A, Rusconi C, Rigacci L, Castellino C, Gaudio F, Argnani L, Zinzani PL.

Clin Lymphoma Myeloma Leuk. 2019 Jul;19(7):e321-e323. doi: 10.1016/j.clml.2019.03.020. Epub 2019 Mar 29. No abstract available.

PMID:
31080169
17.

A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Increasing Mortality.

Sartini C, Lomivorotov V, Pisano A, Riha H, Baiardo Redaelli M, Lopez-Delgado JC, Pieri M, Hajjar L, Fominskiy E, Likhvantsev V, Cabrini L, Bradic N, Avancini D, Wang CY, Lembo R, Novikov M, Paternoster G, Gazivoda G, Alvaro G, Roasio A, Wang C, Severi L, Pasin L, Mura P, Musu M, Silvetti S, Votta CD, Belletti A, Corradi F, Brusasco C, Tamà S, Ruggeri L, Yong CY, Pasero D, Mancino G, Spadaro S, Conte M, Lobreglio R, Di Fraja D, Saporito E, D'Amico A, Sardo S, Ortalda A, Yavorovskiy A, Riefolo C, Monaco F, Bellomo R, Zangrillo A, Landoni G.

J Cardiothorac Vasc Anesth. 2019 Oct;33(10):2685-2694. doi: 10.1053/j.jvca.2019.03.022. Epub 2019 Mar 23.

PMID:
31064730
18.

Immunological response in horses following West Nile virus vaccination with inactivated or recombinant vaccine.

Monaco F, Purpari G, Di Gennaro A, Mira F, Di Marco P, Guercio A, Savini G.

Vet Ital. 2019 Mar 31;55(1):73-79.

19.

Lenalidomide in Pretreated Patients with Diffuse Large B-Cell Lymphoma: An Italian Observational Multicenter Retrospective Study in Daily Clinical Practice.

Broccoli A, Casadei B, Chiappella A, Visco C, Tani M, Cascavilla N, Conconi A, Balzarotti M, Cox MC, Marino D, Goldaniga MC, Marasca R, Tecchio C, Patti C, Musuraca G, Devizzi L, Monaco F, Romano A, Fama A, Zancanella M, Paolini R, Rigacci L, Castellino C, Gaudio F, Argnani L, Zinzani PL.

Oncologist. 2019 Sep;24(9):1246-1252. doi: 10.1634/theoncologist.2018-0603. Epub 2019 Apr 2.

PMID:
30940746
20.

Predictors of Intensive Care Unit Admission in Patients Undergoing Lead Extraction: A 10-Year Observational Study in a High-Volume Center.

Monaco F, Di Tomasso N, Landoni G, Nardelli P, Radinovic A, Melillo F, D'Angelo G, Della Bella P, Zangrillo A, Mazzone P.

J Cardiothorac Vasc Anesth. 2019 Jul;33(7):1845-1851. doi: 10.1053/j.jvca.2019.02.012. Epub 2019 Feb 13.

PMID:
30898421
21.

Volatile Anesthetics versus Total Intravenous Anesthesia for Cardiac Surgery.

Landoni G, Lomivorotov VV, Nigro Neto C, Monaco F, Pasyuga VV, Bradic N, Lembo R, Gazivoda G, Likhvantsev VV, Lei C, Lozovskiy A, Di Tomasso N, Bukamal NAR, Silva FS, Bautin AE, Ma J, Crivellari M, Farag AMGA, Uvaliev NS, Carollo C, Pieri M, Kunstýř J, Wang CY, Belletti A, Hajjar LA, Grigoryev EV, Agrò FE, Riha H, El-Tahan MR, Scandroglio AM, Elnakera AM, Baiocchi M, Navalesi P, Shmyrev VA, Severi L, Hegazy MA, Crescenzi G, Ponomarev DN, Brazzi L, Arnoni R, Tarasov DG, Jovic M, Calabrò MG, Bove T, Bellomo R, Zangrillo A; MYRIAD Study Group.

N Engl J Med. 2019 Mar 28;380(13):1214-1225. doi: 10.1056/NEJMoa1816476. Epub 2019 Mar 19.

PMID:
30888743
22.

Prevalence and correlates of major depressive disorder, bipolar disorder and schizophrenia among nursing home residents without dementia: systematic review and meta-analysis.

Fornaro M, Solmi M, Stubbs B, Veronese N, Monaco F, Novello S, Fusco A, Anastasia A, De Berardis D, Carvalho AF, de Bartolomeis A, Vieta E.

Br J Psychiatry. 2019 Mar 13:1-10. doi: 10.1192/bjp.2019.5. [Epub ahead of print]

PMID:
30864533
23.

