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Items: 49

1.

Genetically Encoded Libraries of Constrained Peptides.

Bosma T, Rink R, Moosmeier MA, Moll GN.

Chembiochem. 2019 Jul 15;20(14):1754-1758. doi: 10.1002/cbic.201900031. Epub 2019 May 28. Review.

PMID:
30794341
2.

Efficacy of lanthionine-stabilized angiotensin-(1-7) in type I and type II diabetes mouse models.

Kuipers A, Moll GN, Wagner E, Franklin R.

Peptides. 2019 Feb;112:78-84. doi: 10.1016/j.peptides.2018.10.015. Epub 2018 Dec 4.

PMID:
30529303
3.

Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein.

Urban JH, Moosmeier MA, Aumüller T, Thein M, Bosma T, Rink R, Groth K, Zulley M, Siegers K, Tissot K, Moll GN, Prassler J.

Nat Commun. 2017 Nov 15;8(1):1500. doi: 10.1038/s41467-017-01413-7.

4.

Semi-microbiological synthesis of an active lysinoalanine-bridged analog of glucagon-like-peptide-1.

Kuipers A, de Vries L, de Vries MP, Rink R, Bosma T, Moll GN.

Peptides. 2017 May;91:33-39. doi: 10.1016/j.peptides.2017.03.004. Epub 2017 Mar 12.

PMID:
28300673
5.

Mutagenesis of nisin's leader peptide proline strongly modulates export of precursor nisin.

Plat A, Kuipers A, Crabb J, Rink R, Moll GN.

Antonie Van Leeuwenhoek. 2017 Mar;110(3):321-330. doi: 10.1007/s10482-016-0802-6. Epub 2016 Nov 10.

PMID:
27830473
6.

Discovery, Production and Modification of Five Novel Lantibiotics Using the Promiscuous Nisin Modification Machinery.

van Heel AJ, Kloosterman TG, Montalban-Lopez M, Deng J, Plat A, Baudu B, Hendriks D, Moll GN, Kuipers OP.

ACS Synth Biol. 2016 Oct 21;5(10):1146-1154. Epub 2016 Jul 7.

PMID:
27294279
7.

GRPR-selective PET imaging of prostate cancer using [(18)F]-lanthionine-bombesin analogs.

Carlucci G, Kuipers A, Ananias HJ, de Paula Faria D, Dierckx RA, Helfrich W, Rink R, Moll GN, de Jong IJ, Elsinga PH.

Peptides. 2015 May;67:45-54. doi: 10.1016/j.peptides.2015.03.004. Epub 2015 Mar 20.

PMID:
25797109
8.

Identification of essential amino acid residues in the nisin dehydratase NisB.

Khusainov R, van Heel AJ, Lubelski J, Moll GN, Kuipers OP.

Front Microbiol. 2015 Feb 26;6:102. doi: 10.3389/fmicb.2015.00102. eCollection 2015.

9.

Identification of distinct nisin leader peptide regions that determine interactions with the modification enzymes NisB and NisC.

Khusainov R, Moll GN, Kuipers OP.

FEBS Open Bio. 2013 May 30;3:237-42. doi: 10.1016/j.fob.2013.05.001. Print 2013.

10.

Mechanistic aspects of lanthipeptide leaders.

Plat A, Kuipers A, Rink R, Moll GN.

Curr Protein Pept Sci. 2013 Mar;14(2):85-96. Review.

PMID:
23441895
11.

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian KD, Fischbach MA, Garavelli JS, Göransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Müller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJ, Rebuffat S, Ross RP, Sahl HG, Schmidt EW, Selsted ME, Severinov K, Shen B, Sivonen K, Smith L, Stein T, Süssmuth RD, Tagg JR, Tang GL, Truman AW, Vederas JC, Walsh CT, Walton JD, Wenzel SC, Willey JM, van der Donk WA.

Nat Prod Rep. 2013 Jan;30(1):108-60. doi: 10.1039/c2np20085f. Review.

12.

Determining sites of interaction between prenisin and its modification enzymes NisB and NisC.

Khusainov R, Heils R, Lubelski J, Moll GN, Kuipers OP.

