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Items: 1 to 50 of 495

1.

Changes in cytokines during treatment of elderly, hospitalized psychiatric patients - a naturalistic study.

Bugge E, Wynn R, Mollnes TE, Reitan SK, Lapid MI, Grønli OK.

Psychoneuroendocrinology. 2019 Jun 26;108:135-139. doi: 10.1016/j.psyneuen.2019.06.014. [Epub ahead of print]

2.

Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor.

Gravastrand CS, Steinkjer B, Halvorsen B, Landsem A, Skjelland M, Jacobsen EA, Woodruff TM, Lambris JD, Mollnes TE, Brekke OL, Espevik T, Rokstad AMA.

J Immunol. 2019 Jul 3. pii: ji1900503. doi: 10.4049/jimmunol.1900503. [Epub ahead of print]

PMID:
31270150
3.

Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency.

Macpherson ME, Halvorsen B, Yndestad A, Ueland T, Mollnes TE, Berge RK, Rashidi A, Otterdal K, Gregersen I, Kong XY, Holven KB, Aukrust P, Fevang B, Jørgensen SF.

Sci Rep. 2019 Jul 1;9(1):9427. doi: 10.1038/s41598-019-45861-1.

4.

Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis.

Dahm AEA, Jacobsen EM, Wik HS, Jacobsen AF, Mollnes TE, Kanse SM, Sandset PM.

Thromb Haemost. 2019 Jun 29. doi: 10.1055/s-0039-1692426. [Epub ahead of print]

PMID:
31254974
5.

Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model.

Pischke SE, Hestenes S, Johansen HT, Fure H, Bugge JF, Espinoza A, Skulstad H, Edvardsen T, Fosse E, Mollnes TE, Halvorsen PS, Nielsen EW.

PLoS One. 2019 Jun 27;14(6):e0218624. doi: 10.1371/journal.pone.0218624. eCollection 2019.

6.

Plasma levels of mannose-binding lectin and future risk of venous thromboembolism.

Liang RA, Høiland II, Ueland T, Aukrust P, Snir O, Hindberg K, Braekkan SK, Garred P, Mollnes TE, Hansen JB.

J Thromb Haemost. 2019 Jun 20. doi: 10.1111/jth.14539. [Epub ahead of print]

PMID:
31220397
7.

Biphasic Release of the Alarmin High Mobility Group Box 1 Protein Early After Trauma Predicts Poor Clinical Outcome.

Ottestad W, Rognes IN, Pischke SE, Mollnes TE, Andersson U, Eken T.

Crit Care Med. 2019 Aug;47(8):e614-e622. doi: 10.1097/CCM.0000000000003800.

PMID:
31162203
8.

Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14.

Skjeflo EW, Christiansen D, Landsem A, Stenvik J, Woodruff TM, Espevik T, Nielsen EW, Mollnes TE.

Mol Immunol. 2019 May 15;112:131-139. doi: 10.1016/j.molimm.2019.03.014. [Epub ahead of print]

9.

Complement activation assessed by the plasma terminal complement complex and future risk of venous thromboembolism.

Høiland II, Liang RA, Braekkan SK, Pettersen K, Ludviksen JK, Latysheva N, Snir O, Ueland T, Hindberg K, Mollnes TE, Hansen JB.

J Thromb Haemost. 2019 Jun;17(6):934-943. doi: 10.1111/jth.14438. Epub 2019 May 13.

PMID:
30920726
10.

The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model.

Granslo HN, Aarag Fredheim EG, Esaiassen E, Christophersen L, Jensen PØ, Mollnes TE, Moser C, Flaegstad T, Klingenberg C, Cavanagh JP.

APMIS. 2019 Jun;127(6):475-483. doi: 10.1111/apm.12946. Epub 2019 Apr 26.

PMID:
30916807
11.

Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: results of a 5-year follow-up cohort study.

Siljan WW, Holter JC, Michelsen AE, Nymo SH, Lauritzen T, Oppen K, Husebye E, Ueland T, Mollnes TE, Aukrust P, Heggelund L.

ERJ Open Res. 2019 Mar 11;5(1). pii: 00014-2019. doi: 10.1183/23120541.00014-2019. eCollection 2019 Feb.

12.

