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Items: 1 to 50 of 147

1.

Defining HIV-1 Envelope N-Glycan Microdomains through Site-Specific Heterogeneity Profiles.

Hargett AA, Wei Q, Knoppova B, Hall S, Huang ZQ, Prakash A, Green TJ, Moldoveanu Z, Raska M, Novak J, Renfrow MB.

J Virol. 2018 Dec 10;93(1). pii: e01177-18. doi: 10.1128/JVI.01177-18. Print 2019 Jan 1.

2.

Serial Galactose-Deficient IgA1 Levels in Children with IgA Nephropathy and Healthy Controls.

Sanders JT, Hastings MC, Moldoveanu Z, Novak J, Julian BA, Bursac Z, Wyatt RJ.

Int J Nephrol. 2017;2017:8210641. doi: 10.1155/2017/8210641. Epub 2017 Nov 26.

3.

Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy.

Yamada K, Huang ZQ, Raska M, Reily C, Anderson JC, Suzuki H, Ueda H, Moldoveanu Z, Kiryluk K, Suzuki Y, Wyatt RJ, Tomino Y, Gharavi AG, Weinmann A, Julian BA, Willey CD, Novak J.

Kidney Int Rep. 2017 Jul 19;2(6):1194-1207. doi: 10.1016/j.ekir.2017.07.002. eCollection 2017 Nov.

4.

Differences in serum IgA responses to HIV-1 gp41 in elite controllers compared to viral suppressors on highly active antiretroviral therapy.

Nabi R, Moldoveanu Z, Wei Q, Golub ET, Durkin HG, Greenblatt RM, Herold BC, Nowicki MJ, Kassaye S, Cho MW, Pinter A, Landay AL, Mestecky J, Kozlowski PA.

PLoS One. 2017 Jul 3;12(7):e0180245. doi: 10.1371/journal.pone.0180245. eCollection 2017.

5.

GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway.

Kiryluk K, Li Y, Moldoveanu Z, Suzuki H, Reily C, Hou P, Xie J, Mladkova N, Prakash S, Fischman C, Shapiro S, LeDesma RA, Bradbury D, Ionita-Laza I, Eitner F, Rauen T, Maillard N, Berthoux F, Floege J, Chen N, Zhang H, Scolari F, Wyatt RJ, Julian BA, Gharavi AG, Novak J.

PLoS Genet. 2017 Feb 10;13(2):e1006609. doi: 10.1371/journal.pgen.1006609. eCollection 2017 Feb.

6.

Galactose-Deficient IgA1 as a Candidate Urinary Polypeptide Marker of IgA Nephropathy?

Suzuki H, Allegri L, Suzuki Y, Hall S, Moldoveanu Z, Wyatt RJ, Novak J, Julian BA.

Dis Markers. 2016;2016:7806438. doi: 10.1155/2016/7806438. Epub 2016 Aug 28.

7.

IgA nephropathy enigma.

Mestecky J, Novak J, Moldoveanu Z, Raska M.

Clin Immunol. 2016 Nov;172:72-77. doi: 10.1016/j.clim.2016.07.011. Epub 2016 Jul 18. Review.

8.

The Origin and Activities of IgA1-Containing Immune Complexes in IgA Nephropathy.

Knoppova B, Reily C, Maillard N, Rizk DV, Moldoveanu Z, Mestecky J, Raska M, Renfrow MB, Julian BA, Novak J.

Front Immunol. 2016 Apr 12;7:117. doi: 10.3389/fimmu.2016.00117. eCollection 2016. Review.

9.

Characterization of serum antibodies from women immunized with Gardasil: A study of HPV-18 infection of primary human keratinocytes.

Wang HK, Wei Q, Moldoveanu Z, Huh WK, Vu HL, Broker TR, Mestecky J, Chow LT.

Vaccine. 2016 Jun 8;34(27):3171-3177. doi: 10.1016/j.vaccine.2016.04.038. Epub 2016 Apr 23.

10.

Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge.

