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Items: 41

1.

First passage events in biological systems with non-exponential inter-event times.

Castro M, López-García M, Lythe G, Molina-París C.

Sci Rep. 2018 Oct 10;8(1):15054. doi: 10.1038/s41598-018-32961-7.

2.

Quantifying the phosphorylation timescales of receptor-ligand complexes: a Markovian matrix-analytic approach.

López-García M, Nowicka M, Bendtsen C, Lythe G, Ponnambalam S, Molina-París C.

Open Biol. 2018 Sep 19;8(9). pii: 180126. doi: 10.1098/rsob.180126.

3.

Some deterministic and stochastic mathematical models of naïve T-cell homeostasis.

Lythe G, Molina-París C.

Immunol Rev. 2018 Sep;285(1):206-217. doi: 10.1111/imr.12696.

PMID:
30129198
4.

A Novel Stochastic Multi-Scale Model of Francisella tularensis Infection to Predict Risk of Infection in a Laboratory.

Carruthers J, López-García M, Gillard JJ, Laws TR, Lythe G, Molina-París C.

Front Microbiol. 2018 Jul 6;9:1165. doi: 10.3389/fmicb.2018.01165. eCollection 2018.

5.

A window of opportunity for cooperativity in the T Cell Receptor.

Martin-Blanco N, Blanco R, Alda-Catalinas C, Bovolenta ER, Oeste CL, Palmer E, Schamel WW, Lythe G, Molina-París C, Castro M, Alarcon B.

Nat Commun. 2018 Jul 5;9(1):2618. doi: 10.1038/s41467-018-05050-6.

6.

Role of genetic heterogeneity in determining the epidemiological severity of H1N1 influenza.

Sambaturu N, Mukherjee S, López-García M, Molina-París C, Menon GI, Chandra N.

PLoS Comput Biol. 2018 Mar 21;14(3):e1006069. doi: 10.1371/journal.pcbi.1006069. eCollection 2018 Mar.

7.

Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach.

Metri R, Mohan A, Nsengimana J, Pozniak J, Molina-Paris C, Newton-Bishop J, Bishop D, Chandra N.

Sci Rep. 2017 Dec 11;7(1):17314. doi: 10.1038/s41598-017-17330-0.

8.

A unifying mathematical framework for experimental TCR-pMHC kinetic constants.

Faro J, Castro M, Molina-París C.

Sci Rep. 2017 Apr 26;7:46741. doi: 10.1038/srep46741.

9.

A new mechanism shapes the naïve CD8+ T cell repertoire: the selection for full diversity.

Gonçalves P, Ferrarini M, Molina-Paris C, Lythe G, Vasseur F, Lim A, Rocha B, Azogui O.

Mol Immunol. 2017 May;85:66-80. doi: 10.1016/j.molimm.2017.01.026. Epub 2017 Mar 8.

10.

Continuous Effector CD8(+) T Cell Production in a Controlled Persistent Infection Is Sustained by a Proliferative Intermediate Population.

Chu HH, Chan SW, Gosling JP, Blanchard N, Tsitsiklis A, Lythe G, Shastri N, Molina-París C, Robey EA.

Immunity. 2016 Jul 19;45(1):159-71. doi: 10.1016/j.immuni.2016.06.013. Epub 2016 Jul 12.

11.

Stochastic descriptors to study the fate and potential of naive T cell clonotypes in the periphery.

Artalejo JR, Gómez-Corral A, López-García M, Molina-París C.

J Math Biol. 2017 Feb;74(3):673-708. doi: 10.1007/s00285-016-1020-6. Epub 2016 Jun 27.

12.

Mathematics in modern immunology.

Castro M, Lythe G, Molina-París C, Ribeiro RM.

Interface Focus. 2016 Apr 6;6(2):20150093. doi: 10.1098/rsfs.2015.0093. Review.

13.

How many TCR clonotypes does a body maintain?

Lythe G, Callard RE, Hoare RL, Molina-París C.

J Theor Biol. 2016 Jan 21;389:214-24. doi: 10.1016/j.jtbi.2015.10.016. Epub 2015 Nov 7.

14.

