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Items: 29


T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development.

de Bock CE, Down M, Baidya K, Sweron B, Boyd AW, Fiers M, Burns GF, Molloy TJ, Lock RB, Soulier J, Taghon T, Van Vlierberghe P, Cools J, Holst J, Thorne RF.

Haematologica. 2019 May;104(5):e204-e207. doi: 10.3324/haematol.2018.198424. Epub 2018 Dec 4. No abstract available.


The efficacy of antenatal steroid therapy is dependent on the duration of low-concentration fetal exposure: evidence from a sheep model of pregnancy.

Kemp MW, Saito M, Usuda H, Watanabe S, Sato S, Hanita T, Kumagai Y, Molloy TJ, Clarke M, Eddershaw PJ, Musk GC, Schmidt A, Ireland D, Furfaro L, Payne MS, Newnham JP, Jobe AH.

Am J Obstet Gynecol. 2018 Sep;219(3):301.e1-301.e16. doi: 10.1016/j.ajog.2018.05.007. Epub 2018 May 11. Erratum in: Am J Obstet Gynecol. 2019 Feb 19;:.


miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense.

Pajic M, Froio D, Daly S, Doculara L, Millar E, Graham PH, Drury A, Steinmann A, de Bock CE, Boulghourjian A, Zaratzian A, Carroll S, Toohey J, O'Toole SA, Harris AL, Buffa FM, Gee HE, Hollway GE, Molloy TJ.

Cancer Res. 2018 Jan 15;78(2):501-515. doi: 10.1158/0008-5472.CAN-16-3105. Epub 2017 Nov 27.


Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion.

Duivenvoorden HM, Rautela J, Edgington-Mitchell LE, Spurling A, Greening DW, Nowell CJ, Molloy TJ, Robbins E, Brockwell NK, Lee CS, Chen M, Holliday A, Selinger CI, Hu M, Britt KL, Stroud DA, Bogyo M, Möller A, Polyak K, Sloane BF, O'Toole SA, Parker BS.

J Pathol. 2017 Dec;243(4):496-509. doi: 10.1002/path.4990. Epub 2017 Oct 31.


Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer.

Chou A, Froio D, Nagrial AM, Parkin A, Murphy KJ, Chin VT, Wohl D, Steinmann A, Stark R, Drury A, Walters SN, Vennin C, Burgess A, Pinese M, Chantrill LA, Cowley MJ, Molloy TJ; Australian Pancreatic Cancer Genome Initiative (APGI), Waddell N, Johns A, Grimmond SM, Chang DK, Biankin AV, Sansom OJ, Morton JP, Grey ST, Cox TR, Turchini J, Samra J, Clarke SJ, Timpson P, Gill AJ, Pajic M.

Gut. 2018 Dec;67(12):2142-2155. doi: 10.1136/gutjnl-2017-315144. Epub 2017 Oct 28.


Protein interaction screening identifies SH3RF1 as a new regulator of FAT1 protein levels.

de Bock CE, Hughes MR, Snyder K, Alley S, Sadeqzadeh E, Dun MD, McNagny KM, Molloy TJ, Hondermarck H, Thorne RF.

FEBS Lett. 2017 Feb;591(4):667-678. doi: 10.1002/1873-3468.12569. Epub 2017 Feb 16.


Maternofetal pharmacokinetics and fetal lung responses in chronically catheterized sheep receiving constant, low-dose infusions of betamethasone phosphate.

Kemp MW, Saito M, Usuda H, Molloy TJ, Miura Y, Sato S, Watanabe S, Clarke M, Fossler M, Scmidt A, Kallapur SG, Kramer BW, Newnham JP, Jobe AH.

Am J Obstet Gynecol. 2016 Dec;215(6):775.e1-775.e12. doi: 10.1016/j.ajog.2016.08.017. Epub 2016 Aug 20.


Outside-in? Acute fetal systemic inflammation in very preterm chronically catheterized sheep fetuses is not driven by cells in the fetal blood.

Kemp MW, Molloy TJ, Usuda H, Woodward E, Miura Y, Payne MS, Ireland DJ, Jobe AH, Kallapur SG, Stock SJ, Spiller OB, Newnham JP, Saito M.

Am J Obstet Gynecol. 2016 Feb;214(2):281.e1-281.e10. doi: 10.1016/j.ajog.2015.09.076. Epub 2015 Sep 25.


Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma.

Oliveira CS, de Bock CE, Molloy TJ, Sadeqzadeh E, Geng XY, Hersey P, Zhang XD, Thorne RF.

BMC Cancer. 2014 Aug 29;14:630. doi: 10.1186/1471-2407-14-630.


An analysis of reported motivational orientation in students undertaking doctoral studies in the biomedical sciences.

Kemp MW, Molloy TJ, Pajic M, Chapman E.

BMC Med Educ. 2014 Feb 27;14:38. doi: 10.1186/1472-6920-14-38.


TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.

Shields BJ, Wiede F, Gurzov EN, Wee K, Hauser C, Zhu HJ, Molloy TJ, O'Toole SA, Daly RJ, Sutherland RL, Mitchell CA, McLean CA, Tiganis T.

Mol Cell Biol. 2013 Feb;33(3):557-70. doi: 10.1128/MCB.01016-12. Epub 2012 Nov 19.