Mycobacterium saskatchewanense strain associated with a chronic kidney disease patient in an Italian transplantation hospital and almost misdiagnosed as Mycobacterium tuberculosis.

Di Mento G, Carreca AP, Monaco F, Cuscino N, Cardinale F, Conaldi PG, Douradinha B.

Infect Control Hosp Epidemiol. 2019 Apr;40(4):496-497. doi: 10.1017/ice.2019.6. Epub 2019 Feb 15. No abstract available.

PMID:
30767828
24.

Total body irradiation dose escalation decreases risk of progression and graft rejection after hematopoietic cell transplantation for myelodysplastic syndromes or myeloproliferative neoplasms.

Monaco F, Scott BL, Chauncey TR, Petersen FB, Storer BE, Baron F, Flowers ME, Deeg HJ, Maloney DG, Storb R, Sandmaier BM.

Haematologica. 2019 Jun;104(6):1221-1229. doi: 10.3324/haematol.2018.199398. Epub 2019 Jan 10.

25.

Anesthesiologic Management of Patients Undergoing Cardiac Transapical Procedures: Which Challenges in the Modern Era?

Pieri M, De Luca M, Gerli C, Crivellari M, Buzzatti N, Denti P, Stamelos M, Zangrillo A, Landoni G, Monaco F.

J Cardiothorac Vasc Anesth. 2019 Jul;33(7):1883-1889. doi: 10.1053/j.jvca.2018.10.039. Epub 2018 Oct 28.

PMID:
30581110
26.

Noninvasive Ventilation After Thoracoabdominal Aortic Surgery: A Pilot Randomized Controlled Trial.

Mamo D, Zangrillo A, Cabrini L, Leggieri C, Olper L, Monaco F, Nardelli P, Dalessandro G, Ponzetta G, Monti G, Landoni G, Greco M.

J Cardiothorac Vasc Anesth. 2019 Jun;33(6):1639-1645. doi: 10.1053/j.jvca.2018.10.041. Epub 2018 Nov 2.

PMID:
30502311
27.

Antigenic relationship among zoonotic flaviviruses from Italy.

Lorusso A, Marini V, Di Gennaro A, Ronchi GF, Casaccia C, Carelli G, Passantino G, D'Alterio N, D'Innocenzo V, Savini G, Monaco F, Horton DL.

Infect Genet Evol. 2019 Mar;68:91-97. doi: 10.1016/j.meegid.2018.11.023. Epub 2018 Dec 2.

PMID:
30517880
28.

Exploiting serological data to understand the epidemiology of bluetongue virus serotypes circulating in Libya.

Mahmoud AS, Savini G, Spedicato M, Monaco F, Carmine I, Lorusso A, Francesco T, Mazzei M, Forzan M, Eldaghayes I, Dayhum A.

Vet Med Sci. 2019 Feb;5(1):79-86. doi: 10.1002/vms3.136. Epub 2018 Nov 23.

29.

Rift Valley fever virus: a serological survey in Libyan ruminants.

Mahmoud AS, Di Sabatino D, Danzetta ML, Iapaolo F, Tolari F, Forzan M, Mazzei M, Dayhum A, De Massis F, Monaco F.

Open Vet J. 2018;8(2):204-207. doi: 10.4314/ovj.v8i2.15. Epub 2018 Jun 16.

30.

Epidural Analgesia in Open Thoraco-abdominal Aortic Aneurysm Repair.

Monaco F, Pieri M, Barucco G, Karpatri V, Redaelli MB, De Luca M, Mattioli C, Bove T, Melissano G, Chiesa R, Landoni G, Zangrillo A.

Eur J Vasc Endovasc Surg. 2019 Mar;57(3):360-367. doi: 10.1016/j.ejvs.2018.09.027. Epub 2018 Oct 29.

PMID:
30385186
31.

Anatomic and procedural associations of transcatheter heart valve displacement following Evolut R implantation.

Hachinohe D, Latib A, Laricchia A, Demir OM, Agricola E, Romano V, Del Sole PA, Leone PP, Ancona MB, Mangieri A, Regazzoli D, Giannini F, Mitomo S, Monaco F, Buzzatti N, Montorfano M, Colombo A.

Catheter Cardiovasc Interv. 2019 Feb 15;93(3):522-529. doi: 10.1002/ccd.27827. Epub 2018 Oct 4.

PMID:
30286515
32.

Four-miRNA Signature to Identify Asbestos-Related Lung Malignancies.

Santarelli L, Gaetani S, Monaco F, Bracci M, Valentino M, Amati M, Rubini C, Sabbatini A, Pasquini E, Zanotta N, Comar M, Neuzil J, Tomasetti M, Bovenzi M.

