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South Asian Cardiovascular Disease & Cancer Risk: Genetics & Pathophysiology.

Palaniappan L, Garg A, Enas E, Lewis H, Bari S, Gulati M, Flores C, Mathur A, Molina C, Narula J, Rahman S, Leng J, Gany F.

J Community Health. 2018 Jun 12. doi: 10.1007/s10900-018-0527-8. [Epub ahead of print]


Efficacy and Safety of Ticagrelor in Relation to Aspirin Use Within the Week Before Randomization in the SOCRATES Trial.

Wong KSL, Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Himmelmann A, Kasner SE, Knutsson M, Ladenvall P, Minematsu K, Molina CA, Wang Y, Johnston SC; SOCRATES Steering Committee and Investigators.

Stroke. 2018 Jul;49(7):1678-1685. doi: 10.1161/STROKEAHA.118.020553. Epub 2018 Jun 18.


Coflex interspinous implant placement leading to synovial cyst development: case report.

Ramhmdani S, Comair M, Molina CA, Sciubba DM, Bydon A.

J Neurosurg Spine. 2018 Jun 15:1-6. doi: 10.3171/2018.1.SPINE171360. [Epub ahead of print]


Association of high 5-hydroxymethylcytosine levels with Ten Eleven Translocation 2 overexpression and inflammation in Sjögren's syndrome patients.

Lagos C, Carvajal P, Castro I, Jara D, González S, Aguilera S, Barrera MJ, Quest AFG, Bahamondes V, Molina C, Urzúa U, Hermoso MA, Leyton C, González MJ.

Clin Immunol. 2018 Jun 9. pii: S1521-6616(18)30348-6. doi: 10.1016/j.clim.2018.06.002. [Epub ahead of print]


Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjögren's syndrome.

Barrera MJ, Aguilera S, Castro I, González S, Carvajal P, Molina C, Hermoso MA, González MJ.

Autoimmun Rev. 2018 Jun 8. pii: S1568-9972(18)30131-9. doi: 10.1016/j.autrev.2018.02.009. [Epub ahead of print] Review.


Deacylative alkylation (DaA) of N-methyl-3-acetyl-2-oxindole for the synthesis of symmetrically 3,3-disubstituted 2-oxindoles. An access gate to anticancer agents and natural products.

Moreno-Cabrerizo C, Ortega-Martínez A, Molina C, Nájera C, Sansano JM.

An Acad Bras Cienc. 2018;90(1 Suppl 2):1089-1099. doi: 10.1590/0001-3765201820170783.


Unexpected timely fracture union in matrix metalloproteinase 9 deficient mice.

Yuasa M, Saito M, Molina C, Moore-Lotridge SN, Benvenuti MA, Mignemi NA, Okawa A, Yoshii T, Schwartz HS, Nyman JS, Schoenecker JG.

PLoS One. 2018 May 31;13(5):e0198088. doi: 10.1371/journal.pone.0198088. eCollection 2018.


Whole-transcriptome analysis reveals genetic factors underlying flowering time regulation in rapeseed (Brassica napus L.).

Shah S, Weinholdt C, Jedrusik N, Molina C, Zou J, Große I, Schiessl S, Jung C, Emrani N.

Plant Cell Environ. 2018 Aug;41(8):1935-1947. doi: 10.1111/pce.13353. Epub 2018 Jun 19.


Diagnostic accuracy of Onen's Alternative Grading System combined with Doppler evaluation of ureteral jets as an alternative in the diagnosis of obstructive hydronephrosis in children.

de Bessa J Jr, Rodrigues CM, Chammas MC, Miranda EP, Gomes CM, Moscardi PR, Bessa MC, Molina CA, Tiraboschi RB, Netto JM, Denes FT.

PeerJ. 2018 May 18;6:e4791. doi: 10.7717/peerj.4791. eCollection 2018.


Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke.