Mol Microbiol. 2011 Nov;82(3):706-18. doi: 10.1111/j.1365-2958.2011.07846.x.

13.

Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist.

Wösten-van Asperen RM, Lutter R, Specht PA, Moll GN, van Woensel JB, van der Loos CM, van Goor H, Kamilic J, Florquin S, Bos AP.

J Pathol. 2011 Dec;225(4):618-27. doi: 10.1002/path.2987. Epub 2011 Oct 18.

PMID:
22009550
14.

Bacterial display and screening of posttranslationally thioether-stabilized peptides.

Bosma T, Kuipers A, Bulten E, de Vries L, Rink R, Moll GN.

Appl Environ Microbiol. 2011 Oct;77(19):6794-801. doi: 10.1128/AEM.05550-11. Epub 2011 Aug 5.

15.

Substrate recognition and specificity of the NisB protein, the lantibiotic dehydratase involved in nisin biosynthesis.

Mavaro A, Abts A, Bakkes PJ, Moll GN, Driessen AJ, Smits SH, Schmitt L.

J Biol Chem. 2011 Sep 2;286(35):30552-60. doi: 10.1074/jbc.M111.263210. Epub 2011 Jul 8.

16.

Requirements of the engineered leader peptide of nisin for inducing modification, export, and cleavage.

Plat A, Kluskens LD, Kuipers A, Rink R, Moll GN.

Appl Environ Microbiol. 2011 Jan;77(2):604-11. doi: 10.1128/AEM.01503-10. Epub 2010 Nov 19.

17.

Oral and pulmonary delivery of thioether-bridged angiotensin-(1-7).

de Vries L, Reitzema-Klein CE, Meter-Arkema A, van Dam A, Rink R, Moll GN, Akanbi MH.

Peptides. 2010 May;31(5):893-8. doi: 10.1016/j.peptides.2010.02.015. Epub 2010 Mar 3.

PMID:
20206220
18.

To protect peptide pharmaceuticals against peptidases.

Rink R, Arkema-Meter A, Baudoin I, Post E, Kuipers A, Nelemans SA, Akanbi MH, Moll GN.

J Pharmacol Toxicol Methods. 2010 Mar-Apr;61(2):210-8. doi: 10.1016/j.vascn.2010.02.010. Epub 2010 Feb 20.

PMID:
20176117
19.

Microbial engineering of dehydro-amino acids and lanthionines in non-lantibiotic peptides.

Moll GN, Kuipers A, Rink R.

Antonie Van Leeuwenhoek. 2010 May;97(4):319-33. doi: 10.1007/s10482-010-9418-4. Epub 2010 Feb 6. Review.

PMID:
20140513
20.

Production of a class II two-component lantibiotic of Streptococcus pneumoniae using the class I nisin synthetic machinery and leader sequence.

Majchrzykiewicz JA, Lubelski J, Moll GN, Kuipers A, Bijlsma JJ, Kuipers OP, Rink R.

Antimicrob Agents Chemother. 2010 Apr;54(4):1498-505. doi: 10.1128/AAC.00883-09. Epub 2010 Jan 25.

21.

Translocation of a thioether-bridged azurin peptide fragment via the sec pathway in Lactococcus lactis.

Kuipers A, Rink R, Moll GN.

Appl Environ Microbiol. 2009 Jun;75(11):3800-2. doi: 10.1128/AEM.00341-09. Epub 2009 Mar 27.

22.

Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog.

Kluskens LD, Nelemans SA, Rink R, de Vries L, Meter-Arkema A, Wang Y, Walther T, Kuipers A, Moll GN, Haas M.

J Pharmacol Exp Ther. 2009 Mar;328(3):849-54. doi: 10.1124/jpet.108.146431. Epub 2008 Nov 26.

PMID:
19038778
23.

Mechanistic dissection of the enzyme complexes involved in biosynthesis of lacticin 3147 and nisin.

Kuipers A, Meijer-Wierenga J, Rink R, Kluskens LD, Moll GN.

Appl Environ Microbiol. 2008 Nov;74(21):6591-7. doi: 10.1128/AEM.01334-08. Epub 2008 Sep 12.

