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Items: 1 to 50 of 287

1.

HIV infection compounds the lymphopenia associated with cerebral malaria in Malawian children.

Mandala WL, Gondwe EN, Nyirenda TS, Drayson M, Molyneux ME, MacLennan CA.

J Blood Med. 2018 Dec 19;10:9-18. doi: 10.2147/JBM.S187081. eCollection 2019.

2.

Peripheral blood RNA gene expression in children with pneumococcal meningitis: a prospective case-control study.

Kulohoma BW, Marriage F, Vasieva O, Mankhambo L, Nguyen K, Molyneux ME, Molyneux EM, Day PJR, Carrol ED.

BMJ Paediatr Open. 2017 Aug 31;1(1):e000092. doi: 10.1136/bmjpo-2017-000092. eCollection 2017.

3.

Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina.

Barrera V, MacCormick IJC, Czanner G, Hiscott PS, White VA, Craig AG, Beare NAV, Culshaw LH, Zheng Y, Biddolph SC, Milner DA, Kamiza S, Molyneux ME, Taylor TE, Harding SP.

Elife. 2018 Mar 26;7. pii: e32208. doi: 10.7554/eLife.32208.

4.

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4.

Gilchrist JJ, Rautanen A, Fairfax BP, Mills TC, Naranbhai V, Trochet H, Pirinen M, Muthumbi E, Mwarumba S, Njuguna P, Mturi N, Msefula CL, Gondwe EN, MacLennan JM, Chapman SJ, Molyneux ME, Knight JC, Spencer CCA, Williams TN, MacLennan CA, Scott JAG, Hill AVS.

Nat Commun. 2018 Mar 9;9(1):1014. doi: 10.1038/s41467-017-02398-z.

5.

Pathology-Based Research in Africa.

Lemos MP, Taylor TE, McGoldrick SM, Molyneux ME, Menon M, Kussick S, Mkhize NN, Martinson NA, Stritmatter A, Randolph-Habecker J.

Clin Lab Med. 2018 Mar;38(1):67-90. doi: 10.1016/j.cll.2017.10.006. Review.

6.

Presentation of life-threatening invasive nontyphoidal Salmonella disease in Malawian children: A prospective observational study.

MacLennan CA, Msefula CL, Gondwe EN, Gilchrist JJ, Pensulo P, Mandala WL, Mwimaniwa G, Banda M, Kenny J, Wilson LK, Phiri A, MacLennan JM, Molyneux EM, Molyneux ME, Graham SM.

PLoS Negl Trop Dis. 2017 Dec 7;11(12):e0006027. doi: 10.1371/journal.pntd.0006027. eCollection 2017 Dec.

7.

Age- and sex-related changes in hematological parameters in healthy Malawians.

Mandala WL, Gondwe EN, MacLennan JM, Molyneux ME, MacLennan CA.

J Blood Med. 2017 Aug 28;8:123-130. doi: 10.2147/JBM.S142189. eCollection 2017.

8.

Leukocyte counts and lymphocyte subsets in relation to pregnancy and HIV infection in Malawian women.

Mandala WL, Gondwe EN, Molyneux ME, MacLennan JM, MacLennan CA.

Am J Reprod Immunol. 2017 Sep;78(3). doi: 10.1111/aji.12678. Epub 2017 Apr 6.

9.

Cytokine Profiles in Malawian Children Presenting with Uncomplicated Malaria, Severe Malarial Anemia, and Cerebral Malaria.

Mandala WL, Msefula CL, Gondwe EN, Drayson MT, Molyneux ME, MacLennan CA.

Clin Vaccine Immunol. 2017 Apr 5;24(4). pii: e00533-16. doi: 10.1128/CVI.00533-16. Print 2017 Apr.

10.

A trial of a 7-valent pneumococcal conjugate vaccine in HIV-infected adults.

French N, Gordon SB, Mwalukomo T, White SA, Mwafulirwa G, Longwe H, Mwaiponya M, Zijlstra EE, Molyneux ME, Gilks CF.

Malawi Med J. 2016 Sep;28(3):115-122.

11.

Severe anemia in Malawian children.

