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Items: 1 to 50 of 139

1.

The Configuration of Distaminolyne A is S: Quantitative Evaluation of Exciton Coupling Circular Dichroism of N, O- Bis-arenoyl-1-amino-2-alkanols.

Molinski TF, Salib MN, Pearce AN, Copp BR.

J Nat Prod. 2019 May 24;82(5):1183-1189. doi: 10.1021/acs.jnatprod.8b00937. Epub 2019 Apr 8.

PMID:
30958674
2.

Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †.

Jamison MT, Wang X, Cheng T, Molinski TF.

Mar Drugs. 2019 Feb 7;17(2). pii: E102. doi: 10.3390/md17020102.

3.

Enantiomeric Variability of Distaminolyne A. Refinement of ECD and NMR Methods for Determining Optical Purity of 1-Amino-2-Alkanols.

Pearce AN, Copp BR, Molinski TF.

Molecules. 2018 Dec 27;24(1). pii: E90. doi: 10.3390/molecules24010090.

4.

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):248-249. doi: 10.1039/c8np90041h. Epub 2018 Nov 23.

5.

6-Bromoindole Derivatives from the Icelandic Marine Sponge Geodia barretti: Isolation and Anti-Inflammatory Activity.

Di X, Rouger C, Hardardottir I, Freysdottir J, Molinski TF, Tasdemir D, Omarsdottir S.

Mar Drugs. 2018 Nov 8;16(11). pii: E437. doi: 10.3390/md16110437.

6.

Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth.

de Souza RTMP, Freire VF, Gubiani JR, Ferreira RO, Trivella DBB, Moraes FC, Paradas WC, Salgado LT, Pereira RC, Amado Filho GM, Ferreira AG, Williams DE, Andersen RJ, Molinski TF, Berlinck RGS.

J Nat Prod. 2018 Oct 26;81(10):2296-2300. doi: 10.1021/acs.jnatprod.8b00533. Epub 2018 Oct 3.

PMID:
30281303
7.

Lepadins I-K, 3- O-(3'-Methylthio)acryloyloxy-decahydroquinoline Esters from a Bahamian Ascidian Didemnum sp. Assignment of Absolute Stereostructures.

Ómarsdóttir S, Wang X, Liu HB, Duggan BM, Molinski TF.

J Org Chem. 2018 Nov 16;83(22):13670-13677. doi: 10.1021/acs.joc.8b01609. Epub 2018 Oct 26.

8.

Resolution of Atropisomeric Cyclic Catechol Monoether O-Sulfate Esters by a Molluscan Sulfatase.

Masuno MN, Molinski TF.

ACS Omega. 2018 Jul 31;3(7):7771-7775. doi: 10.1021/acsomega.7b01899. Epub 2018 Jul 12.

9.

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):35-107. doi: 10.1039/c7np00064b. Epub 2018 Jul 13. Review. Erratum in: Nat Prod Rep. 2018 Nov 23;:.

10.

Six Trikentrin-like Cyclopentanoindoles from Trikentrion flabelliforme. Absolute Structural Assignment by NMR and ECD.

Salib MN, Molinski TF.

J Org Chem. 2018 Feb 2;83(3):1278-1286. doi: 10.1021/acs.joc.7b02813. Epub 2018 Jan 23.

11.

Liposomal Circular Dichroism (L-CD) of Arenoyl Derivatives of Sphingolipids. Amplification of Cotton Effects in Ordered Lipid Bilayers.

Molinski TF, Broaddus CD, Morinaka BI.

Mar Drugs. 2017 Dec 20;15(12). pii: E352. doi: 10.3390/md15120352.

12.

Isolation of bastadin-6-O-sulfate and expedient purifications of bastadins-4, -5 and -6 from extracts of Ianthella basta.

Gartshore CJ, Salib MN, Renshaw AA, Molinski TF.

Fitoterapia. 2018 Apr;126:16-21. doi: 10.1016/j.fitote.2017.12.003. Epub 2017 Dec 5.

13.

Cyclic azole-homologated peptides from Marine sponges.

Molinski TF.

Org Biomol Chem. 2017 Dec 19;16(1):21-29. doi: 10.1039/c7ob02628e. Review.

14.

Cyclic Hexapeptide Dimers, Antatollamides A and B, from the Ascidian Didemnum molle. A Tryptophan-Derived Auxiliary for l- and d-Amino Acid Assignments.

Salib MN, Molinski TF.

J Org Chem. 2017 Oct 6;82(19):10181-10187. doi: 10.1021/acs.joc.7b01659. Epub 2017 Sep 18.

15.

Synthesis and Structure Revision of Symplocin A.

Shao LP, Si CM, Mao ZY, Zhou W, Molinski TF, Wei BG, Lin GQ.

Org Chem Front. 2017 Jun 1;4(6):995-1004. doi: 10.1039/C7QO00052A. Epub 2017 Feb 9.

16.

Structure-activity of antifungal compounds inspired by aminobisabolenes from the sponge Halichondria sp.

Jamison MT, Macho J, Molinski TF.