Amarenco P, Lavallée PC, Monteiro Tavares L, Labreuche J, Albers GW, Abboud H, Anticoli S, Audebert H, Bornstein NM, Caplan LR, Correia M, Donnan GA, Ferro JM, Gongora-Rivera F, Heide W, Hennerici MG, Kelly PJ, Král M, Lin HF, Molina C, Park JM, Purroy F, Rothwell PM, Segura T, Školoudík D, Steg PG, Touboul PJ, Uchiyama S, Vicaut É, Wang Y, Wong LKS; Investigators.

N Engl J Med. 2018 Jun 7;378(23):2182-2190. doi: 10.1056/NEJMoa1802712. Epub 2018 May 16.


GPU-accelerated iterative reconstruction for limited-data tomography in CBCT systems.

de Molina C, Serrano E, Garcia-Blas J, Carretero J, Desco M, Abella M.

BMC Bioinformatics. 2018 May 15;19(1):171. doi: 10.1186/s12859-018-2169-3.


A neural pathway controlling motivation to exert effort.

Proulx CD, Aronson S, Milivojevic D, Molina C, Loi A, Monk B, Shabel SJ, Malinow R.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):5792-5797. doi: 10.1073/pnas.1801837115. Epub 2018 May 11.


Minimally invasive versus conventional spine surgery for vertebral metastases: a systematic review of the evidence.

Pennington Z, Ahmed AK, Molina CA, Ehresman J, Laufer I, Sciubba DM.

Ann Transl Med. 2018 Mar;6(6):103. doi: 10.21037/atm.2018.01.28. Review.


Impaired IRE1α/XBP-1 pathway associated to DNA methylation might contribute to salivary gland dysfunction in Sjögren's syndrome patients.

Sepúlveda D, Barrera MJ, Castro I, Aguilera S, Carvajal P, Lagos C, González S, Albornoz N, Bahamondes V, Quest AFG, Urzúa U, Molina C, Leyton C, Hermoso MA, González MJ.

Rheumatology (Oxford). 2018 Jun 1;57(6):1021-1032. doi: 10.1093/rheumatology/key021.


Applicability of Laparoscopic Nephrectomy in the Treatment of Multicystic Dysplastic Kidney: Sorting Out Surgical Indication.

Molina CAF, Bessa Junior J, Estevanato AG, Viana GS, Facincani I, Netto JMB, Tucci Junior S.

Cureus. 2018 Jan 1;10(1):e2014. doi: 10.7759/cureus.2014.


Expression profile of endothelin receptors (ETA and ETB) and microRNAs-155 and -199 in the corpus cavernosum of rats submitted to chronic alcoholism and diabetes mellitus.

Gonçalves FZ, Lizarte Neto FS, Novais PC, Gattas D, Lourenço LG, de Carvalho CAM, Tirapelli DPC, Molina CAF, Tirapelli LF, Tucci S Jr.

Braz J Med Biol Res. 2018 Mar 1;51(3):e6329. doi: 10.1590/1414-431X20176329.


Usefulness of ADAMTS13 to predict response to recanalization therapies in acute ischemic stroke.

Bustamante A, Ning M, García-Berrocoso T, Penalba A, Boada C, Simats A, Pagola J, Ribó M, Molina C, Lo E, Montaner J.

Neurology. 2018 Mar 20;90(12):e995-e1004. doi: 10.1212/WNL.0000000000005162. Epub 2018 Feb 14.


Lack of Early Improvement Predicts Poor Outcome Following Acute Intracerebral Hemorrhage.

Yogendrakumar V, Smith EE, Demchuk AM, Aviv RI, Rodriguez-Luna D, Molina CA, Silva Blas Y, Dzialowski I, Kobayashi A, Boulanger JM, Lum C, Gubitz G, Padma V, Roy J, Kase CS, Bhatia R, Ali M, Lyden P, Hill MD, Dowlatshahi D; Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign [PREDICT]/Sunnybrook ICH CTA Study Group and the Virtual International Stroke Trials Archive (VISTA)-ICH Collaborators.