Clinical and Complement Long-Term Follow-Up of a Pediatric Patient with C3 Mutation-Related Atypical Hemolytic Uremic Syndrome.

Bjerre A, Bergseth G, Ludviksen JK, Stokke A, Bosnes V, Karpman D, Mollnes TE.

Case Rep Nephrol. 2018 Dec 18;2018:3810249. doi: 10.1155/2018/3810249. eCollection 2018.

13.

Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency.

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B.

Sci Rep. 2019 Jan 17;9(1):167. doi: 10.1038/s41598-018-35367-7.

14.

The Role of Complement in Liver Injury, Regeneration, and Transplantation.

Thorgersen EB, Barratt-Due A, Haugaa H, Harboe M, Pischke SE, Nilsson PH, Mollnes TE.

Hepatology. 2019 Jan 17. doi: 10.1002/hep.30508. [Epub ahead of print] Review.

PMID:
30653682
15.

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.

Gaya da Costa M, Poppelaars F, van Kooten C, Mollnes TE, Tedesco F, Würzner R, Trouw LA, Truedsson L, Daha MR, Roos A, Seelen MA.

Front Immunol. 2018 Nov 20;9:2664. doi: 10.3389/fimmu.2018.02664. eCollection 2018.

16.

High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections.

Quist-Paulsen E, Aukrust P, Kran AB, Dunlop O, Ormaasen V, Stiksrud B, Midttun Ø, Ueland T, Ueland PM, Mollnes TE, Dyrhol-Riise AM.

J Neuroinflammation. 2018 Nov 23;15(1):327. doi: 10.1186/s12974-018-1366-3.

17.

Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4.

Landsem A, Fure H, Krey Ludviksen J, Christiansen D, Lau C, Mathisen M, Bergseth G, Nymo S, Lappegård KT, Woodruff TM, Espevik T, Mollnes TE, Brekke OL.

Clin Exp Immunol. 2019 Apr;196(1):97-110. doi: 10.1111/cei.13240. Epub 2018 Dec 19.

18.

C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release.

Skovdahl HK, Damås JK, Granlund AVB, Østvik AE, Doseth B, Bruland T, Mollnes TE, Sandvik AK.

Int J Mol Sci. 2018 Oct 20;19(10). pii: E3257. doi: 10.3390/ijms19103257.

19.

The Palliative Radiotherapy and Inflammation Study (PRAIS) - protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain.

Habberstad R, Frøseth TCS, Aass N, Abramova T, Baas T, Mørkeset ST, Caraceni A, Laird B, Boland JW, Rossi R, Garcia-Alonso E, Stensheim H, Loge JH, Hjermstad MJ, Bjerkeset E, Bye A, Lund JÅ, Solheim TS, Vagnildhaug OM, Brunelli C, Damås JK, Mollnes TE, Kaasa S, Klepstad P.

BMC Palliat Care. 2018 Sep 28;17(1):110. doi: 10.1186/s12904-018-0362-9.

20.

Cytokine profiles and diagnoses in elderly, hospitalized psychiatric patients.

Bugge E, Wynn R, Mollnes TE, Reitan SK, Grønli OK.

BMC Psychiatry. 2018 Sep 27;18(1):315. doi: 10.1186/s12888-018-1900-y.

21.

IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction.

Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE.

Front Immunol. 2018 Sep 12;9:2035. doi: 10.3389/fimmu.2018.02035. eCollection 2018.

22.

Cytokine profiling and post-transfusion haemoglobin increment in patients with haematological diseases.

Wendelbo Ø, Opheim EN, Hervig T, Felli Lunde TH, Bruserud Ø, Mollnes TE, Reikvam H.

Vox Sang. 2018 Oct;113(7):657-668. doi: 10.1111/vox.12703. Epub 2018 Aug 29.

PMID:
30159896
23.

Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood.

Wolf-Grosse S, Mollnes TE, Ali S, Stenvik J, Nilsen AM.

Nanomedicine (Lond). 2018 Aug 7. doi: 10.2217/nnm-2017-0362. [Epub ahead of print]

PMID:
30084726
24.

Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism.

Høiland II, Liang RA, Hindberg K, Latysheva N, Brekke OL, Mollnes TE, Hansen JB.

Thromb Res. 2018 Sep;169:50-56. doi: 10.1016/j.thromres.2018.06.019. Epub 2018 Jun 30.

