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Items: 1 to 50 of 231

1.

Protective Immunity and New Vaccines for Lyme Disease.

Gomes-Solecki M, Arnaboldi PM, Backenson PB, Benach JL, Cooper CL, Dattwyler RJ, Diuk-Wasser M, Fikrig E, Hovius JW, Laegreid W, Lundberg U, Marconi RT, Marques AR, Molloy P, Narasimhan S, Pal U, Pedra JHF, Plotkin S, Rock DL, Rosa P, Telford SR, Tsao J, Yang XF, Schutzer SE.

Clin Infect Dis. 2019 Oct 17. pii: ciz872. doi: 10.1093/cid/ciz872. [Epub ahead of print]

PMID:
31620776
2.

Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes.

Bradford ST, Nair SS, Statham AL, van Dijk SJ, Peters TJ, Anwar F, French HJ, von Martels JZH, Sutcliffe B, Maddugoda MP, Peranec M, Varinli H, Arnoldy R, Buckley M, Ross JP, Zotenko E, Song JZ, Stirzaker C, Bauer DC, Qu W, Swarbrick MM, Lutgers HL, Lord RV, Samaras K, Molloy PL, Clark SJ.

Sci Rep. 2019 Jul 2;9(1):9511. doi: 10.1038/s41598-019-45777-w.

3.

Blood Smears Have Poor Sensitivity for Confirming Borrelia miyamotoi Disease.

Telford SR, Goethert HK, Molloy PJ, Berardi V.

J Clin Microbiol. 2019 Feb 27;57(3). pii: e01468-18. doi: 10.1128/JCM.01468-18. Print 2019 Mar.

4.

Mother-child transmission of epigenetic information by tunable polymorphic imprinting.

Carpenter BL, Zhou W, Madaj Z, DeWitt AK, Ross JP, Grønbæk K, Liang G, Clark SJ, Molloy PL, Jones PA.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11970-E11977. doi: 10.1073/pnas.1815005115. Epub 2018 Dec 3.

5.

Does the McNeill Alexander model accurately predict maximum walking speed in novice and experienced race walkers?

Harrison AJ, Molloy PG, Furlong LM.

J Sport Health Sci. 2018 Jul;7(3):372-377. doi: 10.1016/j.jshs.2016.04.010. Epub 2016 May 10.

6.

Zoonotic Babesia microti in the northeastern U.S.: Evidence for the expansion of a specific parasite lineage.

Goethert HK, Molloy P, Berardi V, Weeks K, Telford SR 3rd.

PLoS One. 2018 Mar 22;13(3):e0193837. doi: 10.1371/journal.pone.0193837. eCollection 2018.

7.

Helper-Dependent Chain Reaction (HDCR) for Selective Amplification of Methylated DNA Sequences.

Mitchell SM, Rand KN, Xu ZZ, Ho T, Brown GS, Ross JP, Molloy PL.

Methods Mol Biol. 2018;1708:587-601. doi: 10.1007/978-1-4939-7481-8_30.

PMID:
29224165
8.

Seroreactivity to the C6 Peptide in Borrelia miyamotoi Infections Occurring in the Northeastern United States.

Molloy PJ, Weeks KE, Todd B, Wormser GP.

Clin Infect Dis. 2018 Apr 17;66(9):1407-1410. doi: 10.1093/cid/cix1023.

PMID:
29149281
9.

DNA methylation in blood from neonatal screening cards and the association with BMI and insulin sensitivity in early childhood.

van Dijk SJ, Peters TJ, Buckley M, Zhou J, Jones PA, Gibson RA, Makrides M, Muhlhausler BS, Molloy PL.

Int J Obes (Lond). 2018 Jan;42(1):28-35. doi: 10.1038/ijo.2017.228. Epub 2017 Sep 25.

PMID:
29064478
10.

Smoke-Induced Changes to the Epigenome Provide Fertile Ground for Oncogenic Mutation.

Clark SJ, Molloy PL.