Kutzler MA, Wise MC, Hutnick NA, Moldoveanu Z, Hunter M, Reuter M, Yuan S, Yan J, Ginsberg A, Sylvester A, Pahar B, Carnathan D, Kathuria N, Khan AS, Montefiori D, Sardesai NY, Betts MR, Mestecky J, Marx P, Weiner DB.

Mucosal Immunol. 2016 Jan;9(1):13-23. doi: 10.1038/mi.2015.31. Epub 2015 May 6.

11.

Origin of galactose-deficient immunoglobulin g in gingival crevicular fluid in periodontitis.

Komiyama Y, Kafkova LR, Barasch A, Shah GR, Grbic JT, Novak Z, Komiyama K, Novak J, Mestecky J, Moldoveanu Z.

J Periodontol. 2014 Dec;85(12):1779-85. doi: 10.1902/jop.2014.140212.

PMID:
25152004
12.

Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection.

Raska M, Czernekova L, Moldoveanu Z, Zachova K, Elliott MC, Novak Z, Hall S, Hoelscher M, Maboko L, Brown R, Smith PD, Mestecky J, Novak J.

AIDS Res Ther. 2014 Aug 1;11:23. doi: 10.1186/1742-6405-11-23. eCollection 2014.

13.

Enzymatic sialylation of IgA1 O-glycans: implications for studies of IgA nephropathy.

Takahashi K, Raska M, Stuchlova Horynova M, Hall SD, Poulsen K, Kilian M, Hiki Y, Yuzawa Y, Moldoveanu Z, Julian BA, Renfrow MB, Novak J.

PLoS One. 2014 Jun 11;9(2):e99026. doi: 10.1371/journal.pone.0099026. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e113577.

14.

Humoral immune responses to HIV in the mucosal secretions and sera of HIV-infected women.

Mestecky J, Wei Q, Alexander R, Raska M, Novak J, Moldoveanu Z.

Am J Reprod Immunol. 2014 Jun;71(6):600-7. doi: 10.1111/aji.12203. Epub 2014 Feb 5. Review.

15.

Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.

Suzuki H, Raska M, Yamada K, Moldoveanu Z, Julian BA, Wyatt RJ, Tomino Y, Gharavi AG, Novak J.

J Biol Chem. 2014 Feb 21;289(8):5330-9. doi: 10.1074/jbc.M113.512277. Epub 2014 Jan 7.

16.

The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells.

Gupta S, Gach JS, Becerra JC, Phan TB, Pudney J, Moldoveanu Z, Joseph SB, Landucci G, Supnet MJ, Ping LH, Corti D, Moldt B, Hel Z, Lanzavecchia A, Ruprecht RM, Burton DR, Mestecky J, Anderson DJ, Forthal DN.

PLoS Pathog. 2013;9(11):e1003776. doi: 10.1371/journal.ppat.1003776. Epub 2013 Nov 21. Erratum in: PLoS Pathog. 2013 Nov;9(11). doi:10.1371/annotation/31430955-703b-484a-96eb-e180f917d683.

17.

Biomarkers in IgA nephropathy: relationship to pathogenetic hits.

Hastings MC, Moldoveanu Z, Suzuki H, Berthoux F, Julian BA, Sanders JT, Renfrow MB, Novak J, Wyatt RJ.

Expert Opin Med Diagn. 2013 Nov;7(6):615-27. doi: 10.1517/17530059.2013.856878. Review.

18.

Comparative Evaluation of HIV-1 Neutralization in External Secretions and Sera of HIV-1-Infected Women.

Wei Q, Moldoveanu Z, Huang WQ, Alexander RC, Goepfert PA, Mestecky J.

Open AIDS J. 2012;6:293-302. doi: 10.2174/1874613601206010293. Epub 2012 Dec 28.

19.

IgA nephropathy: molecular mechanisms of the disease.

Mestecky J, Raska M, Julian BA, Gharavi AG, Renfrow MB, Moldoveanu Z, Novak L, Matousovic K, Novak J.

