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Items: 14


Loss-of-huntingtin in medial and lateral ganglionic lineages differentially disrupts regional interneuron and projection neuron subtypes and promotes Huntington's disease-associated behavioral, cellular and pathological hallmarks.

Mehler MF, Petronglo JR, Arteaga-Bracho EE, Gulinello M, Winchester ML, Pichamoorthy N, Young SK, DeJesus CD, Ishtiaq H, Gokhan S, Molero AE.

J Neurosci. 2019 Jan 9. pii: 2443-18. doi: 10.1523/JNEUROSCI.2443-18.2018. [Epub ahead of print]


Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease.

Arteaga-Bracho EE, Gulinello M, Winchester ML, Pichamoorthy N, Petronglo JR, Zambrano AD, Inocencio J, De Jesus CD, Louie JO, Gokhan S, Mehler MF, Molero AE.

Neurobiol Dis. 2016 Dec;96:144-155. doi: 10.1016/j.nbd.2016.09.006. Epub 2016 Sep 10.


Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease.

Molero AE, Arteaga-Bracho EE, Chen CH, Gulinello M, Winchester ML, Pichamoorthy N, Gokhan S, Khodakhah K, Mehler MF.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):5736-41. doi: 10.1073/pnas.1603871113. Epub 2016 May 2.


The role of H1 linker histone subtypes in preserving the fidelity of elaboration of mesendodermal and neuroectodermal lineages during embryonic development.

Nguyen GD, Gokhan S, Molero AE, Yang SM, Kim BJ, Skoultchi AI, Mehler MF.

PLoS One. 2014 May 6;9(5):e96858. doi: 10.1371/journal.pone.0096858. eCollection 2014.


Functions of huntingtin in germ layer specification and organogenesis.

Nguyen GD, Molero AE, Gokhan S, Mehler MF.

PLoS One. 2013 Aug 13;8(8):e72698. doi: 10.1371/journal.pone.0072698. eCollection 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/edee8dfa-6b2a-44f4-866a-098f186e27f0.


Selective roles of normal and mutant huntingtin in neural induction and early neurogenesis.

Nguyen GD, Gokhan S, Molero AE, Mehler MF.

PLoS One. 2013 May 14;8(5):e64368. doi: 10.1371/journal.pone.0064368. Print 2013.


Corepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions.

Abrajano JJ, Qureshi IA, Gokhan S, Molero AE, Zheng D, Bergman A, Mehler MF.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16685-90. doi: 10.1073/pnas.0906917107. Epub 2010 Sep 7.


Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease.

Molero AE, Gokhan S, Gonzalez S, Feig JL, Alexandre LC, Mehler MF.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21900-5. doi: 10.1073/pnas.0912171106. Epub 2009 Dec 2.


Risk of dementia associated with elevated plasma homocysteine in a latin american population.

Chacón IJ, Molero AE, Pino-Ramírez G, Luchsinger JA, Lee JH, Maestre GE.

Int J Alzheimers Dis. 2009 Aug 23;2009. pii: 632489. doi: 10.4061/2009/632489.


High prevalence of dementia in a Caribbean population.

Molero AE, Pino-Ramírez G, Maestre GE.

Neuroepidemiology. 2007;29(1-2):107-12. Epub 2007 Oct 16.


Total plasma homocysteine values among elderly subjects: findings from the Maracaibo Aging Study.

Molero AE, Altimari CC, Duran DA, Garcia E, Pino-Ramirez G, Maestre GE.

Clin Biochem. 2006 Oct;39(10):1007-15. Epub 2006 Aug 12.


The Maracaibo Aging Study: population and methodological issues.

Maestre GE, Pino-Ramírez G, Molero AE, Silva ER, Zambrano R, Falque L, Gamero MP, Sulbarán TA.

Neuroepidemiology. 2002 Jul-Aug;21(4):194-201.


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