Cancer Epidemiol Biomarkers Prev. 2019 Jan;28(1):119-126. doi: 10.1158/1055-9965.EPI-18-0453. Epub 2018 Sep 26.

PMID:
30257964
33.

MiR-126 in intestinal-type sinonasal adenocarcinomas: exosomal transfer of MiR-126 promotes anti-tumour responses.

Tomasetti M, Re M, Monaco F, Gaetani S, Rubini C, Bertini A, Pasquini E, Bersaglieri C, Bracci M, Staffolani S, Colomba M, Gregorini A, Valentino M, Tagliabracci A, Bovenzi M, Neuzil J, Amati M, Santarelli L.

BMC Cancer. 2018 Sep 17;18(1):896. doi: 10.1186/s12885-018-4801-z.

34.

The identification of biomarkers predicting acute and maintenance lithium treatment response in bipolar disorder: A plea for further research attention.

Fornaro M, De Berardis D, Anastasia A, Novello S, Fusco A, Cattaneo CI, Solmi M, Monaco F, Veronese N, Kim YK, de Bartolomeis A.

Psychiatry Res. 2018 Nov;269:658-672. doi: 10.1016/j.psychres.2018.08.034. Epub 2018 Aug 16. Review.

PMID:
30216918
35.

Osteonecrosis of the Jaw in Myeloma Patients Receiving Denosumab or Zoledronic Acid. A Commentary of the Pivotal Trial by Raje et al. Published on Lancet Oncology.

Fusco V, Campisi G, de Boissieu P, Monaco F, Baraldi A, Numico G, Bedogni A.

Dent J (Basel). 2018 Sep 1;6(3). pii: E42. doi: 10.3390/dj6030042.

36.

Antibodies against Schmallenberg virus detected in cattle in the Otjozondjupa region, Namibia.

Molini U, Capobianco Dondona A, Hilbert R, Monaco F.

J S Afr Vet Assoc. 2018 Aug 16;89(0):e1-e2. doi: 10.4102/jsava.v89i0.1666.

37.

An early start of West Nile virus seasonal transmission: the added value of One Heath surveillance in detecting early circulation and triggering timely response in Italy, June to July 2018.

Riccardo F, Monaco F, Bella A, Savini G, Russo F, Cagarelli R, Dottori M, Rizzo C, Venturi G, Di Luca M, Pupella S, Lombardini L, Pezzotti P, Parodi P, Maraglino F, Costa AN, Liumbruno GM, Rezza G, The Working Group.

Euro Surveill. 2018 Aug;23(32). doi: 10.2807/1560-7917.ES.2018.23.32.1800427.

38.

Predictors of Advanced Conduction Disturbances Requiring a Late (≥48 H) Permanent Pacemaker Following Transcatheter Aortic Valve Replacement.

Mangieri A, Lanzillo G, Bertoldi L, Jabbour RJ, Regazzoli D, Ancona MB, Tanaka A, Mitomo S, Garducci S, Montalto C, Pagnesi M, Giannini F, Giglio M, Montorfano M, Chieffo A, Rodès-Cabau J, Monaco F, Paglino G, Della Bella P, Colombo A, Latib A.

JACC Cardiovasc Interv. 2018 Aug 13;11(15):1519-1526. doi: 10.1016/j.jcin.2018.06.014.

39.

DNA damage response in workers exposed to low-dose ionising radiation.

Gaetani S, Monaco F, Bracci M, Ciarapica V, Impollonia G, Valentino M, Tomasetti M, Santarelli L, Amati M.

Occup Environ Med. 2018 Oct;75(10):724-729. doi: 10.1136/oemed-2018-105094. Epub 2018 Aug 7.

PMID:
30087158
40.

Assessment of reproducibility of a VP7 Blocking ELISA diagnostic test for African horse sickness.

Durán-Ferrer M, Agüero M, Zientara S, Beck C, Lecollinet S, Sailleau C, Smith S, Potgieter C, Rueda P, Sastre P, Monaco F, Villalba R, Tena-Tomás C, Batten C, Frost L, Flannery J, Gubbins S, Lubisi BA, Sánchez-Vizcaíno JM, Emery M, Sturgill T, Ostlund E, Castillo-Olivares J.

Transbound Emerg Dis. 2019 Jan;66(1):83-90. doi: 10.1111/tbed.12968. Epub 2018 Aug 2.

41.

Peste des Petits Ruminants outbreaks in Tunisia in 2016.

Ben Hassen S, Monaco F, Sghaier S, Orsini M, Valleriani F, Haj Ammar H, Petrini A, Hammami S, Cosseddu GM.