Annu Rev Pathol. 2013 Jan 24;8:217-40. doi: 10.1146/annurev-pathol-011110-130216. Epub 2012 Oct 18. Review.

PMID:
23092188
20.

Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathy.

Eison TM, Hastings MC, Moldoveanu Z, Sanders JT, Gaber L, Walker PD, Lau KK, Julian BA, Novak J, Wyatt RJ.

Clin Nephrol. 2012 Dec;78(6):465-9. doi: 10.5414/CN107423.

21.

Serum galactose-deficient IgA1 level is not associated with proteinuria in children with IgA nephropathy.

Hastings MC, Afshan S, Sanders JT, Kane O, Eison TM, Lau KK, Moldoveanu Z, Julian BA, Novak J, Wyatt RJ.

Int J Nephrol. 2012;2012:315467. doi: 10.1155/2012/315467. Epub 2012 Jun 17.

22.

The level of galactose-deficient IgA1 in the sera of patients with IgA nephropathy is associated with disease progression.

Zhao N, Hou P, Lv J, Moldoveanu Z, Li Y, Kiryluk K, Gharavi AG, Novak J, Zhang H.

Kidney Int. 2012 Oct;82(7):790-6. doi: 10.1038/ki.2012.197. Epub 2012 Jun 6.

23.

In vitro-generated immune complexes containing galactose-deficient IgA1 stimulate proliferation of mesangial cells.

Yanagihara T, Brown R, Hall S, Moldoveanu Z, Goepfert A, Tomana M, Julian BA, Mestecky J, Novak J.

Results Immunol. 2012 Jan 1;2:166-172.

24.

The pathophysiology of IgA nephropathy.

Suzuki H, Kiryluk K, Novak J, Moldoveanu Z, Herr AB, Renfrow MB, Wyatt RJ, Scolari F, Mestecky J, Gharavi AG, Julian BA.

J Am Soc Nephrol. 2011 Oct;22(10):1795-803. doi: 10.1681/ASN.2011050464. Epub 2011 Sep 23. Review.

25.

Aberrant glycosylation of IgA1 and anti-glycan antibodies in IgA nephropathy: role of mucosal immune system.

Novak J, Moldoveanu Z, Julian BA, Raska M, Wyatt RJ, Suzuki Y, Tomino Y, Gharavi AG, Mestecky J, Suzuki H.

Adv Otorhinolaryngol. 2011;72:60-3. doi: 10.1159/000324607. Epub 2011 Aug 18. Review.

PMID:
21865691
26.

IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cells.

Novak J, Raskova Kafkova L, Suzuki H, Tomana M, Matousovic K, Brown R, Hall S, Sanders JT, Eison TM, Moldoveanu Z, Novak L, Novak Z, Mayne R, Julian BA, Mestecky J, Wyatt RJ.

Nephrol Dial Transplant. 2011 Nov;26(11):3451-7. doi: 10.1093/ndt/gfr448. Epub 2011 Aug 9.

27.

Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schönlein purpura nephritis.

Kiryluk K, Moldoveanu Z, Sanders JT, Eison TM, Suzuki H, Julian BA, Novak J, Gharavi AG, Wyatt RJ.

Kidney Int. 2011 Jul;80(1):79-87. doi: 10.1038/ki.2011.16. Epub 2011 Feb 16.

28.

Scarcity or absence of humoral immune responses in the plasma and cervicovaginal lavage fluids of heavily HIV-1-exposed but persistently seronegative women.

Mestecky J, Wright PF, Lopalco L, Staats HF, Kozlowski PA, Moldoveanu Z, Alexander RC, Kulhavy R, Pastori C, Maboko L, Riedner G, Zhu Y, Wrinn T, Hoelscher M.

AIDS Res Hum Retroviruses. 2011 May;27(5):469-86. doi: 10.1089/aid.2010.0169. Epub 2010 Nov 22.

29.

Methods for evaluation of humoral immune responses in human genital tract secretions.

Mestecky J, Alexander RC, Wei Q, Moldoveanu Z.