Asymmetric cell division during T cell development controls downstream fate.

Pham K, Shimoni R, Charnley M, Ludford-Menting MJ, Hawkins ED, Ramsbottom K, Oliaro J, Izon D, Ting SB, Reynolds J, Lythe G, Molina-Paris C, Melichar H, Robey E, Humbert PO, Gu M, Russell SM.

J Cell Biol. 2015 Sep 14;210(6):933-50. doi: 10.1083/jcb.201502053.

15.

Modeling early events in Francisella tularensis pathogenesis.

Gillard JJ, Laws TR, Lythe G, Molina-París C.

Front Cell Infect Microbiol. 2014 Dec 11;4:169. doi: 10.3389/fcimb.2014.00169. eCollection 2014.

16.

Receptor Pre-Clustering and T cell Responses: Insights into Molecular Mechanisms.

Castro M, van Santen HM, Férez M, Alarcón B, Lythe G, Molina-París C.

Front Immunol. 2014 Apr 30;5:132. doi: 10.3389/fimmu.2014.00132. eCollection 2014. Review.

17.

From pre-DP, post-DP, SP4, and SP8 Thymocyte Cell Counts to a Dynamical Model of Cortical and Medullary Selection.

Sawicka M, Stritesky GL, Reynolds J, Abourashchi N, Lythe G, Molina-París C, Hogquist KA.

Front Immunol. 2014 Feb 14;5:19. doi: 10.3389/fimmu.2014.00019. eCollection 2014.

18.

Mathematical Model of Naive T Cell Division and Survival IL-7 Thresholds.

Reynolds J, Coles M, Lythe G, Molina-París C.

Front Immunol. 2013 Dec 23;4:434. doi: 10.3389/fimmu.2013.00434. eCollection 2013.

19.

A mathematical perspective on CD4(+) T cell quorum-sensing.

Reynolds J, Amado IF, Freitas AA, Lythe G, Molina-París C.

J Theor Biol. 2014 Apr 21;347:160-75. doi: 10.1016/j.jtbi.2013.12.019. Epub 2013 Dec 31.

PMID:
24389364
20.

How many dendritic cells are required to initiate a T-cell response?

Celli S, Day M, Müller AJ, Molina-Paris C, Lythe G, Bousso P.

Blood. 2012 Nov 8;120(19):3945-8. doi: 10.1182/blood-2012-01-408260. Epub 2012 Sep 20.

21.

A stochastic T cell response criterion.

Currie J, Castro M, Lythe G, Palmer E, Molina-París C.

J R Soc Interface. 2012 Nov 7;9(76):2856-70. Epub 2012 Jun 28.

22.

Quorum-Sensing in CD4(+) T Cell Homeostasis: A Hypothesis and a Model.

Almeida AR, Amado IF, Reynolds J, Berges J, Lythe G, Molina-París C, Freitas AA.

Front Immunol. 2012 May 25;3:125. doi: 10.3389/fimmu.2012.00125. eCollection 2012.

23.

Proofreading of misincorporated nucleotides in DNA transcription.

Voliotis M, Cohen N, Molina-París C, Liverpool TB.

Phys Biol. 2012 Jun;9(3):036007. doi: 10.1088/1478-3975/9/3/036007. Epub 2012 May 29.

PMID:
22643861
24.

Proofreading of misincorporated nucleotides in DNA transcription.

Voliotis M, Cohen N, Molina-París C, Liverpool TB.

Phys Biol. 2012 Jun;9(3):036002. doi: 10.1088/1478-3975/9/3/036002. Epub 2012 May 3. Corrected and republished in: Phys Biol. 2012 Jun;9(3):036007.

PMID:
22551978
25.

Specific T-cell activation in an unspecific T-cell repertoire.

Van Den Berg HA, Molina-París C, Sewell AK.

Sci Prog. 2011;94(Pt 3):245-64. Review.

PMID:
22026148
26.

An integrative model for vascular endothelial growth factor A as a tumour biomarker.

Latham AM, Molina-París C, Homer-Vanniasinkam S, Ponnambalam S.

Integr Biol (Camb). 2010 Sep;2(9):397-407. doi: 10.1039/c0ib00008f. Epub 2010 Aug 20. Review.