Bioorg Med Chem Lett. 2016 Nov 1;26(21):5244-5246. doi: 10.1016/j.bmcl.2016.09.053. Epub 2016 Sep 22.

PMID:
27720294
17.

Band-Selective 2D HSQMBC: A Universal Technique for Detection and Measurement of 35,37Cl Isotope Effects for 13C Nuclei.

Saurí J, Reibarkh M, Zhang T, Cohen RD, Wang X, Molinski TF, Martin GE, Williamson RT.

Org Lett. 2016 Oct 7;18(19):4786-4789. Epub 2016 Sep 28.

PMID:
27681329
18.

Jamaicensamide A, a Peptide Containing β-Amino-α-keto and Thiazole-Homologated η-Amino Acid Residues from the Sponge Plakina jamaicensis.

Jamison MT, Molinski TF.

J Nat Prod. 2016 Sep 23;79(9):2243-9. doi: 10.1021/acs.jnatprod.6b00336. Epub 2016 Aug 22.

PMID:
27547840
19.

Ultra-high resolution band-selective HSQC for nanomole-scale identification of chlorine-substituted 13 C in natural products drug discovery.

Wang X, Duggan BM, Molinski TF.

Magn Reson Chem. 2017 Apr;55(4):263-268. doi: 10.1002/mrc.4415. Epub 2016 Mar 7.

20.

Peroxide Natural Products from Plakortis zyggompha and the Sponge Association Plakortis halichondrioides-Xestospongia deweerdtae: Antifungal Activity against Cryptococcus gattii.

Jamison MT, Dalisay DS, Molinski TF.

J Nat Prod. 2016 Mar 25;79(3):555-63. doi: 10.1021/acs.jnatprod.5b00951. Epub 2016 Feb 9.

PMID:
26859086
21.

Mollenynes B-E from the marine sponge Spirastrella mollis. Band-selective heteronuclear single quantum coherence for discrimination of bromo-chloro regioisomerism in natural products.

Wang X, Duggan BM, Molinski TF.

J Am Chem Soc. 2015 Sep 30;137(38):12343-51. doi: 10.1021/jacs.5b07858. Epub 2015 Sep 22.

PMID:
26336030
22.

Antipodal crambescin A2 homologues from the marine sponge Pseudaxinella reticulata. Antifungal structure-activity relationships.

Jamison MT, Molinski TF.

J Nat Prod. 2015 Mar 27;78(3):557-61. doi: 10.1021/np501052a. Epub 2015 Mar 4.

PMID:
25738226
23.

Cytotoxic effects on tumour cell lines of fatty acids from the marine sponge Scopalina ruetzleri.

Biegelmeyer R, Schröder R, Rambo DF, Dresch RR, Stout EP, Carraro JL, Mothes B, Moreira JC, Molinski TF, da Frota Junior ML, Henriques AT.

J Pharm Pharmacol. 2015 May;67(5):746-53. doi: 10.1111/jphp.12366. Epub 2015 Jan 5.

PMID:
25560902
24.

Salvadenosine, a 5'-deoxy-5'-(methylthio) nucleoside from the Bahamian tunicate Didemnum sp.

Jamison MT, Boddy CN, Molinski TF.

J Org Chem. 2014 Nov 7;79(21):9992-7. doi: 10.1021/jo501486p. Epub 2014 Oct 20.

25.

All natural: the renaissance of natural products chemistry.

Molinski TF.

Org Lett. 2014 Aug 1;16(15):3849-55. doi: 10.1021/ol501917g. No abstract available.

PMID:
25081565
26.

All natural: the renaissance of natural products chemistry.

Molinski TF.

J Org Chem. 2014 Aug 1;79(15):6765. doi: 10.1021/jo501288m. No abstract available.

PMID:
25081028
27.

Potent fluorinated agelastatin analogues for chronic lymphocytic leukemia: design, synthesis, and pharmacokinetic studies.

Stout EP, Choi MY, Castro JE, Molinski TF.

J Med Chem. 2014 Jun 26;57(12):5085-93. doi: 10.1021/jm4016922. Epub 2014 Jun 10.

28.

Interactions of antagonists with subtypes of inositol 1,4,5-trisphosphate (IP3) receptor.

Saleem H, Tovey SC, Molinski TF, Taylor CW.

Br J Pharmacol. 2014 Jul;171(13):3298-312. doi: 10.1111/bph.12685.

29.

Structures and solution conformational dynamics of stylissamides G and H from the Bahamian sponge Stylissa caribica.

Wang X, Morinaka BI, Molinski TF.

J Nat Prod. 2014 Mar 28;77(3):625-30. doi: 10.1021/np400891s. Epub 2014 Feb 27.

30.

INTEGRATED APPROACHES TO THE CONFIGURATIONAL ASSIGNMENT OF MARINE NATURAL PRODUCTS.

Molinski TF, Morinaka BI.

Tetrahedron. 2012 Nov 18;68(46):9307-9343. No abstract available.

31.

Acremolin from Acremonium strictum is N(2),3-etheno-2'-isopropyl-1-methylguanine, not a 1H-azirine. Synthesis and structural revision.

Januar LA, Molinski TF.

