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Items: 5


Perturbation biology nominates upstream-downstream drug combinations in RAF inhibitor resistant melanoma cells.

Korkut A, Wang W, Demir E, Aksoy BA, Jing X, Molinelli EJ, Babur Ö, Bemis DL, Onur Sumer S, Solit DB, Pratilas CA, Sander C.

Elife. 2015 Aug 18;4. doi: 10.7554/eLife.04640.


Spatial normalization of reverse phase protein array data.

Kaushik P, Molinelli EJ, Miller ML, Wang W, Korkut A, Liu W, Ju Z, Lu Y, Mills G, Sander C.

PLoS One. 2014 Dec 12;9(12):e97213. doi: 10.1371/journal.pone.0097213. eCollection 2014.


Perturbation biology: inferring signaling networks in cellular systems.

Molinelli EJ, Korkut A, Wang W, Miller ML, Gauthier NP, Jing X, Kaushik P, He Q, Mills G, Solit DB, Pratilas CA, Weigt M, Braunstein A, Pagnani A, Zecchina R, Sander C.

PLoS Comput Biol. 2013;9(12):e1003290. doi: 10.1371/journal.pcbi.1003290. Epub 2013 Dec 19.


Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets.

Miller ML, Molinelli EJ, Nair JS, Sheikh T, Samy R, Jing X, He Q, Korkut A, Crago AM, Singer S, Schwartz GK, Sander C.

Sci Signal. 2013 Sep 24;6(294):ra85. doi: 10.1126/scisignal.2004014.


Modeling local and global intracellular calcium responses mediated by diffusely distributed inositol 1,4,5-trisphosphate receptors.

Williams GS, Molinelli EJ, Smith GD.

J Theor Biol. 2008 Jul 7;253(1):170-88. doi: 10.1016/j.jtbi.2008.02.040. Epub 2008 Mar 6.


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