Am J Reprod Immunol. 2011 Mar;65(3):361-7. doi: 10.1111/j.1600-0897.2010.00923.x. Epub 2010 Nov 19. Review.

30.

Galactose-deficient IgA1 in African Americans with IgA nephropathy: serum levels and heritability.

Hastings MC, Moldoveanu Z, Julian BA, Novak J, Sanders JT, McGlothan KR, Gharavi AG, Wyatt RJ.

Clin J Am Soc Nephrol. 2010 Nov;5(11):2069-74. doi: 10.2215/CJN.03270410. Epub 2010 Jul 15.

31.

Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: a comparative binding study.

Gomes MM, Suzuki H, Brooks MT, Tomana M, Moldoveanu Z, Mestecky J, Julian BA, Novak J, Herr AB.

Biochemistry. 2010 Jul 13;49(27):5671-82. doi: 10.1021/bi9019498.

32.

Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition.

Raska M, Takahashi K, Czernekova L, Zachova K, Hall S, Moldoveanu Z, Elliott MC, Wilson L, Brown R, Jancova D, Barnes S, Vrbkova J, Tomana M, Smith PD, Mestecky J, Renfrow MB, Novak J.

J Biol Chem. 2010 Jul 2;285(27):20860-9. doi: 10.1074/jbc.M109.085472. Epub 2010 May 3.

33.

Antibody-mediated protection and the mucosal immune system of the genital tract: relevance to vaccine design.

Mestecky J, Raska M, Novak J, Alexander RC, Moldoveanu Z.

J Reprod Immunol. 2010 May;85(1):81-5. doi: 10.1016/j.jri.2010.02.003. Epub 2010 Mar 16. Review.

34.

Familial IgA nephropathy in southeastern Kentucky.

Lavigne KA, Woodford SY, Barker CV, Julian BA, Novak J, Moldoveanu Z, Gharavi AG, Wyatt RJ.

Clin Nephrol. 2010 Feb;73(2):115-21.

35.

Expression of homing receptors on IgA1 and IgA2 plasmablasts in blood reflects differential distribution of IgA1 and IgA2 in various body fluids.

Pakkanen SH, Kantele JM, Moldoveanu Z, Hedges S, Häkkinen M, Mestecky J, Kantele A.

Clin Vaccine Immunol. 2010 Mar;17(3):393-401. doi: 10.1128/CVI.00475-09. Epub 2010 Jan 20.

36.

Mucosal immunology of the genital and gastrointestinal tracts and HIV-1 infection.

Mestecky J, Moldoveanu Z, Smith PD, Hel Z, Alexander RC.

J Reprod Immunol. 2009 Dec;83(1-2):196-200. doi: 10.1016/j.jri.2009.07.005. Epub 2009 Oct 23. Review.

37.

Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity.

Suzuki H, Fan R, Zhang Z, Brown R, Hall S, Julian BA, Chatham WW, Suzuki Y, Wyatt RJ, Moldoveanu Z, Lee JY, Robinson J, Tomana M, Tomino Y, Mestecky J, Novak J.

J Clin Invest. 2009 Jun;119(6):1668-77. doi: 10.1172/JCI38468. Epub 2009 May 26.

38.

Effect of flash-heat treatment on immunoglobulins in breast milk.

Chantry CJ, Israel-Ballard K, Moldoveanu Z, Peerson J, Coutsoudis A, Sibeko L, Abrams B.

J Acquir Immune Defic Syndr. 2009 Jul 1;51(3):264-7. doi: 10.1097/QAI.0b013e3181aa12f2.

39.

Mucosal antibody responses to HIV.

Moldoveanu Z, Mestecky J.

Methods Mol Biol. 2009;485:333-45. doi: 10.1007/978-1-59745-170-3_22.

PMID:
19020835
40.

Delivery of DNA HIV-1 vaccine to the liver induces high and long-lasting humoral immune responses.