PMID:
20725676
27.

Stochastic competitive exclusion in the maintenance of the naïve T cell repertoire.

Stirk ER, Lythe G, van den Berg HA, Molina-París C.

J Theor Biol. 2010 Aug 7;265(3):396-410. doi: 10.1016/j.jtbi.2010.05.004. Epub 2010 May 13.

PMID:
20471403
28.

The limiting conditional probability distribution in a stochastic model of T cell repertoire maintenance.

Stirk ER, Lythe G, van den Berg HA, Hurst GA, Molina-París C.

Math Biosci. 2010 Apr;224(2):74-86. doi: 10.1016/j.mbs.2009.12.004. Epub 2010 Jan 6.

PMID:
20060005
29.

Backtracking and proofreading in DNA transcription.

Voliotis M, Cohen N, Molina-París C, Liverpool TB.

Phys Rev Lett. 2009 Jun 26;102(25):258101. Epub 2009 Jun 22.

PMID:
19659121
30.

Stochastic niche structure and diversity maintenance in the T cell repertoire.

Stirk ER, Molina-París C, van den Berg HA.

J Theor Biol. 2008 Nov 21;255(2):237-49. doi: 10.1016/j.jtbi.2008.07.017. Epub 2008 Jul 24.

PMID:
18692074
31.

Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells.

Dunn S, Morrison EE, Liverpool TB, Molina-París C, Cross RA, Alonso MC, Peckham M.

J Cell Sci. 2008 Apr 1;121(Pt 7):1085-95. doi: 10.1242/jcs.026492. Epub 2008 Mar 11.

32.

Fluctuations, pauses, and backtracking in DNA transcription.

Voliotis M, Cohen N, Molina-París C, Liverpool TB.

Biophys J. 2008 Jan 15;94(2):334-48. Epub 2007 Aug 24.

33.

Minority memory genomes can influence the evolution of HIV-1 quasispecies in vivo.

Briones C, de Vicente A, Molina-París C, Domingo E.

Gene. 2006 Dec 15;384:129-38. Epub 2006 Aug 23.

PMID:
17059869
34.

Tumor growth instability and the onset of invasion.

Castro M, Molina-París C, Deisboeck TS.

Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Oct;72(4 Pt 1):041907. Epub 2005 Oct 6.

PMID:
16383420
35.

[Effectiveness of a recuperative primary care intervention in patients with chronic obstructive pulmonary disease].

Molina París J, Molina París C, de Lucas Ramos P, Lobo Alvarez MA, Calvo Corbella E, Lumbreras García G.

Aten Primaria. 2005 Jun 15;36(1):39-44. Spanish.

PMID:
15946614
36.

Memory in retroviral quasispecies: experimental evidence and theoretical model for human immunodeficiency virus.

Briones C, Domingo E, Molina-París C.

J Mol Biol. 2003 Aug 1;331(1):213-29.

PMID:
12875847
37.

Large-scale features of rotating forced turbulence.

Gaite J, Hochberg D, Molina-París C.

Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Feb;67(2 Pt 2):026304. Epub 2003 Feb 10.

PMID:
12636797
38.

The inflationary perturbation spectrum.

Habib S, Heitmann K, Jungman G, Molina-París C.

Phys Rev Lett. 2002 Dec 31;89(28 Pt 1):281301. Epub 2002 Dec 27.

PMID:
12513131
39.

Effective action for stochastic partial differential equations.

Hochberg D, Molina-París C, Pérez-Mercader J, Visser M.

Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1999 Dec;60(6 Pt A):6343-60.

PMID:
11970549
40.

Duration and fitness dependence of quasispecies memory.

Ruíz-Jarabo CM, Arias A, Molina-París C, Briones C, Baranowski E, Escarmís C, Domingo E.

J Mol Biol. 2002 Jan 18;315(3):285-96.

PMID:
11786012
41.

Heat kernel regularization of the effective action for stochastic reaction-diffusion equations.

Hochberg D, Molina-París C, Visser M.

Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Mar;63(3 Pt 2):036132. Epub 2001 Feb 27.

PMID:
11308734

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