Cancer Cell. 2017 Sep 11;32(3):278-280. doi: 10.1016/j.ccell.2017.08.016.

11.

Modulation of Hepatitis C Virus-Specific CD8 Effector T-Cell Function with Antiviral Effect in Infectious Hepatitis C Virus Coculture Model.

Ojiro K, Qu X, Cho H, Park JJ, Vuidepot A, Lissin N, Molloy PE, Bennett A, Jakobsen BK, Kaplan DE, Riley JL, Chang KM.

J Virol. 2017 Apr 28;91(10). pii: e02129-16. doi: 10.1128/JVI.02129-16. Print 2017 May 15.

12.

Spatial variation in polycyclic aromatic hydrocarbon exposure in Barrow's goldeneye (Bucephala islandica) in coastal British Columbia.

Willie M, Esler D, Boyd WS, Molloy P, Ydenberg RC.

Mar Pollut Bull. 2017 May 15;118(1-2):167-179. doi: 10.1016/j.marpolbul.2017.02.010. Epub 2017 Feb 24.

PMID:
28238486
13.

Evaluation of Methylation Biomarkers for Detection of Circulating Tumor DNA and Application to Colorectal Cancer.

Mitchell SM, Ho T, Brown GS, Baker RT, Thomas ML, McEvoy A, Xu ZZ, Ross JP, Lockett TJ, Young GP, LaPointe LC, Pedersen SK, Molloy PL.

Genes (Basel). 2016 Dec 15;7(12). pii: E125.

14.

Effect of prenatal DHA supplementation on the infant epigenome: results from a randomized controlled trial.

van Dijk SJ, Zhou J, Peters TJ, Buckley M, Sutcliffe B, Oytam Y, Gibson RA, McPhee A, Yelland LN, Makrides M, Molloy PL, Muhlhausler BS.

Clin Epigenetics. 2016 Nov 4;8:114. eCollection 2016.

15.

Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling.

Pidsley R, Zotenko E, Peters TJ, Lawrence MG, Risbridger GP, Molloy P, Van Djik S, Muhlhausler B, Stirzaker C, Clark SJ.

Genome Biol. 2016 Oct 7;17(1):208.

16.

Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors.

Yang H, Buisson S, Bossi G, Wallace Z, Hancock G, So C, Ashfield R, Vuidepot A, Mahon T, Molloy P, Oates J, Paston SJ, Aleksic M, Hassan NJ, Jakobsen BK, Dorrell L.

Mol Ther. 2016 Nov;24(11):1913-1925. doi: 10.1038/mt.2016.114. Epub 2016 Jun 6.

17.

BRAF V600E Mutant Colorectal Cancer Subtypes Based on Gene Expression.

Barras D, Missiaglia E, Wirapati P, Sieber OM, Jorissen RN, Love C, Molloy PL, Jones IT, McLaughlin S, Gibbs P, Guinney J, Simon IM, Roth AD, Bosman FT, Tejpar S, Delorenzi M.

Clin Cancer Res. 2017 Jan 1;23(1):104-115. doi: 10.1158/1078-0432.CCR-16-0140. Epub 2016 Jun 27.

18.

Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer.

Suraweera N, Mouradov D, Li S, Jorissen RN, Hampson D, Ghosh A, Sengupta N, Thaha M, Ahmed S, Kirwan M, Aleva F, Propper D, Feakins RM, Vulliamy T, Elwood NJ, Tian P, Ward RL, Hawkins NJ, Xu ZZ, Molloy PL, Jones IT, Croxford M, Gibbs P, Silver A, Sieber OM.

Oncotarget. 2016 Jun 14;7(24):36474-36488. doi: 10.18632/oncotarget.9015.

19.

Repairing Distance and Facilitating Support: Reassurance Seeking by Highly Avoidant Individuals Is Associated With Greater Closeness and Partner Support.

Girme YU, Molloy PR, Overall NC.

Pers Soc Psychol Bull. 2016 May;42(5):645-61. doi: 10.1177/0146167216637846.

PMID:
27056963
20.

Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.

Mansour S, Tocheva AS, Cave-Ayland C, Machelett MM, Sander B, Lissin NM, Molloy PE, Baird MS, Stübs G, Schröder NW, Schumann RR, Rademann J, Postle AD, Jakobsen BK, Marshall BG, Gosain R, Elkington PT, Elliott T, Skylaris CK, Essex JW, Tews I, Gadola SD.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1266-75. doi: 10.1073/pnas.1519246113. Epub 2016 Feb 16.

21.
22.

Borrelia miyamotoi.

Telford SR 3rd, Molloy PJ, Berardi VP.

Ann Intern Med. 2015 Dec 15;163(12):963-4. doi: 10.7326/L15-5187. No abstract available.

PMID:
26666794
23.

Direct intrahepatic portocaval shunt for treatment of portal thrombosis and Budd-Chiari syndrome.

Pedersen MR, Molloy P, Wood D, Seetharam A.

Ann Hepatol. 2016 Jan-Feb;15(1):127-30.

24.

Borrelia miyamotoi Disease: Neither Lyme Disease Nor Relapsing Fever.

Telford SR 3rd, Goethert HK, Molloy PJ, Berardi VP, Chowdri HR, Gugliotta JL, Lepore TJ.

Clin Lab Med. 2015 Dec;35(4):867-82. doi: 10.1016/j.cll.2015.08.002. Epub 2015 Sep 18. Review.

25.

COBRA-Seq: Sensitive and Quantitative Methylome Profiling.

Varinli H, Statham AL, Clark SJ, Molloy PL, Ross JP.

Genes (Basel). 2015 Oct 23;6(4):1140-63. doi: 10.3390/genes6041140.

26.

LipiD-QuanT: a novel method to quantify lipid accumulation in live cells.

Varinli H, Osmond-McLeod MJ, Molloy PL, Vallotton P.

J Lipid Res. 2015 Nov;56(11):2206-16. doi: 10.1194/jlr.D059758. Epub 2015 Sep 1.

27.

Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer.

Jorissen RN, Christie M, Mouradov D, Sakthianandeswaren A, Li S, Love C, Xu ZZ, Molloy PL, Jones IT, McLaughlin S, Ward RL, Hawkins NJ, Ruszkiewicz AR, Moore J, Burgess AW, Busam D, Zhao Q, Strausberg RL, Lipton L, Desai J, Gibbs P, Sieber OM.

Br J Cancer. 2015 Sep 15;113(6):979-88. doi: 10.1038/bjc.2015.296. Epub 2015 Aug 25.

28.

Borrelia miyamotoi Disease in the Northeastern United States: A Case Series.

Molloy PJ, Telford SR 3rd, Chowdri HR, Lepore TJ, Gugliotta JL, Weeks KE, Hewins ME, Goethert HK, Berardi VP.

Ann Intern Med. 2015 Jul 21;163(2):91-8. doi: 10.7326/M15-0333.

PMID:
26053877
29.

De novo identification of differentially methylated regions in the human genome.

Peters TJ, Buckley MJ, Statham AL, Pidsley R, Samaras K, V Lord R, Clark SJ, Molloy PL.

Epigenetics Chromatin. 2015 Jan 27;8:6. doi: 10.1186/1756-8935-8-6. eCollection 2015.

30.

A two-gene blood test for methylated DNA sensitive for colorectal cancer.

Pedersen SK, Baker RT, McEvoy A, Murray DH, Thomas M, Molloy PL, Mitchell S, Lockett T, Young GP, LaPointe LC.

PLoS One. 2015 Apr 30;10(4):e0125041. doi: 10.1371/journal.pone.0125041. eCollection 2015.

31.

Resistant starch alters colonic contractility and expression of related genes in rats fed a Western diet.

Patten GS, Kerr CA, Dunne RA, Shaw JM, Bird AR, Regina A, Morell MK, Lockett TJ, Molloy PL, Abeywardena MY, Topping DL, Conlon MA.

