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Items: 8

1.

Discovery of novel biaryl sulfonamide based Mcl-1 inhibitors.

Follows B, Fessler S, Baumeister T, Campbell AM, Zablocki MM, Li H, Gotur D, Wang Z, Zheng X, Molz L, Nguyen C, Herbertz T, Wang L, Bair K.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2375-2382. doi: 10.1016/j.bmcl.2019.06.008. Epub 2019 Jun 11.

PMID:
31235261
2.

Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters.

Kang SA, O'Neill DJ, Machl AW, Lumpkin CJ, Galda SN, Sengupta S, Mahoney SJ, Howell JJ, Molz L, Hahm S, Vlasuk GP, Saiah E.

Cell Chem Biol. 2019 Sep 19;26(9):1203-1213.e13. doi: 10.1016/j.chembiol.2019.05.009. Epub 2019 Jun 20.

PMID:
31231029
3.

A small molecule inhibitor of Rheb selectively targets mTORC1 signaling.

Mahoney SJ, Narayan S, Molz L, Berstler LA, Kang SA, Vlasuk GP, Saiah E.

Nat Commun. 2018 Feb 7;9(1):548. doi: 10.1038/s41467-018-03035-z.

4.

MASPIT: three-hybrid trap for quantitative proteome fingerprinting of small molecule-protein interactions in mammalian cells.

Caligiuri M, Molz L, Liu Q, Kaplan F, Xu JP, Majeti JZ, Ramos-Kelsey R, Murthi K, Lievens S, Tavernier J, Kley N.

Chem Biol. 2006 Jul;13(7):711-22.

5.

Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain.

Molz L, Chen YW, Hirano M, Williams LT.

J Biol Chem. 1996 Jun 7;271(23):13892-9.

7.

Sequence elements in the Escherichia coli araFGH promoter.

Hendrickson W, Flaherty C, Molz L.

J Bacteriol. 1992 Nov;174(21):6862-71.

8.

cdc2 and the regulation of mitosis: six interacting mcs genes.

Molz L, Booher R, Young P, Beach D.

Genetics. 1989 Aug;122(4):773-82.

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