Calis JC, Phiri KS, Faragher EB, Brabin BJ, Bates I, Cuevas LE, de Haan RJ, Phiri AI, Malange P, Khoka M, Hulshof PJ, van Lieshout L, Beld MG, Teo YY, Rockett KA, Richardson A, Kwiatkowski DP, Molyneux ME, van Hensbroek MB.

Malawi Med J. 2016 Sep;28(3):99-107.

12.

Bednets and malaria in Africa.

Mathanga D, Molyneux ME.

Malawi Med J. 2016 Sep;28(3):92-93. No abstract available.

13.

A medical career in Malawi - personal reflections.

Molyneux ME.

Malawi Med J. 2016 Sep;28(3):82-83. No abstract available.

14.

Cytokine Profiles during Invasive Nontyphoidal Salmonella Disease Predict Outcome in African Children.

Gilchrist JJ, Heath JN, Msefula CL, Gondwe EN, Naranbhai V, Mandala W, MacLennan JM, Molyneux EM, Graham SM, Drayson MT, Molyneux ME, MacLennan CA.

Clin Vaccine Immunol. 2016 Jul 5;23(7):601-9. doi: 10.1128/CVI.00128-16. Print 2016 Jul.

15.

Monocyte activation and cytokine production in Malawian children presenting with P. falciparum malaria.

Mandala WL, Msefula CL, Gondwe EN, Drayson MT, Molyneux ME, MacLennan CA.

Parasite Immunol. 2016 May;38(5):317-25. doi: 10.1111/pim.12319.

16.

Evidence for spleen dysfunction in malaria-HIV co-infection in a subset of pediatric patients.

Joice R, Frantzreb C, Pradham A, Seydel KB, Kamiza S, Wirth DF, Duraisingh MT, Molyneux ME, Taylor TE, Marti M, Milner DA Jr.

Mod Pathol. 2016 Apr;29(4):381-90. doi: 10.1038/modpathol.2016.27. Epub 2016 Feb 26.

17.

Author Correction for Hochman et al., Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection.

Hochman SE, Madaline TF, Wassmer SC, Mbale E, Choi N, Seydel KB, Whitten RO, Varughese J, Grau GE, Kamiza S, Molyneux ME, Taylor TE, Lee S, Milner DA Jr, Kim K.

MBio. 2016 Feb 2;7(1):e02068-15. doi: 10.1128/mBio.02068-15. No abstract available.

18.

Lymphocyte Perturbations in Malawian Children with Severe and Uncomplicated Malaria.

Mandala WL, Msefula CL, Gondwe EN, Gilchrist JJ, Graham SM, Pensulo P, Mwimaniwa G, Banda M, Taylor TE, Molyneux EE, Drayson MT, Ward SA, Molyneux ME, MacLennan CA.

Clin Vaccine Immunol. 2015 Nov 18;23(2):95-103. doi: 10.1128/CVI.00564-15.

19.

Grading fluorescein angiograms in malarial retinopathy.

MacCormick IJ, Maude RJ, Beare NA, Borooah S, Glover S, Parry D, Leach S, Molyneux ME, Dhillon B, Lewallen S, Harding SP.

Malar J. 2015 Sep 24;14:367. doi: 10.1186/s12936-015-0897-7.

20.

Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection.

Hochman SE, Madaline TF, Wassmer SC, Mbale E, Choi N, Seydel KB, Whitten RO, Varughese J, Grau GE, Kamiza S, Molyneux ME, Taylor TE, Lee S, Milner DA Jr, Kim K.

MBio. 2015 Sep 22;6(5):e01390-15. doi: 10.1128/mBio.01390-15. Erratum in: MBio. 2016;7(1):e02068-15.

21.

T-Regulatory Cells and Inflammatory and Inhibitory Cytokines in Malawian Children Residing in an Area of High and an Area of Low Malaria Transmission During Acute Uncomplicated Malaria and in Convalescence.

Nyirenda TS, Molyneux ME, Kenefeck R, Walker LS, MacLennan CA, Heyderman RS, Mandala WL.