Raska M, Moldoveanu Z, Novak J, Hel Z, Novak L, Bozja J, Compans RW, Yang C, Mestecky J.

Vaccine. 2008 Mar 17;26(12):1541-51. doi: 10.1016/j.vaccine.2008.01.035. Epub 2008 Feb 7.

41.

Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy.

Gharavi AG, Moldoveanu Z, Wyatt RJ, Barker CV, Woodford SY, Lifton RP, Mestecky J, Novak J, Julian BA.

J Am Soc Nephrol. 2008 May;19(5):1008-14. doi: 10.1681/ASN.2007091052. Epub 2008 Feb 13.

42.

Role of aberrant glycosylation of IgA1 molecules in the pathogenesis of IgA nephropathy.

Mestecky J, Tomana M, Moldoveanu Z, Julian BA, Suzuki H, Matousovic K, Renfrow MB, Novak L, Wyatt RJ, Novak J.

Kidney Blood Press Res. 2008;31(1):29-37. doi: 10.1159/000112922. Epub 2008 Jan 8. Review.

43.

IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1.

Suzuki H, Moldoveanu Z, Hall S, Brown R, Vu HL, Novak L, Julian BA, Tomana M, Wyatt RJ, Edberg JC, Alarcón GS, Kimberly RP, Tomino Y, Mestecky J, Novak J.

J Clin Invest. 2008 Feb;118(2):629-39. doi: 10.1172/JCI33189.

44.

Electrophoretic methods for analysis of urinary polypeptides in IgA-associated renal diseases.

Julian BA, Wittke S, Novak J, Good DM, Coon JJ, Kellmann M, Zürbig P, Schiffer E, Haubitz M, Moldoveanu Z, Calcatera SM, Wyatt RJ, Sýkora J, Sládková E, Hes O, Mischak H, McGuire BM.

Electrophoresis. 2007 Dec;28(23):4469-83.

PMID:
18004714
45.

Serum levels of galactose-deficient IgA in children with IgA nephropathy and Henoch-Schönlein purpura.

Lau KK, Wyatt RJ, Moldoveanu Z, Tomana M, Julian BA, Hogg RJ, Lee JY, Huang WQ, Mestecky J, Novak J.

Pediatr Nephrol. 2007 Dec;22(12):2067-72. Epub 2007 Oct 18.

PMID:
17943324
46.

Intranasal immunization with influenza virus and Korean mistletoe lectin C (KML-C) induces heterosubtypic immunity in mice.

Song SK, Moldoveanu Z, Nguyen HH, Kim EH, Choi KY, Kim JB, Mestecky J.

Vaccine. 2007 Aug 21;25(34):6359-66. Epub 2007 Jul 2.

PMID:
17640781
47.

IgA nephropathy and Henoch-Schoenlein purpura nephritis: aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cells.

Novak J, Moldoveanu Z, Renfrow MB, Yanagihara T, Suzuki H, Raska M, Hall S, Brown R, Huang WQ, Goepfert A, Kilian M, Poulsen K, Tomana M, Wyatt RJ, Julian BA, Mestecky J.

Contrib Nephrol. 2007;157:134-8. Review.

PMID:
17495451
48.

IgA nephropathy: characterization of IgG antibodies specific for galactose-deficient IgA1.

Suzuki H, Moldoveanu Z, Hall S, Brown R, Julian BA, Wyatt RJ, Tomana M, Tomino Y, Novak J, Mestecky J.

Contrib Nephrol. 2007;157:129-33. Review.

PMID:
17495450
49.

IgA nephropathy: current views of immune complex formation.

Mestecky J, Suzuki H, Yanagihara T, Moldoveanu Z, Tomana M, Matousovic K, Julian BA, Novak J.

Contrib Nephrol. 2007;157:56-63. Review.

PMID:
17495438
50.

IgA nephropathy: a clinical overview.

Julian BA, Wyatt RJ, Matousovic K, Moldoveanu Z, Mestecky J, Novak J.

Contrib Nephrol. 2007;157:19-26. Review.

PMID:
17495433

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