25.

Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction.

Kleveland O, Ueland T, Kunszt G, Bratlie M, Yndestad A, Broch K, Holte E, Ryan L, Amundsen BH, Bendz B, Aakhus S, Espevik T, Halvorsen B, Mollnes TE, Wiseth R, Gullestad L, Aukrust P, Damås JK.

Int J Cardiol. 2018 Nov 15;271:1-7. doi: 10.1016/j.ijcard.2018.04.136. Epub 2018 Jun 29.

PMID:
29961572
26.

Exploration of 27 plasma immune markers: a cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons.

Gaarden TL, Engedal K, Benth JŠ, Larsen M, Lorentzen B, Mollnes TE, Bjølseth TM, Castellheim A.

BMC Geriatr. 2018 Jun 25;18(1):149. doi: 10.1186/s12877-018-0836-x.

27.

Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction.

Orrem HL, Shetelig C, Ueland T, Limalanathan S, Nilsson PH, Husebye T, Aukrust P, Seljeflot I, Hoffmann P, Eritsland J, Mollnes TE, Andersen GØ, Yndestad A.

Int J Cardiol. 2018 Oct 1;268:187-192. doi: 10.1016/j.ijcard.2018.05.032. Epub 2018 May 28.

PMID:
29853279
28.

Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation.

Skaare H, Svensson M, Jenssen T, Åsberg A, Schmidt EB, Chandra A, Ueland T, Mollnes TE, Hartmann A, Eide IA.

J Ren Nutr. 2018 Sep;28(5):333-339. doi: 10.1053/j.jrn.2018.02.008. Epub 2018 Apr 24.

PMID:
29703632
29.

Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) - an ex vivo study with blood from a C5-deficient individual.

Hardersen R, Enebakk T, Christiansen D, Bergseth G, Brekke OL, Mollnes TE, Lappegård KT, Hovland A.

APMIS. 2018 Apr;126(4):342-352. doi: 10.1111/apm.12821.

PMID:
29575196
30.

Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models.

Askarian F, Lapek JD Jr, Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M.

Front Microbiol. 2018 Feb 20;9:262. doi: 10.3389/fmicb.2018.00262. eCollection 2018.

31.

Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome.

Thomas AM, Schjalm C, Nilsson PH, Lindenskov PHH, Rørtveit R, Solberg R, Saugstad OD, Berglund MM, Strömberg P, Lau C, Espevik T, Jansen JH, Castellheim A, Mollnes TE, Barratt-Due A.

Neonatology. 2018;113(4):322-330. doi: 10.1159/000486542. Epub 2018 Feb 27.

32.

Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation.

Skjeflo EW, Christiansen D, Fure H, Ludviksen JK, Woodruff TM, Espevik T, Nielsen EW, Brekke OL, Mollnes TE.

J Thromb Haemost. 2018 May;16(5):905-918. doi: 10.1111/jth.13979. Epub 2018 Mar 23.

PMID:
29437288
33.

Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock.

Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE.

ESC Heart Fail. 2018 Jun;5(3):292-301. doi: 10.1002/ehf2.12266. Epub 2018 Feb 9.

34.

Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia.

Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Skattum L, Bosnes V, Garred P, Frøland SS, Mollnes TE, Aukrust P, Heggelund L.

Open Forum Infect Dis. 2018 Jan 5;5(2):ofy002. doi: 10.1093/ofid/ofy002. eCollection 2018 Feb.

35.

Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study.

Langeland H, Bergum D, Løberg M, Bjørnstad K, Damås JK, Mollnes TE, Skjærvold NK, Klepstad P.

JMIR Res Protoc. 2018 Jan 19;7(1):e17. doi: 10.2196/resprot.8558.

36.

Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement.

Fiane KKH, Dahle G, Bendz B, Halvorsen PS, Abdelnoor M, Mollnes TE, Fosse E.

Scand Cardiovasc J. 2018 Feb;52(1):43-50. doi: 10.1080/14017431.2017.1416157. Epub 2017 Dec 12.

PMID:
29233022
37.

Transforming growth factor beta (TGF-β) in adolescent chronic fatigue syndrome.

Wyller VB, Nguyen CB, Ludviksen JA, Mollnes TE.