24.

Distinct contributions of the nisin biosynthesis enzymes NisB and NisC and transporter NisT to prenisin production by Lactococcus lactis.

van den Berg van Saparoea HB, Bakkes PJ, Moll GN, Driessen AJ.

Appl Environ Microbiol. 2008 Sep;74(17):5541-8. doi: 10.1128/AEM.00342-08. Epub 2008 Jul 11.

25.

Influence of shifting positions of Ser, Thr, and Cys residues in prenisin on the efficiency of modification reactions and on the antimicrobial activities of the modified prepeptides.

Lubelski J, Overkamp W, Kluskens LD, Moll GN, Kuipers OP.

Appl Environ Microbiol. 2008 Aug;74(15):4680-5. doi: 10.1128/AEM.00112-08. Epub 2008 Jun 6.

26.

Biosynthesis, immunity, regulation, mode of action and engineering of the model lantibiotic nisin.

Lubelski J, Rink R, Khusainov R, Moll GN, Kuipers OP.

Cell Mol Life Sci. 2008 Feb;65(3):455-76. Review.

PMID:
17965835
27.

NisC, the cyclase of the lantibiotic nisin, can catalyze cyclization of designed nonlantibiotic peptides.

Rink R, Kluskens LD, Kuipers A, Driessen AJ, Kuipers OP, Moll GN.

Biochemistry. 2007 Nov 13;46(45):13179-89. Epub 2007 Oct 12.

PMID:
17929939
28.

Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation.

Rink R, Wierenga J, Kuipers A, Kluskens LD, Driessen AJ, Kuipers OP, Moll GN.

Appl Environ Microbiol. 2007 Sep;73(18):5809-16. Epub 2007 Jul 27.

29.

Production of dehydroamino acid-containing peptides by Lactococcus lactis.

Rink R, Wierenga J, Kuipers A, Kluskens LD, Driessen AJ, Kuipers OP, Moll GN.

Appl Environ Microbiol. 2007 Mar;73(6):1792-6. Epub 2007 Jan 19.

30.

Sec-mediated transport of posttranslationally dehydrated peptides in Lactococcus lactis.

Kuipers A, Wierenga J, Rink R, Kluskens LD, Driessen AJ, Kuipers OP, Moll GN.

Appl Environ Microbiol. 2006 Dec;72(12):7626-33. Epub 2006 Oct 13.

31.

Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis.

Li B, Yu JP, Brunzelle JS, Moll GN, van der Donk WA, Nair SK.

Science. 2006 Mar 10;311(5766):1464-7.

32.

Post-translational modification of therapeutic peptides by NisB, the dehydratase of the lantibiotic nisin.

Kluskens LD, Kuipers A, Rink R, de Boef E, Fekken S, Driessen AJ, Kuipers OP, Moll GN.

Biochemistry. 2005 Sep 27;44(38):12827-34.

PMID:
16171398
33.

Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes.

Rink R, Kuipers A, de Boef E, Leenhouts KJ, Driessen AJ, Moll GN, Kuipers OP.

Biochemistry. 2005 Jun 21;44(24):8873-82.

PMID:
15952794
34.

NisT, the transporter of the lantibiotic nisin, can transport fully modified, dehydrated, and unmodified prenisin and fusions of the leader peptide with non-lantibiotic peptides.

Kuipers A, de Boef E, Rink R, Fekken S, Kluskens LD, Driessen AJ, Leenhouts K, Kuipers OP, Moll GN.

J Biol Chem. 2004 May 21;279(21):22176-82. Epub 2004 Mar 24.

35.

Enterocin P causes potassium ion efflux from Enterococcus faecium T136 cells.

Herranz C, Cintas LM, Hernández PE, Moll GN, Driessen AJ.

Antimicrob Agents Chemother. 2001 Mar;45(3):901-4.

36.

Comparison of the membrane interaction and permeabilization by the designed peptide Ac-MB21-NH2 and truncated dermaseptin S3.

Moll GN, Brul S, Konings WN, Driessen AJ.