J Pediatric Infect Dis Soc. 2015 Sep;4(3):232-41. doi: 10.1093/jpids/piu140. Epub 2015 Jan 7.

22.

Pharmacokinetics of Antituberculosis Drugs in HIV-Positive and HIV-Negative Adults in Malawi.

van Oosterhout JJ, Dzinjalamala FK, Dimba A, Waterhouse D, Davies G, Zijlstra EE, Molyneux ME, Molyneux EM, Ward S.

Antimicrob Agents Chemother. 2015 Oct;59(10):6175-80. doi: 10.1128/AAC.01193-15. Epub 2015 Jul 27.

23.

Correlation of hemorrhage, axonal damage, and blood-tissue barrier disruption in brain and retina of Malawian children with fatal cerebral malaria.

Greiner J, Dorovini-Zis K, Taylor TE, Molyneux ME, Beare NA, Kamiza S, White VA.

Front Cell Infect Microbiol. 2015 Mar 16;5:18. doi: 10.3389/fcimb.2015.00018. eCollection 2015.

24.

Quantitative Assessment of Multiorgan Sequestration of Parasites in Fatal Pediatric Cerebral Malaria.

Milner DA Jr, Lee JJ, Frantzreb C, Whitten RO, Kamiza S, Carr RA, Pradham A, Factor RE, Playforth K, Liomba G, Dzamalala C, Seydel KB, Molyneux ME, Taylor TE.

J Infect Dis. 2015 Oct 15;212(8):1317-21. doi: 10.1093/infdis/jiv205. Epub 2015 Apr 7.

25.

Brain swelling and death in children with cerebral malaria.

Seydel KB, Kampondeni SD, Valim C, Potchen MJ, Milner DA, Muwalo FW, Birbeck GL, Bradley WG, Fox LL, Glover SJ, Hammond CA, Heyderman RS, Chilingulo CA, Molyneux ME, Taylor TE.

N Engl J Med. 2015 Mar 19;372(12):1126-37. doi: 10.1056/NEJMoa1400116.

26.

The pathogenesis of pediatric cerebral malaria: eye exams, autopsies, and neuroimaging.

Taylor TE, Molyneux ME.

Ann N Y Acad Sci. 2015 Apr;1342:44-52. doi: 10.1111/nyas.12690. Epub 2015 Feb 23. Review.

27.

Differential PfEMP1 expression is associated with cerebral malaria pathology.

Tembo DL, Nyoni B, Murikoli RV, Mukaka M, Milner DA, Berriman M, Rogerson SJ, Taylor TE, Molyneux ME, Mandala WL, Craig AG, Montgomery J.

PLoS Pathog. 2014 Dec 4;10(12):e1004537. doi: 10.1371/journal.ppat.1004537. eCollection 2014 Dec.

28.

Severity of retinopathy parallels the degree of parasite sequestration in the eyes and brains of malawian children with fatal cerebral malaria.

Barrera V, Hiscott PS, Craig AG, White VA, Milner DA, Beare NA, MacCormick IJ, Kamiza S, Taylor TE, Molyneux ME, Harding SP.

J Infect Dis. 2015 Jun 15;211(12):1977-86. doi: 10.1093/infdis/jiu592. Epub 2014 Oct 28.

29.

The systemic pathology of cerebral malaria in African children.

Milner DA Jr, Whitten RO, Kamiza S, Carr R, Liomba G, Dzamalala C, Seydel KB, Molyneux ME, Taylor TE.

Front Cell Infect Microbiol. 2014 Aug 21;4:104. doi: 10.3389/fcimb.2014.00104. eCollection 2014.

30.

Control lymphocyte subsets: can one country's values serve for another's?

Mandala WL, Ananworanich J, Apornpong T, Kerr SJ, MacLennan JM, Hanson C, Jaimulwong T, Gondwe EN, Rosenblatt HM, Bunupuradah T, Molyneux ME, Spector SA, Pancharoen C, Gelman RS, MacLennan CA, Shearer WT.

J Allergy Clin Immunol. 2014 Sep;134(3):759-761.e8. doi: 10.1016/j.jaci.2014.06.030. No abstract available.

31.