Crit Care Med. 2018 Apr;46(4):e310-e317. doi: 10.1097/CCM.0000000000002962.


Percentage change in hemoglobin level and morbidity in spine surgery patients.

Purvis TE, Goodwin CR, Molina CA, Frank SM, Sciubba DM.

J Neurosurg Spine. 2018 Mar;28(3):345-351. doi: 10.3171/2017.7.SPINE17301. Epub 2017 Dec 22.


Agglomerated novel spray-dried lactose-leucine tailored as a carrier to enhance the aerosolization performance of salbutamol sulfate from DPI formulations.

Molina C, Kaialy W, Chen Q, Commandeur D, Nokhodchi A.

Drug Deliv Transl Res. 2017 Dec 19. doi: 10.1007/s13346-017-0462-8. [Epub ahead of print]


Elevated urinary CRELD2 is associated with endoplasmic reticulum stress-mediated kidney disease.

Kim Y, Park SJ, Manson SR, Molina CA, Kidd K, Thiessen-Philbrook H, Perry RJ, Liapis H, Kmoch S, Parikh CR, Bleyer AJ, Chen YM.

JCI Insight. 2017 Dec 7;2(23). pii: 92896. doi: 10.1172/jci.insight.92896. [Epub ahead of print]


Primary Thrombectomy in tPA (Tissue-Type Plasminogen Activator) Eligible Stroke Patients With Proximal Intracranial Occlusions.

Fischer U, Kaesmacher J, Molina CA, Selim MH, Alexandrov AV, Tsivgoulis G.

Stroke. 2018 Jan;49(1):265-269. doi: 10.1161/STROKEAHA.117.018564. Epub 2017 Dec 6. No abstract available.


Transfusion of Red Blood Cells Stored More Than 28 Days is Associated With Increased Morbidity Following Spine Surgery.

Purvis TE, Goodwin CR, Molina CA, Frank SM, Sciubba DM.

Spine (Phila Pa 1976). 2018 Jul 1;43(13):947-953. doi: 10.1097/BRS.0000000000002464.


Prehospital Systolic Blood Pressure Is Related to Intracerebral Hemorrhage Volume on Admission.

Rodriguez-Luna D, Rodriguez-Villatoro N, Juega JM, Boned S, Muchada M, Sanjuan E, Pagola J, Rubiera M, Ribo M, Coscojuela P, Molina CA.

Stroke. 2018 Jan;49(1):204-206. doi: 10.1161/STROKEAHA.117.018485. Epub 2017 Nov 22.


Do Intracerebral Hemorrhage Nonexpanders Actually Expand Into the Ventricular Space?

Dowlatshahi D, Deshpande A, Aviv RI, Rodriguez-Luna D, Molina CA, Blas YS, Dzialowski I, Kobayashi A, Boulanger JM, Lum C, Gubitz GJ, Padma V, Roy J, Kase CS, Bhatia R, Hill MD, Demchuk AM; PREDICT ICH CTA Study Group.

Stroke. 2018 Jan;49(1):201-203. doi: 10.1161/STROKEAHA.117.018716. Epub 2017 Nov 22.


Comparative Pan-Genome Analysis of Piscirickettsia salmonis Reveals Genomic Divergences within Genogroups.

Nourdin-Galindo G, Sánchez P, Molina CF, Espinoza-Rojas DA, Oliver C, Ruiz P, Vargas-Chacoff L, Cárcamo JG, Figueroa JE, Mancilla M, Maracaja-Coutinho V, Yañez AJ.

Front Cell Infect Microbiol. 2017 Oct 31;7:459. doi: 10.3389/fcimb.2017.00459. eCollection 2017.


Particulate matter levels in a South American megacity: the metropolitan area of Lima-Callao, Peru.

Silva J, Rojas J, Norabuena M, Molina C, Toro RA, Leiva-Guzmán MA.

Environ Monit Assess. 2017 Nov 13;189(12):635. doi: 10.1007/s10661-017-6327-2.


CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8+ T Cell-Relevant Genes.

Aznar MA, Labiano S, Diaz-Lagares A, Molina C, Garasa S, Azpilikueta A, Etxeberria I, Sanchez-Paulete AR, Korman AJ, Esteller M, Sandoval J, Melero I.

Cancer Immunol Res. 2018 Jan;6(1):69-78. doi: 10.1158/2326-6066.CIR-17-0159. Epub 2017 Nov 13.


Evaluation of three chemical immobilization protocols in golden-headed lion tamarins (Leontopithecus chrysomelas) undergoing vasectomy surgery.

Ferraro MA, Molina CV, Catão-Dias JL, Kierulff MCM, Pissinatti A, Bueno MG, Cortopassi SRG.

J Med Primatol. 2018 Apr;47(2):101-109. doi: 10.1111/jmp.12322. Epub 2017 Nov 8.


Applying inbreeding, hybridization and mutagenesis to improve oxidative stress tolerance and longevity of the entomopathogenic nematode Heterorhabditis bacteriophora.

Sumaya NH, Gohil R, Okolo C, Addis T, Doerfler V, Ehlers RU, Molina C.

J Invertebr Pathol. 2018 Jan;151:50-58. doi: 10.1016/j.jip.2017.11.001. Epub 2017 Nov 16.


Yield of atrial fibrillation detection with Textile Wearable Holter from the acute phase of stroke: Pilot study of Crypto-AF registry.

Pagola J, Juega J, Francisco-Pascual J, Moya A, Sanchis M, Bustamante A, Penalba A, Usero M, Cortijo E, Arenillas JF, Calleja AI, Sandin-Fuentes M, Rubio J, Mancha F, Escudero-Martinez I, Moniche F, de Torres R, Pérez-Sánchez S, González-Matos CE, Vega Á, Pedrote AA, Arana-Rueda E, Montaner J, Molina CA; CryptoAF investigators.

Int J Cardiol. 2018 Jan 15;251:45-50. doi: 10.1016/j.ijcard.2017.10.063. Epub 2017 Oct 22.


The effect of plasma rich in growth factors combined with follicular unit extraction surgery for the treatment of hair loss: A pilot study.

Navarro RM, Pino A, Martinez-Andres A, Molina C, Martinez AM, Martinez N, Orive G, Anitua E.

J Cosmet Dermatol. 2017 Oct 26. doi: 10.1111/jocd.12446. [Epub ahead of print]


Relationship between asymmetric dimethylarginine, nitrite and genetic polymorphisms: Impact on erectile dysfunction therapy.

Azevedo AMM, Brites-Anselmi G, Pinheiro LC, de Almeida Belo V, Coeli-Lacchini FB, Molina CAF, de Andrade MF, Tucci S Jr, Hirsch E, Tanus-Santos JE, Lacchini R.

Nitric Oxide. 2017 Dec 1;71:44-51. doi: 10.1016/j.niox.2017.10.006. Epub 2017 Oct 23.


Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart.

Molina CE, Jacquet E, Ponien P, Muñoz-Guijosa C, Baczkó I, Maier LS, Donzeau-Gouge P, Dobrev D, Fischmeister R, Garnier A.

Cardiovasc Res. 2018 Feb 1;114(2):247-258. doi: 10.1093/cvr/cvx182.


Off-Label Use of Direct Oral Anticoagulants in Intracerebral Hemorrhage Patients With Prosthetic Valves.

Chaturvedi S, Molina CA, Selim MH, Diener HC, Hohnloser SH.

Stroke. 2017 Nov;48(11):3183-3186. doi: 10.1161/STROKEAHA.117.017592. Epub 2017 Oct 13. No abstract available.


Systematic Review of the Outcomes of Surgical Treatment of Prostate Metastases to the Spine.

