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Items: 19


The immune system and psychiatric disease: a basic science perspective.

Bennett FC, Molofsky AV.

Clin Exp Immunol. 2019 Sep;197(3):294-307. doi: 10.1111/cei.13334. Epub 2019 Jun 9. Review.


Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches.

Dahlgren MW, Jones SW, Cautivo KM, Dubinin A, Ortiz-Carpena JF, Farhat S, Yu KS, Lee K, Wang C, Molofsky AV, Tward AD, Krummel MF, Peng T, Molofsky AB.

Immunity. 2019 Mar 19;50(3):707-722.e6. doi: 10.1016/j.immuni.2019.02.002. Epub 2019 Feb 26.


Demystifying Microglia: And Now the Work Begins.

Dorman LC, Molofsky AV.

Immunity. 2019 Jan 15;50(1):11-13. doi: 10.1016/j.immuni.2018.12.025.


Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes.

Kelley KW, Nakao-Inoue H, Molofsky AV, Oldham MC.

Nat Neurosci. 2018 Sep;21(9):1171-1184. doi: 10.1038/s41593-018-0216-z. Epub 2018 Aug 28.


Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength.

Kelley KW, Ben Haim L, Schirmer L, Tyzack GE, Tolman M, Miller JG, Tsai HH, Chang SM, Molofsky AV, Yang Y, Patani R, Lakatos A, Ullian EM, Rowitch DH.

Neuron. 2018 Apr 18;98(2):306-319.e7. doi: 10.1016/j.neuron.2018.03.010. Epub 2018 Apr 5.


Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.

Vainchtein ID, Chin G, Cho FS, Kelley KW, Miller JG, Chien EC, Liddelow SA, Nguyen PT, Nakao-Inoue H, Dorman LC, Akil O, Joshita S, Barres BA, Paz JT, Molofsky AB, Molofsky AV.

Science. 2018 Mar 16;359(6381):1269-1273. doi: 10.1126/science.aal3589. Epub 2018 Feb 1.


Dynamism of an Astrocyte In Vivo: Perspectives on Identity and Function.

Poskanzer KE, Molofsky AV.

Annu Rev Physiol. 2018 Feb 10;80:143-157. doi: 10.1146/annurev-physiol-021317-121125. Epub 2017 Nov 20. Review.


Astrocyte development: A Guide for the Perplexed.

Molofsky AV, Deneen B.

Glia. 2015 Aug;63(8):1320-9. doi: 10.1002/glia.22836. Epub 2015 May 12. Review.


Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.

Molofsky AV, Kelley KW, Tsai HH, Redmond SA, Chang SM, Madireddy L, Chan JR, Baranzini SE, Ullian EM, Rowitch DH.

Nature. 2014 May 8;509(7499):189-94. doi: 10.1038/nature13161. Epub 2014 Apr 28.


Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions.

Molofsky AV, Glasgow SM, Chaboub LS, Tsai HH, Murnen AT, Kelley KW, Fancy SP, Yuen TJ, Madireddy L, Baranzini S, Deneen B, Rowitch DH, Oldham MC.

Glia. 2013 Sep;61(9):1518-32. doi: 10.1002/glia.22538. Epub 2013 Jul 10.


Regional astrocyte allocation regulates CNS synaptogenesis and repair.

Tsai HH, Li H, Fuentealba LC, Molofsky AV, Taveira-Marques R, Zhuang H, Tenney A, Murnen AT, Fancy SP, Merkle F, Kessaris N, Alvarez-Buylla A, Richardson WD, Rowitch DH.

Science. 2012 Jul 20;337(6092):358-62. doi: 10.1126/science.1222381. Epub 2012 Jun 28.


Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord.

Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH.

Development. 2012 Jul;139(14):2477-87. doi: 10.1242/dev.077214. Epub 2012 Jun 6.


Astrocytes and disease: a neurodevelopmental perspective.

Molofsky AV, Krencik R, Ullian EM, Tsai HH, Deneen B, Richardson WD, Barres BA, Rowitch DH.

Genes Dev. 2012 May 1;26(9):891-907. doi: 10.1101/gad.188326.112. Review. Erratum in: Genes Dev. 2012 Jul 1;26(13):1508. Krenick, Robert [corrected to Krencik, Robert]; Ullian, Erik [corrected to Ullian, Erik M].


Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo.

He S, Iwashita T, Buchstaller J, Molofsky AV, Thomas D, Morrison SJ.

Dev Biol. 2009 Apr 15;328(2):257-72. doi: 10.1016/j.ydbio.2009.01.020. Epub 2009 Jan 27.


Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing.

Molofsky AV, Slutsky SG, Joseph NM, He S, Pardal R, Krishnamurthy J, Sharpless NE, Morrison SJ.

Nature. 2006 Sep 28;443(7110):448-52. Epub 2006 Sep 6.


Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors.

Pardal R, Molofsky AV, He S, Morrison SJ.

Cold Spring Harb Symp Quant Biol. 2005;70:177-85. Review.


Diverse mechanisms regulate stem cell self-renewal.

Molofsky AV, Pardal R, Morrison SJ.

Curr Opin Cell Biol. 2004 Dec;16(6):700-7. Review.


Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation.

Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ.

Nature. 2003 Oct 30;425(6961):962-7. Epub 2003 Oct 22.

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