Reply: Retinopathy, histidine-rich protein-2 and perfusion pressure in cerebral malaria.

MacCormick IJ, Beare NA, Taylor TE, Barrera V, White VA, Hiscott P, Molyneux ME, Dhillon B, Harding SP.

Brain. 2014 Sep;137(Pt 9):e299. doi: 10.1093/brain/awu146. Epub 2014 Jun 11. No abstract available.

32.

Decreasing malaria prevalence and its potential consequences for immunity in pregnant women.

Teo A, Hasang W, Randall LM, Feng G, Bell L, Unger H, Langer C, Beeson JG, Siba PM, Mueller I, Molyneux ME, Brown GV, Rogerson SJ.

J Infect Dis. 2014 Nov 1;210(9):1444-55. doi: 10.1093/infdis/jiu264. Epub 2014 May 5.

PMID:
24799599
33.

HIV-1 infection and antibodies to Plasmodium falciparum in adults.

Hasang W, Dembo EG, Wijesinghe R, Molyneux ME, Kublin JG, Rogerson S.

J Infect Dis. 2014 Nov 1;210(9):1407-14. doi: 10.1093/infdis/jiu262. Epub 2014 May 3.

PMID:
24795481
34.

Cerebral malaria in children: using the retina to study the brain.

MacCormick IJ, Beare NA, Taylor TE, Barrera V, White VA, Hiscott P, Molyneux ME, Dhillon B, Harding SP.

Brain. 2014 Aug;137(Pt 8):2119-42. doi: 10.1093/brain/awu001. Epub 2014 Feb 26. Review.

35.

Bacterial meningitis in Malawian adults, adolescents, and children during the era of antiretroviral scale-up and Haemophilus influenzae type b vaccination, 2000-2012.

Wall EC, Everett DB, Mukaka M, Bar-Zeev N, Feasey N, Jahn A, Moore M, van Oosterhout JJ, Pensalo P, Baguimira K, Gordon SB, Molyneux EM, Carrol ED, French N, Molyneux ME, Heyderman RS.

Clin Infect Dis. 2014 May;58(10):e137-45. doi: 10.1093/cid/ciu057. Epub 2014 Feb 4.

36.

Persistent endothelial activation and inflammation after Plasmodium falciparum Infection in Malawian children.

Moxon CA, Chisala NV, Wassmer SC, Taylor TE, Seydel KB, Molyneux ME, Faragher B, Kennedy N, Toh CH, Craig AG, Heyderman RS.

J Infect Dis. 2014 Feb 15;209(4):610-5. doi: 10.1093/infdis/jit419. Epub 2013 Sep 17.

37.

A histological method for quantifying Plasmodium falciparum in the brain in fatal paediatric cerebral malaria.

Milner DA Jr, Valim C, Carr RA, Chandak PB, Fosiko NG, Whitten R, Playforth KB, Seydel KB, Kamiza S, Molyneux ME, Taylor TE.

Malar J. 2013 Jun 7;12:191. doi: 10.1186/1475-2875-12-191.

38.

Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children.

Moxon CA, Wassmer SC, Milner DA Jr, Chisala NV, Taylor TE, Seydel KB, Molyneux ME, Faragher B, Esmon CT, Downey C, Toh CH, Craig AG, Heyderman RS.

Blood. 2013 Aug 1;122(5):842-51. doi: 10.1182/blood-2013-03-490219. Epub 2013 Jun 5.

39.

Soluble CD163, a product of monocyte/macrophage activation, is inversely associated with haemoglobin levels in placental malaria.

Chua CL, Brown GV, Hamilton JA, Molyneux ME, Rogerson SJ, Boeuf P.

PLoS One. 2013 May 22;8(5):e64127. doi: 10.1371/journal.pone.0064127. Print 2013.

40.

The alveolar microenvironment of patients infected with human immunodeficiency virus does not modify alveolar macrophage interactions with Streptococcus pneumoniae.

Gordon SB, Jagoe RT, Jarman ER, North JC, Pridmore A, Musaya J, French N, Zijlstra EE, Molyneux ME, Read RC.