Clarke MJ, Molina CA, Fourney DR, Fisher CG, Gokaslan ZL, Schmidt MH, Rhines LD, Fehlings MG, Laufer I, Patel SR, Rampersaud YR, Reynolds J, Chou D, Bettegowda C, Mendel E, Weber MH, Sciubba DM.

Global Spine J. 2017 Aug;7(5):460-468. doi: 10.1177/2192568217710911. Epub 2017 Jun 1. Review.


Mercury contamination level and speciation inventory in Lakes Titicaca & Uru-Uru (Bolivia): Current status and future trends.

Guédron S, Point D, Acha D, Bouchet S, Baya PA, Tessier E, Monperrus M, Molina CI, Groleau A, Chauvaud L, Thebault J, Amice E, Alanoca L, Duwig C, Uzu G, Lazzaro X, Bertrand A, Bertrand S, Barbraud C, Delord K, Gibon FM, Ibanez C, Flores M, Fernandez Saavedra P, Ezpinoza ME, Heredia C, Rocha F, Zepita C, Amouroux D.

Environ Pollut. 2017 Dec;231(Pt 1):262-270. doi: 10.1016/j.envpol.2017.08.009. Epub 2017 Aug 12.


Prothrombin Complex Concentrates Use in Intracerebral Hemorrhage.

Poli S, Härtig F, Selim MH, Molina CA, Dowlatshahi D.

Stroke. 2017 Sep;48(9):2644-2646. doi: 10.1161/STROKEAHA.117.017591. Epub 2017 Aug 7. No abstract available.


Ticagrelor Versus Aspirin in Acute Embolic Stroke of Undetermined Source.

Amarenco P, Albers GW, Denison H, Easton JD, Evans SR, Held P, Hill MD, Jonasson J, Kasner SE, Ladenvall P, Minematsu K, Molina CA, Wang Y, Wong KSL, Johnston SC; SOCRATES Steering Committee and Investigators.

Stroke. 2017 Sep;48(9):2480-2487. doi: 10.1161/STROKEAHA.117.017217. Epub 2017 Jul 18.


FUX-Sim: Implementation of a fast universal simulation/reconstruction framework for X-ray systems.

Abella M, Serrano E, Garcia-Blas J, García I, de Molina C, Carretero J, Desco M.

PLoS One. 2017 Jul 10;12(7):e0180363. doi: 10.1371/journal.pone.0180363. eCollection 2017.


Multiphase CT Angiography Improves Prediction of Intracerebral Hemorrhage Expansion.

Rodriguez-Luna D, Coscojuela P, Rodriguez-Villatoro N, Juega JM, Boned S, Muchada M, Pagola J, Rubiera M, Ribo M, Tomasello A, Demchuk AM, Goyal M, Molina CA.

Radiology. 2017 Dec;285(3):932-940. doi: 10.1148/radiol.2017162839. Epub 2017 Jul 3.


On selection in finite populations.

Molina C, Earn DJD.

J Math Biol. 2018 Feb;76(3):645-678. doi: 10.1007/s00285-017-1151-4. Epub 2017 Jun 29.


Risk for Major Bleeding in Patients Receiving Ticagrelor Compared With Aspirin After Transient Ischemic Attack or Acute Ischemic Stroke in the SOCRATES Study (Acute Stroke or Transient Ischemic Attack Treated With Aspirin or Ticagrelor and Patient Outcomes).

Easton JD, Aunes M, Albers GW, Amarenco P, Bokelund-Singh S, Denison H, Evans SR, Held P, Jahreskog M, Jonasson J, Minematsu K, Molina CA, Wang Y, Wong KSL, Johnston SC; SOCRATES Steering Committee and Investigators.

Circulation. 2017 Sep 5;136(10):907-916. doi: 10.1161/CIRCULATIONAHA.117.028566. Epub 2017 Jun 27.


Intensive Blood Pressure Lowering in Intracerebral Hemorrhage.

Anderson CS, Selim MH, Molina CA, Qureshi AI.