Dig Dis Sci. 2015 Jun;60(6):1624-32. doi: 10.1007/s10620-015-3537-8. Epub 2015 Jan 24.

PMID:
25616610
32.

Recent developments on the role of epigenetics in obesity and metabolic disease.

van Dijk SJ, Tellam RL, Morrison JL, Muhlhausler BS, Molloy PL.

Clin Epigenetics. 2015 Jul 11;7:66. doi: 10.1186/s13148-015-0101-5. eCollection 2015. Review.

33.

Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer.

Mahon KL, Qu W, Devaney J, Paul C, Castillo L, Wykes RJ, Chatfield MD, Boyer MJ, Stockler MR, Marx G, Gurney H, Mallesara G, Molloy PL, Horvath LG, Clark SJ; PRIMe consortium.

Br J Cancer. 2014 Oct 28;111(9):1802-9. doi: 10.1038/bjc.2014.463. Epub 2014 Aug 21.

34.

Investigational screening for Babesia microti in a large repository of blood donor samples from nonendemic and endemic areas of the United States.

Moritz ED, Winton CS, Johnson ST, Krysztof DE, Townsend RL, Foster GA, Devine P, Molloy P, Brissette E, Berardi VP, Stramer SL.

Transfusion. 2014 Sep;54(9):2226-36. doi: 10.1111/trf.12693. Epub 2014 May 28.

PMID:
24865803
35.

CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia.

Pedersen SK, Mitchell SM, Graham LD, McEvoy A, Thomas ML, Baker RT, Ross JP, Xu ZZ, Ho T, LaPointe LC, Young GP, Molloy PL.

Epigenetics. 2014 Aug;9(8):1071-82. doi: 10.4161/epi.29046. Epub 2014 May 6.

36.

Epigenetics and human obesity.

van Dijk SJ, Molloy PL, Varinli H, Morrison JL, Muhlhausler BS; Members of EpiSCOPE.

Int J Obes (Lond). 2015 Jan;39(1):85-97. doi: 10.1038/ijo.2014.34. Epub 2014 Feb 25. Review.

PMID:
24566855
37.

A panel of genes methylated with high frequency in colorectal cancer.

Mitchell SM, Ross JP, Drew HR, Ho T, Brown GS, Saunders NF, Duesing KR, Buckley MJ, Dunne R, Beetson I, Rand KN, McEvoy A, Thomas ML, Baker RT, Wattchow DA, Young GP, Lockett TJ, Pedersen SK, Lapointe LC, Molloy PL.

BMC Cancer. 2014 Jan 31;14:54. doi: 10.1186/1471-2407-14-54.

38.

Characterization and outcomes of renal leukocyte chemotactic factor 2-associated amyloidosis.

Said SM, Sethi S, Valeri AM, Chang A, Nast CC, Krahl L, Molloy P, Barry M, Fidler ME, Cornell LD, Leung N, Vrana JA, Theis JD, Dogan A, Nasr SH.

Kidney Int. 2014 Aug;86(2):370-7. doi: 10.1038/ki.2013.558. Epub 2014 Jan 22.

39.

CRNDE, a long non-coding RNA responsive to insulin/IGF signaling, regulates genes involved in central metabolism.

Ellis BC, Graham LD, Molloy PL.

Biochim Biophys Acta. 2014 Feb;1843(2):372-86. doi: 10.1016/j.bbamcr.2013.10.016. Epub 2013 Nov 1.

40.

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations.

Mouradov D, Domingo E, Gibbs P, Jorissen RN, Li S, Soo PY, Lipton L, Desai J, Danielsen HE, Oukrif D, Novelli M, Yau C, Holmes CC, Jones IT, McLaughlin S, Molloy P, Hawkins NJ, Ward R, Midgely R, Kerr D, Tomlinson IP, Sieber OM.

Am J Gastroenterol. 2013 Nov;108(11):1785-93. doi: 10.1038/ajg.2013.292. Epub 2013 Sep 17.

PMID:
24042191
41.