J Transl Med. 2017 Dec 4;15(1):245. doi: 10.1186/s12967-017-1350-1.

38.

Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia.

Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Aukrust P, Mollnes TE, Heggelund L.

Eur J Clin Invest. 2018 Jan;48(1). doi: 10.1111/eci.12865. Epub 2017 Dec 7.

39.

Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.

Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Damås JK, Mollnes TE, Espevik T.

J Immunol. 2017 Oct 15;199(8):2910-2920. doi: 10.4049/jimmunol.1700302. Epub 2017 Aug 30.

40.

Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy.

Paunas TIF, Finne K, Leh S, Marti HP, Mollnes TE, Berven F, Vikse BE.

Clin Proteomics. 2017 Aug 14;14:30. doi: 10.1186/s12014-017-9165-x. eCollection 2017.

41.

Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis.

Keshari RS, Silasi R, Popescu NI, Patel MM, Chaaban H, Lupu C, Coggeshall KM, Mollnes TE, DeMarco SJ, Lupu F.

Proc Natl Acad Sci U S A. 2017 Jul 18. pii: 201706818. doi: 10.1073/pnas.1706818114. [Epub ahead of print]

42.

Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses.

Nilsson PH, Thomas AM, Bergseth G, Gustavsen A, Volokhina EB, van den Heuvel LP, Barratt-Due A, Mollnes TE.

Mol Immunol. 2017 Sep;89:111-114. doi: 10.1016/j.molimm.2017.05.021. Epub 2017 Jun 10.

43.

Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines - Consequences for defining reference values in healthy humans.

Hennø LT, Storjord E, Christiansen D, Bergseth G, Ludviksen JK, Fure H, Barene S, Nielsen EW, Mollnes TE, Brekke OL.

Cytokine. 2017 Sep;97:86-95. doi: 10.1016/j.cyto.2017.05.014. Epub 2017 Jun 6.

PMID:
28595117
44.

Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model.

Wolf-Grosse S, Rokstad AM, Ali S, Lambris JD, Mollnes TE, Nilsen AM, Stenvik J.

Int J Nanomedicine. 2017 May 23;12:3927-3940. doi: 10.2147/IJN.S136453. eCollection 2017.

45.

Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII.

Gravastrand C, Hamad S, Fure H, Steinkjer B, Ryan L, Oberholzer J, Lambris JD, Lacík I, Mollnes TE, Espevik T, Brekke OL, Rokstad AM.

Acta Biomater. 2017 Aug;58:158-167. doi: 10.1016/j.actbio.2017.05.052. Epub 2017 May 30.

46.

Complement in clinical medicine: Clinical trials, case reports and therapy monitoring.

Ricklin D, Barratt-Due A, Mollnes TE.

Mol Immunol. 2017 Sep;89:10-21. doi: 10.1016/j.molimm.2017.05.013. Epub 2017 May 31. Review.

47.

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes.

Wibroe PP, Anselmo AC, Nilsson PH, Sarode A, Gupta V, Urbanics R, Szebeni J, Hunter AC, Mitragotri S, Mollnes TE, Moghimi SM.

Nat Nanotechnol. 2017 Jul;12(6):589-594. doi: 10.1038/nnano.2017.47. Epub 2017 Apr 10.

PMID:
28396605
48.

Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases.

Shields KJ, Mollnes TE, Eidet JR, Mikkelsen K, Almdahl SM, Bottazzi B, Lyberg T, Manzi S, Ahearn JM, Hollan I.

PLoS One. 2017 Mar 31;12(3):e0174577. doi: 10.1371/journal.pone.0174577. eCollection 2017.

49.

Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: A case report.

Gustavsen A, Skattum L, Bergseth G, Lorentzen B, Floisand Y, Bosnes V, Mollnes TE, Barratt-Due A.

Medicine (Baltimore). 2017 Mar;96(11):e6338. doi: 10.1097/MD.0000000000006338.

50.

Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis.

Hellerud BC, Orrem HL, Dybwik K, Pischke SE, Baratt-Due A, Castellheim A, Fure H, Bergseth G, Christiansen D, Nunn MA, Espevik T, Lau C, Brandtzæg P, Nielsen EW, Mollnes TE.

J Intensive Care. 2017 Feb 27;5:21. doi: 10.1186/s40560-017-0217-0. eCollection 2017.

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