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2003 2
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Knockdown of MON1B Exerts Anti-Tumor Effects in Colon Cancer In Vitro.
Jiang L, Qian J, Yang Y, Fan Y. Jiang L, et al. Med Sci Monit. 2018 Oct 28;24:7710-7718. doi: 10.12659/MSM.911002. Med Sci Monit. 2018. PMID: 30368516 Free PMC article.
MON1B-silenced LoVo colon cancer cells were constructed. RT-qPCR and Western blot analysis were used to detect mRNA and protein levels, respectively, of colon cancer tissues and cells. ...CONCLUSIONS MON1B interference exerted anti-tumor effect in colon cancer in vi
MON1B-silenced LoVo colon cancer cells were constructed. RT-qPCR and Western blot analysis were used to detect mRNA and protein level
Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b.
Shao X, Liu Y, Yu Q, Ding Z, Qian W, Zhang L, Zhang J, Jiang N, Gui L, Xu Z, Hong Y, Ma Y, Wei Y, Liu X, Jiang C, Zhu M, Li H, Li H. Shao X, et al. Cell Res. 2016 May;26(5):593-612. doi: 10.1038/cr.2016.34. Epub 2016 Mar 18. Cell Res. 2016. PMID: 26987402 Free PMC article.
We further show that Numb binds to another docking regulator, Mon1b, and is required for the recruitment of cytosolic Mon1b to the EE membrane. Consistent with this, deletion of Mon1b causes similar defects in EE fusion. Our study thus identifies a novel mech …
We further show that Numb binds to another docking regulator, Mon1b, and is required for the recruitment of cytosolic Mon1b to …
Genome-Wide Association Analysis of Reproductive Traits in Chinese Holstein Cattle.
Liu J, Xu L, Ding X, Ma Y. Liu J, et al. Genes (Basel). 2023 Dec 20;15(1):12. doi: 10.3390/genes15010012. Genes (Basel). 2023. PMID: 38275594 Free PMC article.
We identified five genes (VWC2L, STAT1, PPP3CA, LDB3, and CTNNA3) as being associated with pregnancy ratio of young cows, five genes (PAEP, ACOXL, EPAS1, GLRB, and MARVELD1) as being associated with pregnancy ratio of adult cows, and nine genes (PDE1B, SLCO1A2, ARHGAP26, ADAM10, …
We identified five genes (VWC2L, STAT1, PPP3CA, LDB3, and CTNNA3) as being associated with pregnancy ratio of young cows, five genes (PAEP, …
Mycobacterial PknG Targets the Rab7l1 Signaling Pathway To Inhibit Phagosome-Lysosome Fusion.
Pradhan G, Shrivastva R, Mukhopadhyay S. Pradhan G, et al. J Immunol. 2018 Sep 1;201(5):1421-1433. doi: 10.4049/jimmunol.1800530. Epub 2018 Jul 23. J Immunol. 2018. PMID: 30037848
In the current study, we demonstrate that PknG of Mycobacterium sp interacts with the human Rab GTPase protein, Rab7l1, but not with other Rab proteins as well as factors like Rabaptin, Rabex5, PI3K3, Mon1a, Mon1b, early endosome autoantigen 1, and LAMP2 that are known to …
In the current study, we demonstrate that PknG of Mycobacterium sp interacts with the human Rab GTPase protein, Rab7l1, but not with other R …
Characteristics of candidate genes associated with embryonic development in the cow: Evidence for a role for WBP1 in development to the blastocyst stage.
Ortega MS, Kurian JJ, McKenna R, Hansen PJ. Ortega MS, et al. PLoS One. 2017 May 18;12(5):e0178041. doi: 10.1371/journal.pone.0178041. eCollection 2017. PLoS One. 2017. PMID: 28542629 Free PMC article.
The goal was to gain understanding of how 12 genes containing SNP previously related to embryo competence to become a blastocyst (BRINP3, C1QB, HSPA1L, IRF9, MON1B, PARM1, PCCB, PMM2, SLC18A2, TBC1D24, TTLL3 and WBP1) participate in embryonic development. ...
The goal was to gain understanding of how 12 genes containing SNP previously related to embryo competence to become a blastocyst (BRINP3, C1 …
Genetic variants in nuclear factor-kappa B binding sites are associated with clinical outcomes in prostate cancer patients.
Huang SP, Lin VC, Lee YC, Yu CC, Huang CY, Chang TY, Lee HZ, Juang SH, Lu TL, Bao BY. Huang SP, et al. Eur J Cancer. 2013 Nov;49(17):3729-37. doi: 10.1016/j.ejca.2013.07.012. Epub 2013 Aug 3. Eur J Cancer. 2013. PMID: 23920401
Four and three SNPs were notably associated with prostate cancer-specific mortality (PCSM) and all-cause mortality (ACM), respectively, after ADT. LSAMP rs13088089, CCL17 rs223899, PSMD7 rs2387084 and MON1B rs284924 remained the significant predictors for PCSM whilst PSMD7 …
Four and three SNPs were notably associated with prostate cancer-specific mortality (PCSM) and all-cause mortality (ACM), respectively, afte …
Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.
Kinchen JM, Ravichandran KS. Kinchen JM, et al. Nature. 2010 Apr 1;464(7289):778-82. doi: 10.1038/nature08853. Epub 2010 Mar 21. Nature. 2010. PMID: 20305638 Free PMC article.
In worms deficient in either sand-1 or ccz-1, apoptotic cells are internalized and the phagosomes recruit the small GTPase RAB-5 but fail to progress to the subsequent RAB-7(+) stage. The mammalian orthologues of SAND-1, namely Mon1a and Mon1b, were similarly required for …
In worms deficient in either sand-1 or ccz-1, apoptotic cells are internalized and the phagosomes recruit the small GTPase RAB-5 but fail to …
Single nucleotide polymorphisms in candidate genes associated with fertilizing ability of sperm and subsequent embryonic development in cattle.
Cochran SD, Cole JB, Null DJ, Hansen PJ. Cochran SD, et al. Biol Reprod. 2013 Sep 27;89(3):69. doi: 10.1095/biolreprod.113.111260. Print 2013 Sep. Biol Reprod. 2013. PMID: 23904513
There were nine genes with SNPs associated with CR (AVP, DEPP, EPAS1, HSD17B6, NT5E, SERPINE2, SLC18A2, TBC1D24, and a noncharacterized gene) and 12 genes with SNPs associated with BDRC (C1QB, FAM5C, HSPA1A, IRF9, MON1B, PARM1, PCCB, PMM2, SLC18A2, TBC1D24, TTLL3, and WBP1 …
There were nine genes with SNPs associated with CR (AVP, DEPP, EPAS1, HSD17B6, NT5E, SERPINE2, SLC18A2, TBC1D24, and a noncharacterized gene …
12 results