Org Lett. 2013 May 17;15(10):2370-3. doi: 10.1021/ol400752s. Epub 2013 May 1.

32.

Temperature-dependent conformations of a membrane supported zinc porphyrin tweezer by 2D fluorescence spectroscopy.

Widom JR, Lee W, Perdomo-Ortiz A, Rappoport D, Molinski TF, Aspuru-Guzik A, Marcus AH.

J Phys Chem A. 2013 Jul 25;117(29):6171-84. doi: 10.1021/jp400394z. Epub 2013 Mar 29.

33.

Halisphingosines A and B, modified sphingoid bases from Haliclona tubifera. Assignment of configuration by circular dichroism and van't Hoff's principle of optical superposition.

Molinski TF, Biegelmeyer R, Stout EP, Wang X, Frota ML Jr, Henriques AT.

J Nat Prod. 2013 Mar 22;76(3):374-81. doi: 10.1021/np300744y. Epub 2012 Dec 26.

34.

D-Glucosamine-derived synthons for assembly of L-threo-sphingoid bases. Total synthesis of rhizochalinin C.

Ko J, Molinski TF.

J Org Chem. 2013 Jan 18;78(2):498-505. doi: 10.1021/jo302355t. Epub 2012 Dec 27.

35.
36.

Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor.

Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD.

Proc Natl Acad Sci U S A. 2012 May 15;109(20):7923-8. doi: 10.1073/pnas.1119207109. Epub 2012 Apr 30.

37.

Pyrrole aminoimidazole alkaloid metabiosynthesis with marine sponges Agelas conifera and Stylissa caribica.

Stout EP, Wang YG, Romo D, Molinski TF.

Angew Chem Int Ed Engl. 2012 May 14;51(20):4877-81. doi: 10.1002/anie.201108119. Epub 2012 Apr 4.

38.

De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis.

Stout EP, Morinaka BI, Wang YG, Romo D, Molinski TF.

J Nat Prod. 2012 Apr 27;75(4):527-30. doi: 10.1021/np300051k. Epub 2012 Mar 28.

39.
40.

Mollenyne A, a long-chain chlorodibromohydrin amide from the sponge Spirastrella mollis.

Morinaka BI, Molinski TF.

Org Lett. 2011 Dec 16;13(24):6338-41. doi: 10.1021/ol2024778. Epub 2011 Nov 16.

41.

Phorboxazole Synthetic Studies: Design, Synthesis and Biological Evaluation of Phorboxazole A and Hemi-Phorboxazole A Related Analogues.

Smith AB 3rd, Hogan AM, Liu Z, Razler TM, Meis RM, Morinaka BI, Molinski TF.

Tetrahedron. 2011 Jul 8;67(27-28):5069-5078.

42.

Assembly of the isoindolinone core of muironolide A by asymmetric intramolecular Diels-Alder cycloaddition.

Flores B, Molinski TF.

Org Lett. 2011 Aug 5;13(15):3932-5. doi: 10.1021/ol201461n. Epub 2011 Jul 13.

43.

Preparation of α-amino acids by oxidative oxazoline-oxazinone rearrangement-hydrogenation (OOOH). Scope and limitations.

Liu C, Molinski TF.

Chem Asian J. 2011 Aug 1;6(8):2022-7. doi: 10.1002/asia.201100452. Epub 2011 Jul 12.

PMID:
21751407
44.

Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans.

Dalisay DS, Saludes JP, Molinski TF.

Bioorg Med Chem. 2011 Nov 15;19(22):6654-7. doi: 10.1016/j.bmc.2011.05.041. Epub 2011 May 27.

45.
46.

N,N'-methyleno-didemnin A from the ascidian Trididemnum solidum. Complete NMR assignments and confirmation of the imidazolidinone ring by strategic analysis of 1J(CH).

Molinski TF, Ko J, Reynolds KA, Lievens SC, Skarda KR.

J Nat Prod. 2011 Apr 25;74(4):882-7. doi: 10.1021/np100846s. Epub 2011 Feb 22.

47.

Faulknerynes A-C from a Bahamian sponge Diplastrella sp.: stereoassignment by critical application of two exciton coupled CD methods.

Ko J, Morinaka BI, Molinski TF.

J Org Chem. 2011 Feb 4;76(3):894-901. doi: 10.1021/jo102188q. Epub 2011 Jan 10.

48.

Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+.

Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski TF, Fruen BR, Allen PD, Perez CF.

J Biol Chem. 2010 Dec 3;285(49):38453-62. doi: 10.1074/jbc.M110.164525. Epub 2010 Oct 6.

49.

Microscale methodology for structure elucidation of natural products.

Molinski TF.

Curr Opin Biotechnol. 2010 Dec;21(6):819-26. doi: 10.1016/j.copbio.2010.09.003. Epub 2010 Sep 27. Review.

50.

Total synthesis of enigmazole A from Cinachyrella enigmatica. Bidirectional bond constructions with an ambident 2,4-disubstituted oxazole synthon.

Skepper CK, Quach T, Molinski TF.

J Am Chem Soc. 2010 Aug 4;132(30):10286-92. doi: 10.1021/ja1016975.

PMID:
20590095

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