Transbound Emerg Dis. 2018 Dec;65(6):1416-1420. doi: 10.1111/tbed.12985. Epub 2018 Aug 21.

PMID:
30062766
42.

Percutaneous Direct Annuloplasty With Edge-to-Edge Technique for Mitral Regurgitation: Replicating a Complete Surgical Mitral Repair in a One-Step Procedure.

Mangieri A, Colombo A, Demir OM, Agricola E, Ancona F, Regazzoli D, Ancona MB, Mitomo S, Lanzillo G, Del Sole PA, Monaco F, Pagnesi M, Montorfano M, Latib A.

Can J Cardiol. 2018 Aug;34(8):1088.e1-1088.e2. doi: 10.1016/j.cjca.2018.04.003. Epub 2018 Apr 6.

PMID:
30056846
43.

Anesthetic management of carcinoid heart disease after cardiac surgery. A possible use of veno-arterial extracorporeal membrane oxygenation support.

Di Tomasso N, Carcò F, Arangino C, De Luca M, Bove T, Zangrillo A, Monaco F.

J Clin Anesth. 2018 Nov;50:91-92. doi: 10.1016/j.jclinane.2018.06.036. Epub 2018 Jul 17. No abstract available.

PMID:
30015004
44.

Biomarkers in Pulmonary Hypertension.

Marra AM, Bossone E, Salzano A, D'Assante R, Monaco F, Ferrara F, Arcopinto M, Vriz O, Suzuki T, Cittadini A.

Heart Fail Clin. 2018 Jul;14(3):393-402. doi: 10.1016/j.hfc.2018.03.005. Review.

PMID:
29966636
45.

A Web Geographic Information System to share data and explorative analysis tools: The application to West Nile disease in the Mediterranean basin.

Savini L, Tora S, Di Lorenzo A, Cioci D, Monaco F, Polci A, Orsini M, Calistri P, Conte A.

PLoS One. 2018 Jun 27;13(6):e0196429. doi: 10.1371/journal.pone.0196429. eCollection 2018.

46.

Environmental risk factors and nonpharmacological and nonsurgical interventions for obesity: An umbrella review of meta-analyses of cohort studies and randomized controlled trials.

Solmi M, Köhler CA, Stubbs B, Koyanagi A, Bortolato B, Monaco F, Vancampfort D, Machado MO, Maes M, Tzoulaki I, Firth J, Ioannidis JPA, Carvalho AF.

Eur J Clin Invest. 2018 Dec;48(12):e12982. doi: 10.1111/eci.12982. Epub 2018 Jul 13.

PMID:
29923186
47.

Management of a case of unacknowledged foreign body in the upper airway.

D'Agostino FG, Monaco F, Mondello B, Familiari D, Barone M.

Asian Cardiovasc Thorac Ann. 2018 Jul;26(6):489-491. doi: 10.1177/0218492318783293. Epub 2018 Jun 7.

PMID:
29877718
48.

Prevalence of Usutu and West Nile virus antibodies in human sera, Modena, Italy, 2012.

Faggioni G, De Santis R, Pomponi A, Grottola A, Serpini GF, Meacci M, Gennari W, Tagliazucchi S, Pecorari M, Monaco F, Savini G, Benedetti E, Remoli ME, Fortuna C, Venturi G, Rezza G, Lista F.

J Med Virol. 2018 Oct;90(10):1666-1668. doi: 10.1002/jmv.25230. Epub 2018 Jun 6.

PMID:
29797606
49.

Infant colonisation with Escherichia coli and Klebsiella pneumoniae strains co-harbouring blaOXA-48 and blaNDM-1 carbapenemases genes: a case report.

Monaco F, Mento GD, Cuscino N, Conaldi PG, Douradinha B.

Int J Antimicrob Agents. 2018 Jul;52(1):121-122. doi: 10.1016/j.ijantimicag.2018.04.018. Epub 2018 May 9. No abstract available.

PMID:
29753131
50.

Rituximab plus bendamustine as front-line treatment in frail elderly (>70 years) patients with diffuse large B-cell non-Hodgkin lymphoma: a phase II multicenter study of the Fondazione Italiana Linfomi.

Storti S, Spina M, Pesce EA, Salvi F, Merli M, Ruffini A, Cabras G, Chiappella A, Angelucci E, Fabbri A, Liberati AM, Tani M, Musuraca G, Molinari A, Petrilli MP, Palladino C, Ciancia R, Ferrario A, Gasbarrino C, Monaco F, Fraticelli V, De Vellis A, Merli F, Luminari S.

Haematologica. 2018 Aug;103(8):1345-1350. doi: 10.3324/haematol.2017.186569. Epub 2018 May 10.

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