Clin Vaccine Immunol. 2013 Jun;20(6):882-91. doi: 10.1128/CVI.00582-12. Epub 2013 Apr 10.

41.

Surveillance Programme of IN-patients and Epidemiology (SPINE): implementation of an electronic data collection tool within a large hospital in Malawi.

SanJoaquin MA, Allain TJ, Molyneux ME, Benjamin L, Everett DB, Gadabu O, Rothe C, Nguipdop P, Chilombe M, Kazembe L, Sakala S, Gonani A, Heyderman RS.

PLoS Med. 2013;10(3):e1001400. doi: 10.1371/journal.pmed.1001400. Epub 2013 Mar 12.

42.

Complement activation and the resulting placental vascular insufficiency drives fetal growth restriction associated with placental malaria.

Conroy AL, Silver KL, Zhong K, Rennie M, Ward P, Sarma JV, Molyneux ME, Sled J, Fletcher JF, Rogerson S, Kain KC.

Cell Host Microbe. 2013 Feb 13;13(2):215-26. doi: 10.1016/j.chom.2013.01.010.

43.

Entomological indices of malaria transmission in Chikhwawa district, Southern Malawi.

Mzilahowa T, Hastings IM, Molyneux ME, McCall PJ.

Malar J. 2012 Nov 21;11:380. doi: 10.1186/1475-2875-11-380.

44.

Prevalence of raised intracranial pressure in cerebral malaria detected by optic nerve sheath ultrasound.

Beare NA, Glover SJ, Lewallen S, Taylor TE, Harding SP, Molyneux ME.

Am J Trop Med Hyg. 2012 Dec;87(6):985-8. doi: 10.4269/ajtmh.2012.11-0459. Epub 2012 Oct 1.

45.

Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi.

Msefula CL, Kingsley RA, Gordon MA, Molyneux E, Molyneux ME, MacLennan CA, Dougan G, Heyderman RS.

PLoS One. 2012;7(7):e42085. doi: 10.1371/journal.pone.0042085. Epub 2012 Jul 27.

46.

The effects of malaria and intermittent preventive treatment during pregnancy on fetal anemia in Malawi.

Rogawski ET, Chaluluka E, Molyneux ME, Feng G, Rogerson SJ, Meshnick SR.

Clin Infect Dis. 2012 Oct;55(8):1096-102. Epub 2012 Jul 5.

PMID:
22767651
47.

Clinical manifestations of new versus recrudescent malaria infections following anti-malarial drug treatment.

Shaukat AM, Gilliams EA, Kenefic LJ, Laurens MB, Dzinjalamala FK, Nyirenda OM, Thesing PC, Jacob CG, Molyneux ME, Taylor TE, Plowe CV, Laufer MK.

Malar J. 2012 Jun 18;11:207. doi: 10.1186/1475-2875-11-207.

48.

Plasma concentrations of parasite histidine-rich protein 2 distinguish between retinopathy-positive and retinopathy-negative cerebral malaria in Malawian children.

Seydel KB, Fox LL, Glover SJ, Reeves MJ, Pensulo P, Muiruri A, Mpakiza A, Molyneux ME, Taylor TE.

J Infect Dis. 2012 Aug 1;206(3):309-18. doi: 10.1093/infdis/jis371. Epub 2012 May 25.

49.

Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children.

Irwin AD, Marriage F, Mankhambo LA; IPD Group Study, Jeffers G, Kolamunnage-Dona R, Guiver M, Denis B, Molyneux EM, Molyneux ME, Day PJ, Carrol ED.

BMC Med Genomics. 2012 May 4;5:13. doi: 10.1186/1755-8794-5-13.

50.

Acute brain MRI findings in 120 Malawian children with cerebral malaria: new insights into an ancient disease.

Potchen MJ, Kampondeni SD, Seydel KB, Birbeck GL, Hammond CA, Bradley WG, DeMarco JK, Glover SJ, Ugorji JO, Latourette MT, Siebert JE, Molyneux ME, Taylor TE.

AJNR Am J Neuroradiol. 2012 Oct;33(9):1740-6. doi: 10.3174/ajnr.A3035. Epub 2012 Apr 19.

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