Stroke. 2017 Jul;48(7):2034-2037. doi: 10.1161/STROKEAHA.117.016185. Epub 2017 Jun 16. No abstract available.


Differences in Characteristics and Outcomes Between Asian and Non-Asian Patients in the

Hoshino T, Uchiyama S, Wong LKS, Sissani L, Albers GW, Bornstein NM, Caplan LR, Donnan GA, Ferro JM, Hennerici MG, Labreuche J, Lavallée PC, Molina C, Rothwell PM, Steg PG, Touboul PJ, Vicaut É, Amarenco P; Investigators.

Stroke. 2017 Jul;48(7):1779-1787. doi: 10.1161/STROKEAHA.117.016874. Epub 2017 Jun 5.


CD69 is a direct HIF-1α target gene in hypoxia as a mechanism enhancing expression on tumor-infiltrating T lymphocytes.

Labiano S, Meléndez-Rodríguez F, Palazón A, Teijeira Á, Garasa S, Etxeberria I, Aznar MÁ, Sánchez-Paulete AR, Azpilikueta A, Bolaños E, Molina C, de la Fuente H, Maiso P, Sánchez-Madrid F, de Landázuri MO, Aragonés J, Melero I.

Oncoimmunology. 2017 Jan 19;6(4):e1283468. doi: 10.1080/2162402X.2017.1283468. eCollection 2017.


Observed Cost and Variations in Short Term Cost-Effectiveness of Therapy for Ischemic Stroke in Interventional Management of Stroke (IMS) III.

Simpson KN, Simpson AN, Mauldin PD, Palesch YY, Yeatts SD, Kleindorfer D, Tomsick TA, Foster LD, Demchuk AM, Khatri P, Hill MD, Jauch EC, Jovin TG, Yan B, von Kummer R, Molina CA, Goyal M, Schonewille WJ, Mazighi M, Engelter ST, Anderson C, Spilker J, Carrozzella J, Ryckborst KJ, Janis LS, Broderick JP; Interventional Management of Stroke (IMS) III Investigators.

J Am Heart Assoc. 2017 May 8;6(5). pii: e004513. doi: 10.1161/JAHA.116.004513.


Does Physician Reimbursement Correlate to Risk in Orthopaedic Trauma?

Sathiyakumar V, Thakore RV, Molina CS, Obremskey WT, Sethi MK.

J Surg Orthop Adv. 2017 Spring;26(1):48-53.


Direct transfer to angiosuite to reduce door-to-puncture time in thrombectomy for acute stroke.

Ribo M, Boned S, Rubiera M, Tomasello A, Coscojuela P, Hernández D, Pagola J, Juega J, Rodriguez N, Muchada M, Rodriguez-Luna D, Molina CA.

J Neurointerv Surg. 2018 Mar;10(3):221-224. doi: 10.1136/neurintsurg-2017-013038. Epub 2017 Apr 26.


GRECOS Project (Genotyping Recurrence Risk of Stroke): The Use of Genetics to Predict the Vascular Recurrence After Stroke.

Fernández-Cadenas I, Mendióroz M, Giralt D, Nafria C, Garcia E, Carrera C, Gallego-Fabrega C, Domingues-Montanari S, Delgado P, Ribó M, Castellanos M, Martínez S, Freijo M, Jiménez-Conde J, Rubiera M, Alvarez-Sabín J, Molina CA, Font MA, Grau Olivares M, Palomeras E, Perez de la Ossa N, Martinez-Zabaleta M, Masjuan J, Moniche F, Canovas D, Piñana C, Purroy F, Cocho D, Navas I, Tejero C, Aymerich N, Cullell N, Muiño E, Serena J, Rubio F, Davalos A, Roquer J, Arenillas JF, Martí-Fábregas J, Keene K, Chen WM, Worrall B, Sale M, Arboix A, Krupinski J, Montaner J; GRECOS Study Group.

Stroke. 2017 May;48(5):1147-1153. doi: 10.1161/STROKEAHA.116.014322. Epub 2017 Apr 14.

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