Borrelia miyamotoi infection presenting as human granulocytic anaplasmosis: a case report.

Chowdri HR, Gugliotta JL, Berardi VP, Goethert HK, Molloy PJ, Sterling SL, Telford SR.

Ann Intern Med. 2013 Jul 2;159(1):21-7. doi: 10.7326/0003-4819-159-1-201307020-00005.

PMID:
23817701
42.

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer.

Day FL, Jorissen RN, Lipton L, Mouradov D, Sakthianandeswaren A, Christie M, Li S, Tsui C, Tie J, Desai J, Xu ZZ, Molloy P, Whitehall V, Leggett BA, Jones IT, McLaughlin S, Ward RL, Hawkins NJ, Ruszkiewicz AR, Moore J, Busam D, Zhao Q, Strausberg RL, Gibbs P, Sieber OM.

Clin Cancer Res. 2013 Jun 15;19(12):3285-96. doi: 10.1158/1078-0432.CCR-12-3614. Epub 2013 Apr 30.

43.

An association between the PTGS2 rs5275 polymorphism and colorectal cancer risk in families with inherited non-syndromic predisposition.

Ross J, Lockett L, Brookes D, Tabor B, Duesing K, Buckley M, Lockett T, Molloy P, Macrae F, Young G, Blanco I, Capella G, Hannan GN.

Eur J Hum Genet. 2013 Dec;21(12):1389-95. doi: 10.1038/ejhg.2013.53. Epub 2013 Mar 27.

45.

CRNDE: A Long Non-Coding RNA Involved in CanceR, Neurobiology, and DEvelopment.

Ellis BC, Molloy PL, Graham LD.

Front Genet. 2012 Nov 29;3:270. doi: 10.3389/fgene.2012.00270. eCollection 2012.

46.

Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.

Domingo E, Ramamoorthy R, Oukrif D, Rosmarin D, Presz M, Wang H, Pulker H, Lockstone H, Hveem T, Cranston T, Danielsen H, Novelli M, Davidson B, Xu ZZ, Molloy P, Johnstone E, Holmes C, Midgley R, Kerr D, Sieber O, Tomlinson I.

J Pathol. 2013 Feb;229(3):441-8. doi: 10.1002/path.4139.

47.

Sensitive and selective amplification of methylated DNA sequences using helper-dependent chain reaction in combination with a methylation-dependent restriction enzymes.

Rand KN, Young GP, Ho T, Molloy PL.

Nucleic Acids Res. 2013 Jan 7;41(1):e15. doi: 10.1093/nar/gks831. Epub 2012 Sep 10.

48.

Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategies.

Aleksic M, Liddy N, Molloy PE, Pumphrey N, Vuidepot A, Chang KM, Jakobsen BK.

Eur J Immunol. 2012 Dec;42(12):3174-9. doi: 10.1002/eji.201242606. Epub 2012 Oct 16.

49.

Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa.

Liu J, Hesson LB, Meagher AP, Bourke MJ, Hawkins NJ, Rand KN, Molloy PL, Pimanda JE, Ward RL.

Cancer Prev Res (Phila). 2012 Jul;5(7):921-9. doi: 10.1158/1940-6207.CAPR-11-0577. Epub 2012 May 18.

50.

Monoclonal TCR-redirected tumor cell killing.

Liddy N, Bossi G, Adams KJ, Lissina A, Mahon TM, Hassan NJ, Gavarret J, Bianchi FC, Pumphrey NJ, Ladell K, Gostick E, Sewell AK, Lissin NM, Harwood NE, Molloy PE, Li Y, Cameron BJ, Sami M, Baston EE, Todorov PT, Paston SJ, Dennis RE, Harper JV, Dunn SM, Ashfield R, Johnson A, McGrath Y, Plesa G, June CH, Kalos M, Price DA, Vuidepot A, Williams DD, Sutton DH, Jakobsen BK.

Nat Med. 2012 Jun;18(6):980-7. doi: 10.1038/nm.2764.

PMID:
22561687

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