Prognostic interaction between expression of p53 and estrogen receptor in patients with node-negative breast cancer: results from IBCSG Trials VIII and IX.

Coates AS, Millar EK, O'Toole SA, Molloy TJ, Viale G, Goldhirsch A, Regan MM, Gelber RD, Sun Z, Castiglione-Gertsch M, Gusterson B, Musgrove EA, Sutherland RL.

Breast Cancer Res. 2012 Nov 5;14(6):R143. doi: 10.1186/bcr3348.


A prognostic gene expression profile that predicts circulating tumor cell presence in breast cancer patients.

Molloy TJ, Roepman P, Naume B, van't Veer LJ.

PLoS One. 2012;7(2):e32426. doi: 10.1371/journal.pone.0032426. Epub 2012 Feb 23.


The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia.

de Bock CE, Ardjmand A, Molloy TJ, Bone SM, Johnstone D, Campbell DM, Shipman KL, Yeadon TM, Holst J, Spanevello MD, Nelmes G, Catchpoole DR, Lincz LF, Boyd AW, Burns GF, Thorne RF.

Leukemia. 2012 May;26(5):918-26. doi: 10.1038/leu.2011.319. Epub 2011 Nov 25.


The prognostic significance of tumour cell detection in the peripheral blood versus the bone marrow in 733 early-stage breast cancer patients.

Molloy TJ, Bosma AJ, Baumbusch LO, Synnestvedt M, Borgen E, Russnes HG, Schlichting E, van't Veer LJ, Naume B.

Breast Cancer Res. 2011 Jun 14;13(3):R61. doi: 10.1186/bcr2898.


A multimarker QPCR-based platform for the detection of circulating tumour cells in patients with early-stage breast cancer.

Molloy TJ, Devriese LA, Helgason HH, Bosma AJ, Hauptmann M, Voest EE, Schellens JH, van't Veer LJ.

Br J Cancer. 2011 Jun 7;104(12):1913-9. doi: 10.1038/bjc.2011.164. Epub 2011 May 17.


Discriminating lymphomas and reactive lymphadenopathy in lymph node biopsies by gene expression profiling.

Loi TH, Campain A, Bryant A, Molloy TJ, Lutherborrow M, Turner J, Yang YH, Ma DD.

BMC Med Genomics. 2011 Mar 31;4:27. doi: 10.1186/1755-8794-4-27.


Cytokines and apoptosis in supraspinatus tendinopathy.

Millar NL, Wei AQ, Molloy TJ, Bonar F, Murrell GA.

J Bone Joint Surg Br. 2009 Mar;91(3):417-24. doi: 10.1302/0301-620X.91B3.21652.


Heat shock protein and apoptosis in supraspinatus tendinopathy.

Millar NL, Wei AQ, Molloy TJ, Bonar F, Murrell GA.

Clin Orthop Relat Res. 2008 Jul;466(7):1569-76. doi: 10.1007/s11999-008-0265-9. Epub 2008 May 6.


Towards an optimized platform for the detection, enrichment, and semi-quantitation circulating tumor cells.

Molloy TJ, Bosma AJ, van't Veer LJ.

Breast Cancer Res Treat. 2008 Nov;112(2):297-307. doi: 10.1007/s10549-007-9872-5. Epub 2008 Jan 23.


The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.

Katsoulotos GP, Qi M, Qi JC, Tanaka K, Hughes WE, Molloy TJ, Adachi R, Stevens RL, Krilis SA.

J Biol Chem. 2008 Jan 18;283(3):1610-21. Epub 2007 Nov 16.


Inhibitors of the mevalonate pathway as potential therapeutic agents in multiple myeloma.

Baulch-Brown C, Molloy TJ, Yeh SL, Ma D, Spencer A.

Leuk Res. 2007 Mar;31(3):341-52. Epub 2006 Sep 22.


Microarray analysis of the tendinopathic rat supraspinatus tendon: glutamate signaling and its potential role in tendon degeneration.

Molloy TJ, Kemp MW, Wang Y, Murrell GA.

J Appl Physiol (1985). 2006 Dec;101(6):1702-9. Epub 2006 Aug 3.


A novel deletion mutation in keratin 5 causing the removal of 5 amino acids and elevated mutant mRNA levels in Dowling-Meara epidermolysis bullosa simplex.

Kemp MW, Klingberg S, Lloyd L, Molloy TJ, Marr P, Wang Y, Murrell GA, Murrell DF.

J Invest Dermatol. 2005 May;124(5):1083-5. No abstract available.


Percutaneous transluminal coronary angioplasty of a right coronary artery arising from the left main coronary artery.

Gibbs HH, Spokojny AM, Molloy TJ, Kamen MO, Sanborn TA.

Cathet Cardiovasc Diagn. 1993 Sep;30(1):37-9.


Electrocardiographic detection of left ventricular hypertrophy by the simple QRS voltage-duration product.

Molloy TJ, Okin PM, Devereux RB, Kligfield P.

J Am Coll Cardiol. 1992 Nov 1;20(5):1180-6.


Cocaine-induced coronary artery disease: recognition and treatment.

Frishman WH, Karpenos A, Molloy TJ.

Med Clin North Am. 1989 Mar;73(2):475-86. Review.


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