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Items: 16


Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation.

Shang W, Jiang Y, Boettcher M, Ding K, Mollenauer M, Liu Z, Wen X, Liu C, Hao P, Zhao S, McManus MT, Wei L, Weiss A, Wang H.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4051-E4060. doi: 10.1073/pnas.1801340115. Epub 2018 Apr 9.


A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45.

Courtney AH, Amacher JF, Kadlecek TA, Mollenauer MN, Au-Yeung BB, Kuriyan J, Weiss A.

Mol Cell. 2017 Aug 3;67(3):498-511.e6. doi: 10.1016/j.molcel.2017.06.024. Epub 2017 Jul 20.


Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor.

Tian R, Wang H, Gish GD, Petsalaki E, Pasculescu A, Shi Y, Mollenauer M, Bagshaw RD, Yosef N, Hunter T, Gingras AC, Weiss A, Pawson T.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1594-603. doi: 10.1073/pnas.1503286112. Epub 2015 Mar 17.


Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation.

Punwani D, Wang H, Chan AY, Cowan MJ, Mallott J, Sunderam U, Mollenauer M, Srinivasan R, Brenner SE, Mulder A, Claas FH, Weiss A, Puck JM.

J Clin Immunol. 2015 Feb;35(2):135-46. doi: 10.1007/s10875-014-0125-1. Epub 2015 Jan 28.


Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.

Phee H, Au-Yeung BB, Pryshchep O, O'Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A.

Elife. 2014 May 13;3:e02270. doi: 10.7554/eLife.02270.


Regulation of thymocyte positive selection and motility by GIT2.

Phee H, Dzhagalov I, Mollenauer M, Wang Y, Irvine DJ, Robey E, Weiss A.

Nat Immunol. 2010 Jun;11(6):503-11. doi: 10.1038/ni.1868. Epub 2010 May 2.


Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes.

Roose JP, Mollenauer M, Ho M, Kurosaki T, Weiss A.

Mol Cell Biol. 2007 Apr;27(7):2732-45. Epub 2007 Feb 5.


A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.

Roose JP, Mollenauer M, Gupta VA, Stone J, Weiss A.

Mol Cell Biol. 2005 Jun;25(11):4426-41.


Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec.

Tomlinson MG, Kane LP, Su J, Kadlecek TA, Mollenauer MN, Weiss A.

Mol Cell Biol. 2004 Mar;24(6):2455-66.


Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription.

Kane LP, Mollenauer MN, Xu Z, Turck CW, Weiss A.

Mol Cell Biol. 2002 Aug;22(16):5962-74.


c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1.

Shapiro VS, Mollenauer MN, Greene WC, Weiss A.

J Exp Med. 1996 Nov 1;184(5):1663-9.


Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling.

Qian D, Mollenauer MN, Weiss A.

J Exp Med. 1996 Feb 1;183(2):611-20.

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