Biochemistry. 2000 Oct 3;39(39):11907-12.

PMID:
11009603
37.

Bacteriocins: mechanism of membrane insertion and pore formation.

Moll GN, Konings WN, Driessen AJ.

Antonie Van Leeuwenhoek. 1999 Jul-Nov;76(1-4):185-98. Review.

PMID:
10532378
38.

Complementary and overlapping selectivity of the two-peptide bacteriocins plantaricin EF and JK.

Moll GN, van den Akker E, Hauge HH, Nissen-Meyer J, Nes IF, Konings WN, Driessen AJ.

J Bacteriol. 1999 Aug;181(16):4848-52.

39.

The lantibiotic nisin induces transmembrane movement of a fluorescent phospholipid.

Moll GN, Konings WN, Driessen AJ.

J Bacteriol. 1998 Dec;180(24):6565-70.

40.

Plantaricin A is an amphiphilic alpha-helical bacteriocin-like pheromone which exerts antimicrobial and pheromone activities through different mechanisms.

Hauge HH, Mantzilas D, Moll GN, Konings WN, Driessen AJ, Eijsink VG, Nissen-Meyer J.

Biochemistry. 1998 Nov 17;37(46):16026-32.

PMID:
9819195
41.

Role of transmembrane pH gradient and membrane binding in nisin pore formation.

Moll GN, Clark J, Chan WC, Bycroft BW, Roberts GC, Konings WN, Driessen AJ.

J Bacteriol. 1997 Jan;179(1):135-40.

42.

Mechanism of lantibiotic-induced pore-formation.

Moll GN, Roberts GC, Konings WN, Driessen AJ.

Antonie Van Leeuwenhoek. 1996 Feb;69(2):185-91. Review.

PMID:
8775978
43.

Indirect introduction of long-chain pyrene-phosphatidylcholine into living cells.

Moll GN, el Yandouzi EH, Zlatkine P, Le Grimellec C.

Anal Biochem. 1994 Sep;221(2):420-2. No abstract available.

PMID:
7810890
44.

Selective internalization of choline-phospholipids in Plasmodium falciparum parasitized human erythrocytes.

Simões AP, Moll GN, Slotboom AJ, Roelofsen B, Op den Kamp JA.

Biochim Biophys Acta. 1991 Mar 18;1063(1):45-50.

PMID:
2015260
45.

Growth inhibition of Plasmodium falciparum in in vitro cultures by selective action of tryptophan-N-formylated gramicidin incorporated in lipid vesicles.

Moll GN, van den Eertwegh V, Tournois H, Roelofsen B, Op den Kamp JA, van Deenen LL.

Biochim Biophys Acta. 1991 Feb 25;1062(2):206-10.

PMID:
1706202
46.

Selective elimination of malaria infected erythrocytes by a modified phospholipase A2 in vitro.

Moll GN, Vial HJ, van der Wiele FC, Ancelin ML, Roelofsen B, Slotboom AJ, de Haas GH, van Deenen LL, Op den Kamp JA.

Biochim Biophys Acta. 1990 May 9;1024(1):189-92.

PMID:
2337614
47.

Plasmodium knowlesi induces alterations in phosphatidylcholine and phosphatidylethanolamine molecular species composition of parasitized monkey erythrocytes.

Simões AP, Moll GN, Beaumelle B, Vial HJ, Roelofsen B, Op den Kamp JA.

Biochim Biophys Acta. 1990 Feb 28;1022(2):135-45.

PMID:
2306451
48.

Phospholipid asymmetry in the plasma membrane of malaria infected erythrocytes.

Moll GN, Vial HJ, Bevers EM, Ancelin ML, Roelofsen B, Comfurius P, Slotboom AJ, Zwaal RF, Op den Kamp JA, van Deenen LL.

Biochem Cell Biol. 1990 Feb;68(2):579-85.

PMID:
2344403
49.

Phospholipid uptake by Plasmodium knowlesi infected erythrocytes.

Moll GN, Vial HJ, Ancelin ML, Op den Kamp JA, Roelofsen B, van Deenen LL.

FEBS Lett. 1988 May 23;232(2):341-6.

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